Clinical trials: sponsored by Galderma R&D
Nasolabial Folds
Safety and Effectiveness of Sculptra Aesthetic for Correction of Nasolabial Folds.
This study has been designed to evaluate the safety of Sculptra Aesthetic as a single regimen for correction of Nasolabial Fold (NLF) contour deficiencies after changes in reconstitution and injection procedures compared to the…
- Trial name
- NCT03780244
- Testing
- Sculptra Aesthetic 8ml, Sculptra Aesthetic 5ml
- Where
- 5 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Aesthetics
Safety and Efficacy of Azzalure/Dysport, Restylane/Emervel Filler and Restylane Skinbooster Treatment
The efficacy and safety, as well as subject satisfaction will be evaluated after single treatment with Azzalure/Dysport alone or Restylane/Emervel filler alone followed by repeated combined treatment with Azzalure/Dysport…
- Trial name
- NCT02297516
- Testing
- Azzalure or Dysport, Restylane or Emervel filler, Restylane Skinbooster
- Where
- 4 sites in Brazil, France and 1 more
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Chin Retrusion, Chin Augmentation
A Study to Evaluate the Safety and Efficacy of Restylane Defyne for Chin Augmentation and Correction of Chin Retrusion
To demonstrate the effectiveness of Restylane Defyne for chin augmentation and correction of chin retrusion by demonstrating the superiority in responder rates relative to no treatment.
- Trial name
- NCT03624816
- Testing
- Restylane Defyne
- Where
- 11 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Breast Enhancement
Macrolane VRF30 for Enhancement of Shape and Fullness of Female Breast
This is an open, multi-center, non comparative study to evaluate the safety and efficacy of Macrolane VRF30 in the female breast. 71 subjects have received initial treatment with a maximum of 120 ml of Macrolane VRF30 per breast.
- Trial name
- COBRA (NCT01299532)
- Testing
- Macrolane VRF30
- Where
- 5 sites in France, Sweden
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Breast Enhancement
Macrolane for Enhancement of the Shape and Fullness of the Female Breast
The study evaluates treatment procedure, efficacy and safety of Macrolane for female breast enhancement.
- Trial name
- NCT01308853
- Testing
- Macrolane
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Breast Augmentation
A 7-year Follow up of All Subjects Incuded in Protocol 31GB0106
Several subjects included in a Pilot study (CTN 31GB0106) during 2002-2003 still had Macrolane deposits in the breast when the last study visit was performed.
- Trial name
- NCT01146275
- Testing
- Radiologial breast examination
- Where
- 4 sites in Sweden
- Volunteers
- 6 people
- Sponsor
- Galderma R&D
Atrophy
Morphological and Functional Evaluation of Buttock Lipoatrophy Treatment With Macrolane
The study is being undertaken to establish the effectiveness and safety of Macrolane volume restoration factor 30 (VRF30) when used for treatment of HIV-infected subjects with buttocks lipoatrophy.
- Trial name
- NCT00931268
- Testing
- Macrolane VRF 30
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Galderma R&D
Volume Restoration and Shaping of the Buttocks
A Study to Evaluate Efficacy and Safety of Macrolane VRF30 for Volume Restoration and Contouring of the Buttocks
The purpose of the study is to evaluate the efficacy and safety of Macrolane for volume restoration and shaping of the buttocks.
- Trial name
- NCT01331408
- Testing
- Macrolane VRF30
- Where
- 4 sites in Belgium, Spain and 1 more
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Plaque Psoriasis
Subject Reported Target-lesion Numeric Rating Scale Evaluation by Subjects With Plaque Psoriasis Treated With Clobex® (Clobetasol Propionate) Spray 0.05%
The aim of this study is to investigate the utility of a technological based rating scale for assessing improvement in plaque psoriasis with Clobex spray treatment.
- Trial name
- NCT01893567
- Testing
- Clobex Spray
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Galderma R&D
Knee Osteoarthritis
Different Volumes of Durolane in Knee OA
The purpose of the study is to assess the safety and efficacy profiles of new single-injection volumes of Durolane in patients with knee OA.
- Trial name
- NCT01265459
- Testing
- Durolane 3 ml, Durolane 4,5 ml, Durolane 6 ml
- Where
- 3 sites in Sweden
- Volunteers
- 68 people
- Sponsor
- Galderma R&D
Facial Tissue Augmentation
A Study of Treatment Preference During Cheek Contouring Comparing Restylane® SubQ With and Without the Addition of Lidocaine Hydrochloride
The objectives of this study are to evaluate the pain-relieving effect and safety of adding lidocaine hydrochloride to Restylane SubQ and to evaluate the esthetic improvement obtained.
- Trial name
- NCT01431755
- Testing
- Restylane SubQ, Restylane SubQ Lidocaine
- Where
- 3 sites in Sweden
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Acne Vulgaris, Atrophic Acne Scars
Adapalene 0.3% - Benzoyl Peroxide 2.5% Gel and Risk of Formation of Atrophic Acne Scars
This was a multi-centre, randomized, investigator blinded, vehicle controlled trial using intra-individual comparison (right half-face versus left half-face).
- Trial name
- OSCAR (NCT02735421)
- Testing
- ABPO Forte Gel, Vehicle gel
- Where
- 7 sites in Canada, France
- Volunteers
- 67 people
- Sponsor
- Galderma R&D
Nasal Augmentation
Restylane Perlane to Shape the Nasal Dorsum and/or Nasal Root
The purpose of this study is to determine the safety and efficacy of using Restylane Perlane to shape the nasal dorsum and/or nasal root in comparison with a no-treatment control group
- Trial name
- NCT02216851
- Testing
- Restylane Perlane
- Where
- 2 sites in China
- Volunteers
- 132 people
- Sponsor
- Galderma R&D
Glabellar Frown Lines
Safety and Efficacy of AbobotulinumtoxinA for the Treatment of Glabellar Lines
An interventional phase 2 study to evaluate safety and efficacy of AbobotulinumtoxinA treatment for glabellar lines
- Trial name
- NCT03736928
- Testing
- AbobotulinumtoxinA dose level 1 or 2, AbobotulinumtoxinA dose 3, AbobotulinumtoxinA dose 4
- Where
- 10 sites in United States
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Injection Techniques
Study to Evaluate Efficacy, Safety and Injection Technique of Restylane Lip Volume and Restylane Lip Refresh
The purpose of this study is to demonstrate the efficacy and safety of two new Restylane Lip products, Restylane Lip Volume and Restylane Lip Refresh, and to collect information on the injection technique.
- Trial name
- NCT01428024
- Testing
- Restylane Lip Volume, Restylane Lip Refresh
- Where
- 3 sites in Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Cheek Augmentation
GAL1704 for Cheek Augmentation and Correction of Midface Contour Deficiencies
An interventional study to evaluate the safety and effectiveness of GAL1704 for cheek augmentation and the correction of midface volume deficiencies by demonstrating non-inferiority in change from baseline, relative to an active…
- Trial name
- NCT03700047
- Testing
- GAL1704, Juvederm Voluma
- Where
- 15 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Healthy Volunteers
Safety and Efficacy of Restylane Lidocaine and Restylane Perlane Lidocaine for Facial Augmentation in Asian Population
The purpose of this study is to evaluate the safety and efficacy of Restylane Lidocaine and Restylane Perlane Lidocaine after the first and second treatment when used for facial augmentation in Asian population.
- Trial name
- NCT02565784
- Testing
- Restylane, Perlane
- Where
- 2 sites in Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Acne Scars
An Open, Non-comparative Study of the Efficacy and Safety of Treatment of Acne Scars With Restylane Vital Lidocaine
The purpose of this study is to demonstrate the efficacy and safety of Restylane Vital Lidocaine when acne scars are treated
- Trial name
- NCT01807455
- Testing
- Restylane Vital Lidocaine
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Galderma R&D
Nasolabial Folds in Chinese Population
Efficacy and Safety of Restylane Perlane Compared to Restylane for Correction of Moderate and Severe Nasolabial Folds
The purpose of this study is to determine the safety and efficacy of using Restylane Perlane compared to Restylane for correction of moderate to severe nasolabial folds (NLF) in a Chinese population.
- Trial name
- NCT02432742
- Testing
- Restylane Perlane, Restylane
- Where
- 3 sites in China
- Volunteers
- 100 people
- Sponsor
- Galderma R&D
Facial Tissue Augmentation
Evaluation of Efficacy and Safety of Hyaluronic Acid (HA) Product for Cheek Augmentation
A multi-centre, evaluator-blinded study in subjects undergoing cheek augmentation. The study is designed to assess efficacy with regard to aesthetic midface augmentation and safety after treatment with HA product.
- Trial name
- NCT02396251
- Testing
- HA experimental, HA comparator
- Where
- 2 sites in Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Galderma R&D