Clinical trials: sponsored by Galderma R&D
Pectus Excavatum Deformity
Treatment of Pectus Excavatum Deformity Using Macrolane Filler
This is a prospective, open, non-comparative and baseline-controlled study to evaluate efficacy and safety of Macrolane VRF20 treatment in 40 subjects with pectus excavatum deformity.
- Trial name
- NCT01750112
- Testing
- Macrolane VRF20
- Where
- 2 sites in France, Sweden
- Volunteers
- 23 people
- Sponsor
- Galderma R&D
Wrinkles and Folds in Lower Face
Perception of Facial Expressions Following Correction of Wrinkles and Folds
The purpose of this study is to evaluate the perception of facial expressions following correction of wrinkles and folds in the lower face using Emervel Classic Lidocaine and Emervel Deep Lidocaine.
- Trial name
- NCT02573337
- Testing
- Emervel Classic Lidocaine, Emervel Deep Lidocaine
- Where
- 3 sites in Germany
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Glabellar Frown Lines
A Safety and Efficacy Study of Different Injections Volumes of Botulinum Toxin Type A, Azzalure, in the Glabellar Lines
A randomized, evaluator-blinded, comparative, study to evaluate the efficacy and safety of different injection volumes of botulinum toxin type A, Azzalure, in the glabellar lines.
- Trial name
- NCT02108158
- Testing
- Azzalure
- Where
- 2 sites in Sweden
- Volunteers
- 62 people
- Sponsor
- Galderma R&D
Chin Augmentation and Correction
New Dermal Filler for Chin Correction and Augmentation
Randomized, evaluator-blinded, no treatment controlled multicenter study to evaluate safety and effectiveness of GP0109 for augmentation and correction or retrusion in the chin region in Canada
- Trial name
- NCT04631263
- Testing
- Hyaluronic Acid
- Where
- 9 sites in Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Breast Augmentation
Swedish Macrolane Registry
A Registry to monitor long term safety in female subjects after treatment with Macrolane VRF20 and/or MacrolaneT VRF30 in the breasts.
- Trial name
- NCT01145235
- Where
- Sweden
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Local Tolerability After Lip Filler Injections
Safety and Efficacy of Lip Injections With Emervel Lips and Juvederm Ultra Smile
The purpose of this study is to demonstrate the efficacy and safety of Emervel Lips and Juvederm Ultra smile
- Trial name
- NCT01745250
- Testing
- Emervel Lips, Juvederm Ultra Smile
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Females Recently Treated With Macrolane VRF in the Breasts
Macrolane Prospective Survey
The study objective is to evaluate the long term safety when Macrolane Volume Restoration Factor is used in female breasts in clinical practice.
- Trial name
- NCT01223066
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Galderma R&D
Nasolabial Folds
A Post Market Evaluation After Treatment of Nasolabial Folds
This is an open, non-comparative study to evaluate effectiveness and safety of Restylane in correction of nasolabial folds up to 12 months after the initial treatment, and to evaluate the safety of repeat treatment of the…
- Trial name
- NCT02179736
- Testing
- Restylane
- Where
- China
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Unilateral Knee Osteoarthritis
Durolane Compared to Saline in Patients With Unilateral Knee Osteoarthritis
This was a study that compared Durolane injections to saline injections in the treatment of unilateral osteoarthritis of the knee.
- Trial name
- NCT01806207
- Testing
- Durolane injection, Saline injection
- Where
- United Kingdom
- Volunteers
- 218 people
- Sponsor
- Galderma R&D
Health Knowledge, Attitudes, Practice
A Non-interventional Study to Evaluate the Use of Pliaglis in Daily Practice
A multe-center, non-interventional study in Europe to evaluate Pliaglis in daily practice
- Trial name
- NCT01800474
- Where
- 4 sites in France, Germany and 2 more
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Aesthetics
Study to Evaluate Restylane Vital Light Using an Injector Device
The purpose of the study is to evaluate the safety and efficacy of Restylane Vital White administered with an injector device on aged skin in the face, hands and décolletage.
- Trial name
- NCT01412190
- Testing
- Restylane Vital Light, No treatment
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Scalp Psoriasis
Clobetasol Propionate Spray Versus Vehicle Spray for the Management of Moderate to Severe Plaque Psoriasis of the Scalp
The primary objective of this study is to evaluate the safety and efficacy of clobetasol propionate spray versus vehicle spray for the management of moderate to severe plaque psoriasis of the scalp.
- Trial name
- NCT00881868
- Testing
- clobetasol propionate spray 0.05%, Vehicle spray
- Where
- 4 sites in United States
- Volunteers
- 81 people
- Sponsor
- Galderma R&D
Knee Osteoarthritis
Durolane Versus Methylprednisolone in Knee Osteoarthritis
The primary objective is to determine whether Durolane is non-inferior to methylprednisolone, as assessed by level of pain, when each are given as single intra-articular injections for the relief of pain, in the treatment of…
- Trial name
- NCT01209364
- Testing
- Durolane is a device, methylprednisolone in a drug
- Where
- 23 sites in Canada, Sweden and 1 more
- Volunteers
- 442 people
- Sponsor
- Galderma R&D
Safety
A Study to Evaluate the Safety Following Injection of GP0045 Compared to Restylane Lyft Lidocaine
This is a study to assess the safety of GP0045 compared to Restylane Lyft Lidocaine. There is a 12-week follow-up period. AEs will be recorded throughout the study.
- Trial name
- NCT03133325
- Testing
- GP0045, Restylane Lyft Lidocaine
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Breast Enhancement
An Extension of CTN 31GB0607 to Evaluate Long Term Safety of NASHA Treatment in the Breast
The study evaluates degradation of NASHA in breast 4 and 6 years post treatment, long term safety and evaluation if a satisfactory breast cancer screening can be performed in subjects treated with NASHA-gel in breast.
- Trial name
- NCT01609400
- Volunteers
- 11 people
- Sponsor
- Galderma R&D
Cheek Wrinkles, Midface Contour Deficiencies
Safety and Effectiveness of GP0112 for Cheek Augmentation and Correction
A prospective, randomized, evaluator-blinded, comparator-controlled, parallel group, multicenter study to evaluate the safety and effectiveness of GP0112 for cheek augmentation and correction of midface contour deficiencies
- Trial name
- NCT05098457
- Testing
- GP0112, Restylane Lyft Lidocaine
- Where
- 8 sites in Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Galderma R&D
Erythema, Rosacea
Efficacy and Safety Study Comparing CD07805/47 Gel 0.5% to Azelaic Acid Gel 15% in Subjects With Erythema of Rosacea
The purpose of this study is to compare the efficacy and assess the safety of CD07805/47 gel 0.5% applied topically once daily versus azelaic acid gel 15% applied topically twice daily in subjects with moderate to severe facial…
- Trial name
- NCT01659853
- Testing
- CD07805/47 gel 0.5%/CD07805/47 Vehicle, azelaic acid gel 15%
- Where
- 4 sites in United States
- Volunteers
- 70 people
- Sponsor
- Galderma R&D
Lip Filler Injections
Safety and Efficacy Study of Lip Injections With Emervel Lips Lidocaine and Juvéderm Volbella With Lidocaine
A 12-month, randomised, evaluator-blinded, comparative, multicentre study of the safety and efficacy of lip injections with Emervel Lips Lidocaine and Juvéderm Volbella with Lidocaine.
- Trial name
- NCT01916278
- Testing
- Emervel Lips Lidocaine, Juvéderma Volbella with Lidocaine
- Where
- 3 sites in Germany, Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Galderma R&D
Skin Manifestations
Tolerability Comparison Between Differin® Cream 0.1% Versus Differin® Lotion 0.1% in Subjects With Healthy Skin
The purpose of this study is to compare the tolerability of Differin® (adapalene) Cream, 0.1% to Differin® Lotion, 0.1% in subjects with healthy skin treated once a day for three (3) weeks.
- Trial name
- NCT01046565
- Testing
- adapalene cream 0.1%, adapalene lotion 0.1%
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Knee Osteoarthritis
Dose-Escalation of Botulinum Toxin in Subjects With Osteoarthritis of the Knee
The purpose of the study is to evaluate the safety and tolerability of the drug product at each dose level.
- Trial name
- NCT02139319
- Testing
- Botulinum toxin
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Galderma R&D