Clinical trials: sponsored by Georgetown University
Cancer, Small Cell Lung Cancer
A Phase I/II Study of Ganetespib in Combination With Doxorubicin
This is a Phase I/safety dose expansion study of the combination of the drug ganetespib and doxorubicin in patients with advanced solid tumors.
- Trial name
- NCT02261805
- Testing
- Ganetespib, Doxorubicin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Georgetown University
Breast Cancer
Gene Expression in Tumor Tissue From Women Undergoing Surgery for Breast Cancer or Core Biopsy of the Breast
RATIONALE: Studying samples of breast tissue in the laboratory may help doctors learn more about the genes and proteins found in breast tissue.
- Trial name
- NCT00898937
- Testing
- microarray analysis, breast biopsy
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Georgetown University
Breast Cancer, DCIS
CyberKnife Stereotactic Accelerated Partial Breast Irradiation (SAPBI)
This study will prospectively evaluate the technical feasibility, acute toxicity, late effects and oncologic outcomes of CyberKnife Stereotactic Accelerated Partial Breast Irradiation (CK-SAPBI) in early stage breast cancer.
- Conditions
- Breast Cancer, DCIS, Invasive Ductal Carcinoma
- Trial name
- CK-SAPBI (NCT02365714)
- Testing
- CK Stereotactic Accelerated Partial Breast Irradiation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Georgetown University
Schizophrenia
Use of Galantamine and CDP-choline (Citicoline) to Treat Adults With Schizophrenia
This study will evaluate the effectiveness of galantamine and CDP-choline in improving symptoms associated with schizophrenia.
- Trial name
- STAR-1 (NCT00509067)
- Testing
- Galantamine, CDP-choline, risperidone, olanzapine, quetiapine, ziprasidone, and/or aripiprazole
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Georgetown University
Pancreatic Cancer
Molecularly Tailored Therapy for Pancreas Cancer
Patient therapy is tailored according to the molecular profile of the patient's tumor.
- Trial name
- NCT01888978
- Testing
- Gem-OX, Gem-5FU, Gem-Tax
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Georgetown University
Buprenorphine, Pain
The Effects of Opioid Taper on Opioid-Induced Hyperalgesia
Evidence to support the effectiveness of ongoing opioid therapy for the treatment of chronic non-malignant pain is lacking. In fact, data suggest that patient outcomes improve when tapered off opioid analgesics.
- Trial name
- NCT03063905
- Testing
- Buprenorphine
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Georgetown University
Hip Injuries
Use of Regional Anesthesia in Hip Arthroscopy
The purpose of this research is to determine differences in outcomes in patients who do, or do not, receive regional anesthesia (a fascia iliaca block) prior to undergoing hip arthroscopy with labral repair and/or debridement and…
- Trial name
- NCT02851888
- Testing
- Ropivacaine, General Anesthesia
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Georgetown University
Prostate Cancer, Physical Activity
An Exercise Intervention for Prostate Cancer Patients Receiving Androgen Deprivation Therapy
This main purpose of this study is to examine the effects of an exercise intervention to counteract adverse side effects related to Androgen Deprivation Therapy (ADT) in prostate cancer patients.
- Conditions
- Prostate Cancer, Physical Activity, Side-effects
- Trial name
- MIGHTY (NCT02248350)
- Testing
- Supervised and Home Based Exercise, Stretching Control Group
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Georgetown University
Breast Cancer
Dovitinib Plus an Aromatase Inhibitor for Metastatic Breast Cancer
This study is for women with confirmed hormone receptor positive HER-2 negative advanced breast cancer with evidence of disease resistance to an aromatase inhibitor.
- Trial name
- NCT01484041
- Testing
- Dovitinib, Aromatase Inhibitors
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Georgetown University
Trauma
Enhanced Consent for Symptom Provocation Research
The overall goal of the proposed study is to insure the protection and safety of human subjects who have been previously exposed to interpersonal traumatic events and who are participants in symptom provocation research.
- Trial name
- NCT01809899
- Testing
- Enhanced consent procedure, Consent as Usual
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Phase I Study of Lenalidomide, Rituximab and Ibrutinib in Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)
This study is for subjects diagnosed with recurrent or relapsed CLL/SLL. The purpose of this study is to test the safety of the combination of the drugs lenalidomide and ibrutinib at different dose levels, in combination with the…
- Trial name
- NCT02200848
- Testing
- Lenalidomide, Ibrutinib, Rituximab
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Georgetown University
Smoking Cessation
Quit and Fit: A Tobacco Cessation and Energy Balance Pilot for African Americans
The Quit \& Fit intervention will be designed as a 12-week study to promote smoking cessation, increase physical activity levels, and reduce weight gain through regular exercise and healthy nutrition for African American Women…
- Trial name
- Quit and Fit (NCT02103582)
- Testing
- Intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Pediatric Cancer
Survivor Health and Resilience Education
An intervention to assist pediatric cancer survivors to behaviorally manage late effects.
- Trial name
- NCT03327025
- Testing
- Health education counseling
- Volunteers
- 17 people
- Sponsor
- Georgetown University
Breast Cancer
Psychosocial Intervention Pilot for Partners in BRCA Testing
A brief psychosocial intervention for partners of women affected by or at risk for breast cancer and harboring BRCA genetic alterations.
- Trial name
- NCT03323333
- Testing
- psychosocial counseling
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Heart Failure
Patient Self Monitoring to Evaluate 30 Day Post Discharge Heart Failure Outcomes
The purpose of this study is to examine the relative predictive ability of the derived monitoring instrument to determine post discharge instability and 30-day outcomes in patients discharged with HF.
- Trial name
- NCT02527759
- Testing
- Survey
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- Georgetown University
Anomia, Aphasia
Cognitive Therapy to Improve Word Finding
Adults who sustain brain damage due to stroke, traumatic injury or surgery may develop difficulty finding words. This study compares the effectiveness of two behavior-based programs to improve picture naming ability in these…
- Conditions
- Anomia, Aphasia, Traumatic Brain Injury, Cerebrovascular Accident
- Trial name
- NCT00494520
- Testing
- Errorful training condition, Errorless training condition
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Georgetown University
Diarrhea, Malaria
Impact Evaluation of Community-Based Health Programs in Rwanda
Community Health Clubs to improve local sanitation, hygiene and health conditions have been implemented in several countries in Africa and Asia with some success.
- Trial name
- CBEHPP (NCT01836731)
- Testing
- Classic Intervention, Minimum Intervention
- Where
- 2 sites in Rwanda
- Volunteers
- 8,718 people
- Sponsor
- Georgetown University
Aphasia
Using Transcranial Direct Current Stimulation (tDCS) to Improve Post-Stroke Aphasia
This study tests whether weak electrical stimulation of the brain is effective in improving language or reading difficulties occurring after a brain injury or stroke.
- Trial name
- NCT01709383
- Testing
- Transcranial Direct Current Stimulation
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- Georgetown University
Breast Cancer
Breast Health in Chinese American Women
This four-and-a-half-year study will test the efficacy of viewing a theoretically based and culturally sensitive video followed by group discussion (vs. single viewing) in increasing mammography use.
- Trial name
- NCT01292200
- Testing
- watch DVD and small group discussion, watch DVD
- Where
- 3 sites in United States
- Volunteers
- 954 people
- Sponsor
- Georgetown University
Unspecified Childhood Solid Tumor, Protocol Specific
Telephone-Based Cancer Education With or Without Telephone-Based Counseling in Young Participants
RATIONALE: Telephone-based cancer education and counseling may help participants learn about ways of preventing cancer and choose a lifestyle that will help them stay healthy as they grow older.
- Trial name
- NCT00459238
- Testing
- counseling intervention, educational intervention
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Georgetown University