Clinical trials: sponsored by Georgetown University
Colon Cancer
A Pilot Trial of GI-4000 Plus Bevacizumab and Either FOLFOX or FOLFIRI
The purpose of this study is to test the safety of GI-4000 and see what effects (good and bad) it has against cancer over time. This study is also being done to measure the immune response to GI-4000.
- Trial name
- NCT01322815
- Testing
- chemotherapy and GI-4000, GI-4000
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Georgetown University
Colorectal Cancer, Pancreas Cancer
Maintenance Dovitinib for Colorectal and Pancreas Cancer
This study is for patients with stage 4 colon cancer who have had initial chemotherapy or had surgery to remove metastases and patients with pancreas cancer, which has been surgically removed and are receiving adjuvant…
- Trial name
- NCT01888965
- Testing
- Dovitinib
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Georgetown University
Breast Neoplasms
Exemestane and Celecoxib in Postmenopausal Women at High Risk for Breast Cancer
The primary goal of this 5-year study is to determine whether exemestane alone or in combination with celecoxib decreases breast tissue density in healthy postmenopausal women at high risk for breast cancer.
- Trial name
- NCT00073073
- Testing
- Exemestane, Calcium carbonate, Vitamin D
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Georgetown University
Systemic Sclerosis, Scleroderma
Multi-center, Web Based Observational Study of Pulmonary Hypertension in Scleroderma Patients
The purpose of this study is to determine the timeline of progression from pre-pulmonary hypertension to diagnosable pulmonary hypertension based on right heart catheterization.
- Conditions
- Systemic Sclerosis, Scleroderma, Pulmonary Hypertension, Pulmonary Arterial Hypertension
- Trial name
- NCT00377949
- Where
- 25 sites in United States
- Volunteers
- 602 people
- Sponsor
- Georgetown University
Advanced Solid Tumors
Lapatinib and Bortezomib in Patients With Advanced Malignancies
This study is for patients with an advanced type of cancer for which no curative treatment exists. The purpose of this study is to test the safety and efficacy of the combination of the study drugs, lapatinib and bortezomib.
- Trial name
- NCT01497626
- Testing
- Lapatinib and bortezomib
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Georgetown University
Unspecified Adult Solid Tumor, Protocol Specific
Internet and Telephone Counseling for Smoking Cessation
RATIONALE: Computer-assisted stop-smoking plans and telephone counseling may help people stop smoking. It is not yet known which computer-based smoking cessation program is more effective with or without telephone counseling in…
- Trial name
- NCT00282009
- Testing
- Basic Internet, Enhanced Internet, Enhanced Internet + phone
- Where
- United States
- Volunteers
- 2,205 people
- Sponsor
- Georgetown University
Parkinson's Disease
A Double Blind Placebo Controlled Trial Evaluating Rasagiline Effects on Cognition in Parkinson's Disease Patients With Mild Cognitive Impairment Receiving Dopaminergic Therapy
The present pilot study is designed to assess the extent to which rasagiline may improve cognition in Parkinson's disease patients requiring dopaminergic therapy.
- Trial name
- RECOGNIZE (NCT01497652)
- Testing
- Rasagiline
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Georgetown University
Spasticity Secondary to Either a Disorder or Trauma, Spinal Cord Injury (SCI)
Myobloc Atrophy Study
The present pilot study is designed to assess the extent to which BOTOX and MYOBLOC cause muscle atrophy in spastic patients. The primary objective is to assess whether there is statistically significant difference in muscle…
- Conditions
- Spasticity Secondary to Either a Disorder or Trauma, Spinal Cord Injury (SCI), Brain Injury, Tumor
- Trial name
- MAS (NCT02052024)
- Testing
- Botox, MYOBLOC
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Georgetown University
Parkinson's Disease, Parkinson's Disease Dementia
Nilotinib in Cognitively Impaired Parkinson Disease Patients 001
This pilot study will test Nilotinib's ability to alter the abnormal protein build up in Parkinson disease and Diffuse Lewey Body Disease patients . Patients will receive Nilotinib at different doses for 6 months.
- Conditions
- Parkinson's Disease, Parkinson's Disease Dementia, Diffuse Lewy Body Disease
- Trial name
- NCT02281474
- Testing
- Nilotinib
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Ofatumumab and Bendamustine for Previously Treated Chronic Lymphocytic Leukemia (CLL)
The purpose of this study is to evaluate the safety and effectiveness of the combination of bendamustine and ofatumumab in subjects with relapsed/refractory chronic lymphocytic leukemia and small cell lymphoma.
- Trial name
- NCT01010568
- Testing
- Ofatumumab and Bendamustine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Georgetown University
Pancreas Cancer
Study of Pemetrexed for Second-Line Pancreas Cancer
This study is for patients with pancreatic cancer that has grown and/or spread after having previously received the standard chemotherapy drug called gemcitabine. In this study a drug called pemetrexed is being tested.
- Trial name
- NCT00864513
- Testing
- pemetrexed
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Georgetown University
Lung Neoplasm
Reader Study of DeltaView™ Chest Radiograph Software
A new software product takes two chest radiographs, aligns them, and then subtracts one image from the other. The resulting image represents an image showing any differences between them.
- Trial name
- NCT01261507
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Georgetown University
Hepatitis B
Evaluating Blood Glucose Levels During Infusion With HepaGam B (HBIG) in Post-liver Transplant Patients
HepaGam B Hepatitis B Immune Globulin (HBIG) solution contains 10% maltose, which could possibly interfere with the measurement of glucose levels when using glucose non-specific tests.
- Trial name
- NCT00998426
- Testing
- glucose monitoring before and after HepaGam B administration, HepaGam B (Hepatitis B Immune Globulin (HBIG))
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Georgetown University
Gestational Diabetes
Pilot Study of Exenatide Pharmacokinetics and Pharmacodynamics in Gestational Diabetes
This study is being done to study how exenatide, an FDA-approved drug that lowers blood sugar in non-pregnant patients with type II diabetes, works in pregnant women.
- Trial name
- NCT00572689
- Testing
- Exenatide, Buccal/blood Sample Collection
- Where
- 2 sites in United States
- Sponsor
- Georgetown University
Cancer
Cancer, Vulnerability, and Financial Quality of Life: A Mixed Methods Study
The primary purpose of this study is to examine how vulnerabilities in psychological and social situations affect financial quality of life.
- Trial name
- NCT01169545
- Volunteers
- 90 people
- Sponsor
- Georgetown University
Arteriovenous Access Grafts or Extra-anatomic and Infra-inguinal Grafts
Vascular Sealant Study
Study Objective:To evaluate the safety and effectiveness of the Vascular Sealant compared with Gelfoam/Thrombin when used to seal bleeding anastomotic suture lines in patients undergoing vascular reconstructive surgery requiring…
- Trial name
- VSS (NCT00618358)
- Testing
- Vascular Sealant System, Gelfoam/Thrombin
- Where
- United States
- Sponsor
- Georgetown University
Head and Neck Cancer
Study Using Pharmacogenetics to Select Treatment for Head and Neck Cancer
This is a study for patients with head and neck cancer who will be receiving chemotherapy and radiation therapy for their disease.
- Trial name
- PGx-SELECT (NCT00881114)
- Testing
- Cisplatin, Cetuximab
- Sponsor
- Georgetown University
End Stage Renal Disease, Hyperhomocysteinemia
Randomized Study of Folic Acid Therapy for Hyperhomocysteinemia in Patients With End Stage Renal Disease Receiving Hemodialysis
OBJECTIVES: I. Compare the efficacy of two doses of folic acid in normalizing plasma total homocysteine concentration in patients with end stage renal disease receiving regular hemodialysis therapy resulting in…
- Trial name
- NCT00004495
- Testing
- cyanocobalamin, folic acid, pyridoxine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Georgetown University
Oral Cancer
A Study of the Effects of PEITC on Oral Cells With Mutant p53
The aim of this clinical trial is to examine the effects of phenethyl isothiocyanate (PEITC), a compound derived from cruciferous vegetables, on oral cells with mutant p53.
- Trial name
- NCT01790204
- Testing
- Watercress Juice
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Georgetown University
Chronic Lymphocytic Leukemia, Non-Hodgkin's Lymphoma
Trial of Bendamustine, Lenalidomide and Rituximab in Chronic Lymphocytic Leukemia (CLL) and Non-Hodgkin's Lymphoma (NHL)
This study is for subjects with a B-cell lymphoid malignancy (lymphoma) or chronic lymphocytic leukemia (CLL) that has come back after or did not get better with previous treatment.
- Trial name
- Phase I BLR (NCT00864942)
- Testing
- bendamustine and lenalidomide, BL-NHL, BLR-CLL
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Georgetown University