Clinical trials: sponsored by Georgetown University
Prostate Cancer, Localized Malignant Neoplasm
Quality of Life in Patients With Clinically Localized Prostate Cancer Treated With Radiosurgery
Quality of life data following SBRT for prostate cancer has been obtained in only a small numbers of patients. A prospective study using validated quality of life questionnaires is needed to determine outcomes after treatment…
- Trial name
- PR-PROS (NCT01766492)
- Testing
- Stereotactic Body Radiation Therapy (SBRT)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Georgetown University
Prostate Cancer
Phase II Study to Evaluate Conventional Radiation Therapy Followed by Radiosurgical Boost in Clinically Localized Prostate Cancer
This phase II study designed to prospectively evaluate the efficacy and morbidity of IMRT with CyberKnife radiosurgical boosts for clinically localized prostate cancer.
- Trial name
- NCT01618851
- Testing
- Radiotherapy with IMRT and CyberKnife Boost
- Volunteers
- 70 people
- Sponsor
- Georgetown University
Antibiotic-associated Diarrhea
Mechanisms of Preventing Antibiotic-Associated Diarrhea and the Role for Probiotics
The focus of the study is to better understand the mechanisms causing antibiotic-associated diarrhea (AAD) and how probiotics may prevent some of the iatrogenic effects of antibiotic medications.
- Trial name
- YOBIOTIC (NCT03755765)
- Testing
- Amoxicillin-Clavulanate 875 Mg-125 Mg Oral Tablet, BB-12, Control
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Thymoma, Advanced Thymic Epithelial Tumor
Selinexor in Patients With Advanced Thymic Epithelial Tumor Progressing After Primary Chemotherapy
The purpose of this study is to evaluate the safety, tolerability and effectiveness of selinexor in patients with advanced thymic epithelial tumor progressing after primary chemotherapy.
- Trial name
- SELECT (NCT03193437)
- Testing
- Open Label Selinexor
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Georgetown University
Hookah Tobacco Smoking
Optimizing Hookah Tobacco Public Education Messages to Reduce Young Adult Use
This is a 2-arm randomized controlled trial to test the effects of hookah tobacco public education messages among young adults who are susceptible non-users of hookah tobacco and those who are current hookah tobacco users.
- Trial name
- NCT04252014
- Testing
- Hookah tobacco messages
- Where
- United States
- Volunteers
- 830 people
- Sponsor
- Georgetown University
Anxiety Disorders, Generalized Anxiety Disorder
Effect of Mindfulness Meditation on Physiological Response to Unpredictable Stimuli
This study will evaluate the effects of Mindfulness-Based Stress Reduction (MBSR) on physiological reactivity. This study will focus on individuals with anxiety who will participate in an 8-week MBSR class.
- Conditions
- Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT03206437
- Testing
- Mindfulness-Based Stress Reduction, Waitlist
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Georgetown University
Breast Cancer, Ovarian Cancer
Decision Support Following Genetic Testing for Breast-Ovarian Cancer Susceptibility
This non-therapeutic trial is for women who have received results of genetic testing for BRCA1/2 mutations. The trial compares decision support tools designed to facilitate informed decision making regarding risk management…
- Trial name
- NCT02133703
- Testing
- Enhanced Internet DA, Internet DA, Enhanced Print DA
- Where
- United States
- Volunteers
- 369 people
- Sponsor
- Georgetown University
Nonalcoholic Steatohepatitis
Safety and Tolerability of Oral Proglumide for NASH
This study is an open labelled Phase I/II clinical trial, designed to evaluate the safety and efficacy of an oral cholecystokinin (CCK) receptor antagonist, proglumide, at escalating doses in subjects with NASH.
- Trial name
- STOPNASH (NCT04152473)
- Testing
- Proglumide
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Georgetown University
Lung Cancer
Educating Providers About Lung Screening
We are conducting a randomized trial to compare the Health Disparities module to an existing provider module on lung cancer screening to evaluate the impact on primary care providers' knowledge, attitudes, and lung cancer…
- Trial name
- NCT05064046
- Testing
- LuCa + Health Disparity module
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Indoor Tanning
A Mobile Text Messaging Intervention for Indoor Tanning Addiction
The purpose of this study is to test the effects of messages communicating the risks (i.e., health harms, addictiveness) of indoor tanning delivered via mobile text messaging among young adult women ages 18 to 30 years who meet…
- Trial name
- NCT04055272
- Testing
- Mobile text messaging intervention
- Where
- United States
- Volunteers
- 265 people
- Sponsor
- Georgetown University
Stress Disorders, Post-Traumatic
A Cognitive Behavioral Therapy and Yoga Program for Trauma Symptoms
The purpose of the proposed study is to evaluate the effectiveness of a cognitive behavioral therapy (CBT) and yoga program for improving posttraumatic stress disorder (PTSD) symptoms and sleep quality in people who have…
- Trial name
- NCT02368444
- Testing
- Cognitive Behavioral Therapy and Yoga
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Wound Infection
Investigation of a Novel Wound Gel to Improve Wound Healing in Chronic Wounds
This is a prospective, randomized, double-blinded, single site study examining the impact of a biofilm-based treatment of chronic wounds of the lower extremity. 200 subjects will be enrolled in this study.
- Trial name
- NCT03686904
- Testing
- Benzalkonium Gel, standard of care topical gel, Debridement
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Georgetown University
Hereditary Breast and Ovarian Cancer Syndrome
Enhance the Use of Genetic Counseling and Testing in Latinas
The investigators will conduct a two-arm RCT to evaluate the preliminary effectiveness of a culturally-adapted video developed by the team vs.
- Trial name
- NCT04544501
- Testing
- Culturally-Targeted Video, FORCE Fact Sheet
- Where
- 4 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Hereditary Breast and Ovarian Cancer
Testing an Intelligent Tutoring System to Enhance Genetic Risk Assessment
Participating in genetic cancer risk assessments (GCRA) for hereditary breast and ovarian cancer can inform treatment and risk management decisions and improve breast cancer outcomes.
- Trial name
- NCT03511690
- Testing
- BRCA-Gist
- Where
- 4 sites in United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Cirrhosis, Liver
Single-dose PK Assessment of Oral Proglumide in Those With Hepatic Impairment
Proglumide is an oral cholecystokinin (CCK) receptor antagonist that has been shown in non-clinical studies to reverse hepatic fibrosis and decrease the incidence of hepatocellular carcinoma (HCC).
- Trial name
- HIPK (NCT04814602)
- Testing
- Proglumide
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Anxiety Disorders, Generalized Anxiety Disorder
Treatments for Anxiety: Meditation and Escitalopram
We propose the first randomized, controlled study to assess the comparative effectiveness of Mindfulness-Based Stress Reduction (MBSR) with a medication for anxiety disorders.
- Conditions
- Anxiety Disorders, Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder
- Trial name
- TAME (NCT03522844)
- Testing
- Mindfulness-Based Stress Reduction, Escitalopram
- Where
- 3 sites in United States
- Volunteers
- 276 people
- Sponsor
- Georgetown University
Tobacco Use
Effect of Cigarette Pack Warnings and Packaging Among Young Adult Smokers
The objective of this study is to examine whether cigarette packaging regulations including graphic health warning labels on cigarette packs and requiring plain, unbranded packaging reduce the appeal of cigarettes and prompt…
- Trial name
- NCT03446170
- Testing
- Graphic cigarette warning labels, plain packaging
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Georgetown University
Hookah Smoking
Optimizing Risk Messages for Waterpipe Tobacco Cessation in Young Adults
The objective of this study is to examine whether messages conveying the harms and addictiveness of waterpipe (i.e., hookah) tobacco delivered by mobile phone multimedia messaging (MMS) are effective for promoting hookah tobacco…
- Trial name
- NCT03595280
- Testing
- Hookah tobacco risk messages
- Where
- 2 sites in United States
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Type 1 Diabetes, Children, Only
Pediatric Boot Camp Program
An intensive 13 weeks program that aims to improve glucose control in children with type 1 diabetes.
- Trial name
- NCT05066893
- Testing
- telehealth visits
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Georgetown University
Hormone Receptor Positive HER-2 Negative Breast Cancer
Palbociclib / Letrozole or Fulvestrant in African American Women With HR+ HER2- Breast Cancer
This study aims to evaluate the hematological safety of palbociclib with letrozole and fulvestrant in African American women with hormone receptor positive HER2 negative advanced breast cancer.
- Trial name
- PALINA (NCT02692755)
- Testing
- Palbociclib + Letrozole or Fulvestrant
- Where
- 6 sites in United States
- Volunteers
- 35 people
- Sponsor
- Georgetown University