Clinical trials: sponsored by Georgetown University
Breast Cancer, Hereditary Breast Cancer
Testing a Culturally Adapted Telephone Genetic Counseling Intervention
Participating in genetic cancer risk assessments (GCRA) for hereditary breast and ovarian cancer (HBOC) can inform treatment and risk management decisions and improve breast cancer outcomes.
- Trial name
- NCT03959267
- Testing
- Telephone Genetic Counseling
- Where
- 4 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Social Behavior
Metta Meditation Training on Prosocial Behavior
The purpose of the study is to look at the impact of a metta meditation training on prosocial behavior and socio-affective brain responses.
- Trial name
- NCT03894930
- Testing
- Metta meditation
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Meditation
Online Trial of Meditation and Behavior
This study investigates how different types of meditation may affect behaviors and emotions. The study is conducted entirely online and involves listening to 4-weeks of a guided meditation training.
- Trial name
- NCT04632875
- Testing
- Loving-Kindness Meditation, Relaxation Meditation
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Small Cell Lung Cancer, Small Cell Lung Cancer Extensive Stage
Nivolumab and 177Lu-DOTA0-Tyr3-Octreotate for Patients With Extensive-Stage Small Cell Lung Cancer
This research study is being done to assess the safety and tolerability of study drugs, 177Lu-DOTA0-Tyr3-Octreotate (Lutathera) and nivolumab in subjects with small cell lung cancer or advanced or inoperable neuroendocrine tumor…
- Trial name
- NCT03325816
- Testing
- Nivolumab, 177Lu-DOTA0-Tyr3-Octreotate
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Georgetown University
Breast Cancer
Acupressure for Cancer-Related Fatigue
This study develops and pilot tests the efficacy of a home-based, self-administered acupressure intervention in improving cancer-related fatigue (proximal outcome), and physical functioning and other quality of life outcomes…
- Trial name
- NCT03091647
- Testing
- acupressure intervention, usual care
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Georgetown University
Breast Cancer
Web-Based Communication Education for Breast Cancer Survivorship Care
This two-phase research plan will develop and test a culturally relevant, web-based patient education program, hereafter known as E-Talkcare.
- Trial name
- NCT03413332
- Testing
- E-Talkcare, Usual Care
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Georgetown University
Breast Cancer, Mastectomy; Lymphedema
Same-Day Discharge After Nipple-sparing Mastectomy or Skin-sparing Mastectomy With Breast Reconstruction
This novel study will assess the feasibility and outcomes of same-day discharge following mastectomy with implant-based pre-pectoral reconstruction.
- Conditions
- Breast Cancer, Mastectomy; Lymphedema, Same Day Surgery, Nipple-sparing Mastectomy
- Trial name
- NCT04596683
- Testing
- Same-day NSM or SSM
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Georgetown University
Post-operative Pain, Post-operative Nausea and Vomiting
Multimodal Perioperative Pain Management: ComfortSafe Program
Proposed is a demonstration project to characterize the immediate, short-term and long-term pain and other post-operative outcomes of 60, self-selected breast (n=20), caesarian-section (n=20) and abdominal (n=20) surgical…
- Conditions
- Post-operative Pain, Post-operative Nausea and Vomiting, Respiratory Depression, Confusion Postoperative
- Trial name
- NCT04046068
- Testing
- ComfortSafe Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Georgetown University
Wounds and Injuries
Bacterial Load for Integra™ in Operative Wounds
Proportion of postoperative complications (infections, dehiscence, graft slough) after initial application of Integra™
- Trial name
- NCT04543240
- Testing
- Integra™ dermal regeneration template
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Georgetown University
Diabetes Mellitus
Evaluating the Effects of Kombucha as a Hyperglycemic Therapeutic Agent Within Diabetic Human Subjects
This study's primary objective is to determine the ability of Kombucha to impact blood sugar levels in patients with diabetes mellitus type II.
- Trial name
- NCT04107207
- Testing
- Ginger Kombucha, Ginger Water
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Mastectomy, Breast Cancer
Post-Mastectomy Analgesia Using Exparel (Liposomal) Versus Standard Bupivacaine or Placebo
This is a randomized, single-blinded placebo-controlled trial. Patients will be randomized to one of three arms: (1) injection of liposomal bupivacaine at the end of the operation, (2) injection of standard bupivacaine at the end…
- Trial name
- NCT03504865
- Testing
- Liposomal bupivacaine, Standard bupivacaine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Georgetown University
Stroke
Stroke Transitions of Care to Reduce Hospital Length of Stay
The purpose of this prospective pilot study is to access the feasibility of Transitions of Care Coordinator (TOCC) program, to determine if the use of a TOCC will decrease hospital length of stay (LOS), and determine if…
- Trial name
- TOCC (NCT04434638)
- Testing
- Transitions of Care Coordinator, Usual Care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Georgetown University
Ischemic Stroke, Hypertension
Home Blood Pressure Study for Recent Stroke Survivors With High Blood Pressure *On Hold Due to Global Pandemic*
The purpose of this pilot study is to assess the feasibility of implementing a home blood pressure self-management program in a population of recent stroke survivors in the Washington, D.C. area.
- Trial name
- HBPS (NCT04226157)
- Testing
- Home Blood Pressure Monitoring Device (Qardio Arm), Primary Care Provider Blood Pressure Management
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- MedStar Georgetown University Hospital
Renal Transplant Recipients
Envarsus XR in African American Renal Transplant Recipients
The purpose of this study is to collect data prospectively on African American patients who are taking the immunosuppressant Envarsus post kidney transplant.
- Trial name
- EXR (NCT02956005)
- Testing
- ENVARSUS®
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Georgetown University
Chronic Venous Hypertension With Ulcer
ActiV.A.C.+ Compression Therapy Versus Compression Therapy Alone for the Treatment of Chronic Venous Ulcerations
This is a prospective, randomized, comparative interventional human subject trial. Patients with a chronic venous ulceration of the lower extremity will be enrolled into this study.
- Trial name
- NCT01528293
- Testing
- ActiVAC System, Compression therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Georgetown University
Colorectal Cancer
Panitumumab and Bortezomib for Patients With Advanced Colorectal Cancer
Panitumumab plus bortezomib for colon cancer
- Trial name
- NCT01504477
- Testing
- Panitumumab and bortezomib
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Georgetown University
Peripheral Vascular Disease
Pilot Study to Determine Percent Tissue Perfusion and Cellular Viability Using SPY Imaging
Little is known about chronic wound microenvironments, especially in peripheral vascular disease (PVD) and diabetic patients. At the demarcation line, the percentage of viable cells and tissue is unclear.
- Trial name
- NCT01522495
- Testing
- SPY Imaging, ICG dye (0.2 - 0.5 mg/kg), SPY Imaging
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Georgetown University
Wounds, Chronic Wounds
Comparing the Clinical Outcomes of DermACELL® With Integra® Bilayer Wound Matrix
Both DermACELL® and Integra® Bilayer Wound Matrix are indicated for deep soft tissue coverage and serve as a biological matrix for cellular migration.
- Conditions
- Wounds, Chronic Wounds, Nonmalignant Condition
- Trial name
- NCT03285698
- Testing
- DermACELL®, Integra®
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Georgetown University
Advanced Solid Tumor Malignancies
PD-0332991, 5-FU, and Oxaliplatin for Advanced Solid Tumor Malignancies
This study is for patients with advanced solid tumor malignancies (cancer that has spread to other parts of the body). The purpose of this study is to test the safety and effectiveness of a new combination of drugs, PD-0332991…
- Trial name
- NCT01522989
- Testing
- PD-0332991, 5-FU, Oxaliplatin
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Georgetown University
Huntington Disease
Nilotinib in Huntington's Disease
Based on strong pre-clinical evidence of the effects of Nilotinib on neurodegenerative pathologies, including autophagic clearance of neurotoxic proteins, neurotransmitters (dopamine and glutamate), immunity and behavior, the…
- Trial name
- Tasigna HD (NCT03764215)
- Testing
- Nilotinib 150 MG
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Georgetown University