Clinical trials: sponsored by Georgetown University
Desire to Avoid Pregnancy
Effectiveness and Efficacy of Dynamic Optimal Timing, a Smart Phone App for Avoiding Pregnancy: an Observational Study
The purpose of this study is to assess the effectiveness and efficacy of Dynamic Optimal Timing (DOT), an app-based method of family planning that can be used via Android devices, for women who use the method to avoid pregnancy.
- Trial name
- NCT02833922
- Testing
- Women using Dot to avoid pregnancy
- Volunteers
- 718 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Breast Cancer, Obesity
Exergaming Intervention and Breast Cancer Biomarkers in Black Women
Overview: This is a 6 month, two-arm randomized clinical trial using comparing exergaming to a control group. The investigators will randomize Black sedentary overweight/obese women to Wii Fit exercise (n=50) or the control arm…
- Trial name
- POWER (NCT02152462)
- Testing
- Exergaming
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Proteinuria
A Crossover Pilot Study of the Effect of Amiloride on Proteinuria
This cross-over study is designed to test the hypothesis that amiloride will reduce urinary protein excretion and protect the kidney from rapid progression in proteinuric kidney disease.
- Trial name
- NCT02522650
- Testing
- Amiloride, Triamterene
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Georgetown University
Parental Infant Bonding, Cardio-respiratory Stability in Preterm NICU Infants
Effects of Reading to Preterm Infants on Baby and Parents' Well Being
Reading to children is believed to be beneficial to cognitive and mental development.This study will examine the response of premature Neonatal Intensive Care Unit (NICU) infants to bedside reading by measuring changes in heart…
- Trial name
- NCT02518997
- Testing
- Parental Reading Aloud
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Georgetown University
Breast Cancer
Effects of a Structured Exercise Program on Cancer-Related Fatigue in Women Receiving Radiation Therapy for Breast Cancer
Radiation therapy (RT) is often used to treat breast cancer. RT combined with breast surgery is associated with better outcomes in early stage breast cancer compared to surgery alone.
- Trial name
- NCT02117011
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Georgetown University
Thymic Carcinoma, Thymus Neoplasms
Pembrolizumab and Epacadostat in Patients With Thymic Carcinoma
This is a non-randomized clinical trial in patients with thymic carcinomas who failed prior systemic therapy. All subjects will receive pembrolizumab and epacadostat treatment in three week cycles until unacceptable toxicity…
- Conditions
- Thymic Carcinoma, Thymus Neoplasms, Thymus Cancer
- Trial name
- NCT02364076
- Testing
- Pembrolizumab, Epacadostat
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Georgetown University
Hereditary Breast and Ovarian Cancer
Enhancing At-risk Latina Women's Use of Genetic Counseling for Hereditary Breast and Ovarian Cancer
Compared to non-Latina Whites, Latinas have a higher prevalence of BRCA1/2 gene mutations but lower use of genetic cancer risk assessments services (GCRA).
- Trial name
- NCT03075540
- Testing
- Genetic Counseling and Testing YouTube Video
- Where
- 2 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Alzheimer Disease, Dementia
DC Longitudinal Study on Aging and Specimen Bank
The Georgetown University Memory Disorders Program, part of the Department of Neurology, is conducting pilot studies of the feasibility of various diagnostic tests for Alzheimer's disease, mild cognitive impairment and other…
- Conditions
- Alzheimer Disease, Dementia, Mild Cognitive Impairment, Aging
- Trial name
- (DC LSOA) (NCT03702907)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Surgical Wound, Wound Heal
Evaluating the Outcomes for Incisional Application of Negative Pressure for Nontraumatic Amputations
The purpose of this study is to evaluate how well subjects heal after surgery who receive standard dressings or incisional negative pressure wound therapy for non-traumatic amputation sites.
- Conditions
- Surgical Wound, Wound Heal, Amputation
- Trial name
- NCT03250442
- Testing
- PrevenaTM Device, Standard Dry Dressing
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Wound Infection
Outcomes for 2 Operations Versus ≥ 3 Operations in Infected Wounds
We have designed this study to determine whether performing two, compared with ≥3 operations has an effect on key clinical outcomes after discharge from the hospital of an infected wound that requires admission.
- Trial name
- NCT02559453
- Testing
- Debridement
- Volunteers
- 250 people
- Sponsor
- Georgetown University
Diabetic Foot Ulcers, Equinus Deformity
Determination of the Pathophysicologic Collagen Changes in the Diabetic Achilles Tendon
This is a pilot study examining tendon collagen, collagen cross-linking, and markers of tendon extracellular matrix metabolism in the Achilles tendon of diabetic patients with ulcerations and amputations of the lower extremity.
- Trial name
- NCT01382628
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Georgetown University
Gulf War Illness
"Immunomodulation in GWI (Phlebotomy)"
Gulf War Illness and deployed veterans of the 1990-1991 Persian Gulf War are invited to have a brief history and physical examination to determine their health status, complete questionnaires, then donate about 83 ml of blood.
- Trial name
- NCT04058275
- Testing
- Draw blood (phlebotomy, 83 ml)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Gulf War Illness, Persian Gulf Syndrome
Exercise in Gulf War Illness (GWI)
The purpose of this study is to determine if submaximal exercise by bicycle stress tests with pulmonary measurement of VO2MAX plus maximal isometric hand grips on 2 consecutive days causes a higher level of "exertional…
- Trial name
- NCT01291758
- Testing
- Submaximal bicycle exercise stress tests performed 24 hr apart
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Breast Cancer
A Multi-Institutional Registry for CyberKnife Stereotactic Accelerated Partial Breast Irradiation (CK-SAPBI)
This study is a registry to monitor quality of life and clinical outcomes in patients with clinically localized breast cancer who have received stereotactic accelerated partial breast irradiation via CyberKnife.
- Trial name
- NCT02457117
- Testing
- CyberKnife Stereotactic Accelerated Partial Breast Irradiation (CK-SAPBI)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Georgetown University
Respiratory Tract Infections
Measuring the Influence of Kefir on Children's Stools on Antibiotics (MILK)
The purpose of this study is to determine the effectiveness of commercially available kefir on preventing antibiotic-associated diarrhea compared to placebo in children ages 1-5.
- Trial name
- MILK (NCT00481507)
- Testing
- Kefir
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Persian Gulf Syndrome
Treatment Study of Carnosine Versus Placebo in Gulf War Illness (GWI)
The purpose of this study is to perform a randomized double-blind, placebo-controlled, 12 week study of the effects of carnosine on cognitive, psychometric, autonomic, and muscle strength outcomes in 100 GWI subjects.
- Trial name
- NCT00810368
- Testing
- Carnosine
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Georgetown University
Chronic Fatigue Syndrome
Exertional Exhaustion in Chronic Fatigue Syndrome
Post-exertional malaise was modeled by having Chronic Fatigue Syndrome (CFS) and sedentary control subjects perform submaximal exercise on 2 consecutive days with objective changes in brain function measured by magnetic resonance…
- Trial name
- NCT03567811
- Testing
- Submaximal bicycle exercise stress test on Days 1 and 2
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Gulf War Syndrome
START & STOPP in GWI
Gulf War Illness (GWI) veterans were divided into 2 pathophysiological groups based on their orthostatic tachycardia responses after submaximal exercise.
- Trial name
- START (NCT03560830)
- Testing
- 2 submaximal exercise stress tests
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Breast Cancer Female
Predictors of Adjuvant Endocrine Therapy in Women With Breast Cancer
Breast cancer is the leading cancer diagnosed in women and the second cause of cancer death. Of all racial/ethnic groups in the US, Black women have the highest rate of breast cancer deaths.
- Trial name
- WHIP (NCT02992730)
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Quality of Life, Breast Cancer
Nueva Vida Intervention for Latina Breast Cancer Survivors and Caregivers
Latina breast cancer survivors report lower quality of life (QOL) than non-Latina survivors. Lower QOL can lead to poorer functional and cancer-related survival outcomes.
- Trial name
- NCT02222337
- Testing
- Nueva Vida Intervention
- Where
- 4 sites in United States
- Volunteers
- 272 people
- Sponsor
- Georgetown University