Clinical trials: sponsored by HK inno.N Corporation
Gastroesophageal Reflux Disease
A Study to Evaluate the Efficacy and Safety of Tegoprazan in GERD Patients With Nighttime Heartburn
This study aims to compare the nighttime heartburn improvement effect of Tegoprazan 50mg and Esomeprazole 40mg(or 20mg) in patients with GERD.
- Trial name
- NCT05701540
- Testing
- Tegoprazan, Esomeprazole
- Where
- South Korea
- Volunteers
- 338 people
- Sponsor
- HK inno.N Corporation
Helicobacter Pylori Infection
Exploratory Study to Standard Triple Therapy With Tegoprazan(by Dose) in H. Pylori Positive Patients
This exploratory study is designed to compare safety and efficacy between a Tegoprazan dose-specific standard triple therapy and Lansoprazole standard triple therapy in H. pylori positive patients.
- Trial name
- NCT05933031
- Testing
- Tegoprazan 50 mg Triple Therapy, Tegoprazan 100 mg Triple Therapy, Lansoprazole Triple Therapy
- Where
- South Korea
- Volunteers
- 381 people
- Sponsor
- HK inno.N Corporation
Essential Hypertension
A Study to Evaluate the Efficacy and Safety of Amlodipine Besylate and Candesartan Cilexetil in Essential Hypertension Patient Who Are Not Adequately Controlled With Amlodipine Besylate Monotherapy
Compare the safety and efficacy of amlodipine besylate and candesartan cilexetil combination therapy on patients of essential hypertension who are not properly controlled by amlodipine besylate monotherapy.
- Trial name
- NCT02368665
- Testing
- Amlodipine 5mg, Amlodipine 5mg, Candesartan cilexetil 16mg, Amlodipine 10mg, Candesartan cilexetil 16mg
- Where
- 19 sites in South Korea
- Volunteers
- 180 people
- Sponsor
- HK inno.N Corporation
Essential Hypertension
A Study to Evaluate the Efficacy and Safety of Amlodipine Besylate and Candesartan Cilexetil in Essential Hypertension Patient Who Are Not Adequately Controlled With Candesartan Cilexetil Monotherapy
Compare the safety and efficacy of amlodipine besylate and candesartan cilexetil combination therapy on patients of essential hypertension who are not properly controlled by candesartan cilexetil monotherapy.
- Trial name
- NCT02368652
- Testing
- Candesartan cilexetil 16mg, Amlodipine 10mg, Candesartan cilexetil 16mg
- Where
- 19 sites in South Korea
- Volunteers
- 181 people
- Sponsor
- HK inno.N Corporation
Healed Erosive Esophagitis
Study to Confirm the Safety and Efficacy of Tegoprazan in Patients With Healed Erosive Esophagitis
This study is designed to confirm the non-inferiority of Tegoprazan 25mg, compared to Lansoprazole 15mg as maintenance therapy in patients with healed erosive esophagitis confirmed by endoscopy following oral administration once…
- Trial name
- NCT04022096
- Testing
- Tegoprazan 25mg QD, Lansoprazole 15mg QD
- Where
- South Korea
- Volunteers
- 351 people
- Sponsor
- HK inno.N Corporation
Erosive Reflux Disease
Study to Confirm the Safety and Efficacy of Tegoprazan in Patients With Healed Erosive Reflux Disease
This study is designed to evaluate the efficacy and safety of Tegoprazan 50mg, compared to Lansoprazole 30mg in patients with healed erosive reflux disease confirmed by endoscopy following oral administration once daily(QD) of 2…
- Trial name
- NCT05267743
- Testing
- Tegoprazan 50mg QD, Lansoprazole 30mg QD
- Where
- South Korea
- Volunteers
- 218 people
- Sponsor
- HK inno.N Corporation
Healthy
Evaluation of the Pharmacokinetics/Pharmacodynamics and Safety/Tolerability of IN-C005 and IN-A001 in Healthy Caucasians
The purpose of this study is to evaluate pharmacokinetics/pharmacodynamics and safety/tolerability of IN-C005 and IN-A001 after oral administration in healthy Caucasian subjects.
- Trial name
- NCT05005065
- Testing
- IN-C005 X mg, IN-A001 Y mg, IN-C005 Y mg
- Where
- 2 sites in South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Hypertension, Hyperlipidemia
Evaluate Efficacy and Safety of Ezetimibe/Rosuvastatin and Candesartan Cilexetil/Amlodipine Besylate Combination Tablets
To evaluate the efficacy and the safety of concomitant use of Ezetimibe/Rosuvastatin combination tablets and Candesartan cilexetil/Amlodipine besylate combination tablets compared to each combination tablet alone in patients with…
- Trial name
- REVERT-K (NCT03847506)
- Testing
- Ezetimibe/Rosuvastatin, Candesartan cilexetil/Amlodipine besylate, Candesartan cilexetil
- Where
- South Korea
- Volunteers
- 127 people
- Sponsor
- HK inno.N Corporation
Healthy
A Study to Evaluate Effect of IN-A001 on Pharmacokinetics of Tacrolimus in Healthy Volunteers
This study aims to investigate the effect of IN-A001 50mg on the pharmacokinetics of Tacrolimus 5mg in healthy volunteers
- Trial name
- NCT05353010
- Testing
- Tacrolimus, IN-A001(Tegoprazan), IN-A001(Tegoprazan) + Tacrolimus
- Where
- South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Hypertension
A Bioequivalence Study Between Telmione 80 mg and Micardis 80 mg in Healthy Adult Volunteers
To compare the pharmacokinetics and safety after a single dose administration of Telmione® 80 mg and Micardis® 80 mg in healthy adult volunteers
- Trial name
- NCT05223101
- Testing
- Telminone 80 mg, Drug: Micardis 80 mg
- Where
- South Korea
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Erosive Reflux Disease
Study to Evaluate the Efficacy and Safety of Tegoprazan in ERD Patients With Nighttime Heartburn and Sleep Disturbance
This study aims to compare the nighttime heartburn and sleep disturbance improvement effect of Tegoprazan 50mg and Eomeprazole 40mg in patients with ERD patients.
- Trial name
- NCT04309916
- Testing
- Tegoprazan, Esomeprazole
- Where
- South Korea
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Hypertension
A Bioequivalence Study Between Telmione Plus 80/12.5mg and Micardis Plus 80/12.5 mg in Healthy Adult Volunteers
To compare the pharmacokinetics and safety after a single dose administration of Telmione plus® 80/12.5mg and Micardis plus® 80/12.5mg in healthy adult volunteers
- Trial name
- NCT05040880
- Testing
- Telmione plus 80/12.5mg, Micardis plus 80/12.5mg
- Where
- South Korea
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
COVID-19
Study to Evaluate the Safety and Immunogenicity of SARS-CoV-2 Vaccine (IN-B009) in Healthy Adults (COVID-19)
This is a first in human, phase I, open-label, dose-escalation study to assess the safety, reactogenicity, and immunogenicity of a SARS-CoV-2 Vaccine (IN-B009) in healthy adults.
- Trial name
- NCT05113849
- Testing
- IN-B009 (Low-dose), IN-B009 (High-dose)
- Where
- 3 sites in South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Helicobacter Pylori Infection
A Phase 3 Study to Evaluate the Efficacy and Safety of Triple Therapy With CJ-12420 in H. Pylori Positive Patients
The current study is designed to demonstrate the non-inferiority of CJ-12420-based triple therapy (CJ-12420, amoxicillin and clarithromycin) versus lansoprazole-based triple therapy (lansoprazole, amoxicillin and clarithromycin)…
- Trial name
- NCT03317223
- Testing
- CJ-12420/Clarithromycin/Amoxicillin
- Where
- South Korea
- Volunteers
- 350 people
- Sponsor
- HK inno.N Corporation
Healthy
A Study to Investigate the Effect of Food on the Pharmacokinetics of IN-A002 Capsule in Healthy Male Subjects
This study aims to investigate the effect of food on the pharmacokinetics of IN-A002 capsule in healthy male subjects
- Trial name
- NCT05019755
- Testing
- IN-A002(IN-115314) capsule
- Where
- South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Healthy
Bioequivalence and Safety Study of IN-A012 and Akynzeo Capsules in Male and Female Healthy Korean Subjects
The main purpose of this study is to demonstrate the bioequivalence between IN-A012 and Akynzeo capsules by pharmacokinetic(PK) evaluation
- Trial name
- NCT04486157
- Testing
- IN-A012, Akynzeo 300Mg-0.5Mg Capsule
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Helicobacter Pylori Infection
Triple Therapy With Tegoprazan in H. Pylori Positive Patients_PILOT
This study aims to compare safety and efficacy in an exploratory manner between a Tegoprazan triple therapy and a RAPAE01 triple therapy in H. pylori positive patients.
- Trial name
- NCT04128917
- Testing
- Tegoprazan, RAPAE01
- Where
- South Korea
- Volunteers
- 102 people
- Sponsor
- HK inno.N Corporation
Healthy
Study to Evaluate the Pharmacokinetic Characteristics and Safety of IN-C004 in Healthy Volunteers
To evaluate the pharmacokinetic characteristics and safety of IN-C004 in healthy volunteers
- Trial name
- NCT04654078
- Testing
- IN-C004 with water, IN-C004 without water, K-CAB tab. with water
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Healthy
Study to Evaluate Oral Mucosa Absorption of IN-C004 in Healthy Volunteers
To evaluate whether IN-C004 absorbs oral mucosa in healthy volunteers.
- Trial name
- NCT04654065
- Testing
- IN-C004
- Where
- South Korea
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Healthy
A Study to Explore Pharmacokinetics/Pharmacodynamics and Safety of Tegoprazan BID Dosing in Healthy Subjects
The main purpose of this study is to explore the pharmacokinetics, pharmacodynamics and safety after twice-daily dosing of tegoprazan tablets in healthy subjects.
- Trial name
- NCT04587011
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation