Clinical trials: sponsored by IRCCS Eugenio Medea
Sotos Syndrome, Beckwith-Wiedemann Syndrome
Body Perception and Representation in Overgrowth Syndromes, Behavioral Assessment and Neuropsychological Development
Sotos Syndrome (SS) and Beckwith-Wiedemann Syndrome (BWS) are known as overgrowth syndromes as they involve an excessive growth of the whole body or of specific body parts.
- Conditions
- Sotos Syndrome, Beckwith-Wiedemann Syndrome, Overgrowth Syndrome, Body Image
- Trial name
- Body-PROBAND (NCT04993235)
- Testing
- NEPSY-II, CBCL and AQ questionnaires, BUT questionnaire and experimental tasks
- Where
- Italy
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Developmental Disability, Parent Child Relationship
Mother-Infant Interaction Kinect Analysis (MIIKA)
An innovative methodology is developed to better understand parent-infant relationships. RGB-D sensors (such as Microsoft Kinect) give us the opportunity of online skeleton extraction based on the joints architecture of human…
- Trial name
- MIIKA (NCT04288973)
- Testing
- Microsoft Kinect Detection during mother child interaction
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- IRCCS Eugenio Medea
Autism Spectrum Disorder
EMPATIA@Lecco- Balance Rehabilitation of Autistic Children With Virtual rEality
The general objective of this project is to investigate the possible efficacy of a training based on proprioceptive and visual feedback carried out with the GRAIL (Motekforce Link) virtual reality environment on postural control…
- Trial name
- BRAVE (NCT04276571)
- Testing
- exergames with GRAIL virtual immersive reality environment
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- IRCCS Eugenio Medea
Dyslexia
VAlidation of an Educational Technological Tool for Dyslexic Adolescents: an Open Controlled Study
Virtual reality (VR) and augmented reality (AR) are gaining importance in the rehabilitation programs for learning disabilities.
- Trial name
- FORDYS (NCT05028647)
- Testing
- Virtual reality training, Augmented reality training
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Eugenio Medea
Acquired Brain Injury
Experimentation of an Ankle Mobilization Device for the Rehabilitation of Patients With Acquired Brain Injuries.
The proposed clinical investigation plan is a randomized controlled pivotal study with 2 parallel groups, has a total duration of two years.
- Trial name
- NCT03879070
- Testing
- Ankle active and passive mobilization using an Ankle mobilization device
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Eugenio Medea
Acquired Brain Injury
Experimentation of Sensorized Pseudoelastic Orthoses Produced by Additive Manufacturing
The proposed clinical investigation plan is a pivotal controlled study with two parallel groups, has a total duration of 12 months and involves the recruitment of 34 pediatric patients suffering from acquired brain injury.
- Trial name
- NCT04328857
- Testing
- pseudoelastic orthosis
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- IRCCS Eugenio Medea
Rett Syndrome
Tolerability of the Immersive Virtual Reality System Grail in Subjects Affected by Rett Syndrome
The main goal of this study is to investigate the tolerability to the use of the GRAIL system in subjects affected by Rett syndrome, particularly referred to: 1.
- Trial name
- NCT05691582
- Testing
- GRAIL
- Where
- Italy
- Volunteers
- 9 people
- Sponsor
- IRCCS Eugenio Medea
Cerebral Palsy
Study of Navigation Skills in Cerebral Palsy for Assessment and Rehabilitation in Immersive Virtual Reality
Spatial navigation refers to the ability to maintain a sense of direction/location while moving around the environment so to find one's way.
- Trial name
- NCT04270305
- Testing
- Orientation, walking
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Attention Deficit Hyperactivity Disorder
Multi Neuro-functional Biomarkers for Monitoring the Effects of Treatments in ADHD Children
MIMOSA study aims to characterize from behavioral, neurophysiological and neurocognitive perspectives children and adolescents with attention deficit hyperactivity disorder (ADHD), in order to identify a possible biomarker of…
- Trial name
- MIMOSA (NCT04272021)
- Testing
- Methylphenidate
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Eugenio Medea
Dyslexia, Developmental
Neurofunctional Correlates of the Behavioral Modifications Associated With Tachidino in Children With Developmental Dyslexia
Developmental dyslexia (DD) is the most common learning disorder. Multiple cognitive and sensory domains contribute to the etiology of DD and develop before reading acquisition.
- Trial name
- TACHIDINO (NCT05373576)
- Testing
- TACHIDINO
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Eugenio Medea
Adolescent Idiopathic Scoliosis, Osteogenesis Imperfecta
Experimental Evaluation of Back Braces for the Treatment of Spinal Deformity Produced With 3D Printing Technology
The proposed investigation is a pilot study that involves pediatric patients affected by spinal deformity (Adolescent Idiopathic Scoliosis and Osteogenesis Imperfecta).
- Trial name
- NCT04282408
- Testing
- Scoliosis back brace
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- IRCCS Eugenio Medea
Neurodevelopmental Disorders
A Multi-domain Approach for the Characterization and Early Diagnosis of Neurodevelopmental Disorders
Diagnosis and characterization of neurodevelopmental disorders are considered challenging processes because of their complexity, multi-factoriality and heterogeneity.
- Trial name
- NCT05269927
- Testing
- EEG, DNA samples, clinical data
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Tic Disorders
Neuromodulation of Inhibitory Control in Tic Disorders
The present study aims to assess the effects of non invasive electrical stimulation of the vagus nerve via transcutaneous vagus nerve stimulation (tVNS) on cognitive functions, inhibitory and tic control in patients with tic…
- Trial name
- NCT05263414
- Testing
- tVNS
- Where
- Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Hereditary Spastic Paraparesis
SNAP: Measurement of the Subjective Perception of the Symptom in Hereditary Spastic Paraparesis (HSP)
The Self-Notion and Perception (SNAP) questionnaire developed at IRCCS E.Medea by Eleonora Diella and Roberta Morganti, arises from the need to quantify the subjective perception of the patient suffering from HSP of the typical…
- Trial name
- NCT04256681
- Testing
- SNAP questionnaire
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Glycogen Storage Disease
McArdle Disease Treatment by Ketogenic Diet
McArdle's disease or Glycogen storage disease type 5 (GSD5), the most common muscle glycogenosis, is a rare disabling condition with no effective treatment.
- Trial name
- NCT04292938
- Testing
- Low carbohydrate ketogenic diet
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- IRCCS Eugenio Medea
Ataxia, Cerebellar
Efficacy of Lycra Garments in Ataxic Subjects
The aim of this study iss to analyze the effect of Lycra garments in the axial stabilization in subjects affected by ataxia, both in acquired cerebellar injuries and malformative etiology.
- Trial name
- NCT04830904
- Testing
- personalized Lycra garments
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Eugenio Medea
Hemiparesis
VARA (Virtual and Augmented Reality Applications in Rehabilitation): Motor Rehabilitation Protocol With GRAIL for Patients Affected by Hemiparesis
The main goal of the study is to verify the efficacy of the GRAIL system in respect to the walking pattern improvement in a population of hemiparetic subjects.
- Trial name
- NCT04286997
- Testing
- GRAIL population
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Eugenio Medea
Traumatic Brain Injury
Functional and MRI Evaluation of the Robot-assisted and Traditional Rehabilitation Programs on the Muscle
Walk recovery is one of the goals of rehabilitation programs in patients with acquired brain injury. Recent experiences have shown the effectiveness of rehabilitation programs including traditional physiotherapy in combination…
- Trial name
- NCT04768192
- Testing
- Physical Rehabilitation without lokomat, Physical Rehabilitation with Lokomat
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Eugenio Medea
Developmental Dyslexia
Assessing the Generalizability of the Tachidino Protocol to Different Clinical Contexts
The study aims to document the effectiveness and acceptability of the intervention system for specific reading and writing disorders, in use at Scientific Institute (IRCCS) Medea, as applied and adapted to a different clinical…
- Trial name
- NCT04384718
- Where
- 3 sites in Italy
- Volunteers
- 32 people
- Sponsor
- IRCCS Eugenio Medea
Epilepsy
Efficacy Study of a Neuropsychological Rehabilitation Intervention for Children With Non-symptomatic Epilepsy
Patients with non-symptomatic epilepsy, even in the presence of a normative cognitive functioning, present different levels of neuropsychological weaknesses, especially in executive functions and social competences.
- Trial name
- NCT04292093
- Testing
- Home rehabilitation training, Home control activity
- Volunteers
- 48 people
- Sponsor
- IRCCS Eugenio Medea