Clinical trials: sponsored by Indiana University
Prostate Cancer
Ex-vivo Investigation of Beta Probe for Prostate Cancer Resection and Evaluation of PSMA-PET for Diagnosis of Intraprostatic Lesions
68Ga-PSMA is a radiopharmaceutical used with PET imaging for the detection of prostate cancer under a compassionate IND in patients who have presented with biochemical failure.
- Trial name
- NCT03213951
- Testing
- Experimental beta probe, PSMA-PET
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Indiana University
Peripheral Arterial Disease
Acute Effects of Leg Heating on Skeletal Muscle Blood Flow
The purpose of this study is to apply local heat to the legs, thighs and buttocks of patients with peripheral arterial disease and use PET/CT imaging with an injectable stable radiotracer to study direct measurement of blood flow…
- Trial name
- NCT03763357
- Testing
- Heat Therapy (HT)
- Sponsor
- Indiana University
Peripheral Neuropathy
Evaluation of an Exercise Intervention for Vincristine Induced Peripheral Neuropathy in Pediatric Cancer Patients
The purpose of this study is to better understand whether or not children with ALL can complete an exercise program during treatment and whether or not that program may impact peripheral neuropathy.
- Trial name
- Exercise (NCT03430674)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Indiana University
Tuberculosis
Clinical Decision-support Reminders to Improve IPT Initiation Among HIV Positive Adults in Western Kenya
The overall research objective is to evaluate the impact of implementing a reminder system for medical providers to improve TB case-finding and isoniazid preventative therapy (IPT) for adults living with HIV in western Kenya
- Trial name
- TBTech (NCT01934309)
- Testing
- TB reminders
- Where
- Kenya
- Volunteers
- 3,782 people
- Sponsor
- Indiana University
Cystic, Fibrosis
Zinc Status and Growth in Cystic Fibrosis
The purpose of this study is to improve the understanding of the relationship of zinc status and growth in infants and young children who were diagnosed with cystic fibrosis via newborn screening.
- Trial name
- NCT04302428
- Testing
- Serum Zn, Red Blood Cell Zn
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Indiana University
Type 1 Diabetes
Identification of β Cell Dysfunction in Relatives of Individuals With Type 1 Diabetes Mellitus
Despite the valuable information derived from older studies evaluating type 1 diabetes, the diabetes research community has, in large part, overlooked potential contributions of baseline abnormalities in β cell function to T1D…
- Trial name
- NCT04362917
- Testing
- There is no intervention
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Indiana University
Medication Histories in Outpatient Clinic Patients
Improving Laboratory Follow-up by Delivering an Enhanced Medication List to Outpatient Physician Practices
The investigators plan to develop a process to create an Enhanced Medication List. The INPC (Indiana Network for Patient Care) already obtains histories of medications dispensed by pharmacies from several sources: pharmacy…
- Trial name
- NCT01208987
- Testing
- Medication History was printed
- Where
- United States
- Volunteers
- 5,256 people
- Sponsor
- Indiana University
Mild Cognitive Impairment
Cognitive and Aerobic Resilience for the Brain
This is a randomized controlled trial (RCT) of the effectiveness of cognitive and exercise training versus control condition on cognitive function in older adults with mild cognitive impairment (MCI).
- Trial name
- CARB (NCT02390453)
- Testing
- Combined Cognitive and Physical, Cognitive, Physical
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Indiana University
Breast Cancer
Breast Cancer Self-Efficacy Scale for Partners
The concept of self-efficacy is a major predictor of physical, psychological, social and overall quality of life (QoL) among breast cancer survivors (BCS).
- Trial name
- BCSES-P (NCT05228210)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Indiana University
Concussion, Mild
The Combined Effect of Chronic Cannabis Use and Subconcussive Head Impacts on Brain Health
The purpose of this pilot study is to better understand the effects of chronic cannabis (THC) use on the neural responses to subconcussive head impacts, as a form of repetitive soccer headings.
- Trial name
- NCT04641832
- Testing
- Soccer heading
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Indiana University
Muscle Damage, Muscle Soreness
The Effects of Whey Protein Supplements on Markers of Exercise-induced Muscle Damage in Resistance-trained Individuals
Intense exercise can bring about various side effects to one's body. Less range of motion, increased pain sensitivity, increased muscle swelling, and decreased muscle strength can occur immediately after exercise.
- Trial name
- WheyProtein (NCT05100459)
- Testing
- Pasture-raised whey protein, Conventional whey protein
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Indiana University
Anxiety, Depression
Remember Stuff: A Dyadic-focused Technology to Support Persons With Alzheimer's Disease in the Community
Test the usability, perceptions and acceptability of a computer monitor for participant diagnosed with ADRD and their caregiver who will program the applications specifically for each individual to help them remember activities…
- Conditions
- Anxiety, Depression, Caregiver Burnout, Anxiety Generalized
- Trial name
- R/S (NCT04626804)
- Testing
- Remember Stuff: A Dyadic-focused Technology to Support Persons with Alzheimer's Disease in the Community
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Indiana University
Peripheral Arterial Disease
Home-based Leg Heat Therapy
The objective of this study is to evaluate the benefits of participating for 8 weeks in a home-based daily treatment with heat therapy (HT) or a thermoneutral control intervention, as assessed by vascular function, walking…
- Trial name
- HHT (NCT03763331)
- Testing
- Heat Therapy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Indiana University
Cognition
Daily Egg Consumption and Cognitive Function in Older Adults
The purpose of this study is to test the effects of provisioning twelve eggs weekly, incorporated into breakfast meals, on composite scores of executive functioning and memory using the CNSVS computerized test platform in older…
- Trial name
- NCT05460624
- Testing
- Egg-containing breakfast, Typical American-style breakfast excluding eggs
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Type1diabetes
Bone Health and Microbiome in Persons With Type 1 Diabetes
It is well-established that persons with type 1 diabetes (T1D) are at an increased risk for morbidity and mortality related to bone fracture due to poor bone health, however we do not fully understand the mechanism behind the…
- Trial name
- NCT04784975
- Testing
- No intervention
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Indiana University
Scoliosis
Pulmonary Compliance Changes During Manipulation of Early Onset Scoliosis and Cast Application
No interventions outside the normal course of patient care. The investigators will be collecting data at specified points throughout the casting process.
- Trial name
- NCT02558985
- Testing
- Casting
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Indiana University
Health Personnel Attitude
Feasibility and Acceptability of a Chaplain-Led Post-Code Debrief Intervention
The objective of this study is to increase the frequency and effectiveness of post code debriefs by piloting a novel intervention tool and partnering clinicians with board certified chaplains trained to facilitate group…
- Trial name
- PCD (NCT04874272)
- Testing
- Chaplain led post-code debrief
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Indiana University
Concussion, Mild
Reverse King-Devick Test and History of Multiple Concussions
The purpose of this study is to examine the effects of concussion history and reading direction on baseline King- Devick Test (KDT) performance, a common component of sideline concussion assessments.
- Trial name
- NCT04560400
- Testing
- Conventional King-Devick test, Reverse King-Devick test
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Indiana University
Breast Cancer
Memory Training Intervention for Breast Cancer Survivors
This is a randomized controlled trial to evaluate the ACTIVE memory training intervention and ACTIVE speed of processing training to waitlist, no-contact control conditions.
- Trial name
- NCT01497015
- Testing
- memory training, speed of processing training, waitlist control
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Indiana University
Survivorship, Cognitive Dysfunction
Biobehavioral Correlates of Cancer-related Cognitive Dysfunction and Its Co-occurring Symptoms
This descriptive, cross-sectional study will evaulate and fully characterize factors associated with cognitive dysfunction in Breast Cancer (BCS) and Colorectal Cancer (CRC) survivors that have cognitive concerns, and factors…
- Conditions
- Survivorship, Cognitive Dysfunction, Pain, Depression
- Trial name
- NCT04611620
- Testing
- Cognitive Dysfunction
- Where
- United States
- Volunteers
- 682 people
- Sponsor
- Indiana University
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