Clinical trials: sponsored by Indiana University
Heart Failure NYHA Class II, Heart Failure NYHA Class III
Cognitive Intervention to Improve Memory in Heart Failure Patients
Cognitive Intervention to Improve Memory in Heart Failure patients
- Conditions
- Heart Failure NYHA Class II, Heart Failure NYHA Class III, Heart Failure NYHA Class I
- Trial name
- Memoir-HF (NCT03035565)
- Testing
- Computerized Cognitive Training with Brain HQ, Computerized Crossword Puzzles
- Where
- 2 sites in United States
- Volunteers
- 276 people
- Sponsor
- Indiana University
Stroke, Depression
Treatment for Post-Stroke Depression
The purpose of this study is to evaluate a program of education, medicine, and monitoring for the treatment of depression after a stroke.
- Trial name
- NCT00029172
- Testing
- case management
- Where
- 4 sites in United States
- Volunteers
- 188 people
- Sponsor
- Indiana University
Colon Cancer, Colon Polyp
Quad Resection (Hot Snare vs Cold Snare vs Hot EMR vs Cold EMR)
The study will compare the use of cold snare, hot snare, cold EMR, and hot EMR for polyp resection. Although previous studies have compared two of the potential resection methods, no previous study has evaluated all four of the…
- Conditions
- Colon Cancer, Colon Polyp, Colon Adenoma
- Trial name
- NCT03462706
- Testing
- Cold Snare, Hot Snare, Cold EMR
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Indiana University
Spinal Cord Injuries
Task-specificity for Locomotor Recovery Following SCI
The primary goal of the proposed study is to identify the contributions of the amount of task-specific practice on locomotor (i.e., walking) recovery in patients with chronic (> 1 yr) motor incomplete spinal cord injury (iSCI).
- Trial name
- NCT03144388
- Testing
- Variable Stepping Training, Variable Non-specific Training
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Indiana University
Sport Injury, Attention-deficit/Hyperactivity Disorder
Effects of Subconcussive Head Impacts on Neural Integrity and Function in ADHD
The purpose of this study is to examine the acute neural responses to subconcussive head impacts in individuals with Attention-deficit/hyperactivity disorder (ADHD).
- Trial name
- NCT04880304
- Testing
- Soccer Heading
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Indiana University
Mental Illness, Shared Decision Making
Goal Elicitation, Treatment Prioritization, & Electronically-Practiced Discussion for Psychiatry
GET PrEPD-Psychiatry is a mixed-methods, developmental study to adapt a shared decision making (SDM) intervention to be specific for psychiatry decisions (Aim 1, previously completed), evaluate its feasibility and acceptability…
- Trial name
- GET-PrEPD (NCT04601194)
- Testing
- Coaching and Virtual Provider Program Practice
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Indiana University
Depression, Depressive Symptoms
Beating the Blues for Your Heart
The objective of this clinical trial is to evaluate whether a computerized depression treatment, delivered before the onset of heart disease, reduces the risk of heart disease in the future.
- Conditions
- Depression, Depressive Symptoms, Cardiovascular Disease (CVD), Coronary Artery Disease (CAD)
- Trial name
- BtB-Heart (NCT01605552)
- Testing
- Beating the Blues (BtB), Usual Care
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Indiana University
Gastrointestinal Neoplasms
Telephone Support for Advanced Gastrointestinal Cancer Patients and Caregivers
This trial tests telephone-based Acceptance and Commitment Therapy (ACT), a type of psychotherapy, to reduce fatigue interference with activities, mood, and cognition in advanced gastrointestinal (GI) cancer patients and family…
- Trial name
- NCT04010227
- Testing
- Acceptance and Commitment Therapy, Education/Support
- Where
- 2 sites in United States
- Volunteers
- 84 people
- Sponsor
- Indiana University
BRCA1 Mutation, High-grade Serous Ovarian Cancer
Breast Cancer BRCA1 Carriers: a Pilot Study
The purpose of this study is to examine how a single dose of MIFEPREX® (mifepristone) affects the breast tissue in patients with BRCA1 (a gene that normally acts to restrain the growth of cells in the breast, but if it mutates…
- Conditions
- BRCA1 Mutation, High-grade Serous Ovarian Cancer, TNBC - Triple-Negative Breast Cancer
- Trial name
- NCT05062174
- Testing
- Mifepristone 200 MG, Prophylactic mastectomy
- Where
- 2 sites in United States
- Sponsor
- Indiana University
Endoscopic Ultrasound
Comparison of Oxygenation Between Nasal PAP vs Nasal During Propofol-based Sedation for EUS
Randomized controlled single site study involves oxygenation, continuous positive airway pressure, and ventilation of subject via nasal mask and oxygenationvia closed facemask.
- Trial name
- SuperNo2VA (NCT04306211)
- Testing
- SuperNO2VA
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Indiana University
Depression, Anxiety
Efficacy of COMET on Prolific Participants
In this study, the investigators will test the effectiveness of a digital, single-session mental health intervention. There will be two conditions: the COMET intervention and the control group.
- Conditions
- Depression, Anxiety, Emotion Regulation
- Trial name
- COMET-Prol (NCT05379881)
- Testing
- Common Elements Toolbox (COMET)
- Where
- United States
- Volunteers
- 829 people, healthy volunteers welcome
- Sponsor
- Indiana University
Glioblastoma Multiforme, Anaplastic Astrocytoma
Pilot Study of Cabozantinib for Recurrent or Progressive Central Nervous System Tumors in Children
This pilot will study the feasibility and exploratory efficacy of using Cabozantinib for recurrent or refractory central nervous system tumors for which there are no curative options.
- Conditions
- Glioblastoma Multiforme, Anaplastic Astrocytoma, Malignant Brain Tumor, High Grade Glioma
- Trial name
- NCT02885324
- Testing
- Cabozantinib
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Indiana University
Neonatal Abstinence Syndrome, Neonatal Opioid Withdrawal
Optimal Morphine Dosing Schedule for Neonatal Abstinence Syndrome
Randomized pilot trial comparing scheduled morphine dosing with a weaning protocol to intermittent morphine dosing on an as-needed basis for newborns with neonatal abstinence syndrome.
- Conditions
- Neonatal Abstinence Syndrome, Neonatal Opioid Withdrawal, Neonatal Opioid Withdrawal Syndrome
- Trial name
- NCT04298853
- Testing
- Morphine PRN, Morphine scheduled
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Indiana University
Covid19
Adhesive Tape Placement on Patients' Masks in the Emergency Department Increases Compliance of Proper Face Mask Use
Methods 123 patients were enrolled in a randomized controlled trial at Eskenazi Hospital from April 2020 until October 2020. We permitted patients to either use their own mask (due to low resources institutionally) or we provided…
- Trial name
- NCT04812184
- Testing
- Tape Face Mask
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colonic Polyp
Effect of Epinephrine on Post-polypectomy Pain
Epinephrine is widely used in endoscopic mucosal resection of large polyps to prevent post-polypectomy bleeding. No previous studies looked at increase in immediate post-polypectomy pain with the use of epinephrine.
- Trial name
- NCT04065451
- Testing
- Epinephrine
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Indiana University
Breast Cancer, DCIS
Pilot Study of a an App to Improve Medication Adherence in Breast Cancer Survivors Receiving AIs
The purpose of this study is to evaluate the feasibility of an mobile-health strategy to improve patient-reported symptoms, promote life-saving medication adherence, and encourage healthy lifestyle behaviors in early stage breast…
- Trial name
- NCT04170920
- Testing
- LifeExtend-AI
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Indiana University
Anxiety, Caregiver Burden
Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults With ADRD
The purpose of the study is to test if Acceptance and Commitment Therapy (ACT), a behavioral intervention designed to increase psychological flexibility in the face of challenges, reduces anxiety associated psychological distress…
- Trial name
- (TACTICs) (NCT04780178)
- Testing
- Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults with Alzheimer's Disease and Related Dementias
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Indiana University
Peripheral Arterial Disease
Heat Therapy to Reduce Pain and Improve Walking Tolerance
The purpose of this study is to investigate whether exposure to heat therapy improves calf muscle oxygenation and enhances walking tolerance in patients with symptomatic Peripheral Arterial Disease (PAD).
- Trial name
- NCT03435835
- Testing
- Heat Therapy (HT)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Indiana University
Anxiety, Depression
Detecting and Evaluating Childhood and Anxiety and Depression Effectively in Subspecialties
The DECADES trial seeks to determine the comparative effectiveness of specialist-centered management of anxiety and depression vs.
- Trial name
- DECADES (NCT02773706)
- Testing
- Automated Psychology Services, Notification of Subspecialist
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Indiana University
Transition, Adolescent Behavior
Automated Youth-To-Adult Transition Planning Using Health Information ...
This study seeks to automate the process of youth to adult transition using an existing computerized decision support system in primary care.
- Trial name
- NCT03371875
- Testing
- Automated transition care reminders
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Indiana University
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