Clinical trials: sponsored by Indiana University
Lung Neoplasms
Functional Image and Molecular Markers to Predict Treatment Outcomes in Lung Cancer
This study is designed to apply various scans such as functional imaging, Fluorodeoxyglucose_Positron Emission Tomography (FDG-PET), 62Cu-ETS (Copper) PET, Ventilation/Perfusion Single Photon Emission Computerized Tomography (V/Q…
- Trial name
- NCT02117440
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Indiana University
Type 1 Diabetes
Advancing Diabetes Management in Adolescents Using Health Information Technology
The study will compare three treatment strategies to look at the best clinical outcomes. The investigator hypothesizes that the combined approach of a health information technology program plus a conflict-management contract will…
- Trial name
- NCT02115555
- Testing
- HIT-aided approach, Contracted conflict management system, HIT plus contracted conflict management
- Where
- 2 sites in United States
- Volunteers
- 129 people
- Sponsor
- Indiana University
Pediatric Obesity, Prediabetic State
Health Outcomes of Teens Participating in Summer Employment Immersion Programs
This study is a collaboration between investigators and two community partners: a youth employment program and an urban farm. The community partners hire 300+ adolescents for summer jobs at various organizations.
- Trial name
- NCT02886208
- Testing
- Measurement
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Indiana University
Schizophrenia
A Double-Blind Trial of Adjunctive Valacyclovir to Improve Cognition in Early Phase Schizophrenia
The primary aim of the study is to determine the efficacy of adjunctive valacyclovir, in comparison to placebo, to improve visual (Brief Visuospatial Memory Test) and working (composite score of the Spatial Span and Letter Number…
- Trial name
- VISTA (NCT02008773)
- Testing
- Valacyclovir HCI 500 mg tablets
- Where
- 13 sites in United States
- Volunteers
- 170 people
- Sponsor
- Indiana University
Dementia, Alzheimer's Disease
Indiana University Dementia Screening Trial
The purpose of the study is to conduct a randomized clinical trial assessing the harms and benefits of screening for dementia, compared to no screening for dementia, among 4,000 older adults, cared for in typical, primary care…
- Conditions
- Dementia, Alzheimer's Disease, Mild Cognitive Impairment
- Trial name
- IU-CHOICE (NCT01699503)
- Testing
- Collaborative Dementia Care Program
- Where
- 3 sites in United States
- Volunteers
- 4,005 people
- Sponsor
- Indiana University
Pervasive Developmental Disorder
Study of Aripiprazole in the Treatment of Pervasive Developmental Disorders
The purpose of this study is to develop a better tolerated and more effective pharmacologic treatment with individuals with Pervasive Developmental Disorder.
- Trial name
- NCT00870727
- Testing
- Aripiprazole oral product
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Indiana University
Carcinoma, Hepatocellular
Dose Escalation Study for Primary Hepatocellular Carcinoma
The purpose of this study is to determine the maximum tolerated dose of limited fractions of large dose radiation in an effort to achieve a biologically potent cancer therapy in selected patients with primary hepatocellular…
- Trial name
- SBF-HCC (NCT00243841)
- Testing
- Stereotactic Body Radiation
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Indiana University
Polyps
Cap-fitted Colonoscopy: a Randomized, Tandem Colonoscopy Study of Adenoma Miss Rates
This is a test in which a thin, black, flexible tube with a lighting system on the end is passed through the anus, into the rectum, in order to examine the large bowel or intestine, also called the colon.
- Trial name
- NCT00577083
- Testing
- Cap-fitted colonoscopy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Indiana University
TBI (Traumatic Brain Injury)
Improving Functional Ability in Chronic TBI With Intensive Rehabilitation Robotic Gait Training
The purpose of this study is to investigate changes in response to robotic gait training in individuals with a traumatic brain injury.
- Trial name
- NCT03438409
- Testing
- Robotic gait training
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Indiana University
Sickle Cell Anemia, Sickle Cell Disease
Novel Use Of Hydroxyurea in an African Region With Malaria
Multiple studies have shown that hydroxyurea has clinical efficacy in preventing acute painful episodes and reducing the need for blood transfusions in children with sickle cell anemia (SCA), but no study has been conducted in…
- Conditions
- Sickle Cell Anemia, Sickle Cell Disease, Malaria
- Trial name
- NOHARM (NCT01976416)
- Testing
- Hydroxyurea
- Where
- Uganda
- Volunteers
- 208 people
- Sponsor
- Indiana University
Alcohol Abuse, Nicotine Dependence Tobacco Product
Reactions to E-cigs and Alcohol
The purpose of this study is to 1) examine cognitive acuity following e-cig use (as compared to no e-cig use), 2) examine motor coordination following beer and e-cig use (as compared to beer consumption only).
- Trial name
- NCT03449017
- Testing
- E-cig use
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Indiana University
Transposition of Great Vessels
Late Function After Surgery for Transposition of the Great Arteries
The investigators proposed to review the exercise tolerance, cardiac function, and quality of life in patients born with transposition of the great arteries that have undergone surgery with either the Mustard or Senning…
- Trial name
- NCT03078413
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Indiana University
Colorectal Cancer, Colorectal Polyps
Does Inspection During Insertion Improve Adenoma Yields During Colonoscopy?
Colonoscopy is not a perfect test. It misses a substantial number of neoplastic lesions and has some risk of missing cancer. Nearly all work on detection during colonoscopy has focused on the withdrawal phase of the examination.
- Trial name
- NCT01035775
- Testing
- Inspection during insertion, Inspection during withdrawal
- Where
- 2 sites in United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Indiana University
Hepatitis B Virus
Interventions to Increase HBV Vaccinations in Sexually Transmitted Disease (STD) Clinics
The goal of this study is to evaluate two sets of interventions to increase acceptance of hepatitis B virus (HBV) vaccination in patients attending sexually transmitted disease (STD) clinics.
- Trial name
- NCT00739752
- Testing
- Non-Framed-Offered, Non-Framed-Recommended, Gain-Framed-Offered
- Where
- 2 sites in United States
- Volunteers
- 1,747 people, healthy volunteers welcome
- Sponsor
- Indiana University
Asthma, Exercise-Induced Bronchoconstriction
Effect of a Component of Fish Oil on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma
The primary aim of this study will be to evaluate the effects of Lyprinol® supplementation on airway inflammation and the bronchoconstrictor response to dry air hyperpnea in individuals with asthma.
- Trial name
- NCT01504646
- Testing
- Lyprinol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Pre-cancerous Geriatric Skin
Effect of Dermal Rejuvenation on the UVB Response of Geriatric Skin
The objective of this study is to examine the ability of dermal rejuvenation therapies to protect geriatric skin from ultraviolet light (UVB)-induced carcinogenesis.
- Trial name
- Laser Genesis (NCT02090894)
- Testing
- UV Light (Laser Genesis)
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Indiana University
Pulmonary Embolism
Nitric Oxide to Treat Pulmonary Embolism
This is a randomized study to treat subjects diagnosed with pulmonary embolism with inhaled nitric oxide or placebo (oxygen).
- Trial name
- NCT01939301
- Testing
- Inhaled Nitric Oxide
- Where
- 4 sites in United States
- Volunteers
- 78 people
- Sponsor
- Indiana University
Fluid Overload, Hypovolemia
Non-invasive Cardiac Output Monitor in Young Adults
The investigators would like to study cardiac output, stroke volume, and fluid responsiveness on young adult pediatric patients undergoing anesthesia and surgery with the use of the NICOM, a non-invasive monitor.
- Trial name
- NICOM (NCT02813915)
- Testing
- NICOM
- Volunteers
- 50 people
- Sponsor
- Indiana University
Anxiety
Canine-assisted ANxiety Reduction IN Emergency
The purpose of this study is to see if dogs can reduce the anxiety level of patients in the emergency department.
- Trial name
- CANINE (NCT03471429)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Indiana University
Correct Consistent Condom Use
A Self-Guided Intervention to Promote Condom Use Among African American Males
The Centers for Disease Control and Prevention has declared that AIDS is a "state of emergency" in the US for African Americans - young African American men are especially vulnerable in this epidemic.
- Trial name
- NCT01536730
- Testing
- Homework Intervention Strategy
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Indiana University
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