Clinical trials: sponsored by Indiana University
Paroxysmal Atrial Fibrillation
Focal Impulse and Rotor Modulation Ablation Trial for Treatment of Paroxysmal Atrial Fibrillation (FIRMAT-PAF)
Hypothesis: Focal Impulse and Rotor Modulation (FIRM) will substantially reduce or eliminate clinical atrial fibrillation in subjects with accepted indications for catheter ablation of paroxysmal AF, compared to standard…
- Trial name
- FIRMAT-PAF (NCT01925885)
- Testing
- PVI Ablation, FIRM Ablation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Indiana University
Cystic Fibrosis
Viral Pathogenesis of Early Cystic Fibrosis Lung Disease
The purpose of this study is to test the hypothesis that early viral infections alter the bacterial flora and inflammatory profile in the airway and accelerate progression of pulmonary disease in infants with cystic fibrosis.
- Trial name
- Early CF (NCT01973192)
- Where
- 4 sites in United States, Australia
- Volunteers
- 65 people
- Sponsor
- Indiana University
Chemotherapy Induced Nausea and Vomiting
Pilot Study of Olanzapine and Aprepitant to Prevent Nausea and Vomiting in Children Receiving Chemotherapy
The purpose of this study is to determine the feasibility of a larger trial comparing olanzapine and aprepitant and to obtain preliminary data on the effectiveness of these two medications to treat nausea and vomiting in children…
- Trial name
- NCT02097823
- Testing
- Olanzapine, Aprepitant
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Indiana University
GIST
Evaluation of a New EUS-guided Needle (ProCore) Comparing to EUS-TCB Needle (Quick-Core)
The purpose of this study is to evaluate a new EUS-guided biopsy needle (ProCore®) comparing it to conventional EUS-TCB needle (Quick-Core®) in the diagnosis of your suspicious disorder.
- Trial name
- NCT01768325
- Testing
- EUS-TCB needle (QuickCore) standard of care, EUS-Guided biopsy needle (ProCore)
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Indiana University
Intraventricular Hemorrhage, Sepsis
Placental Transfusion Project for Preterm Infants
The American College of Obstetrics and Gynecology, American Academy of Pediatrics and the World Health Organization have recently published recommendations related to placental transfusions in preterm infants.
- Conditions
- Intraventricular Hemorrhage, Sepsis, Necrotizing Enterocolitis
- Trial name
- NCT02400697
- Testing
- <30 wks gestation or 1500 grams
- Where
- United States
- Volunteers
- 2,856 people
- Sponsor
- Indiana University
Crohn's Disease, Protein Metabolism
Protein and Energy Metabolism in Pediatric Crohn's Disease
The metabolic response to Crohn's disease, including increased proteolysis and lipolysis and changes in energy expenditure, plays a significant role in the resulting malnutrition from which these patients suffer.
- Conditions
- Crohn's Disease, Protein Metabolism, Energy Metabolism
- Trial name
- NCT00583232
- Testing
- Stable isotope infusions
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Indiana University
Asthma
Using Computers to Assist in the Treatment of Asthma in a Pediatric Setting
This study seeks to improve physician adherence to four recommendations of the NHLBI asthma treatment guidelines: 1. Improve case detection of asthma among patients with pulmonary symptoms, 2.
- Trial name
- NCT01312805
- Testing
- CHICA Asthma Module, CHICA Control
- Where
- United States
- Volunteers
- 2,098 people, healthy volunteers welcome
- Sponsor
- Indiana University
HIV
Patient-Centered Disclosure Intervention for HIV-Infected Children
In the resource-limited settings where most HIV-infected children live, neither the most effective strategies to inform children of their HIV status, nor the impact of disclosure is well understood.
- Trial name
- HADITHI (NCT01947764)
- Testing
- HADITHI Intervention
- Where
- Kenya
- Volunteers
- 330 people
- Sponsor
- Indiana University
Glaucoma
The Study of Ocular Hemodynamics With Glaucoma Progression
To determine the relationships between ocular hemodynamics and glaucomatous optic neuropathy progression.
- Trial name
- IGPS (NCT01145911)
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Indiana University
Fibromyalgia
Drug and Talk Therapy for Fibromyalgia
Fibromyalgia Syndrome (FMS) afflicts 2% of the U.S. population and have huge individual and societal costs in terms of quality of life, social and work functioning, health care use, and lost productivity.
- Trial name
- NCT01038323
- Testing
- CBT and milnacipran, Educational with milnacipran
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Indiana University
Vincristine Induced Neuropathy
A Pilot Study Investigating the Effects of Acetyl-L-Carnitine and Vincristine-Induced Neuropathy in Pediatric Patients With ALL
The purpose of this study is to see if a drug called Acetyl-L-Carnitine can help prevent painful nerve damage and nerve pain which is caused by vincristine, a drug used in chemotherapy in children being treated for newly…
- Trial name
- ALC (NCT02598622)
- Testing
- Acetylcarnitine
- Volunteers
- 8 people
- Sponsor
- Indiana University
Schizophrenia
Effects of RG1068 (Secretin) on Information Processing in Schizophrenia
The overarching purpose of the proposed study is to determine Secretin's (RG1068) psychophysiological effects on measures of motor learning, affective, and inhibitory information processing in individuals with schizophrenia.
- Trial name
- NCT00235274
- Testing
- Subcutaneous Secretin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Indiana University
Dementia, Alzheimer's Disease
Comparative Research of Alzheimer's Disease Drugs
Conduct a comparative effectiveness clinical trial of medication treatment for behavioral symptoms of Alzheimer's disease in a group of real-world memory care clinics with enhanced access to the Indiana Network for Patient Care.
- Trial name
- COMET-AD (NCT01362686)
- Testing
- Donepezil, Galantamine, Rivastigmine
- Where
- 5 sites in United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Polycystic Ovary Syndrome
Evaluation of Oral Lipid Ingestion in Relation to Ovarian Androgen Secretion in Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to determine the relationship between lipid-induced inflammation and ovarian androgen secretion in women with polycystic ovary syndrome (PCOS); and to examine the effect of salsalate and polygonum…
- Trial name
- ELI-ROAS (NCT01489319)
- Testing
- Salsalate
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Indiana University
Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia
The Effectiveness of the Neutropenic Diet in Pediatric Oncology Patients
The purpose of this study is to determine if FDA approved food safety guidelines are equivalent to a low bacterial diet (the neutropenic diet) with respect to the acquisition of infections during neutropenia in a sample of…
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Non-Hodgkins Lymphoma, Sarcoma
- Trial name
- NCT00726934
- Testing
- Food Safety Guidelines, Neutropenic Diet
- Where
- 6 sites in United States
- Volunteers
- 149 people
- Sponsor
- Indiana University
Breast Abnormalities
Testing New Method of Analyzing MR Images
Preliminary imaging study to test for future use of this MRI-imaging for evaluating anti-angiogenesis treatment.
- Trial name
- NCT00630318
- Testing
- MRI
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Indiana University
HIV, HIV Infections
Extending HIV Care Beyond the Rural Health Center
The objective of this application is to develop and assess a system which uses non-clinician extenders to provide selected aspects of HIV care in rural western Kenya.
- Trial name
- NCT00371540
- Testing
- Home visit by community care coordinators
- Where
- Kenya
- Volunteers
- 208 people
- Sponsor
- Indiana University
Diabetes, Gestational
Diagnosis of Gestational Diabetes in Eldoret, Kenya
The objective of this study is to determine the most appropriate and effective approach for the diagnosis of gestational diabetes mellitus (GDM) among pregnant women receiving focused antenatal care at Moi Teaching and Referral…
- Trial name
- NCT02978807
- Testing
- Point of care and venous screening
- Volunteers
- 935 people, healthy volunteers welcome
- Sponsor
- Indiana University
Tuberculosis, Iron Deficiency Anemia
Universal Screening for Tuberculosis and Anemia With the CHICA System
The CHICA system is a clinical decision support system that uses adaptive turnaround documents to provide point-of-care information to clinicians.
- Trial name
- NCT01322841
- Testing
- CHICA Diagnosis Module
- Where
- United States
- Volunteers
- 2,239 people, healthy volunteers welcome
- Sponsor
- Indiana University
Fibromyalgia
Novel Use of (Oral) Ketotifen for the Treatment of Fibromyalgia: A Pilot Study
The purpose of this 10-week study is to determine the effects of a medication called Ketotifen on pain sensitivity; and fibromyalgia-related pain.
- Trial name
- KetoforFMS (NCT01553318)
- Testing
- Ketotifen
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Indiana University
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