Clinical trials: sponsored by Indiana University
Attention Deficit Hyperactivity Disorder
Comparative Effectiveness of Primary Care-based Interventions for Pediatric ADHD
Attention-deficit hyperactivity disorder (ADHD) is the most common neurobehavioral disorder of childhood, affecting approximately 8% of youth.
- Trial name
- NCT02105142
- Testing
- ADHD Group Visits, ADHD Group Visits plus Online Discussion Portal, Computer Decision Support
- Where
- 5 sites in United States
- Volunteers
- 81 people
- Sponsor
- Indiana University
Cystic Fibrosis, Pseudomonas Aeruginosa
A Comparator Study Evaluating Microbiological Resistance and Effects of Alternating Inhaled Antibiotic Therapies
This is a pilot study of inhaled antibiotic regimens is a pilot study examining clinical and laboratory endpoints of patients on inhaled antibiotic treatments.
- Trial name
- NCT01319253
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Indiana University
Prolonged QT Interval in EKG and Sudden Death
Influence of Progesterone Administration on Drug-Induced QT Interval Lengthening
Female sex is an independent risk factor for the potentially fatal drug-induced arrhythmia (irregular heartbeat) known as torsades de pointes (TdP), which is associated with prolongation of the corrected QT (QTc) interval on the…
- Trial name
- NCT01929083
- Testing
- Progesterone, Ibutilide
- Where
- 2 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Indiana University
Pulmonary Hypertension
Safety Study of Gleevec® in Children With Pulmonary Hypertension
The purpose of this study is to find out if the drug, Gleevec, is safe and effective in treating children with Pulmonary Hypertension.
- Trial name
- NCT00583115
- Testing
- Gleevec
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Indiana University
Breast Neoplasms
A Study Inhibiting Telomerase to Reverse Trastuzumab Resistance in HER2+ Breast Cancer
A study to evaluate safety and biologic effects of giving GRN163L in combination with trastuzumab in patients diagnosed with HER2+ metastatic breast cancer that is resistant to therapy with trastuzumab.
- Trial name
- NCT01265927
- Testing
- GRN163L in combination with trastuzumab
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Indiana University
Depression, Postpartum
Follow up of Mothers Suspected of Postpartum Depression
Postpartum depression (PD) is a serious and disabling mental health condition that affects 10-15% of women after childbirth. Low-income minority women are disproportionately affected.
- Trial name
- NCT02559986
- Testing
- telephone interview
- Volunteers
- 73 people
- Sponsor
- Indiana University
Coronary Artery Disease
Effects of Short Term, High Dose Atorvastatin Therapy on Periprocedural Myonecrosis and Platelet Inhibition After Percutaneous Coronary Intervention (PCI)
This research study plans to evaluate the use of atorvastatin in patients with coronary artery disease given immediately before PCI and whether it will decrease the amount of heart damage after PCI.
- Trial name
- ESTATE (NCT00979940)
- Testing
- Atorvastatin
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Indiana University
Overweight
Delivering Geospatial Intelligence to Health Care Providers
Physician counseling for physical activity, dental services, and academic support services such as tutoring could be improved through physician knowledge of local community resources and physician counseling directing patients to…
- Trial name
- CHICA GIS (NCT01567228)
- Testing
- CHICA GIS (enhanced electronic medical record)
- Where
- United States
- Volunteers
- 1,076 people
- Sponsor
- Indiana University
Leukemia, Myeloid, Acute, Leukemia, Lymphoid
A Phase I Trial of Alloreactive Cell Infusion Following Transplantation of Haplotype Cells in Patients With Myeloid Malignancies
The purpose of this study is to determine the maximum tolerated dose of alloreactive NK cells that can be transfused following stem cell transplant.
- Conditions
- Leukemia, Myeloid, Acute, Leukemia, Lymphoid, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic
- Trial name
- NCT00569179
- Testing
- CliniMACS CD34 Reagent System
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Indiana University
Breast Cancer Stage IV, Breast Cancer Stage I
Quantitation of Endothelial Progenitor Cells as Markers of Tumor Angiogenesis in Breast Cancer
We propose to quantitate endothelial progenitor cells (EPCs) in early and advanced breast cancer patients. Peripheral blood will be drawn from the eligible patients.
- Conditions
- Breast Cancer Stage IV, Breast Cancer Stage I, Breast Cancer Stage II
- Trial name
- EPC (NCT00393341)
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Indiana University
Pediatric Patient (1m-21y), ICU Admission
Pediatric Intensive Care Units (ICUs) at Emory-Children's Center Glycemic Control: The PedETrol Trial
The primary goal of this project is to determine whether normalizing hyperglycemia is a safe approach to improve multisystem organ function in critically ill children requiring intensive care.
- Conditions
- Pediatric Patient (1m-21y), ICU Admission, Hyperglycemia
- Trial name
- PedETrol (NCT01116752)
- Testing
- Active Glycemic Control Strict (80-140mg/dL) vs. Conservative (190-220mg/dL) (with or without Continuous Glucose Monitoring)
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Indiana University
Hypoglycemia Hyperglycemia
Pediatric Critical Illness Hyperglycemia and Glycemic Control Registry
The objective in this project is to assemble a consortium of pediatric critical care centers of varying size, acuity, and composition to evaluate our glycemic control protocol on at least 250 children with hyperglycemia in…
- Trial name
- NCT01116674
- Where
- 3 sites in United States
- Volunteers
- 206 people
- Sponsor
- Indiana University
Hepatocellular Carcinoma
Lenalidomide in Combination With a Fixed Dose of Sorafenib for the Treatment of Hepatocellular Carcinoma
The purpose of this study is to evaluate the combination of Revlimid® (lenalidomide) and Nexavar® (sorafenib) for the treatment of hepatocellular carcinoma that can't be cured with surgery.
- Trial name
- NCT01348503
- Testing
- Lenalidomide, Sorafenib
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Indiana University
Proteinuria
Bariatric Surgery and the Kidney
The purpose of the project is to study the relationship between post-bariatric surgery changes in weight and renal parameters.
- Trial name
- NCT01410994
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Indiana University
Kidney Diseases
The Effects of Obesity and Protein Intake on the Kidney
The purpose of this study is to determine if being overweight and eating lots of protein causes separate changes in the kidney that lead to kidney disease over time.
- Trial name
- NCT00244790
- Testing
- Diet
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Indiana University
Dementia
Perceptions Regarding Investigational Screening for Memory Problems in Primary Care
The purpose of this study is to conduct a cross-sectional survey of primary care patients to better understand their perceptions of the risks and benefits of a screen and subsequent diagnostic confirmation of dementia.
- Trial name
- PRISM-PC (NCT00759252)
- Where
- United States
- Volunteers
- 954 people, healthy volunteers welcome
- Sponsor
- Indiana University
Diabetic Kidney Disease
Very Low Calorie Diet for Diabetic Kidney Disease
The purpose of this study is to determine whether a very low calorie diet will stabilize or improve diabetic kidney disease.
- Trial name
- NCT01671969
- Testing
- very low calorie diet
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Indiana University
Cardiovascular Disease
Efavirenz Versus Rilpivirine on Vascular Function, Inflammation, and Oxidative Stress
The purpose of this study is to compare the cardiovascular profiles of efavirenz and rilpivirine, which are two drugs used to treat HIV infection.
- Trial name
- NCT01585038
- Testing
- Efavirenz, Rilpivirine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Indiana University
Calprotectin, Inflammatory Bowel Disease
Value of Fecal Calprotectin
For the main goal - the accuracy of calprotectin for the diagnosis of IBD - calprotectin levels will be compared between patients with and without a diagnosis of IBD and the sensitivity, specificity and accuracy will be…
- Trial name
- NCT00577928
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Indiana University
Lymphoma, Inflammatory Bowel Disease
Prevalence of Lymphoma in IBD
Patients with inflammatory bowel disease (IBD) may be at increased risk of lymphoma. The majority of lymphomas in patients with IBD occur in areas of active inflammation.
- Trial name
- NCT00577538
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Indiana University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.