Clinical trials: sponsored by Indiana University
HPV Vaccine Attitudes, HPV Vaccine Intention
HPV Vaccine Acceptability Among Young Men Who Have Sex With Men
The FDA has recently approved Gardasil for the prevention of anal cancer in people aged 9-26. Men who have sex with men (MSM) have disproportionately high rates of anal cancer and could benefit greatly from vaccination.
- Trial name
- NCT01535794
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Indiana University
Chronic Kidney Disease
Calcium and Phosphorus Balance and Calcium Kinetics in Patients With Stage 3/4 Chronic Kidney Disease
The purpose of this study is to gain a better understanding of calcium absorption and metabolism in patients with Chronic Kidney Disease (CKD) using calcium balance and kinetic methods.
- Trial name
- NCT01161407
- Testing
- 1500 mg/d elemental calcium as calcium carbonate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Indiana University
Liver Transplantation
Pilot Study With Peginterferon, Ribavirin, and Boceprevir Prior to Transplantation to Clear Virus in Hepatitis C Genotype 1 Infected Individuals Undergoing Orthotopic Liver Transplantation
Currently, there is no treatment standard for use of anti-HCV (hepatitic C virus) medications for those preparing for a liver transplant.
- Trial name
- NCT01909401
- Testing
- boceprevir
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Indiana University
HIV Infection
Comparing Blood Vessel Endothelial Function in HIV-Infected People and Matched HIV-Uninfected People
The blood vessels that carry blood from the heart to the rest of the body are normally capable of relaxing and constricting when needed to provide more or less blood to the body.
- Trial name
- NCT00919724
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Indiana University
Asperger's Disorder, Pervasive Developmental Disorder
A Study of Aripiprazole in Children and Adolescents With Aspergers and Pervasive Developmental Disorder.
The purpose of this study is to develop a better tolerated and more effective pharmacologic treatment for individuals with Asperger's Disorder and Pervasive Developmental Disorder.
- Trial name
- NCT00198055
- Testing
- aripiprazole
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Indiana University
Germ Cell Tumor
Phase II Study of Cisplatin Plus Epirubicin Salvage Chemo in Refractory Germ Cell Tumors
This study proposes to evaluate the combination of cisplatin plus epirubicin in patients with refractory germ cell tumor not amendable to cure with surgery or standard platinum salvage chemotherapy.
- Trial name
- NCT00198172
- Testing
- Cisplatin plus Epirubicin
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Indiana University
Breast Cancer
Genomic & Proteomic Analysis of Docetaxel & Capecitabine as Primary Chemo for Stage II-III Breast Cancer
The primary objective of this study is to determine the efficacy \& toxicity of combined docetaxel \& capecitabine as primary chemo for subjects w/ stage II-III breast cancer.
- Trial name
- NCT00198237
- Testing
- docetaxel & capecitabine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Indiana University
Thymic Cancer, Thymoma
A Study to Test the Safety and Efficacy of Erlotinib Plus Bevacizumab to Treat Advanced Thymoma and Thymic Cancer
The purpose of this study is to determine the rate of response with the combination of erlotinib and bevacizumab in previously treated patients with thymoma or thymic carcinoma, and to determine potential molecular markers that…
- Trial name
- NCT00369889
- Testing
- bevacizumab, Erlotinib
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Indiana University
Thymic Carcinoma
Pilot Study of Imatinib (Gleevec) as Treatment for Advanced Thymic Carcinoma
This study is important to demonstrate if single agent activity is noted for patients with thymic tumors over expressing c-kit and/or PDGF.
- Trial name
- NCT00314873
- Testing
- Gleevec (imatinib)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Indiana University
ADHD
Exploring the Group Visit Model for Pediatric ADHD Management in the Medical Home
Attention deficit hyperactivity disorder (ADHD) affects 8% of US youth. Even though evidence shows medications are effective in reducing ADHD symptoms, many families experience ongoing parenting stress around parent-child…
- Trial name
- NCT02145793
- Testing
- ADHD Group Curriculum
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Indiana University
HIV, Vascular Diseases
Pentoxifylline and Combination Antiretroviral Therapy to Improve Blood Vessel Function in HIV-Infected People
People infected with HIV have a greater risk of developing cardiovascular disease than people not infected with HIV. This may be due to increased inflammation in the blood vessels.
- Conditions
- HIV, Vascular Diseases, Cardiovascular Diseases, Atherosclerosis
- Trial name
- NCT00864916
- Testing
- Combination antiretroviral therapy (cART), Pentoxifylline
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Indiana University
Colorectal Cancer
Patients' Opinions and Responses to the National Cancer Institute's Colorectal Cancer Risk Assessment Tool
Little is known about the impact of risk assessment tools on decision-making by patients and clinicians. In particular, even though the NCI Colorectal Cancer Risk Assessment Tool is one of the most prominent risk assessment tools…
- Trial name
- CRC-RAT (NCT01803009)
- Testing
- Patient views NCI CRC RAT, View presentation regarding current chance of having an advanced adenoma
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Indiana University
Pancreatic Cancer
Pilot Study Using Neoadj Chemo-Rad & EGFR-tyrosine Kinase Inhibitor for Potentially Resectable Pancreatic Cancer
To determine the feasibility and toxicity of neoadjuvant hypofractioned radiotherapy concurrently with weekly gemcitabine and an EGFR tyrosine-kinase inhibitor (OSI-774, Tarceva) in the treatment of patients with resectable…
- Trial name
- NCT00243854
- Testing
- Tarceva
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Indiana University
Medication Reconciliation
Medication Reconciliation Technology to Improve Quality of Transitional Care
This study addresses the problem of inadequate medication reconciliation as patients cross boundaries between inpatient and outpatient care (ambulatory care).
- Trial name
- MedMatch (NCT01195051)
- Testing
- Electronic medication reconciliation
- Where
- United States
- Volunteers
- 4,818 people
- Sponsor
- Indiana University
Cardiovascular Diseases, Heart Diseases
Blood Pressure Control in Juveniles - Longitudinal Study
To correlate dietary factors and changes in pressor substances, including aldosterone and norepinephrine, with blood pressure during growth and sexual development from childhood through adolescence.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension
- Trial name
- NCT00005181
- Sponsor
- Indiana University
Minimal Hepatic Encephalopathy
Study of Lactulose in Children With Chronic Liver Disease
Pediatric patients with chronic liver disease may have Minimal Hepatic Encephalopathy(MHE)which can cause changes in behavior,intelligence and neurological function.By utilizing cognitive and developmental testing we will…
- Trial name
- MHE (NCT00811434)
- Testing
- Lactulose
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Indiana University
Human Papillomavirus Infection
Brief Interventions to Increase HPV Vaccine Acceptance in School-based Health Centers
Using health behavior theories and theories related to the effects of persuasive messages (i.e., inoculation theory), we plan to: 1.
- Trial name
- NCT01087164
- Testing
- Compliance, Message sidedness
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Indiana University
Glaucoma
Aqueous Suppressant Versus Aqueous Outflow on Ocular Blood Flow
The purpose of this study will be to compare the aqueous production suppressant to aqueous outflow drugs in terms of the response to known vascular parameters.
- Trial name
- NCT01308788
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Indiana University
Glaucoma
Trusopt and Cosopt; Ocular Perfusion Pressure and Blood Flow: New Long-term Prospective Data
To analyze Cosopt® in terms of its effects on ocular perfusion pressure and comprehensive ocular blood flow and in relation to visual field progression and optic nerve structural changes in an ongoing 3 year prospective study…
- Trial name
- NCT01145898
- Testing
- (Cosopt®, prostaglandin)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Indiana University
Parental Vaccine Intentions for Their Children
Altruistically Framed Messages and Impact on Parents' Reported Willingness to Immunize Their Children
The purpose of this study is to examine the impact of different message framing (i.e., communication strategies) on parents' intentions to vaccinate their infants for measles, mumps, and rubella.
- Trial name
- NCT02015689
- Testing
- Benefits to Child, Benefits to Society, Benefits to Child and Society
- Volunteers
- 802 people
- Sponsor
- Indiana University
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