Clinical trials: sponsored by Institut Paoli-Calmettes
Cancer Related Fatigue, Breast Cancer
Feasibility Study of an Adapted and Supported Water Polo Program to Reduce Fatigue Related to Cancer and Improve Psychological and Social Recovery in Patients With Breast Cancer Remission
The main objective of the study is to assess the feasibility of a coached physical activity program in the form of an accompanied and adapted water polo program by evaluating the interest aroused in patients for this proposal.
- Trial name
- AQUA-POLO (NCT04235946)
- Testing
- accompanied and adapted water polo program
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Institut Paoli-Calmettes
Psychological, Oncology
"Patient Autonomie" in People With Cancer
In France, the notion of autonomy concerning the patient's place in the healthcare system has been written into legal texts for several years.
- Trial name
- AUPAC (NCT04517773)
- Testing
- writting test
- Volunteers
- 90 people
- Sponsor
- Institut Paoli-Calmettes
Solid Tumor, Hematologic Malignancy
An Evaluation of Patients Access to Their Electronic Medical Records Via the IPC Connect Application
The aim of our study is to investigate the effect of providing patients access to their electronic medical records Via the IPC Connect Application on their A Survey will be proposed to all outpatients with a solid or hematologic…
- Trial name
- ADN-CO (NCT04496375)
- Testing
- Survey
- Volunteers
- 8,000 people
- Sponsor
- Institut Paoli-Calmettes
Breast Cancer, Colorectal Cancer
Assessment of Outpatient Digital Follow-up of Patients Over 70 Years of Age Undergoing Chemotherapy Treatment
adherence of digital follow-up in a population of elderly patients.
- Conditions
- Breast Cancer, Colorectal Cancer, Lung Cancer
- Trial name
- E-SN@P PROJECT (NCT03959774)
- Testing
- IPC NET
- Where
- 4 sites in France
- Volunteers
- 119 people
- Sponsor
- Institut Paoli-Calmettes
Mastectomy, Breast Reconstruction
Mastectomy With Retention of the Nipple-areola Complex, Robot-assisted or Not, and / or Immediate or Seconday Reconstruction by Latissimus Dorsi Flap, Robot-assisted or Not.
Phase III, non-randomized, monocentric, observational, prospective trial. It is planned to recruit a total of 480 patients, including 240 patients receiving mastectomy with preservation of the nipple-areola complex and 240…
- Trial name
- RMR (NCT04457167)
- Testing
- Robot-assisted, Not robot-assisted surgery
- Where
- France
- Volunteers
- 480 people
- Sponsor
- Institut Paoli-Calmettes
Malignant Biliary Obstruction
Evaluation of a New Metal Biliary Stent of 12-mm Diameter: a Case Control Study
Biliary stent allows the drainage of the bile ducts palliatively or preoperatively in the event of malignant biliary stenosis, and a biliary calibration in the event of benign stenosis.
- Trial name
- BIGDIAM (NCT04405752)
- Testing
- 12-mm metallic biliary stent, 10-mm metallic biliary stent
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Institut Paoli-Calmettes
Non-Hodgkin Lymphoma
Safety and Efficacy of Revlimid® (Lenalidomide) With Mabthera® (Rituximab) in Non-Hodgkin's Lymphoma
The incidence of non-Hodgkin's lymphoma (NHL) is steadily increasing worldwide. At present, it is the sixth most commonly diagnosed cancer in France, with 10 000 estimated new cases and 5200 deaths annually.
- Trial name
- R2 (NCT01939327)
- Testing
- Lenalidomide/Rituximab
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Institut Paoli-Calmettes
Metastatic Breast Cancer
Eribulin in Brain Metastases From HER2-negative Breast Cancer
To evaluate the efficacy of eribulin for treatment of HER2-negative breast cancer brain metastases (BCBM)
- Trial name
- ERIBRAIN (NCT03637868)
- Testing
- Eribulin
- Where
- 7 sites in France
- Sponsor
- Institut Paoli-Calmettes
Ovarian Carcinoma
Circulating Tumor DNA as an Early Marker of Recurrence and Treatment Efficacy in Ovarian Carcinoma
Prospective multicentre assay to assess ctDNA value for ovarian cancer monitoring and disease recurrence after front-line treatment.
- Trial name
- CIDOC (NCT03302884)
- Testing
- biological sampling
- Where
- 3 sites in France
- Volunteers
- 150 people
- Sponsor
- Institut Paoli-Calmettes
Solid Tumor, Adult
Feasibility of a Process of Digital Validation of Chemotherapies in a Day Treatment Unit
The aim of CPV 2.0 study is to evaluate a process of digital prevalidation of outpatients chemotherapy thanks to a numeric application.
- Trial name
- CPV2-0 (NCT03977766)
- Testing
- Chemotherapy prevalidation
- Volunteers
- 150 people
- Sponsor
- Institut Paoli-Calmettes
Cancer, Treatment-Related
Number of Weekly Steps, Fatigue, Quality of Life, Well-being During Cancer Treatment: Impact of Recommendations Strengthened by the Provision of Web Interface and Tele-coaching.
study to correlate this level of objective physical activity with the levels of fatigue and quality of life in cancer patient being treated.
- Trial name
- PODOMETRE (NCT03961451)
- Testing
- Podometer
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Institut Paoli-Calmettes
Non-muscle-invasive Bladder Cancer
Bladder PREserVation by RadioTherapy and Immunotherapy in BCG Unresponsive Non-muscle Invasive Bladder Cancer
About two-thirds of newly diagnosed cases of bladder cancer are non-muscle-invasive bladder cancer (NMIBC). It is advocated that patients with high-risk NMIBC receive an adjuvant course of intravesical Bacille Calmette-Guerin…
- Trial name
- PREVERT (NCT03950362)
- Testing
- Avelumab, Radiotherapy
- Volunteers
- 67 people
- Sponsor
- Institut Paoli-Calmettes
Oncology
Database for Data Collection in the Context of an Enhanced Recovery After Surgery Program in Oncology Surgery
Enhanced Recovery After Surgery Programs (ERP) includes multimodal approaches of perioperative patient's clinical pathways designed to achieve early recovery after surgery and a decreased length of hospital stay (LOS).
- Trial name
- BDD RAAC (NCT03950011)
- Testing
- Enhanced recovery after surgery program
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Institut Paoli-Calmettes
Myelodysplastic Syndromes
Institut Paoli Calmettes Myelodysplastic Syndromes Database
Database of Institut Paoli-Calmettes patients diagnosed with Myelodysplastic Syndromes
- Trial name
- NCT03275480
- Where
- France
- Volunteers
- 10,000 people
- Sponsor
- Institut Paoli-Calmettes
Hematological Diseases
Study Evaluating the Efficacy of Allogeneic Transplant Conditioning With Adaptive Dose Busulfan Intravenous (Busilvex®) in Patients at High Risk of Carrying Blood Diseases
Determine the efficiency of a myéloablative conditioning associating Fludarabine, Thymoglobuline, and intravenous Busulfan with adapted dose, according to a pharmacokinetics realized in the first day of administration (or J-6 of…
- Trial name
- BX-PK (NCT02483325)
- Testing
- Allogeneic transplant conditioning
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Institut Paoli-Calmettes
Haematologic Disease (Cancer), Onco-coaching of Sport- Inspirated
Onco-coaching of Sport-inspired for the Social, Professional and Psychological Restoring of the Patients in Cancer Remission After Allogeneic Transplantation of Hematopoietic Stem Cells
Sometimes, certain patients, while the treatment comes to an end and while a remission is possible, present psychological and emotional difficulties.
- Trial name
- REBOND (NCT03272789)
- Testing
- Interviews with coach
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Institut Paoli-Calmettes
Pancreatectomy
Psychological Effect of the pancréatectomy: a Feeling of Strangeness
The cancer of the pancreas represents 1,8 % of cancers in France, with 9040 new cases in 2011 (France). This cancer is known to be of dark forecast.
- Trial name
- REPPSE (NCT03686592)
- Testing
- Measurement of body awareness
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Institut Paoli-Calmettes
Barretts Esophagus With Dysplasia
Impact of Histologic Concordance Between Biopsies and the Endoscopic Resection Specimen, in the Treatment of Barrett's Esophagus in Dysplasia, on the Recurrence of Dysplasia
Influence of histological concordance on the risk of recurrence: the histological concordance being the comparison between the biopsies and the endoscopic resection piece and its concordant response rate.
- Trial name
- PatheBarett (NCT03685799)
- Testing
- Pathological revision
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Institut Paoli-Calmettes
Liver Surgery
Institut Paoli Calmettes Hepatic Surgery Database
Database of patients who undergo hepatic surgery for: benign diseases, primary or secondary liver cancer at Institut Paoli-Calmettes
- Trial name
- BDD CHIRHEP (NCT03686137)
- Testing
- Data collection
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- Institut Paoli-Calmettes
Lymphoma, B-Cell
Indication to Transplant Patients With High Risk B Cells Lymphoma in Metabolic Complete Remission?
The autograft of patients with prognostically unfavourable B-cells lymphoma cells in first remission remains controversial, in particular since the association of Rituximab with chemotherapy.
- Trial name
- NCT03681938
- Testing
- Autograft
- Where
- France
- Volunteers
- 183 people
- Sponsor
- Institut Paoli-Calmettes