Clinical trials: sponsored by KU Leuven
COPD
Exacerbation and Training in Patients With Chronic Obstructive Pulmonary Disease
When patients with chronic obstructive lung disease (COPD) are admitted to the hospital with a severe exacerbation they lose muscle strength. This muscle weakness predisposes these patients to further hospital admissions.
- Trial name
- EXTRA (NCT00877084)
- Testing
- Resistance training, Usual care
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- KU Leuven
Healthy
Tolerance and Prebiotic Activity of Arabinoxylan-Oligosaccharides in Healthy Subjects
The purpose of the study is to evaluate the tolerance of a higher dose of arabinoxylan-oligosaccharides (AXOS) and their prebiotic activity in healthy subjects.
- Trial name
- NCT00852813
- Testing
- arabinoxylan-oligosaccharides (AXOS)
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Healthy
Effects of Arabinoxylan-Oligosaccharides Compared to Other Prebiotics in Healthy Subjects
The purpose of the study is to evaluate the effects of arabinoxylan-oligosaccharides (AXOS) on the colonic metabolism and microbial composition, and to compare these effects with the reference prebiotic fructo-oligosaccharide…
- Trial name
- NCT00853034
- Testing
- FOS-IN, AXOS
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Critical Illness, Intensive Care
Early Exercise Training in Critically Ill Patients
This randomized controlled trial was designed to investigate whether a daily training session using a bedside cycle ergometer, started early in stable critically ill patients with an expected prolonged ICU stay, could induce a…
- Conditions
- Critical Illness, Intensive Care, Muscle Weakness, Deconditioning
- Trial name
- NCT00695383
- Testing
- Bedside cycle exercise therapy, Standard physiotherapy program
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- KU Leuven
COPD, Emphysema
Thorax Enlarging Surgery: a Novel Surgical Approach to Emphysema
There is a growing population of end-stage COPD patients for whom surgical treatments like lung transplantation and lung volume reduction surgery are not possible.
- Trial name
- TE (NCT00650559)
- Testing
- Chest wall enlargement
- Where
- Belgium
- Volunteers
- 4 people
- Sponsor
- KU Leuven
Renal Transplantation
Gene Polymorphisms in Tacrolimus Drug Interactions
A retrospective analysis of the influence of gene polymorphisms on drug interactions between calcineurin-inhibitors and concomitant drugs in renal transplant patients.
- Trial name
- DDI-TAC (NCT00620841)
- Testing
- genotyping
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- KU Leuven
Chromosomal Abnormalities
Chromosomal Analysis of Single Cells in Human Embryos
Optimise genetic screening of human embryos using higher resolution techniques
- Trial name
- NCT00614367
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Endometriosis
Effect of Anti TNFa Upon Deep Endometriosis Associated Pain
Deep endometriosis associated pain is believed to be caused by inflammation. Anti TNFa has been proved to be an effective treatment for other inflammation related conditions as Crohn's disease Endometriosis is associated with an…
- Trial name
- Infliximab (NCT00604864)
- Testing
- anti TNFa monoclonal antibody - Infliximab
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- KU Leuven
In Vitro Fertilization
Preimplantation Genetic Screening in Women Over 35 Year
In view of insufficient evidence to routinely use Preimplantation Genetic Screening (PGS) to improve success rates after IVF, we test the hypothesis that patients with advanced maternal age (AMA) have a higher implantation rate…
- Trial name
- NCT00593671
- Testing
- Preimplantation genetic screening after embryo biopsy
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Renal Transplantation
Prediction of NODAT After Renal Transplantation
A statistical analysis of the predictive value of OGTT and FPG testing executed as part of standard clinical practice after renal transplantation for the diagosis of new-onset diabetes mellitus after transplantation.
- Trial name
- NCT00442988
- Where
- Belgium
- Volunteers
- 360 people
- Sponsor
- KU Leuven
Renal Transplantation
Long-Term Pharmacokinetics of Tacrolimus in Renal Recipients
An evaluation of the effects of genetically determined variant metabolizing and transporting proteins involved in the disposition of the immunosuppressive drug tacrolimus in renal transplant recipients.
- Trial name
- NCT00411944
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- KU Leuven
Critical Illness
KULeuven Intensive Insulin Therapy Study in Medical Intensive Care Patients
In a previous study, we showed that tight blood glucose control with insulin during intensive care reduced morbidity and mortality of surgical intensive care patients.
- Trial name
- NCT00115479
- Testing
- intensive insulin therapy to maintain normoglycemia
- Where
- Belgium
- Volunteers
- 1,200 people
- Sponsor
- KU Leuven