Clinical trials: sponsored by Kafrelsheikh University
Pulpal Necrosis
Evaluation of Regenerative Endodontic Treatment for Immature Teeth
The goal of this clinical trial is to evaluate if regenerative endodontic treatment using two different forms of demineralized dentin matrix (DDM) can effectively treat immature permanent single-rooted teeth compared to treatment…
- Trial name
- NCT07210359
- Testing
- human treated dentin matrix hydrogel, Theracal LC - Demineralized dentin matrix combination, Retro Mta
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Sacubitril/Valsartan, Prosthetic Heart Valve
Sacubitril/Valsartan in Patients With Prosthetic Heart Valves With Heart Failure and Reduced Ejection Fraction
This study aims to evaluate the effect of sacubitril/valsartan in patients with prosthetic heart valves with heart failure with reduced ejection fraction (HFrEF).
- Conditions
- Sacubitril/Valsartan, Prosthetic Heart Valve, Heart Failure, Reduced Ejection Fraction
- Trial name
- NCT07192341
- Testing
- Sacubitril/Valsartan, Conventional anti-heart failure therapy
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Kafrelsheikh University
Ischemic Stroke
Combining Aspirin With Ticagrelor or Cilostazol in Large-vessel Minor Stroke or TIA
Along with the current clinical trial, the efficacy and safety of a 180 mg loading dose of ticagrelor administered within 24 hours of the first-ever large-vessel minor stroke or TIA compared to 200mg cilostazol were assessed…
- Trial name
- NCT06591377
- Testing
- Ticagrelor 90 MG, Cilostazol 100 MG, Aspirin 75mg
- Where
- 2 sites in Egypt
- Volunteers
- 900 people
- Sponsor
- Kafrelsheikh University
Ischemia Limb, Diabete Mellitus
Comparative Study of Negative-Pressure Wound Therapy Integrated With Silver Nanoparticle Spray Versus Negative-Pressure Wound Therapy in Post-Revascularization Diabetic Foot Wound Management
This was a prospective, parallel-group, randomized controlled trial conducted at the Vascular Surgery Department of Kafrelsheikh University Hospital, Egypt.
- Trial name
- SNIPS-FOOT (NCT07147790)
- Testing
- After successful revacularization, We will categorize patients into two groups : groups A (The patient's wound will be cleaned and irrigated with silver nanoparticle spray, then we will cover the woun, Silver Nanoparticles Irrigant
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kafrelsheikh University
Hand Functions on Hemiplegic Cerebral Palsy
Effect of Action Observation Training Versus Core Stability Training on Hand Functions in Children With Hemiplegic Cerebral Palsy
This study will be conducted to compare between the effectiveness of Action observation therapy (AOT) and core stability training and the combination of Action observation therapy (AOT) and core stability training on hand…
- Trial name
- NCT06930053
- Testing
- Core stability training, Action observation therapy, combination of Action observation therapy and core stability training .
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Kafrelsheikh University
Telangectasia, Reticular Veins
Foam and Liquid Sclerotherapy With or Without Herbal Gel for Small Vein Treatment
Telangiectasias (spider veins) and reticular veins represent early and common manifestations of chronic venous insufficiency . Telangiectasias are dilated intradermal venules or capillaries less than 1 mm in diameter and…
- Trial name
- ELF-HTR (NCT07162844)
- Testing
- Liquid sclerotherapy in telangectasia and reticular veins without application of herbal gel post procedure, Liquid sclerotherapy in telangectasia and reticular veins wit application of herbal gel post procedure, foam sclerotherapy in telangectasia and reticular veins without application of herbal gel post procedure
- Where
- Egypt
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Ischemic Stroke, Alteplase Adverse Reaction
Predictors of Post-alteplase Hemorrhagic Transformation of Brain Infarction
The investigators evaluated whether the characteristics of ischemic stroke patients, door-to-needle time, and stroke risk factors were predictive variables for different subtypes of post-alteplase hemorrhagic transformation of…
- Trial name
- NCT06337175
- Testing
- Alteplase
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Kafrelsheikh University
Ischemic Stroke
Combining Aspirin With Ticagrelor or Clopidogrel in Large-vessel Minor Stroke or TIA
Along with the current clinical trial, the efficacy and safety of a 180 mg loading dose of ticagrelor administered within 24 hours of the first-ever large-vessel minor stroke or TIA compared to 300 mg clopidogrel were assessed…
- Trial name
- NCT06591338
- Testing
- Ticagrelor 90 MG, Clopidogrel, Aspirin 75 Mg Oral Tablet
- Where
- Egypt
- Volunteers
- 900 people
- Sponsor
- Kafrelsheikh University
Ischemic Stroke
Combining Use of Clopidogrel With Atorvastatin or Rosuvastatin in Patients With Large-vessel Ischemic Stroke
Along with the current clinical trial, the impact of adding atorvastatin or rosuvastatin in the first 24 hours on the clinical outcomes of first-ever large-vessel ischemic stroke patients treated with clopidogrel assessed through…
- Trial name
- NCT06360120
- Testing
- Atorvastatin 40 Mg Oral Tablet, Rosuvastatin 20mg, Clopidogrel 75 Mg Oral Tablet
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Kafrelsheikh University
Androgenetic Alopecia
N-Acetyl-Cysteine for Treatment of AGA in Men
To study the effectiveness and safety of the reactive oxygen species scavenger N-acetyl-cysteine (NAC) as a single therapy and in combination with the topically applied minoxidil for the treatment of the early-onset androgenetic…
- Trial name
- NCT04209803
- Testing
- Minoxidil 5% topically and oral NAC 600 mg
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kafrelsheikh University
Dental Caries, Gingivitis
Parental Perception of Oral Health-Related Quality of Life in Sudanese Refugee vs. Egyptian Children
This cross-sectional analytical study aims to assess and compare parental perceptions of oral health-related quality of life (OHRQoL) among Sudanese refugee children and Egyptian children aged 6-12 years living in Egypt.
- Conditions
- Dental Caries, Gingivitis, Oral Health, Refugee Health
- Trial name
- NCT07011381
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Oligohydramnios
Comparison Between Treatments of Oligohydramnios
Based on previous studies, Both sildenafil and L-arginine helped to improve idiopathic oligohydramnios. In this study, Level of improvment of oligohydramnios will be compared.
- Trial name
- NCT07135037
- Testing
- Sildenafil 25 MG, L-Arginine, 1000 Mg Oral Tablet
- Where
- 2 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Upper Extremity Function In Childern With Erb's Palsy
Effect of Action Observation Therapy Versus Kinesio Taping on Upper Extremity Function In Children With Erb' Palsy
The purpose of this study is to study the Effect of Action Observation Therapy versus Kinesiology Taping on upper extremity function In Erb\'s Palsy Children.
- Trial name
- NCT06930040
- Testing
- Action observation therapy protocol, Kenisiotaping
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Kafrelsheikh University
Recession, Gingival, Bone Loss in Jaw
L-PRF vs Connective Tissue With Customized Healing Abutment in Immediate Implant Placement
comparison between L-prf and connective tissue with dental implant
- Trial name
- NCT07102758
- Testing
- L-PRF with dental implant and customized healing abutment, Connective tissue with dental implant and customized healing abutment
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Immediate Implant Placement
Effect of Albumin Platelet-Rich Fibrin or Leucocyte- Platelet-Rich Fibrin on Immediate Implant
The objective of this study will be to compare between Immediate Implant grafted with xenograft and Alb-PRF gel versus xenograft with L-PRF.
- Trial name
- NCT06863051
- Testing
- Immediate Implant Placement and Alb-PRF, Immediate Implant Placement and L-PRF
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Suit Therapy, Dual Task Exercises
Effectiveness of Suit Therapy With Dual Task Exercises on Gross Motor Functions and Walking in Children With Diplegic Cerebral Palsy
This study aims to investigate the effect of suit therapy combined with dual-task training on gross motor performance and walking abilities in children with diplegic cerebral palsy.
- Conditions
- Suit Therapy, Dual Task Exercises, Gross Motor Functions, Walking
- Trial name
- NCT07096531
- Testing
- Suit therapy, Suit therapy + Dual-task exercises
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kafrelsheikh University
Symptom Duration, Outcomes
Affection of Symptoms Duration on Outcomes of Lumbar Spine Surgery
This study aims to evaluate the affection of symptoms duration on outcomes of lumbar spine surgery.
- Conditions
- Symptom Duration, Outcomes, Lumbar Spine Surgery
- Trial name
- NCT07061067
- Testing
- Lumbar Spine Surgery
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Seroma, Lumbar Spine Decompression
Management of Seroma After Posterior Lumbar Spine Decompression
The aim of this study is to evaluate the clinical presentation and management strategies of seroma formation following posterior lumbar spine decompression.
- Trial name
- NCT07060781
- Testing
- Posterior Lumbar Spine Decompression
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kafrelsheikh University
Alveolar Socket Preservation
Post Extraction Changes After Alveolar Socket Preservation Using Autogenous Dentin Graft (ADG) Combined With Either Albumin Platelet-rich Fibrin (ALB-PRF) or Standard Platelet-rich Fibrin (PRF).
The study focuses on the impact of tooth loss on alveolar bone, which shrinks significantly within the first three months. To prevent this, strategies like alveolar ridge preservation are used.
- Trial name
- Alb-PRF (NCT06757218)
- Testing
- empty socket, Autogenous Dentin Graft with Platelet Rich Fibrin, Autogenous Dentin Graft with Albumin Platelet Rich Fibrin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Fentanyl, Dexmedetomidine
Fentanyl and Dexmedetomidine as Adjuvants to Bupivacaine in Ultrasound-guided Superficial Cervical Plexus Block in Thyroid Surgeries
This study aimed to compare the analgesic efficacy between fentanyl and dexmedetomidine as adjuvants to bupivacaine in ultrasound-guided superficial cervical plexus block for thyroid surgeries.
- Conditions
- Fentanyl, Dexmedetomidine, Adjuvants, Bupivacaine
- Trial name
- NCT07057739
- Testing
- Superficial cervical plexus block, Superficial cervical plexus block + Fentanyl, Superficial cervical plexus block + Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University