Clinical trials: sponsored by Kaiser Permanente
Breast Cancer
Implementing Systematic Distress Screening in Breast Cancer
Many breast cancer patients experience psychological distress during their cancer care journey. There are effective treatments for breast cancer patients experiencing distress, such as individual or group therapy, health…
- Trial name
- NCT02941614
- Testing
- Distress screening
- Where
- 6 sites in United States
- Volunteers
- 1,436 people
- Sponsor
- Kaiser Permanente
Insomnia
Trial of Internet-Based Cognitive Behavioral Therapy for Insomnia
The investigators will conduct a randomized, controlled trial of internet-based cognitive behavioral therapy (iCBT) vs usual care for insomnia.
- Trial name
- NCT03313466
- Testing
- Internet cognitive behavioral therapy for insomnia (iCBTI), Class in sleeping well and improving insomnia
- Where
- United States
- Volunteers
- 136,630 people
- Sponsor
- Kaiser Permanente
Gestational Weight Gain
Appropriate Gestational Weight Gain in Overweight/Obese Women
The goal of this trial is to investigate the efficacy of a lifestyle intervention of healthy diet and physical activity for helping overweight/obese pregnant women to achieve appropriate gestational weight gain (GWG) for their…
- Trial name
- NCT02130232
- Testing
- Lifestyle Intervention, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 398 people
- Sponsor
- Kaiser Permanente
Depression, Preterm Delivery
Comparing Effectiveness of Treating Depression With & Without Comorbidity to Improve Fetal Health
Depression during pregnancy is prevalent (15-20%) and has an adverse impact on fetal outcomes including preterm delivery (PTD) and low birthweight (LBW).
- Trial name
- PCORIPTD (NCT02371356)
- Volunteers
- 91,084 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Prolapse of Vaginal Vault After Hysterectomy
Prophylactic Uterosacral Ligament Suspension at the Time of Hysterectomy for Prevention of Vaginal Vault Prolapse
Is routine uterosacral ligament suspension an appropriate clinical adjunct at the time of hysterectomy? The answers to these questions will facilitate the treatment of many American women.
- Trial name
- NCT01364025
- Testing
- uterosacral ligament suspension colpopexy bilateral
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Kaiser Permanente
Cancer, Chronic Obstructive Pulmonary Disease
Comparative Trial of Home-Based Palliative Care
Background: To effectively alleviate suffering and improve quality of life for patients with serious illness and their caregivers, palliative care (PC) services must be offered across multiple settings.
- Conditions
- Cancer, Chronic Obstructive Pulmonary Disease, Heart Failure, Dementia
- Trial name
- HomePal (NCT03694431)
- Testing
- Tech-supported HBPC, Standard HBPC
- Where
- 2 sites in United States
- Volunteers
- 3,999 people
- Sponsor
- Kaiser Permanente
Chronic Obstructive Pulmonary Disease (COPD)
Walk On! Physical Activity Coaching
Chronic obstructive pulmonary disease (COPD) is the third leading cause of the death in the US. The personal, social and economic costs of the disease are tremendous, with annual expenditures of nearly $50 billion, mostly from…
- Trial name
- NCT02478359
- Testing
- Physical Activity Coaching (Walk On!)
- Where
- United States
- Volunteers
- 2,707 people
- Sponsor
- Kaiser Permanente
Obesity
A Randomized Trial Comparing Two Doses of Portion-Controlled Foods Within a Primary Care Weight Loss Program
We hypothesize that individuals provided with 1 meal per day of portion-controlled foods (shakes and prepared entrees) will lose as much weight as individuals provided with 2 meals per day of portion-controlled foods.
- Trial name
- PCPCWLS (NCT00907660)
- Testing
- Weight loss counseling, Portion-Controlled Foods
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Kaiser Permanente
Obesity
Adaptation of the Diabetes Prevention Program for Primary Care
The study has two primary aims. The first aim is to assess the efficacy of adding in-person visits to the use of portion-controlled foods for long-term weight loss.
- Trial name
- NCT01220089
- Testing
- Standard maintenance, Intensified maintenance
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Esophageal Cancer
Assessment of a Modified Minimally Invasive Esophagectomy
This is a retrospective case series of a novel fully minimally invasive esophagectomy procedure for patients with primary esophageal cancer.
- Trial name
- NCT04219410
- Testing
- Fully minimally invasive esophagectomy
- Volunteers
- 142 people
- Sponsor
- Kaiser Permanente
Arthritis Knee
Feasibility of Multi-modal Physical Therapy in Latino Older Adults With Moderate Knee Osteoarthritis
This is a small, pilot, pre/post evaluation study enrolling older Hispanic American adults with moderate knee arthritis to evaluate the feasibility of recruitment, retention and adherence after a multimodal 12-week, physical…
- Trial name
- NCT04219423
- Testing
- Multimodal physical therapy
- Volunteers
- 20 people
- Sponsor
- Kaiser Permanente
PreDiabetes, Obesity
Comparison of Outreach Methods to Encourage Enrollment in Diabetes Prevention and Weight Management Programs
Individuals with prediabetes are at increased risk for developing diabetes. Higher hemoglobin A1c's (6.1-6.4%) are associated with a high risk of developing diabetes.
- Trial name
- NCT03200535
- Testing
- EHR gaps, Bulk outreach, Dietician call
- Where
- United States
- Volunteers
- 6,588 people
- Sponsor
- Kaiser Permanente
Chest Pain, Coronary Artery Disease
PROMISE Substudy to Assess For Effective Dose of Radiation (PROMISE-SAFER) Specific Aim 3b
The purpose of this study is to compare different methods of collecting the amount of radiation exposure patients receive in a clinical study.
- Conditions
- Chest Pain, Coronary Artery Disease, Angina
- Trial name
- PROMISE-SAFER (NCT01890525)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kaiser Permanente
Colorectal Cancer
Financial Incentives to Increase Colorectal Cancer Screening in Priority Populations
The investigators propose to build on the success of the Systems of Support to Increase Colorectal Cancer trial (SOS, R01CA121125, Green) and focus on disparity groups who are less likely to be current for colorectal cancer (CRC)…
- Trial name
- NCT03080701
- Testing
- Auto Mailing Plus Money, Auto Mailing Plus Lottery
- Where
- United States
- Volunteers
- 898 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Chronic Pain
Patient Activation to Address Chronic Pain and Opioid Management in Primary Care
Will a primary care-based behavioral intervention for patient activation and engagement and self-management, for patients with chronic pain who are taking opioid pain medication, result in better patient outcomes than Usual Care?
- Trial name
- NCT02290223
- Testing
- Behavioral Based Treatment Model
- Where
- 2 sites in United States
- Volunteers
- 376 people
- Sponsor
- Kaiser Permanente
Oral Disease, Smoking
Promoting Oral Health Among Smokers Randomized Trial
The current study will test the effectiveness of a multi-modal behavioral intervention (the Oral Health 4 Life program) targeted to smokers who are ready to quit smoking and seeking services through tobacco quitlines.
- Trial name
- NCT02347124
- Testing
- Usual Care Control, Enhanced Intervention
- Where
- United States
- Volunteers
- 718 people
- Sponsor
- Kaiser Permanente
Low Back Pain
Efficacy of Acupuncture for Chronic Low Back Pain
This is a trial to clarify the extent to which acupuncture needling can diminish the effect of chronic back pain on patient functioning and symptoms.
- Trial name
- NCT00065585
- Testing
- Accupuncture
- Where
- 2 sites in United States
- Volunteers
- 640 people
- Sponsor
- Kaiser Permanente
Opiate Substitution Treatment
Buprenorphine and Substance Abuse Services for Prescription Opioid Dependence
This is a randomized trial of two group-based models of care for buprenorphine/naloxone (bup/nx) patients in Substance Use (SU) specialty treatment: Standard Medical Management (SMM) and Intensive Outpatient Treatment (IOT).
- Trial name
- NCT02496403
- Testing
- Standard Medical Management (SMM)
- Where
- United States
- Volunteers
- 239 people
- Sponsor
- Kaiser Permanente
Cardiovascular Disease, Essential Hypertension
The Northwest Coalition for Primary Care Practice Support
The purpose of this project is to build capacity for quality improvement (QI) in small primary care practices across Washington, Oregon and Idaho by improving risk factors for heart attacks such as blood pressure, cholesterol and…
- Conditions
- Cardiovascular Disease, Essential Hypertension, Nicotine Dependence, Hyperlipidemia
- Trial name
- H2N (NCT02839382)
- Testing
- Coaching, Educational Outreach, Site Visits
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- Kaiser Permanente
Alcohol Use Disorder
Considering Healthier Drinking Options in Collaborative Care
The purpose of this study is to evaluate the effectiveness of a collaborative care intervention for evidence based management of alcohol use disorders in primary care settings within the Veterans Administration Puget Sound Health…
- Trial name
- CHOICE (NCT01400581)
- Testing
- Collaborative Care Intervention
- Where
- United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente