Clinical trials: sponsored by Kaiser Permanente
Gestational Diabetes
Lifestyle Intervention Program for Women With Gestational Diabetes or Gestational Impaired Glucose Tolerance
The purpose of this research study is to implement and evaluate a lifestyle program designed to help women who have high glucose levels during pregnancy make healthful diet and physical activity changes to lose weight.
- Trial name
- APPLES (NCT01489163)
- Testing
- Lifestyle Counseling
- Where
- United States
- Volunteers
- 352 people
- Sponsor
- Kaiser Permanente
Pregnancy, Gestational Diabetes
Role of Liver and Visceral Fat in Glucose and Lipid Metabolism During Pregnancy
Obesity, increased abdominal fat, fat stored in the liver, and insulin resistance may all be associated with adverse maternal and fetal pregnancy outcomes.
- Conditions
- Pregnancy, Gestational Diabetes, Obesity, Liver Fat
- Trial name
- NCT02282475
- Volunteers
- 78 people
- Sponsor
- Kaiser Permanente
Cancer
CHOICES: Understanding Clinical Trials as a Treatment Option
The goal of this study is to determine whether having a telephone discussion with a nurse educator about making treatment decisions and participating in a clinical trial increases trial participation.
- Trial name
- CHOICES (NCT00983866)
- Testing
- Tailored Telephone Counseling
- Where
- United States
- Volunteers
- 1,376 people
- Sponsor
- Kaiser Permanente
Insomnia, Depression
CBT Insomnia Teens: Augmenting SSRIs to Improve Youth Depression
This study is a randomized controlled trial that tests the effectiveness of cognitive behavior therapy (CBT) for insomnia with comorbid depression in youth aged 12 through 19 who have recently begun selective serotonin re-uptake…
- Trial name
- SleepWell (NCT02290496)
- Testing
- CBT for Insomnia (CBT-I), Sleep Hygiene (SH)
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Kaiser Permanente
Stroke
An Evaluation of Clinical Pharmacist-led Intervention on Clinical Outcomes in Patients With Ischemic Stroke
Clinical pharmacy specialists are in an ideal position to assist medical teams in the management of patients with ischemic stroke.
- Trial name
- NCT01876667
- Testing
- Intervention (CPCRS) Group
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Kaiser Permanente
Physical Activity
A Micro-randomized Trial of HeartSteps, an mHealth Intervention for Increasing Physical Activity
The aim of this research is to evaluate the efficacy of contextually tailored activity suggestions and activity planning for increasing physical activity among sedentary adults.
- Trial name
- HS (NCT03225521)
- Testing
- HeartSteps: A just-in-time adaptive intervention for increasing physical activity amongst sedentary adults.
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Diabetes, Heart Disease
The CREATE Wellness Study
Cardiovascular disease (CVD) is the leading cause of death in the U.S. Efforts to improve CVD risk factors often fall short in complex patients with multiple co-morbid conditions, a growing, expensive, and high-risk segment of…
- Conditions
- Diabetes, Heart Disease, Hypertension, Dyslipidemia
- Trial name
- NCT02302612
- Testing
- CREATE Wellness, Usual Care Control
- Where
- United States
- Volunteers
- 647 people
- Sponsor
- Kaiser Permanente
Diabetes Mellitus, Type 2, Overweight
Getting in Balance: A Workplace Diabetes Prevention Intervention Trial
This study evaluates two group-based Diabetes Prevention Program (DPP) lifestyle interventions delivered in the workplace to individuals at risk for pre-diabetes: 1) an in-person group-based lifestyle intervention; and 2) an…
- Conditions
- Diabetes Mellitus, Type 2, Overweight, Obesity
- Trial name
- GIBW (NCT02589873)
- Testing
- In-Person Diabetes Prevention Program, Online Diabetes Prevention Program
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Hematopoietic Stem Cell Transplantation
Ledipasvir/Sofosbuvir Treatment for Hepatitis C in HCT Recipients.
The prevalence of Hepatitis C Virus (HCV) infection was reported to range between 10% and up to 30% prior to institution of routine HCV screening in recipients of HCT (hematopoietic cell transplantation).
- Trial name
- NCT03279133
- Testing
- Ledipasvir 90mg/Sofosubvir 400mg
- Where
- 2 sites in United States
- Sponsor
- Kaiser Permanente
Stroke, Hemiplegia
E-Rehabilitation: Aerobic Resistance Training for Stroke Survivors
This pilot study intends to evaluate an online exercise video rehabilitation program for stroke survivors with moderate disability compared to usual care.
- Trial name
- NCT02938000
- Testing
- Theraband with exercise video, usual care with advice to exercise
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Kaiser Permanente
Smoking
Proactive Health Intervention for Tobacco Users (Get PHIT)
The goal of this study is to understand how information about smokers' health risks affects their attitudes, mood, and behavior.
- Trial name
- NCT00169260
- Testing
- motivational counseling
- Where
- United States
- Volunteers
- 536 people
- Sponsor
- Kaiser Permanente
HIV Infections
Evaluating the Effect of CHanging EnfuvirtidE to Raltegravir in HIV Infected Subjects
The primary objective of this study is: To assess the virologic effect of changing enfuvirtide to MK-0518(raltegravir) in human immunodeficiency virus type 1(HIV-1) infected patients who have an undetectable level of serum human…
- Trial name
- CHEER (NCT00529243)
- Testing
- raltegravir
- Where
- 8 sites in United States
- Volunteers
- 52 people
- Sponsor
- Kaiser Permanente
Pancreatitis
Pancreatic Duct Stenting to Prevent Postoperative Pancreatic Fistula (POPF) After Distal Pancreatectomy
To determine whether pre-operative pancreatic stenting for distal pancreatectomy will impact the incidence of a post-operative pancreatic fistula, as defined by postoperative.
- Trial name
- NCT02573389
- Testing
- Boston Scientific or Cook pancreatic duct stents
- Volunteers
- 120 people
- Sponsor
- Kaiser Permanente
HIV
Community-based Interventions to Increase HIV Testing and HIV Care Utilization
The purpose of this study is to conduct a cross-site evaluation of the Kaiser Permanente's Community-based Interventions to Increase HIV Testing and HIV Care Utilization Program, designed to support community-based interventions…
- Trial name
- NCT01867177
- Testing
- HIV testing, standard of HIV care, HIV care utilization
- Where
- United States
- Volunteers
- 583 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Pulmonary Embolism
Electronic Support for Pulmonary Embolism Emergency Disposition
To evaluate the impact of an integrated electronic clinical decision support system to facilitate risk stratification and site-of-care decision-making for patients with acute pulmonary embolism.
- Trial name
- eSPEED (NCT03601676)
- Testing
- Integration of electronic clinical decision support
- Where
- 14 sites in United States
- Volunteers
- 1,703 people
- Sponsor
- Kaiser Permanente
HIV Infections
Investigator-Sponsored Protocol - Continued Use of Ibalizumab
This protocol serves to extend the successful treatment for HIV positive patients beyond the endpoints provided by the Phase 2b TaiMed Biologics-sponsored protocol TMB202 (entitled "A Phase 2b Randomized, Double-Blinded, 48-Week…
- Trial name
- NCT01056393
- Testing
- ibalizumab 800mg Q2Weeks, ibalizumab 2000mg Q4Weeks
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Kaiser Permanente
Obesity, Sedentary Lifestyle
I-STAND R21: Reducing Sedentary Time in Older Adults
The investigators are doing a study to learn how to support patients aged 60+ in taking more breaks from sitting and reducing total sitting time.
- Trial name
- NCT02692560
- Testing
- I-STAND, Healthy Living
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kaiser Permanente
Diabetic Peripheral Neuropathy
Balancing Treatment Outcomes and Medication Burden Among Patients With Symptomatic Diabetic Peripheral Neuropathy
Painful diabetic peripheral neuropathy (DPN) affects more than 5.5 million people with diabetes. People with painful DPN have trouble sleeping, participating in social events, and conducting daily activities such as going to the…
- Trial name
- NCT02056431
- Testing
- IVR Intervention Group
- Where
- United States
- Volunteers
- 1,270 people
- Sponsor
- Kaiser Permanente
Peritoneal Dialysis Complication, Hypoalbuminemia
The Effect of Natural Protein vs. Protein Supplements on Peritoneal Dialysis Patients
This study is a prospective open label clinical trial comparing serum albumin levels and total protein intake in the peritoneal dialysis patient population.
- Conditions
- Peritoneal Dialysis Complication, Hypoalbuminemia, Malnutrition
- Trial name
- NCT03569410
- Testing
- increased protein intake via natural foods, increase protein intake via protein supplements
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Tennis Elbow, Lateral Epicondylitis
Multiple Platelet-Rich Plasma Lateral Epidondylitis Injections Versus a Single Platelet-Rich Plasma Injection
To determine the ideal dose of PRP for lateral epicondylitis. To see if 2 PRP injections are better than a single PRP injection or a saline injection to improve function and pain in patients with lateral epicondylitis.
- Trial name
- PRPLE (NCT02343822)
- Testing
- Platelet Rich Plasma Injection, Saline Injection
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente