Clinical trials: sponsored by Kaiser Permanente
Colorectal Cancer, Colorectal Polyp
Predicting Risk for Post-polypectomy Colorectal Cancer
This originated as an observational study of Kaiser Permanente Northern California (KPNC) patients with a history of adenoma diagnosed by colonoscopy who received a subsequent surveillance colonoscopy between 2014 and 2019.
- Conditions
- Colorectal Cancer, Colorectal Polyp, Colorectal Adenoma, Neoplasm, Colorectal
- Trial name
- PREDICT (NCT05606081)
- Testing
- Logistic regression risk model
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Tobacco Use Disorder, Smoking Cessation
Development of a mHealth Intervention for Ambivalent Smokers
The current pilot study will assess the feasibility and acceptability of a novel mHealth app designed for people who are ambivalent about quitting smoking.
- Conditions
- Tobacco Use Disorder, Smoking Cessation, Motivation, Behavior, Smoking
- Trial name
- NCT04560868
- Testing
- Control mHealth program, Experimental mHealth program, Nicotine patch
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Diabetes Mellitus, Cardiovascular Disease
SPREAD-NET: PRactices Enabling Adapting and Disseminating in the Safety NET
The investigators propose to compare the effectiveness of 3 strategies (low, medium, high intensity) at supporting CHCs' implementation of the ALL Initiative (an intervention shown to reduce patients' cardiovascular disease (CVD)…
- Trial name
- SPREAD-NET (NCT02325531)
- Testing
- Low support, Medium support, High support
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Diabetes
Addressing Social Determinants of Health & Diabetes Self-Management in Vulnerable Populations
In this pilot and feasibility study, the investigator will randomize 100 African-American, Hispanic, and/or Medicaid (all race/ethnicities) patients from KPNW with A1C ≥ 8 to one of two 6-month interventions: 1) patient…
- Trial name
- NCT03802825
- Testing
- Diabetes Self-Management Training, Standard Patient Navigation
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Postoperative Urinary Tract Infection, Pelvic Organ Prolapse
Gentamicin Intravesical Efficacy for Infection of Urinary Tract
Urinary tract infection (UTI) is a common problem after surgery for pelvic organ prolapse and stress urinary incontinence. This prospective, randomized, single-masked (subject), two-parallel armed study aims to determine the…
- Conditions
- Postoperative Urinary Tract Infection, Pelvic Organ Prolapse, Stress Urinary Incontinence
- Trial name
- GIVEIT (NCT04246996)
- Testing
- gentamicin sulfate, Catheter clamping only
- Where
- 2 sites in United States
- Volunteers
- 370 people
- Sponsor
- Kaiser Permanente
Resistance Training, Colon Cancer
FOcus on Reducing Dose-limiting Toxicities in Colon Cancer With Resistance Exercise Study
FORCE is a randomized home-based resistance training/strength training (RT) intervention study for Stage II and III colon cancer patients undergoing chemotherapy.
- Conditions
- Resistance Training, Colon Cancer, Chemotherapy Effect
- Trial name
- FORCE (NCT03291951)
- Testing
- Resistance training
- Where
- 3 sites in United States
- Volunteers
- 183 people
- Sponsor
- Kaiser Permanente
Diabetes
Evaluating the Implementation of the Diabetes Prevention Program in an Integrated Health System
In preparation for the roll out of the Medicare Diabetes Prevention Program (DPP) in 2018, Kaiser Permanente Northwest (KPNW), a large, integrated health care system, plans to pilot the implementation of DPP starting in April…
- Trial name
- NCT03249077
- Testing
- Digital DPP, In-person DPP, DPP not enrolled
- Where
- United States
- Volunteers
- 8,198 people
- Sponsor
- Kaiser Permanente
Chronic Pain
Escoge Salud (Choose Health): a Chronic Pain Self-Management Program in Middle to Older Age Hispanic Americans
The purpose of this study is to evaluate patient satisfaction and health status before and after a 6-week established self-management training program for middle to older age Hispanic Americans living with chronic musculoskeletal…
- Trial name
- NCT04554576
- Testing
- Chronic Disease Self-Management Program (CDSMP) for chronic pain in Spanish, Remote feedback active group, Remote feedback control group
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Kaiser Permanente
Hypertension
Discovering Healthcare Innovations to Address Disparities in Stroke (DIADS)
The goal of this pragmatic study is to improve hypertension (HTN) control rate in blacks and to reduce racial disparity in HTN control.
- Trial name
- DIADS (NCT01892592)
- Testing
- Diet and Lifestyle
- Where
- United States
- Volunteers
- 1,761 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Covid19
Low-Dose Chest CT (LDCT) COVID-19 Study
The goal of our proposed pilot study is to collect low dose CT (LDCT) findings from chest evaluations of a representative sample of 120 symptomatic Caucasian and African American, and Hispanic adults (45 each), stratified by…
- Trial name
- NCT05031845
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Kaiser Permanente
Overweight, Obese
PREPARE: A Randomized Trial of a Pre-pregnancy Weight Loss Intervention
The US obesity epidemic is being transmitted to the next generation. Growing evidence suggests that both a mothers' weight at pregnancy onset, and excessive weight gain during pregnancy, are associated with increased risk of…
- Trial name
- NCT02346162
- Testing
- Weight management, Usual Care Control
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Colorectal Cancer
Participatory Research to Advance Colon Cancer Prevention
The overall goal of this study is to test strategies to raise rates of colorectal cancer screening among the Latino population in a federally qualified health center that operates multiple clinics.
- Trial name
- PROMPT (NCT03167125)
- Testing
- Automated Prompts, Automated Plus Live Prompts
- Where
- United States
- Volunteers
- 27,580 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Suicide and Self-harm
A Randomized Control Trial of a Digital Health Tool
This randomized trial evaluated whether sending population-based invitation messages through the electronic health record to visit Lock to Live (L2L), a web-based decision aid that incorporates patients' values into…
- Trial name
- L2L (NCT05288517)
- Testing
- Lock to Live
- Where
- United States
- Volunteers
- 20,131 people
- Sponsor
- Kaiser Permanente
Cardiovascular Diseases, NSTEMI
Cholesterol Lowering Via Bempedoic Acid/Ezetimibe, an ACL-Inhibiting Regimen in Acute Coronary Syndrome Study
The overall objective of the Cholesterol Lowering via Bempedoic Acid/Ezetimibe, an ACL-Inhibiting Regimen in Acute Coronary Syndrome ACS (CLEAR ACS) study is to determine the efficacy, safety, and tolerability of bempedoic…
- Conditions
- Cardiovascular Diseases, NSTEMI, STEMI
- Trial name
- NCT05263778
- Testing
- Bempedoic Acid / Ezetimibe Oral Tablet
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Kaiser Permanente
Gastrointestinal Disease
Optimizing Gastrointestinal Procedure Appointments
This project will address the question: Does an "enhanced" IVR-T protocol differ in effectiveness from the standard IVR-T protocol in reducing missed appointments and late cancellations for GI endoscopy? Hypothesis: The enhanced…
- Trial name
- NCT03879616
- Testing
- An Enhanced Reminder
- Where
- United States
- Volunteers
- 15,974 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Decrease Variability and Amount of Radiation Dose From CT Exams
Radiation Dose Audit Reports to Reduce Radiation Exposure From CT Exams
The purpose of this study is to quantify variation in radiation dose levels across CT technologists, and determine the effectiveness of combining radiation dose audit reports and an educational seminar as a means to reduce the…
- Trial name
- NCT01405066
- Testing
- Radiation Dose Audit Reports, Educational Seminar: Radiation Dose Reduction
- Volunteers
- 19 people
- Sponsor
- Kaiser Permanente
Heart Failure, Copd
Meals MATTER: A Trial of Medically Tailored Meals 2 Weeks vs. 4 Weeks Post Hospital Discharge
The purpose of this study is to determine if medically tailored meals provided for either 2 weeks or 4 weeks (1 meal per day) to a Kaiser Permanente Colorado (KPCO) member after hospital discharge will improve their health.
- Conditions
- Heart Failure, Copd, Liver Failure, Diabetes Mellitus
- Trial name
- NCT04351880
- Testing
- Medically Tailored Meals
- Where
- 2 sites in United States
- Volunteers
- 650 people
- Sponsor
- Kaiser Permanente
Shock
Extension of the RUSH Protocol for Volume Responsiveness
The current study plants to create a patient registry of patients who present to the emergency department with signs and symptoms of shock and evaluate the ability of a multi-step cardiopulmonary ultrasound protocol to determine…
- Trial name
- NCT03285269
- Testing
- Ultrasound Protocol, Bioreactance, Passive Leg Raise
- Sponsor
- Kaiser Permanente
Obesity, Childhood Obesity
PsylliumRx Dietary Fiber Study
The purpose of this pilot study is to assess the feasibility of a 3-month dietary fiber intervention: 1) engaging adolescents in regularly consuming a dietary fiber preparation (psyllium powder) and obtaining their parents'…
- Trial name
- NCT03629119
- Testing
- Dietary Fiber Supplement
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Depression, Social Media
Social Media Use in Adolescents Admitted to a Psychiatric Unit
We will investigate the association between social media use and depression in adolescents admitted to a psychiatric unit and continue to follow their progress after discharge in outpatient clinic services.
- Conditions
- Depression, Social Media, Adolescent Behavior
- Trial name
- NCT03836846
- Testing
- CBT Mobile App, Treatment as usual
- Where
- United States
- Sponsor
- Kaiser Permanente