Clinical trials: sponsored by Kaiser Permanente
Type 2 Diabetes Mellitus With Hypoglycemia, Aging
Prepare for Your Diabetes Care
As adults with type 2 diabetes age, they are increasingly vulnerable to treatment-related hypoglycemia and its related complications (including hospitalization and death).
- Conditions
- Type 2 Diabetes Mellitus With Hypoglycemia, Aging, Patient Activation
- Trial name
- NCT05263310
- Testing
- Prepare for Your Diabetes Care, Usual Care
- Where
- United States
- Volunteers
- 672 people
- Sponsor
- Kaiser Permanente
Drug Use Disorders, Illicit Drug Use
Addressing Barriers to Care for Substance Use Disorder Pilot Study
The Addressing Barriers to Care for Substance Use Disorder Pilot (ABC-SUD Pilot) was a randomized pilot study that preceded a larger trial.
- Conditions
- Drug Use Disorders, Illicit Drug Use, Alcohol-Related Disorders
- Trial name
- ABCSUD Pilot (NCT06317987)
- Testing
- Care Navigation
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Kaiser Permanente
Gestational Weight Gain
A Mobile Health Intervention to Achieve Appropriate Gestational Weight Gain in Overweight/Obese Women
The aim of this trial is to investigate the effectiveness of a mobile health (mhealth) intervention to help overweight and obese women achieve appropriate gestational weight gain (GWG) for their pre-pregnancy body mass index…
- Trial name
- NCT03880461
- Testing
- Lifestyle Intervention
- Where
- 4 sites in United States
- Volunteers
- 1,335 people
- Sponsor
- Kaiser Permanente
Latent Tuberculosis
Brief Educational Video for Patients Prescribed LTBI Treatment
Many patients who are prescribed treatment for latent tuberculosis (LTBI) do not complete treatment. Effective interventions that are low-cost and feasible for large-scale implementation are needed to support efforts to eliminate…
- Trial name
- NCT05412212
- Testing
- LTBI video intervention
- Where
- United States
- Volunteers
- 1,894 people
- Sponsor
- Kaiser Permanente
Dementia, Alzheimer Disease
The Brain Health Study: A Pragmatic, Patient-Centered Trial
The eRADAR Brain Health Study seeks to refine and test a novel, low-cost strategy for increasing dementia detection within primary care.
- Trial name
- NCT05356702
- Testing
- Brain Health Assessment
- Where
- 5 sites in United States
- Volunteers
- 3,417 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Pediatric Cancer, Animal-Assisted Activities
Helping Improve Pediatric Patient Outcomes
This study involves two distinct activities: The first is a randomized controlled trial (RCT) to assess the efficacy and safety of therapy dog visits for children with cancer.
- Trial name
- HIPPO (NCT03471221)
- Testing
- Therapy Dog Visit
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Kaiser Permanente
Opioid-use Disorder
PRimary Care Opioid Use Disorders Treatment (PROUD) Trial
Effective treatment for opioid use disorders (OUDs) requires medications. Two medications for treating OUDs-buprenorphine and injectable naltrexone-can be prescribed in primary care (PC).
- Trial name
- PROUD (NCT03407638)
- Testing
- PROUD Intervention
- Where
- 6 sites in United States
- Volunteers
- 377,373 people
- Sponsor
- Kaiser Permanente
Depression
Outreach to Reduce Depression Disparities
Previous research by Mental Health Research Network (MHRN) investigators and others demonstrates that online messaging and other telehealth technologies can effectively and efficiently address premature discontinuation of…
- Trial name
- NCT05580406
- Testing
- Outreach messaging
- Where
- 2 sites in United States
- Volunteers
- 309 people
- Sponsor
- Kaiser Permanente
Pleural Effusion
Tenecteplase (TNK) for Loculated Pleural Effusions in Patients With Malignancy
The objective of the study is to determine the safety and efficacy of TNK infusion for the treatment of loculated pleural effusions in patients with known malignancy compared to normal saline infusion.
- Trial name
- NCT01580618
- Testing
- normal saline, TNK (Tenecteplase)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kaiser Permanente
Drug Use Disorders, Illicit Drug Use
Digital Treatments for Opioids and Other Substance Use Disorders in Primary Care
The DIGITS Trial addresses a critical knowledge gap: How to best implement digital treatments for opioids and other substance use disorders in primary care.
- Conditions
- Drug Use Disorders, Illicit Drug Use, Alcohol-Related Disorders, Opioid Use Disorder
- Trial name
- DIGITS (NCT05160233)
- Testing
- Standard implementation, Health Coaching, Practice Facilitation
- Where
- United States
- Volunteers
- 18,430 people
- Sponsor
- Kaiser Permanente
Diabetes Mellitus
ASCEND: ApproacheS to CHC ImplEmeNtation of SDH Data Collection and Action
This work will test a set of strategies for helping community health centers (CHCs) routinely identify and take action on the SDH-related needs of patients with / at risk for DM using a stakeholder-driven process to develop…
- Trial name
- ASCEND (NCT03607617)
- Testing
- SDH Tool
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Chronic Pain
Tailored Non-Pharmacotherapy Services for Chronic Pain
The RESOLVE study is a multicenter comparative effectiveness trial of two cognitive behavioral therapy-based chronic pain (CBT-CP) treatments delivered via telehealth modalities: 1) online program and 2) live, health coach-led…
- Trial name
- RESOLVE (NCT04523714)
- Testing
- Online CBT-CP based program, Virtual health coach-led CBT-CP based program
- Where
- 4 sites in United States
- Volunteers
- 2,333 people
- Sponsor
- Kaiser Permanente
Chronic Low-back Pain
Acupuncture for Chronic Low Back Pain in Older Adults
The main goal of the BackInAction research study is to determine the effectiveness of a standard course of acupuncture (15 sessions of acupuncture over 3 months) and an enhanced course of acupuncture (an additional 6 sessions of…
- Trial name
- BackInAction (NCT04982315)
- Testing
- Standard Acupuncture, Enhanced Acupuncture
- Where
- 4 sites in United States
- Volunteers
- 807 people
- Sponsor
- Kaiser Permanente
Colon Cancer
Study of Colorectal Cancer Screening Options
The investigators propose to evaluate Guardant Health's commercially available colorectal cancer screening assay(Guardant SHIELD) in individuals who are not up to date with CRC screening.
- Trial name
- NCT05987709
- Testing
- GuardantSHIELD Blood Test
- Where
- United States
- Volunteers
- 2,004 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Type 2 Diabetes Mellitus, Cardiovascular Diseases
Comparison of Type 2 Diabetes Pharmacotherapy Regimens
This study is designed to help patients with type 2 diabetes and their clinicians: (a) identify which glucose lowering medications have the most favorable effects on heart health and other patient-important outcomes, (b) inform…
- Trial name
- ON TARGET DM (NCT05073692)
- Testing
- SU, DPP4, SGLT2i
- Where
- 6 sites in United States
- Volunteers
- 241,981 people
- Sponsor
- Kaiser Permanente
COVID-19 Testing
COVID-19 Antibody and Reinfection Study
The goal of this study is to establish a cohort of Kaiser Permanente Colorado (KPCO) members who have and have not had COVID-19 infection for serial antibody testing and PCR testing to: 1.
- Trial name
- NCT05365750
- Where
- United States
- Volunteers
- 4,235 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Hereditary Cancer Syndrome
Cancer Health Assessments Reaching Many
The CHARM (Cancer Health Assessment Reaching Many) study will assess the utility of clinical exome sequencing and how it affects care in diverse populations.
- Trial name
- CHARM (NCT03426878)
- Testing
- Modified genetic counseling, Traditional genetic counseling
- Where
- 2 sites in United States
- Volunteers
- 967 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Postpartum Depression
Postpartum Wellness
The purpose of this study is to test whether a web-based (eHealth) exercise intervention for new moms at increased risk for postpartum depression increases physical activity and decreases postpartum depression symptoms.
- Trial name
- POW (NCT04414696)
- Testing
- Exercise intervention
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Kaiser Permanente
Drug Use Disorders, Illicit Drug Use
An Initial Study of the Implementation of Digital Therapeutics for Substance Use Disorders in Primary Care
The DIGITS Trial addresses a critical knowledge gap: How to best implement digital treatments for opioids and other substance use disorders in primary care.
- Conditions
- Drug Use Disorders, Illicit Drug Use, Alcohol-Related Disorders
- Trial name
- DIGITS Pilot (NCT04907045)
- Testing
- Health Coaching, Practice Facilitation, Standard Implementation
- Where
- United States
- Volunteers
- 1,552 people
- Sponsor
- Kaiser Permanente
Mental Health
Novel Methods for Implementing Measurement-Based Care for Youth in Low-resource Environments
This study will visit 4 community mental health clinics in Washington state and work with clinic staff to find out if staff are regularly evaluating clinical outcomes using questionnaires (which is also called measurement-based…
- Trial name
- NIMBLE (NCT05644756)
- Testing
- IMPACT Methods to Identify and Prioritize Determinants (Challenge I), Challenge and Match strategies to Prioritized Determinants (Challenge II)
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente