Clinical trials: sponsored by Kessler Foundation
Traumatic Brain Injury
Robotic Balance Training to Improve Postural Control and Balance Post-Traumatic Brain Injury
The purpose of this study is to assess a balance training program to see if it can be helpful to improve balance and avoid falls in people who have had traumatic brain injuries (TBIs).
- Trial name
- NCT06184295
- Testing
- TBI - Intervention Group
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Mild Cognitive Impairment
Cognitive Integrated Motor Training (CM) to Improve Gait and Balance and Reduce Falls in Older Adults With Mild Cognitive Impairment
Problems with walking and balance are common in older adults with mild cognitive impairment. Walking and balance problems limit independence and increase risk for injuries due to falls.
- Trial name
- CM (NCT06719297)
- Testing
- Personalized cognitive-sensorimotor VR/MR training, Standard of Care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury
Personalized Cognitive Integrated Motor Training Using Virtual Reality to Improve Gait and Balance
Problems with walking and balance are common after traumatic brain injury (TBI). Walking and balance problems limit independence and increase risk for injuries due to falls.
- Trial name
- CMT (NCT06473987)
- Testing
- Personalized cognitive-sensorimotor VR/AR training, Traditional dual-task training, Standard of Care
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Kessler Foundation
Spinal Cord Injury, Spinal Cord Disease
Paired Spinal Cord and Peripheral Nerve Stimulation to Recover Hand Function in SCI
Individuals who suffer a spinal cord injury in the neck region have difficulty using their hands due to paralysis and/or weakness of their arms and hand muscles.
- Conditions
- Spinal Cord Injury, Spinal Cord Disease, Spinal Cord Injuries (SCI)
- Trial name
- NCT06698224
- Testing
- Spinal cord transcutaneous stimulation, Paired spinal cord and peripheral nerve stimulation
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Traumatic Brain Injury, Major Depressive Disorder
MRI Markers of Feedback Timing During Learning in Individuals with TBI with and Without Clinical Depression
The goal of this proposal is to examine the influence of feedback timing on learning and brain function in individuals with moderate-to-severe traumatic brain injury (TBI), with and without depression.
- Trial name
- NCT05009511
- Testing
- Learning through feedback
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
ADHD, Dyslexia
A Strength-Based Intervention to Improve Job Interview Skills in Neurodiverse Young Adults
the investigators are looking to evaluate the effectiveness of a strength-based program in improving job interview skills in neurodiverse young adults.
- Conditions
- ADHD, Dyslexia, Learning Disabilities
- Trial name
- NCT06479850
- Testing
- KF-STRIDE®
- Volunteers
- 50 people
- Sponsor
- Kessler Foundation
Autism Spectrum Disorder
A Strength-Based Intervention to Improve Job Interview Skills in Young Adults in a Community Setting
The investigators are looking to evaluate how effective a strength-based intervention may be in improving job interview skills in young adults.
- Trial name
- NCT06380569
- Testing
- KF-STRIDE®
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kessler Foundation
Spinal Cord Injuries, Cognitive Dysfunction
Early Intervention for Information Processing Speed Deficits in Acute SCI: A Pilot Study
This study seeks to conduct a pilot study to test whether a cognitive training program can improve processing speed abilities in individuals with acute traumatic spinal cord injury.
- Conditions
- Spinal Cord Injuries, Cognitive Dysfunction, Cognitive Impairment, Acute Spinal Cord Injury
- Trial name
- SCI-IQ (NCT06452264)
- Testing
- game-like computerized activities
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kessler Foundation
Spinal Cord Injuries, Cognitive Dysfunction
A Pilot RCT to Improve Cognitive Processing Speed in Acute SCI
This study seeks conduct a pilot study to test whether a cognitive training program can improve processing speed abilities in individuals with acute traumatic spinal cord injury.
- Conditions
- Spinal Cord Injuries, Cognitive Dysfunction, Cognitive Impairment, Acute Spinal Cord Injury
- Trial name
- SCI-IQ (NCT06238492)
- Testing
- game-like computerized activities
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Kessler Foundation
SCI - Spinal Cord Injury
The Efficacy of Upper Extremity Wearable Robotic Orthosis on Improving Upper Extremity Motor Function and Activities of Daily Living in Persons With Spinal Cord Injury
To evaluate the usefulness of an upper extremity (UE) assistive device, called (MyoPro) in improving upper extremity activities in people with incomplete spinal cord injury (iSCI)
- Trial name
- MyoMo in SCI (NCT04855812)
- Testing
- MyoMo, Myo-SB, Control
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury
Using Virtual Reality to Improve Job Reentry in Adults With TBI
The purpose of this research is to investigate the effectiveness of virtual reality (VR) to improve job reentry skills in individuals with TBI.
- Trial name
- NCT04820634
- Testing
- Virtual Reality Job Interview Training, Wonderworks
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kessler Foundation
Autism Spectrum Disorder
KF STRIDE to Improve Job Interview Skills
The goals of the current study are to evaluate the preliminary effectiveness and feasibility of Kessler Foundation-Strength Identification and Expression (KF-STRIDE) in an 8-week randomized controlled trial comparing the…
- Trial name
- NCT04820647
- Testing
- KF-STRIDE
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury
Improving New Learning and Memory in School Aged Children
The currently proposed study addresses a critical need in the clinical care of school-aged children with TBI through the modification of an existing, proven efficacious treatment protocol for learning and memory deficits in…
- Trial name
- NCT04741360
- Testing
- Modified Story Memory Technique
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis, Relapsing-Remitting
An Examination of Cognitive Fatigue Using Functional Neuroimaging
The purpose of this research study is to investigate the effectiveness of MS Disease modifying medications on cognitive fatigue in persons with relapsing remitting multiple sclerosis (RRMS).
- Trial name
- NCT04885894
- Testing
- Zeposia
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Autism Spectrum Disorder, Autism
Examining the Effects of a Job Entry Intervention
The current study will examine the efficacy of a virtual reality (VR) intervention as well as a newly developed Kessler Foundation STRength IDentification and Expression tool (VR-STRIDE) with adolescents diagnosed with autism…
- Conditions
- Autism Spectrum Disorder, Autism, ASD
- Trial name
- IMPRESSIVE (NCT04771338)
- Testing
- VR-JIT/KF-STRIDE
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Traumatic Brain Injury, Upper Extremity Dysfunction
TeleRehab to Restore Upper Limb Function in People With Chronic TBI
The study aims to inform the subsequent large-scale clinical trial focused on using telerehabilitation techniques and technologies to improve upper limb function and quality of life.
- Conditions
- Traumatic Brain Injury, Upper Extremity Dysfunction, Disability Physical
- Trial name
- NCT06184932
- Testing
- HAHE, Exergame
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury
Improving Anticipatory and Compensatory Postural Responses to Avoid Falls After TBI
The purpose of this study is to assess a balance training program to see if it can be helpful to avoid falls in people who have had traumatic brain injuries (TBIs).
- Trial name
- NCT05268484
- Testing
- Perturbation-based Training with visual cues using Neurocom
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Traumatic Brain Injury
Study to Improve Ambulation in Individuals With TBI Using Virtual Reality -Based Treadmill Training
The purpose of this research study is to test the effectiveness of virtual reality (VR) based treadmill training on walking ability.
- Trial name
- NCT05130658
- Testing
- Virtual reality treadmill training, Treadmill Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Frailty, Cancer
ReVital-CORE Program
Pilot feasibility study of the ReVital Chemotherapy Online Resiliency Evaluation (CORE) program. As part of standard of care, patients starting a new chemotherapy regimen are referred to complete a pre-chemotherapy cancer…
- Conditions
- Frailty, Cancer, Chemotherapy-Induced Change
- Trial name
- ReVital-CORE (NCT04852575)
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury
Assistive Soft Skills and Employment Training (ASSET) in TBI Injury
Pediatric traumatic brain injury (TBI) is often associated with difficulties in social functioning. Loss of social contacts and difficulties maintaining social connections is common after pediatric TBI, extending into adulthood.
- Trial name
- NCT05705817
- Testing
- Assistive Soft Skills and Employment Training (ASSET)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kessler Foundation