Clinical trials: sponsored by Kessler Foundation
Traumatic Brain Injury, Attention Impaired
Online Intervention for Traumatic Brain Injury Wellbeing
Traumatic brain injury (TBI) patients face notable impairments which lead to reduced performance and regulation of daily and overall functioning.
- Conditions
- Traumatic Brain Injury, Attention Impaired, Emotional Regulation
- Trial name
- NCT05115656
- Testing
- Online group 1, Online group 2
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury
Emotional Processing Intervention for Children With TBI
Investigating an emotional processing program, that is modified for use with children, is effective for children with a traumatic brain injury (TBI).
- Trial name
- NCT04826068
- Testing
- Emotional Processing
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Multiple Sclerosis
Meeting an Unmet Need in Multiple Sclerosis
The primary objectives of this study is to examine the efficacy of the Unified Protocol in decreasing depression and anxiety among individuals with MS and the secondary outcomes (e.g., improved well-being, QOL, coping, etc.) that…
- Trial name
- NCT05953519
- Testing
- Unified Protocol
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Kessler Foundation
Stroke
Targeted Noninvasive Brain Stimulation to Improve Hand Dexterity in Stroke Patients
This study will investigate the use of High-definition Transcranial Direct Current Stimulation (HD-tDCS) in the functional improvement of hand dexterity while performing music-assisted hand exercises.
- Trial name
- T-NIBS (NCT04058288)
- Testing
- High-definition Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury, Partner Caregiver
Comparison of Two Group Wellness Interventions in TBI Partner Caregivers
The purpose of this research study is to compare the effect of two different types of group wellness interventions for partner caregivers of individuals with traumatic brain injury (TBI).
- Trial name
- NCT04192227
- Testing
- EnHAncing BehavIors through wellness TreatmentS (HABITS)
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Kessler Foundation
Stroke, Spatial Neglect
Development of a Virtual Reality Spatial Retraining Therapy to Improve Neglect in Stroke Survivors
Participants in this study will help test and develop a virtual reality (VR) system that is being designed to help people with spatial neglect after stroke.
- Trial name
- VR-SRT (NCT04793516)
- Testing
- VR Therapy Game
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation
SCI - Spinal Cord Injury
Combining Wearable Robotic Orthosis With Visual and Haptic Feedback to Enhance the Recovery of Upper Extremity Motor Function and ADL in Persons With Acute SCI
This randomized clinical trial (RCT) is evaluating the usefulness of combining MyoMo robotic orthosis with visual and haptic feedback in ameliorating wrist/hand/UE movement capability, and increasing ADL and quality of life in…
- Trial name
- NCT05386537
- Testing
- MyoMo orthosis and VR games, MyoPro robot only, Games only
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kessler Foundation
Brain Injuries, Traumatic
Home-based Arm and Hand Exercise to Improve Upper Limb Function After Traumatic Brain Injury
The purpose of this study is to find out whether the Home-based Arm and Hand Exercise (HAHE) program improves functions of the upper limb that is affected after traumatic brain injury.
- Trial name
- NCT03401645
- Testing
- Wrist Alarm, Home-based Arm and Hand Exercise
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Kessler Foundation
Spinal Cord Injuries
Treating Cognitive Deficits in Traumatic Spinal Cord Injury (SCI)
The purpose of this research study is to investigate the effectiveness of a memory retraining program and a processing speed program in a spinal cord injured (SCI) population.
- Trial name
- NCT03985540
- Testing
- Behavorial; memory exercise, Behavioral: speed exercises
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury, Mild Cognitive Impairment
Speed of Processing Training to Improve Cognition in Traumatic Brain Injury and Mild Cognitive Impairment
The purpose of this research study is to investigate the effectiveness of a technique designed to improve processing speed (i.e. the amount of time it takes to process information) in a Traumatic Brain Injury (TBI) population.
- Trial name
- NCT02020564
- Testing
- Speed of Processing Training
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis
Comparison of Two Physical Activity Interventions in Individuals With Multiple Sclerosis
This study will examine the effectiveness of aquatic therapy on a range of MS-related symptoms such as cognition, mood, fatigue and quality of life (QOL).
- Trial name
- NCT02496416
- Testing
- Aquatic Exercise Program, Stretching Program
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis
Remote Exercise Effects on Cognitive Processing Speed in Multiple Sclerosis: A Pilot Trial
Cognitive processing speed (CPS) impairment is prevalent, impactful, and poorly-managed in multiple sclerosis (MS). Upwards of 67% of patients present with MS-related CPS impairment, which is associated with poor everyday life…
- Trial name
- REACT-MS (NCT05344040)
- Testing
- Remotely Delivered and Supported Aerobic Walking Exercise Training, Remotely Delivered and Supported Stretching and Toning Exercise Training
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury, Weakness, Muscle
Physical and Mental Practice for Bimanual Coordination Rehabilitation
Traumatic Brain Injury (TBI)patients often suffer from loss of muscle strength in the hand and foot, decrease in coordination and high muscle tone (spasticity).
- Conditions
- Traumatic Brain Injury, Weakness, Muscle, Coordination Impairment
- Trial name
- NCT03817086
- Testing
- Hand coordination and mental practice, Hand coordination and action observation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Kessler Foundation
Spinal Cord Injuries
Repetitive Transcranial Magnetic Stimulation to Promote Regeneration in Persons With SCI
This is a research study to evaluate the safety, efficacy and feasibility of high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) in patients with subacute spinal cord injury.
- Trial name
- rTMS (NCT05333770)
- Testing
- High-frequency repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kessler Foundation
Spinal Cord Injuries, Tendinopathy
Ultrasound-Guided Treatments for Shoulder Pain in Wheelchair Users With Spinal Cord Injury
Rotator cuff disease (i.e., rotator cuff tendinopathy or tear) is a common cause of shoulder pain in persons with chronic spinal cord injury (SCI).
- Conditions
- Spinal Cord Injuries, Tendinopathy, Rotator Cuff Tears, Shoulder Pain
- Trial name
- MFAT-SCI (NCT04136743)
- Testing
- Lipogems, Dexamethasone
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis
Reinventing Yourself With Multiple Sclerosis (MS)
Given the knowledge that detriments in QOL, well-being, and participation are common in MS and attributable in a large part to individual, person-specific factors (e.g., self-efficacy), efforts to develop interventions aimed at…
- Trial name
- NCT05195320
- Testing
- Reinvention with MS
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Kessler Foundation
Spinal Cord Injuries, Brain Injuries
Interventional Cooperative Agreement Program - Vocational Intervention Demonstration
For many people with spinal cord injury or brain injury, seeking employment after injury is an important goal. There are services available to help people with disabilities.
- Conditions
- Spinal Cord Injuries, Brain Injuries, Employment, Spinal Cord Diseases
- Trial name
- NCT05508802
- Testing
- State Counselor-Coordinated Services, Center Facilitator-Coordinated Services
- Volunteers
- 500 people
- Sponsor
- Kessler Foundation
Spinal Cord Injuries, Spinal Cord Diseases
Early Intervention to Promote Return to Work for People With Spinal Cord Injury
For many people with spinal cord injury, seeking employment after injury is an important goal. There are services available to help people with disabilities.
- Trial name
- NCT05506657
- Testing
- State Counselor-Coordinated Services, Center Facilitator-Coordinated Services
- Volunteers
- 162 people
- Sponsor
- Kessler Foundation
Spasticity
"Epidural Spinal Cord Stimulation: Addressing Spasticity and Motor Function"
This study aims to expand the knowledge and capacity for neuromodulation to improve the debilitating effects of severe spasticity (spasms, tonic muscle activity and/or clonus) in persons with spinal cord injury (SCI).
- Trial name
- NCT05422716
- Testing
- Epidural implant stimulation device
- Volunteers
- 20 people
- Sponsor
- Kessler Foundation
Osteoarthritis, Knee, Knee Pain Chronic
Phenol Neurolysis of Genicular Nerves for Osteoarthritic Knee Pain
As the aging and obese populations continue to increase, there is a rapidly growing number of people at risk for knee osteoarthritis. Treatment typically starts conservatively with analgesics, physical therapy, and bracing.
- Trial name
- NCT04989660
- Testing
- 6% aqueous phenol, Isotonic saline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation