Clinical trials: sponsored by Kessler Foundation
Brain Injury
Biofeedback Gait Retraining for Stiff Knee Gait Correction
The research team has developed a visual kinematic biofeedback system which is designed to help children with hemiplegic cerebral palsy (CP) correct a pattern of reduced knee extension in terminal swing and early stance.
- Trial name
- NCT05105763
- Testing
- Sequential switched feedback training on the knee and the hip (Condition A), Feedback training on the knee alone (Condition B)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury With Loss of Consciousness
Strategy + RehaCom for Memory Rehabilitation in Traumatic Brain Injury (TBI)
The purpose of this research study is to evaluate the effectiveness of "RehaCom," a computerized treatment for memory deficits, in a 16-session, interactive course.
- Trial name
- REHACOM-NJHF (NCT04239456)
- Testing
- RehaCom (software)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis
Applying Speed of Processing Training to Individuals With Multiple Sclerosis
This pilot study will document the efficacy of a behavioral intervention for Processing Speed (PS) in Multiple Sclerosis (MS), Speed of Processing Training (SPT), which has been successful used in the aging population in several…
- Trial name
- SPTMS (NCT01838824)
- Testing
- Speed of Processing Training
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Kessler Foundation
Spinal Cord Injuries, Incomplete Spinal Cord Injury
A Novel System for Quasi Real-Time Tracking of Neuromuscular Responses During NMES
Neuromuscular electrical stimulation (NMES) remains as one of the effective rehabilitation modalities for addressing recovery of neuromuscular function after a spinal cord injury (SCI).
- Trial name
- NCT05243576
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Hemiplegic Cerebral Palsy
Dual Joint Visual Feedback Gait Retraining in Pediatric Hemiplegic Cerebral Palsy
This study aims to assess the feasibility of a visual feedback system designed to augment treadmill-based gait training for children with gait disturbances related to hemiplegic cerebral palsy.
- Trial name
- NCT05011201
- Testing
- Dual Joint Visual Feedback without Scoring, Dual Joint Visual Feedback with Scoring
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Kessler Foundation
TBI (Traumatic Brain Injury) or MS (Multiple Sclerosis)
Improving Learning in Hispanics With TBI or MS
The goal of this study is to establish that a memory retraining protocol, originally developed for English-speakers, and translated into Spanish, is effective.
- Trial name
- NCT03453125
- Testing
- Spanish modified Story Memory Technique (mSMT)
- Where
- 2 sites in United States, Spain
- Volunteers
- 40 people
- Sponsor
- Kessler Foundation
Spinal Cord Injuries, Spinal Cord Diseases
Comparison of Two Web-Based Education/Support Programs for Partner Caregivers of People With Spinal Cord Injury
The purpose of this research study is to compare the effect of two different types of education and support programs for partner caregivers of people with spinal cord injury (SCI).
- Trial name
- NCT04827095
- Testing
- Web-Based Support and Education Program 1, Web-Based Support and Education Program 2
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Neuropathic Pain, Spinal Cord Injury
Brain Activity in People With Chronic Neuropathic Pain and Spinal Cord Injury
The purpose of this research study is to learn more about how patterns of brain activity change during different thinking tasks and how these changes relate to the intensity and unpleasantness of the neuropathic pain that people…
- Trial name
- NCT04386174
- Testing
- Neurofeedback
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kessler Foundation
TBI (Traumatic Brain Injury)
The Development of a Virtual Reality Program to Improve Attention in Individuals With TBI
The purpose of this research is to investigate the effectiveness of a technique designed to improve divided attention and set-shifting impairments in persons with a traumatic brain injury (TBI).
- Trial name
- NCT03605017
- Testing
- Virtual Reality Executive Function Training (VREFT)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Kessler Foundation
Motor Learning in TBI
Sleep Study Among Inpatients With TBI in an Acute Rehabilitation Hospital
The purpose of this research study is to better understand how a daytime nap after training on a motor skill after brain injury improves performance compared with the same amount of time after training spent awake and resting.
- Trial name
- NCT02236676
- Testing
- Nap after rehearsal trials
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Kessler Foundation
Left-Hemisphere Stroke
Brain Markers Predicting Reading Recovery After Stroke
For millions of stroke survivors acquired reading deficits represent a significant handicap preventing them from returning to work or continuing their education.
- Trial name
- NCT03845686
- Testing
- Perfusion functional Magnetic Resonance Imaging (perfusion fMRI)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis, Emotional Disturbances
A Social Emotion Regulation Intervention in MS
The current project will examine effectiveness of an intervention based on the concept of the social regulation of emotion. The intervention is designed to improve well-being in individuals with MS by leveraging participants'…
- Trial name
- NCT03951974
- Testing
- Social Emotion Regulation Strategy Development, Control
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Kessler Foundation
Stroke, Delirium
Spatial Neglect and Delirium After Stroke
The goal of this study is to understand what brain mechanisms become disrupted when stroke survivors experience delirium. Delirium is an acute reduction in attention and cognition, associated with poor recovery, longer…
- Conditions
- Stroke, Delirium, Spatial Neglect
- Trial name
- NCT03349411
- Testing
- Confusion Assessment Method, Behavioral Inattention Test, Magnetic Resonance Imaging
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury
Investigating How Sleep After Training Can Affect the Learning of a Motor Skill in Individuals With Brain Injury
Studies have shown that a period of sleep, even in the form of a daytime nap, after a period of training on a motor learning task can boost subsequent performance beyond that observed after an equal amount of time spent awake and…
- Trial name
- NCT04810442
- Testing
- Nap
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Kessler Foundation
Stroke, Acute
Robotic Exoskeleton Gait Training During Acute Stroke Rehabilitation
The objective of this RCT is to explore the clinical, functional and neurophysiological effectiveness of RE-assisted (Robotic Exoskeleton) early intervention gait therapy in stroke patients during inpatient and outpatient stroke…
- Trial name
- RERC (NCT04775693)
- Testing
- RE (Robotic Exoskeleton), SOC (standard of care)
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury
Treating Emotional Processing Impairments in Individuals With TBI
The current project will examine the impact of an emotional processing intervention on emotional processing abilities in a sample of 50 persons with moderate to severe TBI. Outcome will be assessed across 3 domains.
- Trial name
- NCT03373331
- Testing
- Emotional Processing Training
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Kessler Foundation
Spatial Neglect, Deficits in Attention Motor Control and Perception
Prism Adaptation Therapy for Spatial Neglect
The purpose of this research study with a randomized controlled design is to examine the effects of prism adaptation treatment on two visual-spatial recovery components.
- Trial name
- NCT00989430
- Testing
- Prism Adaptation Treatment
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Kessler Foundation
Stroke
Spatial Neglect and Bias in Near and Far Space
The purpose of this research study is to learn how people distribute their visual attention when looking at objects nearby versus far away, and why vision may become distracted at near versus far distances.
- Trial name
- NCT00350012
- Where
- United States
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Stroke, Stroke, Acute
Improving Medication Self-Administration and Health After Brain Injury
The purpose of this research study is to assess medication self-administration (MSA) and the impact of three different interventions on improving medication adherence.
- Conditions
- Stroke, Stroke, Acute, Cognitive Impairment, Brain Injuries, Traumatic
- Trial name
- NCT03885674
- Testing
- Video Call Reminder Condition, Automated Text Message Reminder Condition
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Kessler Foundation
Aphasia, Stroke
Levetiracetam (Keppra) to Improve Chronic Aphasia in Post-stroke Patients.
The study investigates the possibility that levetiracetam may improve the symptoms of chronic post-stroke aphasia.
- Trial name
- NCT00227461
- Testing
- Wait first, then levetiracetam, Levetiracetam first, then wait
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Kessler Foundation