Clinical trials: sponsored by Kessler Foundation
Spinal Cord Injury
TRT in Combination With Electrical Stimulation and Standing: Effect on Muscle and Bone in Spinal Cord Injured Males
The aim of this study is to understand what happens to muscle and bone in spinal cord injured males after four months of training using stand training, with body weight support (BWS), with testosterone replacement therapy (TRT)…
- Trial name
- NCT02317640
- Testing
- Testosterone Gel applied by a pump, Stand Training, Electrical Stimulation
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Kessler Foundation
Spatial Neglect, Aphasia
An Assessment of the Prevalence of Spatial Neglect in Stroke Survivors With Aphasia
The purpose of this study is to determine if stroke survivors with aphasia have spatial neglect (Phase 1). If they are determined to have the condition Phase 2 will be offered: which is prism adaptation treatment.
- Conditions
- Spatial Neglect, Aphasia, Stroke
- Trial name
- NCT02068664
- Testing
- prism adaptation treatment
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kessler Foundation
Stroke
Feasibility of Using Prism Adaptation to Treat Spatial Neglect and Motor Function in Stroke
This research project is a study designed to address both motor and cognitive changes after stroke. Treatment for SN is elusive however there is support for prism adaptation treatment (PAT).
- Trial name
- NCT02419222
- Testing
- Prism Adaptation
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Kessler Foundation
Stroke, Foot Drop
Effect of FES Interventions on Gait Dynamics in Stroke Population
Our proposal quantitatively analyzes gait dynamics of hemiplegic individuals in response to the Function Electrical Stimulation (FES) intervention and identifies the responders to the intervention.
- Trial name
- NCT01952613
- Testing
- FES
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis
Physical Activity in Multiple Sclerosis (MS): A Novel Approach to Study Outcomes
Physical activity and exercise interventions in multiple sclerosis (MS) have received great attention most recently and there exists several randomized clinical trials (RCTs) addressing the outcomes associated with such…
- Trial name
- PHYSACTINMS (NCT02297932)
- Testing
- Strength training, Stretching
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury
Cogmed for Working Memory After TBI
This study will examine a cognitive rehabilitation protocol targeted at working memory deficits for adults and children with Traumatic Brain Injury (TBI).
- Trial name
- Cogmed (NCT02305212)
- Testing
- Cogmed
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis
Stylistic Memory Enhancement
Impairments in higher level cognitive processing, such as new learning and memory, are common in Multiple Sclerosis (MS) and negatively impact multiple aspects of everyday life, including occupational and social functioning.
- Trial name
- SME (NCT03206034)
- Testing
- Stylistic Memory Enhancement
- Volunteers
- 20 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis, Progressive, Cognition - Other
Treating New Learning and Memory Deficits in Progressive Multiple Sclerosis (MS)
This study is a double-blind placebo-controlled randomized clinical trial (RCT) to provide Class I evidence in support of or in refute of the efficacy of the modified Story Memory Technique (mSMT) in persons with progressive MS…
- Conditions
- Multiple Sclerosis, Progressive, Cognition - Other, Memory Impairment
- Trial name
- NCT02301247
- Testing
- Memory retraining exercises
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Kessler Foundation
Disuse Osteoporosis, Atrophy, Disuse
Activity Dependent Rehabilitation Model to Improve Bone and Muscle Outcomes
For many after spinal cord injury (SCI) there is immobilization, muscle atrophy, bone loss, fracture risk during transferring (or falls), and the risk of secondary complications, and increase in attendance care and cost.
- Conditions
- Disuse Osteoporosis, Atrophy, Disuse, Nervous System, Structural; Marker
- Trial name
- NCT02309983
- Testing
- Electrical Stimulation, Stand Retraining with Body Weight Support (BWS)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Kessler Foundation
Spinal Cord Injury
Non-Ambulatory SCI Walk Using a Robotic Exoskeleton: Effect on Bone and Muscle
The purpose of this research study is to evaluate an exoskeleton device and mobility skills in the device.
- Trial name
- NCT02324322
- Testing
- Exoskeleton Training, Muscle Biopsies, MRI
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury
Improving Balance in TBI Using Virtual Reality
This research study evaluates the effectiveness of a low-cost Virtual Reality-based (VR) training system in providing a customized balance treatment in a skilled clinical setting.
- Trial name
- NCT02298231
- Testing
- Standard of Care Balance Intervention, Mystic Isle Balance Intervention, Mystic Isle Balance Intervention with Dual Task
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis
Consolidation & Interference in Multiple Sclerosis
The purpose of this research study is to investigate whether minimizing interference improves memory in multiple sclerosis.
- Trial name
- NCT02081508
- Testing
- Interference onset
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Stroke, Drop Foot
Pairing Functional Electrical Stimulation (FES) and Volitional Effort Training Promotes Neuroplasticity and Motor Gain
The goal of the study is to explore the effect of combined training involving functional electrical stimulation (FES) of the ankle dorsal flexor with simultaneous maximal-effort voluntary contraction of the same muscle to correct…
- Trial name
- NCT02797886
- Testing
- FES + VOL, FES, VOL
- Volunteers
- 45 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury
Applying Speed of Processing Training to Individuals With Traumatic Brain Injury
This pilot study will document the efficacy of a behavioral intervention for Processing Speed (PS) in Traumatic Brain Injury (TBI), Speed of Processing Training (SPT), which has been successful used in the aging population in…
- Trial name
- SPTTBI (NCT01838811)
- Testing
- Speed of Process Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury
Improving New Learning and Memory in Traumatic Brain Injury
The current study is a double-blind, placebo-control randomized clinical trial examining the efficacy of memory retraining in Traumatic Brain Injury (TBI).
- Trial name
- NCT01207375
- Testing
- memory retraining exercises
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Kessler Foundation
Spinal Cord Injury, Spasticity
The Effect of Whole Body Vibration on Spasticity in Persons With Spinal Cord Injury
Extended periods of tilt table standing have been observed to improve spasticity in individuals with spinal cord injury (SCI). The purpose of this study is to determine the effect of three sessions of whole body vibration while…
- Trial name
- NCT02127606
- Testing
- Vibration with tilt-table standing
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Kessler Foundation
Insomnia, Brain Injury
Effect of Rozerem on Sleep Among People With Traumatic Brain Injury
This pilot study proposes to examine the effect of Rozerem on sleep/wake patterns among individuals with Traumatic Brain Injury (TBI) experiencing sleep disturbance, using both objective and subjective measures.
- Trial name
- NCT01207050
- Testing
- Ramelteon
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis
Testing the Efficacy of Self-Generation Treatment Protocol
Past research has shown that items self-generated by an individual, such as words or concepts, are remembered better than items that are simply read or heard.
- Trial name
- NCT02032589
- Testing
- Self-generation treatment
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury
Aerobic Exercise to Improve Memory in TBI
Aerobic exercise holds a multitude of health benefits. Studies in mice have shown that aerobic exercise improves memory, and increases the volume of the hippocampus, the brain's primary memory center.
- Trial name
- NCT01952704
- Testing
- Aerobic exercise
- Volunteers
- 24 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis
Modafinil in Multiple Sclerosis
Deficits in new learning and memory in MS are a major complaint of patients, and have been noted to be a significant contributor to disability by numerous researchers.
- Trial name
- NCT00142402
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kessler Foundation