Clinical trials: sponsored by Laval University
Respiratory Failure
Effects of Treatment With High Flow Nasal Cannulas on Respiratory Pattern and Work of Breathing Among Healthy Subjects
This study evaluates the work of breathing among healthy subjects under various conditions of treatment with high flow nasal cannulas. Ten subjects will be included.
- Trial name
- HDWOBSS (NCT02495675)
- Testing
- High flow nasal cannulas, Conventional flow via nasal prongs
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Laval University
Respiratory Failure
Effects of Treatment With High Flow Nasal Cannulas on Respiratory Pattern and Work of Breathing Among Patients.
This study evaluates the work of breathing among patients under various conditions of treatment with high flow nasal cannulas. Sixteen spontaneously breathing patients with respiratory failure (hypercapnic or hypoxemic) will be…
- Trial name
- HDWOBPT (NCT02494154)
- Testing
- Airvo 2; Ficher and Paykel HealthCare, Oxygen delivery via conventional nasal mask
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Laval University
Stable Angina, Unstable Angina Pectoris
Opsens Optowire for Fractional Flow Reserve - The O2 Pilot Study
The purpose of this study is to assess the usability and safety of the Opsens OptoWire and Optomonitor in measuring fractional flow reserve (FFR) in patients with coronary artery disease who are undergoing a coronary angiogram.
- Conditions
- Stable Angina, Unstable Angina Pectoris, Chest Pain, Ischemia
- Trial name
- O2 (NCT02144090)
- Testing
- Fractional flow reserve measurement
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Laval University
Chronic Kidney Disease
Study of Atorvastatin Dose Dependent Reduction of Proteinuria
Randomized controlled double blind study of parallel groups to evaluate the comparative effects of low-dose of atorvastatin on proteinuria in patients with stage 3 or 4 chronic kidney disease.
- Trial name
- SARP (NCT00768638)
- Testing
- Atorvastatin
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Laval University
Preeclampsia
Consumption of Chocolate in Pregnant Women.
The purpose of this study is to investigate the acute and chronic effect of consumption of flavanol-rich chocolate on endothelium function in pregnant women at high risk for preeclampsia.
- Trial name
- CHOCENTA (NCT01431443)
- Testing
- Flavanol-rich chocolate
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Laval University
Lung Cancer
Intervention to Improve Continuity of Care in Lung Cancer Patients
Many authors have recognized the need to overcome the different barriers to continuity of cancer care, such as inadequate communication between specialists and family physicians (FP), insufficient information provided for the…
- Trial name
- NCT01389739
- Testing
- Multi-faceted intervention to improve continuity of care
- Where
- Canada
- Volunteers
- 206 people
- Sponsor
- Laval University
Dementia
Palliative and End-of-life Care in Advanced Dementia: Evaluation of a Program of Organization of Care in Long-term Care
Rationale: In Canada, as in most industrialized countries, Alzheimer's disease and other related dementia are increasingly prevalent in older people.
- Trial name
- NCT01441726
- Where
- Canada
- Volunteers
- 175 people
- Sponsor
- Laval University
Infertility
Control Ovarian Stimulation Timing Test
IVF (in vitro fertilization) cycles fails more often than they succeed. Surprisingly very little effort is invested in defining the reasons for failure and possibly finding ways to improve the success on the next cycle.
- Trial name
- COST2 (NCT02397135)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Laval University
Shoulder Impingement Syndrome
Effects of a Movement Training for Subacromial Pain Syndrome
Objectives: Evaluate the effects of a rehabilitation program based on movement training on symptoms, functional limitations and acromiohumeral distance (AHD) in individuals with SPS.
- Trial name
- MTforSPS (NCT02395770)
- Testing
- Rehabilitation program
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- Laval University
Chronic Obstructive Pulmonary Disease, Metabolic Syndrome
Impact of Roflumilast on Visceral Adiposity and Metabolic Profile in Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine whether roflumilast can improve metabolic profile and reduce visceral adiposity in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- RAMBO (NCT01701934)
- Testing
- Roflumilast
- Where
- 5 sites in Canada
- Volunteers
- 14 people
- Sponsor
- Laval University
Familial Hypercholesterolemia
Relationships Between Plasma PCSK9 Levels, LDL-cholesterol Concentrations and Lipoprotein (a) Levels in Familial Hypercholesterolemia
Familial hypercholesterolemia (FH) is an autosomal codominant single gene disorder caused by mutations in the LDL receptor gene (LDLR) that disrupt the normal clearance of LDL particles from the plasma.
- Trial name
- NCT02225340
- Where
- Canada
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Laval University
COPD, Exercise
Evaluation of Automatic Oxygen Flow Titration During Walking in Patients With COPD
The aim of the current study was to evaluate a new system (FreeO2) that automatically titrates oxygen flow to maintain stable SpO2, in patients with moderate or severe chronic obstructive pulmonary disease during exercise.
- Conditions
- COPD, Exercise, Endurance Shuttle Walking Test (Exercise at 85% of Maximal Shuttle Walking Test)
- Trial name
- FreeO2rehab (NCT02150434)
- Testing
- Automated oxygen titration, Compressed air, Oxygen constant flow
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Laval University
Microalbuminuria, Gastrectomy
Resolution of Microalbuminuria and Dysmetabolism Following Bariatric Surgery: Prospective Study
Favorable effects of bariatric surgery have been demonstrated in particular regarding increased insulin sensitivity, decreased blood pressure, improved blood lipids and decreased cardiovascular risk.
- Conditions
- Microalbuminuria, Gastrectomy, Biliopancreatic Diversion With Duodenal Switch
- Trial name
- NCT02068833
- Testing
- Gastrectomy, BPD-DS
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Laval University
Biliopancreatic Diversion With Duodenal Switch, Gastrectomy
Physiological Impact of Each Component of the Biliopancreatic Diversion With Duodenal Switch and Sleeve Gastrectomy
Bariatric surgery procedures promote weight loss by limiting the amount of food consumed through reduction of the size of the stomach and by decreasing absorption of nutrients through reorganizing or bypassing portions of the…
- Trial name
- NCT02069223
- Testing
- Gastrectomy, BPD-DS
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Laval University
Chronic Kidney Disease
Acute Effects of Cinacalcet on Arterial Stiffness and Ventricular Function in Hemodialysis Patients
The primary objective is to determine whether reduction of serum calcium concentration by cinacalcet leads to reduction of mean blood pressure adjusted c-fPWV.
- Trial name
- ECIRA (NCT01250405)
- Testing
- Cinacalcet
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Laval University
Cardiovascular Disease
Impact of Dairy Consumption on Inflammation: a Clinical Study (PLI)
Inflammation and endothelial dysfunction are being increasingly recognized as key etiological factors in the development of atherosclerosis and subsequent cardiovascular disease (CVD).
- Trial name
- PLI (NCT01444326)
- Testing
- Dairy
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Laval University
Sub-clinical Inflammation
The Effect of Wobenzym PS on Inflammation
The general objective of this project is to examine the impact of Wobenzym PS supplementation on blood markers of inflammation and inflammation gene expression in volunteers with sub-clinical inflammation.
- Trial name
- WO (NCT01848808)
- Testing
- Wobenzym PS
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Laval University
Video-assisted Thoracoscopic Surgery, Lung Isolation Device
Lung Collapse With Bronchial Blocker
Lung isolation is frequently used during thoracic surgery. Two techniques are principally used: the double lumen tube (DLT) and the bronchial blocker (BB).
- Conditions
- Video-assisted Thoracoscopic Surgery, Lung Isolation Device, One-lung Ventilation, Double Lumen Endotracheal Tube
- Trial name
- NCT01615263
- Testing
- Lung isolation device
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Laval University
Knee Osteoarthritis
Effects of a New Knee Brace for Treatment of the Knee Osteoarthritis
The purpose of this study is to evaluate the immediate effects of a knee brace with a new mechanism on the pain and medial knee loading during gait among medial knee osteoarthritis patients.
- Trial name
- NCT01866176
- Testing
- Stabilizing Knee Brace, Valgus Knee Brace, New Knee Brace
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Laval University
Knee Osteoarthritis
Daily Activity After Corticosteroids Injection Among Knee Osteoarthritis Patients
The objective of this study was to objectively measure daily physical activity and spatiotemporal gait pattern, as well as improvements in self reported symptoms and quality of life, before and six weeks after an intra-articular…
- Trial name
- NCT02049879
- Testing
- Corticosteroids injection
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Laval University