Clinical trials: sponsored by Laval University
Chronic Obstructive Pulmonary Disease
Signaling Pathway Activation After Exercise in Patients With Chronic Obstructive Pulmonary Disease
Muscle weakness and atrophy are important consequences of chronic obstructive pulmonary disease (COPD). Although resistance exercises increase strength and muscle mass in patients with COPD, the response to training appears to be…
- Trial name
- SIM (NCT01561625)
- Testing
- exercise
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Laval University
Other Eating Disorders
Awakening to the Taste of Food Among Restrained Women
Energy-restricted diets often require dieting rules, which forced the dieter to eat according to cognitive norms, which increase his vulnerability to external food cues.
- Trial name
- Flaveur (NCT01535846)
- Testing
- Conscious food tasting intervention
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laval University
Obstructive Sleep Apnea, Obesity
Sibutramine Versus Continuous Positive Airway Pressure (CPAP)in Obstructive Sleep Apnea (OSA) Patients
The primary objective of this study is to observe if Sibutramine is effective in improving the symptoms and signs of sleep apnea in obese patients.
- Conditions
- Obstructive Sleep Apnea, Obesity, Hypertension
- Trial name
- NCT00729963
- Testing
- Sibutramine, CPAP
- Volunteers
- 45 people
- Sponsor
- Laval University
Metabolic Syndrome X
Study of the Relationships Between Apolipoprotein B-48 Kinetics and Expression of Genes That Regulate Intestinal Lipid Metabolism in Men With the Metabolic Syndrome (SMB48)
Several lines of evidence indicate that a significant proportion of cardiovascular disease (CVD) events are attributable to the presence of a cluster of metabolic abnormalities and perturbations, defined as the metabolic…
- Trial name
- NCT01829945
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Laval University
Metabolic Syndrome X
Effects of Medium-Chain Triglycerides on Chylomicron Secretion and Expression of Genes That Regulate Intestinal Lipid Metabolism in Men With Dyslipidemia Associated With the Metabolic Syndrome
Several lines of evidence indicate that a significant proportion of cardiovascular disease (CVD) events are attributable to the presence of a cluster of metabolic abnormalities and perturbations, defined as the metabolic…
- Trial name
- MCT (NCT01806142)
- Testing
- Medium-chain triglycerides, Corn oil
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Laval University
Gene Expression
Impact of a Short-Term High Fat or Low Fat Diet on Intestinal Genes Expression Involved in the Cholesterol and Fatty Acid Metabolism
Dietary fat has been shown to modulate cholesterol and fatty acids homeostasis and several lines of evidence suggest that this effect is associated with changes in the regulation of different genes at the intestine level involved…
- Trial name
- DGENES (NCT01806441)
- Testing
- 3-days high fat diet, 3-days low fat diet
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Laval University
Cardiovascular Disease
Ruminant Trans Fats and the Risk of Cardiovascular Disease in Women
While the deleterious effects of trans fat from industrial sources (iTFA) on cardiovascular health are well established, the impact of TFA from ruminants (rTFA) on cardiovascular risk factors has not been as well characterized.
- Trial name
- TRANSW (NCT00930137)
- Testing
- isocaloric for week diet
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Laval University
Cardiovascular Disease
Mediterranean Diet and the Metabolic Syndrome
While there is now undisputable evidence relating elevated plasma low-density lipoprotein (LDL) cholesterol levels to an increased risk of coronary heart disease (CHD), it is being increasingly recognized that a significant…
- Trial name
- MedDiet (NCT00988650)
- Testing
- isocaloric diet, free living conditions
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Laval University
Type 2 Diabetes
Effects of N-3 Polyunsaturated Fatty Acids On Chylomicron Secretion And Expression Of Genes That Regulate Intestinal Lipid Metabolism In Men With Type 2 Diabetes
The overaccumulation of apoB-48-containing lipoproteins of intestinal origin seen in patients with type 2 diabetes are now thought to be attributable to elevated intestinal production and reduced clearance.
- Trial name
- DBB48 (NCT01449773)
- Testing
- n-3 PUFAs
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Laval University
Cardiovascular Disease
Impact of Buttermilk on Cholesterol Concentration and Homeostasis
The role of low-density lipoprotein cholesterol (LDL-C) in the pathogenesis of cardiovascular disease (CVD) and the clinical benefit of lowering LDL-C in high-risk patients have both been well established.
- Trial name
- BMILK (NCT01248026)
- Testing
- Buttermilk
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Laval University
Obesity
Effect of a Drinkable Yogurt Enriched in Proteins and Fibers on Satiety
Worldwide, obesity rate has increased so much in the latest years, that we call it obesity epidemic. Overweight could result of an unbalanced energetic balance for years.
- Trial name
- JIVAGO (NCT01304004)
- Testing
- Satiety
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Laval University
Asthma, Chronic Obstructive Pulmonary Disease
Asthma & COPD Guideline Implementation
This is a report of a protocol developed to improve asthma and COPD care in a primary care setting. The study was approved by an Ethics Committee and support by the Canadian Thoracic Society through an unrestrictive grant from…
- Trial name
- NCT01766544
- Testing
- Standard Practice Group (SPG), TISG
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- Laval University
Diabetes Mellitus, Postprandial Lipemia
Effects of Sitagliptin on Postprandial Lipemia in Men With Type 2 Diabetes
Sitagliptin is a potent and selective inhibitor of dipeptidyl peptidase IV (DPP-4), and has been shown to reduce fasting and postprandial glucose levels in patients with type 2 diabetes mainly through incretin hormone-mediated…
- Trial name
- NCT00660075
- Testing
- Sitagliptin
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Laval University
Parkinson's Disease
The Effect of Methylphenidate on Non-motor Symptoms and Postural Control in Parkinson's Disease.
This project aims to determine if methylphenidate can improve deficits in attention and symptoms of orthostatic hypotension, two common non-motor symptoms, in patients with Parkinson's Disease.
- Trial name
- NCT01244269
- Testing
- Methylphenidate
- Where
- 2 sites in Canada
- Volunteers
- 6 people
- Sponsor
- Laval University
Chronic Obstructive Pulmonary Disease (COPD)
Electrostimulation, Skeletal Muscle Function, and Exercise Capacity in Chronic Obstructive Pulmonary Disease (COPD)
This study was designed to test the following hypothesis: The benefit of electrostimulation training will be greater than sham stimulation training in term of muscle strength and mass (muscle hypertrophy), exercise tolerance…
- Trial name
- ESTIM (NCT00874965)
- Testing
- Electrostimulation
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Laval University
Pulmonary Arterial Hypertension
Responsiveness of Exercise Tests in Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is characterized by the progressive increase in pulmonary vascular resistance leading to shortness of breath and exercise intolerance.
- Trial name
- RESPONS (NCT01391104)
- Testing
- Sildenafil, Sugar Pill
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Laval University
Parkinson's Disease
The Effect of Exercise Training on Gait and Quality of Life in Parkinson's Disease
The project aims to evaluate the effects of 24 weeks of treadmill training (TT), with and without a strengthening component, on functional mobility, gait and quality of life in patients with Parkinson's disease (PD).
- Trial name
- NCT01701128
- Testing
- Walking on treadmill, Control group
- Where
- 2 sites in Canada
- Volunteers
- 35 people
- Sponsor
- Laval University
Hypertension Pregnancy-induced
Chocolate Consumption in Healthy Pregnant Women Trial
The purpose of this study is to to test the feasibility of design methods and procedures for later use on a larger scale and to examine the acute and chronic effect of consumption of flavanol-rich chocolate on endothelium…
- Trial name
- NCT01659060
- Testing
- Flavanol-rich dark chocolate
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Laval University
Obesity, Osteoporosis
Milk Supplementation and Energy Balance.
The aim of the project is to determine if milk supplementation during a caloric restriction program facilitates the lost of weight, improves the appetite control and attenuates the decrease of bone mineral content in low-calcium…
- Trial name
- NCT00729170
- Testing
- Supplementation of milk (35% more calcium)
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Laval University
Endothelial Function
Impact of Spices and Herbs on Endothelial Function
The general objective of the study is to investigate the effects of the daily consumption of spices and herbs for four (4) consecutive weeks in endothelial function and cardiovascular risk factors of men and postmenopausal women.
- Trial name
- NCT01085019
- Testing
- Cinnamon, Oregano, Ginger
- Where
- 2 sites in Canada
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Laval University