Clinical trials: sponsored by Laval University
Asthma, Bronchial Hyperreactivity
Early Antiinflammatory Treatment of Asthma
The inflammatory process that leads to the development of asthma may be present before the onset of asthma symptoms and cause a certain degree of airway hyperresponsiveness.
- Trial name
- EATA (NCT00567463)
- Testing
- Fluticasone
- Where
- Canada
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Laval University
Cardiovascular Disease
Study of the Impact of Trans Fatty Acids From Dairy Products on Cardiovascular Risk Factors
The majority of trans fatty acids consumed by the general population is derived from products that have been formulated using significant amount of hydrogenated vegetable oil (the so-called industrial trans fat).
- Trial name
- TRANS (NCT01163175)
- Testing
- Ruminant trans fats
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Laval University
Chronic Obstructive Pulmonary Disease
Sensitivity of New Exercise Tests in Chronic Obstructive Pulmonary Disease (COPD)
This study was designed to test the following hypothesis: The 3-min constant rate step test and the 3-min constant rate shuttle walk test will be sensitive to detect improvement in exertional dyspnea following acute…
- Trial name
- NCT00807534
- Testing
- ipratropium bromide, constant rate step test, constant rate shuttle walk test
- Where
- 2 sites in Canada
- Volunteers
- 44 people
- Sponsor
- Laval University
Nasal Polyps, Asthma
Biopsies and Polyps
Background: Nasal polyps are found in about 5% of asthmatic patients.A close link exists between the upper and lower airways and the concept of the "United Airways" has emerged mainly from studies on allergic rhinitis and asthma.
- Trial name
- NCT00835445
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Laval University
COPD
Pulmonary Rehabilitation at Home Versus at the Gymnasium
Short term efficacy of pulmonary rehabilitation for improving functional capacity and quality of life of chronic obstructive respiratory disease (COPD) patient is well known.
- Trial name
- NCT00169897
- Testing
- Pulmonary rehabilitation (teaching and exercise)
- Where
- 10 sites in Canada
- Volunteers
- 252 people
- Sponsor
- Laval University
Insulin Resistance, Type 2 Diabetes
Fish Gelatin Supplement and Omega-3 Supplement in Obese or Overweight Subjects With Insulin Resistance
The present study was conducted to test whether a fish gelatin supplement combined with an omega-3 polyunsaturated fatty acid supplement can exert beneficial and sex-specific effects on insulin sensitivity, glucose tolerance…
- Trial name
- NCT01215903
- Testing
- Fish gelatin and omega-3 polyunsaturated fatty acid, Omega-3 polyunsaturated fatty acid
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Laval University
Cardiovascular Disease
Milk Consumption and the Metabolic Syndrome in Menopausal Women
Cardiovascular disease (CVD) represents the first cause of mortality in industrialized countries such as Canada and the United States.
- Trial name
- MILK (NCT01163773)
- Testing
- MILK
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Laval University
COPD
Tolerance to Electrostimulation in COPD Patients
The study was designed to test the following hypothesis Patients with high cardio-respiratory response to electrostimulation (ES), high perception of pain during ES and high ES-induced muscle fatigue, have low tolerance to ES…
- Trial name
- TOES (NCT00809120)
- Testing
- Neuromuscular Electrical stimulator (Cefar rehab 4 pro)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Laval University
Immune System
Dose Response Study of a Fermented Yogurt on the Immune System and Gut Health
The purpose of this study is to determine the dose-response effect of a yogurt containing a combination of bifidobacterium Lactis (BB-12) and Lactobacillus Acidophilus (LA-5) and green tea extract on markers of the immune system…
- Trial name
- PRO (NCT00730626)
- Testing
- Yogurt with 1X10E9 BB-12 and LA-5, Yogurt with 1X10E10 BB-12 and LA-5
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Laval University
Schizophrenia and Schizophrenia Spectrum Psychosis
Modafinil as an Adjunctive on Cognitive Functioning in Patients With Schizophrenia
Patients suffering from schizophrenia and schizophrenia spectrum psychosis frequently experience cognitive impairments. Such deficits may affect memory, attention and executive function processes.
- Trial name
- NCT00314639
- Testing
- modafinil
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
Asthma, Airway Hyperresponsiveness
Airway Dysfunction and Remodelling in Athletes Following Swimming Training in Chlorinated Pools
Swimmers show the highest prevalence of asthma among elite athletes, certainly due to chlorine exposure. The consequences of a chronic exposure to chlorine compounds by swimmers and the mechanisms of asthme in this population are…
- Trial name
- proto nage (NCT00686452)
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Laval University
Asthma
Effects of Budesonide & Budesonide/Formoterol on Smoking Asthmatic Subjects
A reduced response to inhaled corticosteroids (ICS) has been reported in smoking compared to non-smoking asthmatic patients. However, the comparative response to other currently prescribed medications such as combination therapy…
- Trial name
- D5890L00013 (NCT00691951)
- Testing
- budesonide and budesonide/formoterol
- Where
- 2 sites in Canada
- Sponsor
- Laval University
Diabetes, Coronary Artery Bypass Grafting
Vein-Coronary Atherosclerosis And Rosiglitazone After Bypass Surgery: The VICTORY Trial
HYPOTHESES Rosiglitazone in diabetic patients with previous coronary bypass surgery may prevent or slow the progression of atherosclerosis in SVGs and native coronary arteries.
- Trial name
- VICTORY (NCT00169832)
- Where
- 9 sites in Canada, Spain
- Volunteers
- 193 people
- Sponsor
- Laval University
Asthma, Allergic Rhinitis
CysLT1-r Expression Following Allergen Exposure in Asthma and Allergic Rhinitis
Cysteinyl leukotrienes (CysLTs) play an important role in asthma. CysLTs exert most of their bronchoconstrictive and pro-inflammatory effects through activation of the CysLT1-r.
- Trial name
- NCT00631254
- Testing
- Allergen challenge
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
Pleural Effusion, Coronary Artery Bypass
Pleural Effusion Following Cardiac Surgery: Prevalence, Risk Factors and Clinical Features
Pleural effusion is a common complication of cardiac surgery. The aim of this study was to determine the prevalence, characteristics and determinants of clinically significant pleural effusions, defined as those requiring…
- Trial name
- NCT00665015
- Where
- Canada
- Volunteers
- 2,892 people
- Sponsor
- Laval University
HIV Infections, Sexually Transmitted Diseases
Safety, Tolerance and Acceptability Trial of the Invisible Condom® in Healthy Women
The objectives of this clinical study are to evaluate the extended safety, tolerance and acceptability of a vaginal gel formulation when applied in 452 healthy women volunteers.
- Trial name
- NCT00136643
- Testing
- Invisible Condom®
- Where
- Cameroon
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Laval University
Chronic Obstructive Pulmonary Disease
Effects of Salmeterol on Walking Capacity in Patients With COPD
This study was designed to test the following hypothesis: The acute changes in exercise tolerance during the endurance shuttle walk will be greater with salmeterol compared to placebo in patients with chronic obstructive…
- Trial name
- NCT00525564
- Testing
- Salmeterol diskus inhalation powder
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Laval University
Coronary Artery Disease, Ischemia
EArly Discharge After Transradial Stenting of CoronarY Arteries: The EASY Study
HYPOTHESES Discharge on the same day after uncomplicated trans-radial coronary artery stenting is safe and effective. Hospitalized patients can be safely returned to the referring center the same day following trans-radial…
- Trial name
- NCT00169819
- Testing
- Abciximab
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- Laval University
Insulin Resistance, Type 2 Diabetes
Dietary Fish Protein in Subjects With Insulin Resistance
The objective of our research project is to determine the effects of fish protein, present in fish, on insulin sensitivity in insulin-resistant human individuals, and its mechanism of action on glucose metabolism.
- Trial name
- NCT00400036
- Testing
- Cod protein NCEP-diet
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Laval University
Obesity, Overweight
Effect of Calcium/Vitamin D Supplementation on Body Weight and Fat Loss.
The aim of this study was to assess the effect of calcium/vitamin D supplementation (Caltrate 600 +D®) on body weight loss during a weight-reducing program
- Trial name
- NCT00353054
- Testing
- Caltrate® 600 + D, Weight loss intervention
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Laval University