Clinical trials: sponsored by Linkoeping University
Hypertension,Essential
Licorice and Home Blood Pressure
Out-of-office blood pressure is more strongly associated with cardiovascular risk than office blood pressure. Licorice is known to raise blood pressure, but no previous studies have measured the effects on home blood pressure.
- Trial name
- NCT05661721
- Testing
- Sweet licorice, Salty licorice
- Where
- Sweden
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Liver Cirrhosis, Hepatocellular Carcinoma
Relevance of Sarcopenia in Advanced Liver Disease
Patients with established liver cirrhosis, or end-stage liver disease (ESLD), are at high risk of developing liver cancer (hepatic carcinoma; HCC), portal hypertension, and sarcopenia, all which lead to significant morbidity and…
- Conditions
- Liver Cirrhosis, Hepatocellular Carcinoma, Sarcopenia, Portal Hypertension
- Trial name
- ACCESS-ESLD (NCT05502198)
- Where
- 3 sites in Sweden
- Volunteers
- 150 people
- Sponsor
- Linkoeping University
Depression and Quality of Life
ICBT for Mental Health Problems Related to the Climate Crisis
The study seeks to investigate the effects of a guided internet-based cognitive behavioral therapy (ICBT) programme on adult mental health problems related to the climate crisis.
- Trial name
- NCT05169736
- Testing
- Cognitive Behavioural Therapy
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Linkoeping University
Pancreatitis
Osteopontin as a Biomarker in Pancreatitis
In the early phase of pancreatits, factors that can give information about the development of severety are still lacking. In this study patients will be included prospectively upon the diagnosis of pancreatits and clinical as…
- Trial name
- PtitStudien (NCT05882500)
- Testing
- No intervention, observation
- Where
- Sweden
- Volunteers
- 103 people
- Sponsor
- Linkoeping University
Idiopathic Normal Pressure Hydrocephalus
Gait Pattern and Experienced Global Change After Shunt Surgery in Idiopathic Normal Pressure Hydrocephalus
Part 1 Patients with idiopathic Normal Pressure Hydrocephalus (iNPH) have variable disabilities regarding gait, balance, cognition and continence.
- Trial name
- NCT04795089
- Testing
- Shunt surgery
- Where
- Sweden
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Non-cardiac Chest Pain, Cardiac Anxiety
Internet-delivered CBT for Patients With NCCP
Non-cardiac chest pain (NCCP) is common and has substantial impact on patients' psychological wellbeing, quality of life and healthcare use.
- Trial name
- IKSIT (NCT03336112)
- Testing
- Internet-delivered cognitive behavioral therapy (I-CBT), Information program
- Where
- Sweden
- Volunteers
- 109 people
- Sponsor
- Linkoeping University
Distal Humerus Fracture
Elbow Hemiarthroplasty Versus Total Elbow Arthroplasty for Irreparable Distal Humeral Fractures
Distal humeral fractures can be difficult to treat, in particular when the joint surface is affected (intra-articular fractures).
- Trial name
- NCT03596736
- Testing
- Elbow Hemiarthroplasty, Total Elbow Arthroplasty
- Where
- 3 sites in Sweden
- Volunteers
- 42 people
- Sponsor
- Linkoeping University
Portal Vein Embolization, Liver, Hypertrophy
Comparison of N-butyl-cyanoacrylate and Micro Parti-cles Effect in Inducing Liver Hypertrophy After PVE
The aim of this study is to compare hypertrophy of the FLR after PVE with microparticles to hypertrophy after PVE with cyanoacrylate in a material large enough to answer the study question.
- Trial name
- NCT05660759
- Testing
- Portal vein embolization
- Where
- Sweden
- Volunteers
- 265 people
- Sponsor
- Linkoeping University
Carotid Stenosis, Carotid Artery Plaque
CARotid Mri of Atherosclerosis
In the entire world most people die from cardiovascular disease. Death is primarily from myocardial infarction (MI) and stroke which are most often caused by rupture of atherosclerotic plaques. Patients with high-grade, i.e.
- Conditions
- Carotid Stenosis, Carotid Artery Plaque, Carotid Atherosclerosis
- Trial name
- CARMA (NCT04835571)
- Testing
- Optimization of cardiovascular risk management
- Volunteers
- 52 people
- Sponsor
- Linkoeping University
Ulcerative Colitis, Inflammatory Bowel Diseases
Colectomy Reconstruction for Ulcerative Colitis, Ileorectal Anastomosis vs Ileal Pouch-Anal Anastomosis in Ulcerative Colitis.
Background There are no prospective trials comparing the two main reconstructive options after colectomy for Ulcerative colitis, ileal pouch anal anastomosis and ileorectal anastomosis.
- Conditions
- Ulcerative Colitis, Inflammatory Bowel Diseases, Ileostomy - Stoma
- Trial name
- CRUISE (NCT05628701)
- Testing
- Ileorectal anastomosis (IRA), Ileal pouch anal anastomosis (IPAA), ileostomy
- Where
- 4 sites in Sweden, United Kingdom
- Volunteers
- 100 people
- Sponsor
- Linkoeping University
Self Esteem
SIA - Internet-administered CBT for Adolescents With Low Self-esteem
The study will investigate a novel CBT based treatment approach for low self-esteem among adolescents.
- Trial name
- NCT04737356
- Testing
- Cognitive behavior therapy
- Where
- Sweden
- Volunteers
- 52 people
- Sponsor
- Linkoeping University
Loneliness
Guided Online Self-help for Loneliness
The study seeks to investigate the efficacy of two internet-based self-help programmes administered with support from a therapist.
- Trial name
- NCT03807154
- Testing
- ICBT, IPT
- Where
- Sweden
- Volunteers
- 170 people
- Sponsor
- Linkoeping University
Thyroid Nodule
Benign Thyroid Nodules / Benign Goiter. What Subjective Problems Are Improved With an Operation and Can This be Predicted Preoperatively?
Nodules in the thyroid gland are common. Patients discover these lumps either because of their visible size increase or because of local discomforts such as difficulty swallowing, difficulty breathing or voice changes.
- Trial name
- NCT05526261
- Testing
- Hemithyroidectoy
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Shoulder Pain, Shoulder Impingement Syndrome
SWESS: The SWedish Exercise Shoulder Study in Primary Care for Patients With Subacromial Pain
Objective: A randomized clinical trial in order to evaluate the efficacy of a specific exercise strategy for patients with subacromial pain.
- Conditions
- Shoulder Pain, Shoulder Impingement Syndrome, Disorder of Rotator Cuff, Subacromial Bursitis
- Trial name
- SWESS (NCT01885377)
- Testing
- Specific exercise group, Control exercise group
- Where
- Sweden
- Volunteers
- 164 people
- Sponsor
- Linkoeping University
Workplace
Convergence Dialogue Meeting With or Without Neck-specific Exercise Promoting Work Ability
The study will be conducted at workplaces, where the work environment and tasks increase employee risk of developing neck problems.
- Trial name
- WORKCIT (NCT04928989)
- Testing
- convergence dialogue meeting
- Where
- 2 sites in Sweden
- Sponsor
- Linkoeping University
Child Health
Partnering for Change in Sweden - Intervention to Increase Pupils' Engagement and Participation
This project implements an innovative and intersectional collaborative intervention model that addresses challenges that exist for children with special educational needs, who risk school failure, exclusion and poor health.
- Trial name
- NCT05435937
- Testing
- Partnering for change (P4C-Swe), Treatment as usual
- Where
- 3 sites in Sweden
- Volunteers
- 400 people
- Sponsor
- Linkoeping University
Sexual and Gender Minorities, Pregnancy Complications
Physical and Mental Health Among Sexual and Gender Minorities During Pregnancy, Birth and Postpartum
Mental illness increases the risk of adverse birth outcomes (e.g. preterm birth), obstetric complications (e.g. emergency caesarean, birth injuries), and birth trauma.
- Conditions
- Sexual and Gender Minorities, Pregnancy Complications, Obstetric Complication, Psychological Trauma
- Trial name
- NCT05354284
- Testing
- online questionnaire
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Athletic Injuries
Prevention of Lower Limb and Groin Injuries: the Sport Without Injury ProgrammE (SWIPE) Football Trial
This is a three-armed intervention study that evaluates the injury preventive effects of three different training interventions in youth and adult football players.
- Trial name
- SWIPEsoccer (NCT04272047)
- Testing
- Knee Control+ program, Adductor strengthening program, Knee Control program
- Where
- Sweden
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Quality of Recovery, Urology
Postoperative Recovery and Comfort in Patients Undergoing Urologic Robotic Surgery
Previously published studies show that adding intrathecal morphine to general anesthesia can reduce the postoperative pain and length of stay (LOS) in varies types of surgery.
- Conditions
- Quality of Recovery, Urology, Pain, PONV
- Trial name
- NCT04694950
- Testing
- Usual care
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Linkoeping University
Chronic Pain
A Digital Support to Facilitate Sustainable Return to Work for Persons With Chronic Pain and Their Employers
Chronic musculoskeletal pain (CMSP) severely affects the individual's quality of life, functioning and ability to work, and comes with significant societal costs for sick leave and loss of productivity.
- Trial name
- SWEPPE (NCT05058547)
- Testing
- SWEPPE
- Where
- 5 sites in Sweden
- Volunteers
- 360 people
- Sponsor
- Linkoeping University