Clinical trials: sponsored by Lund University
Metabolic Syndrome
Effects of Functional Ingredients in an Acute Metabolic Challenge Context
After an energy-rich meal the blood levels of glucose and lipids undergo a marked temporary increase, triggering a wave of oxidative stress due to the appearance of excess free radicals in adipose and muscle tissues.
- Trial name
- NCT02623608
- Testing
- Reference breakfast, Active Ingredient 1, Active Ingredient 2
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Lund University
Dementia
Technologies to Reduce Caregiver Burden for Informal Caregivers of People With Dementia
This randomized controlled trial aims to recruit a total of 320 dyads composed by persons with dementia living in community settings and their primary informal caregivers.
- Trial name
- TECH@HOME (NCT02733939)
- Testing
- Home monitoring kit
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Lund University
Osteoarthritis, Knee, Osteoarthritis, Hip
Effects of a Structured Digital Osteoarthritis Self-management Program After 6 Months of Adherence
This is a study based on a cohort in a register of patients enrolled in a digital osteoarthritis self-management program, Joint Academy.
- Trial name
- NCT04049318
- Testing
- Education+ exercise (delivered digitally)
- Where
- Sweden
- Volunteers
- 1,709 people
- Sponsor
- Lund University
Type 2 Diabetes, Obesity
Changes in Incretins Response and Glycemic Control After Gastric Bypass Surgery in Type 2 Diabetic Patients Versus Healthy
The purpose of this study is to determine the early changes in gut hormonal, and other metabolites with known relations to the glycemic homeostasis.
- Trial name
- NCT01820273
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lund University
Antibiotic Resistant Infection, Antibiotic Resistant Strain
ESBL in Patients Returning to Sweden With Traveller's Diarrhoea
Patients with traveller's diarrhoea frequently harbour Extended Spectrum Betalactamase (ESBL)-producing Enterobacteriaceae (EPE) returning from EPE-endemic areas.
- Conditions
- Antibiotic Resistant Infection, Antibiotic Resistant Strain, Traveler's Diarrhea
- Trial name
- NCT03866291
- Testing
- No intervention, observational
- Where
- Sweden
- Volunteers
- 305 people
- Sponsor
- Lund University
Coronary Artery Disease, Microcirculation
Aged Garlic Extract Study
The primary intention of the study is to examine the effect of aged garlic extract (AGE) on the absolute change in coronary artery calcium (CAC).
- Conditions
- Coronary Artery Disease, Microcirculation, Biomarkers
- Trial name
- AGE (NCT03860350)
- Testing
- Aged Garlic Extract
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Lund University Hospital
Postoperative Pain
Impact of Gender on Perceived Postoperative Pain
Postoperative pain is a common problem after surgical procedures with many patients afflicted worldwide. Fundamental challenges are the complexity of measuring pain appropriately, and the many associated possible confounders.
- Trial name
- G-PAIN (NCT03968497)
- Testing
- Postoperative pain assessment with female investigator, Postoperative pain assessment with male investigator
- Where
- Sweden
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Lund University
Antibiotic Resistant Infection
Can Probiotic Vivomixx Eradicate Colonization With ESBL?
Can probiotic Vivomixx eradicate Extended Spectrum BetaLactam (ESBL) colonization in adult patients?
- Trial name
- NCT03860415
- Testing
- Vivomixx
- Where
- Sweden
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lund University
Spinal Cord Injuries, Cardiovascular Diseases
The Swedish Spinal Cord Injury Study on Cardiopulmonary and Autonomic Impairment
The main aim of this study is to gain an in-depth knowledge of cardiopulmonary and autonomic health consequences, and related risk factors among people with long-term high-level spinal cord injury.
- Conditions
- Spinal Cord Injuries, Cardiovascular Diseases, Pulmonary Disease, Autonomic Dysfunction
- Trial name
- SPICA (NCT03515122)
- Where
- Sweden
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Lund University
Metabolic Syndrome X, Insulin Resistance
Impact of Meal Order on Postprandial Cardiometabolic Risk Markers
The order in which the different components of a meal are eaten may have impact on the postprandial metabolic responses to carbohydrates, fat and proteins.
- Conditions
- Metabolic Syndrome X, Insulin Resistance, Hyperinsulinism, Glucose Metabolism Disorders
- Trial name
- NCT03358745
- Testing
- Standard meal, bread/butter as starter, Standard meal with soup as starter, Standard meal with cheese as starter
- Where
- 2 sites in Sweden
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Lund University
Prediabetes, Type 1 Diabetes
Diabetes Prevention - Immune Tolerance
A double-blind, randomized investigator-initiated study to determine the safety and the effect of Diamyd® on the progression to type 1 diabetes in children with multiple islet cell autoantibodies Eligible children are 4 years or…
- Trial name
- DIAPREV-IT (NCT01122446)
- Testing
- Diamyd
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Lund University
Type 2 Diabetes
Vildagliptin Versus Dapagliflozin on Glucagon
The aim of the study is to assess if vildagliptin and dapagliflozin have dissociated effects on glucagon secretion after a mixed meal ingestion in metformin-treated subjects with type 2 diabetes and whether this is associated…
- Trial name
- NCT02475070
- Testing
- Vildagliptin, Dapagliflozin
- Where
- Sweden
- Volunteers
- 28 people
- Sponsor
- Lund University
Pain, Postoperative
Pain Evaluation of Venous Cannulation to Predict Postoperative Pain
The investigators have recently reported a relationship between pain induced by peripheral venous cannulation and postoperative pain.
- Trial name
- NCT02982109
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Lund University
Pain
NeoFent-I Study; Fentanyl Treatment in Newborn Infants; a Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Study
The study will assess the efficacy of fentanyl using a pharmacokinetic/pharmacodynamic (PK/PD) model where the concentration of the drug is related to effect curve (pain score change in response to standardized procedural pain).
- Trial name
- NCT03897452
- Testing
- Fentanyl (5 microgram/ml) prediluted ampoules
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Lund University
Glucose Tolerance
Dietary Fibre and Metabolic Benefits
The aim of the project is to study the connection between bacterial fermentation in the colon of prebiotic substrates and effects on systemic metabolism and appetite i healthy humans
- Trial name
- NCT03423381
- Testing
- Cereal product 1, Cereal product 2, Cereal product 3
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Lund University
Amputation, Traumatic, Prosthesis User
Evaluation of a Non-invasive Sensory Feedback System in Hand Prostheses
Implication and evaluation of a non-invasive sensory feedback system in hand prostheses in everyday life.
- Trial name
- NCT03876405
- Testing
- smartskin non-invasive sensory feedback
- Volunteers
- 7 people
- Sponsor
- Lund University Hospital
Microbial Colonization
The Effect of the Fermented Tea Beverage Kombucha on the Oral and Gut Microflora
The purpose of the project is to investigate if consumption of the fermented tea beverage kombucha has an effect on the gut and/or oral microbiota, and further if it depends on the content of living bacteria or is inherent even…
- Trial name
- NCT03873350
- Testing
- Consumption of kombucha, Consumption of heat-sterilized kombucha
- Where
- Sweden
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Lund University
Osteoarthritis
Tai Chi and Hip School for Patients With Hip-OA.
A randomized, controlled study was conducted in southern Sweden with two intervention programs for individuals with X-ray-verified hip osteoarthritis (OA).
- Trial name
- NCT03872869
- Testing
- Hip school or Tai CHi for arthritis
- Volunteers
- 89 people
- Sponsor
- Lund University
Type 2 Diabetes
Sitagliptin and Glucagon Counterregulation
To evaluate the effect of DPP-4 inhibition on glucagon counter-regulatory mechanisms at moderate hypoglycemia in metformin-treated subjects with T2DM
- Trial name
- SITACLAMP (NCT02256189)
- Testing
- Sitagliptin
- Where
- Sweden
- Volunteers
- 28 people
- Sponsor
- Lund University
Hypertension, Cardiovascular Risk Factor
Text Message Intervention for Prevention of Cardiovascular Disease in Primary Care Patients With Hypertension
The primary objective of the study is to examine the impact of lifestyle advices, administered through regularly sent SMS, on hypertension in a primary health care setting.
- Trial name
- PUSH-ME (NCT03442257)
- Testing
- SMS
- Where
- 3 sites in Sweden
- Volunteers
- 59 people
- Sponsor
- Lund University