Clinical trials: sponsored by Lund University
Obesity
Return on Investment on Lap Gastric Bypass Regarding Quality of Life
The purpose of this study is to investigate the cost of treatment and adverse efffects therof corresponds to quality of life improvements and expected wheightloss.
- Trial name
- ROI-LGBP (NCT01986816)
- Where
- Sweden
- Sponsor
- Lund University
Hereditary Breast Cancer
Written Genetic Counseling and Mutation Analysis of BRCA1 and BRCA2 to Patients With Breast Cancer
The overall purpose of the study is to evaluate a method for offering mutation analysis of BRCA1 and BRCA2 to all patients with newly diagnosed breast cancer, regardless of age at diagnosis and family history.
- Trial name
- BRCAsearch (NCT02557776)
- Testing
- Germline genetic testing of BRCA1 and BRCA2
- Where
- 2 sites in Sweden
- Volunteers
- 542 people
- Sponsor
- Lund University
Hemophilia A
Evaluation of a Standardized Protocol for Thrombin Generation Assay
This study is aims at determining the inter laboratory variation when using the thrombin generation assay calibrated automated thrombogram (TGA CAT). It is thus, not a clinical trial in its usual meaning.
- Trial name
- NCT03313531
- Testing
- Thrombin Generation Assay, Treatment with recombinant coagulation factor
- Where
- Sweden
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Lund University
Major Psychiatric Disorder
Balancing Everyday Life - A Lifestyle Intervention for People With Psychiatric Disorders
This is a RCT study, aiming at evaluating the effectiveness of the Everyday Life in Balance (BEL) intervention. The intervention: The BEL was developed on the basis of previous research on lifestyle interventions made by the…
- Trial name
- NCT02619318
- Testing
- Balancing Everyday Life (BEL), Care as usual (generally standard occupational therapy)
- Where
- Sweden
- Volunteers
- 223 people
- Sponsor
- Lund University
Diabetes Mellitus, Depression
Psychological Variables and Hyperglycemia in Diabetes Mellitus
The investigators want to try the psycho educational method "The Affect School with Script Analysis and the physiotherapeutic mind-body therapy "Basal Body Awareness Therapy in patients with diabetes, high HbA1c and psychological…
- Conditions
- Diabetes Mellitus, Depression, Alexithymia, Anxiety
- Trial name
- ALEXIDIAB (NCT01714986)
- Testing
- Affect School, Body Awareness Therapy
- Sponsor
- Lund University
Infertility
Mechanisms of Infertility and Hormonal Changes in Patients With Chronic Kidney Disease
Patients with chronic kidney disease (both men and women), especially those with terminal renal failure, manifest infertility. There has been demonstrated several hormonal changes in patients on dialysis.
- Trial name
- NCT01294904
- Where
- 2 sites in Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lund University
Joint Disease
Key Aspects of Medical Practice in Patients With Haemophilia A
The KAPPa project has the aim to create an international database in which information about clinical features, therapeutic management, burden of illness and costs of severe and moderate haemophilia A patients from different…
- Trial name
- KAPPA (NCT02996942)
- Testing
- Factor VIII replacement
- Sponsor
- Lund University
Diabetes Mellitus, Depression
Psychological Impact in Diabetes: Intervention With Affect School and Basal Body Awareness
Psychological Impact, Metabolic Control, and Biological Stress Markers in Diabetes: Intervention Study With Affect School and Basal Body Awareness Background: Depression is common in patients with diabetes and is associated with…
- Conditions
- Diabetes Mellitus, Depression, Alexithymia, Anxiety
- Trial name
- NCT01498614
- Testing
- Affect School and Basal body awareness
- Where
- Sweden
- Volunteers
- 321 people
- Sponsor
- Lund University
Osteoarthritis
Patient Education Program for Osteoarthritis With Exercise Included
The purpose of this study is to investigate if inclusion of exercise in an education program for patients with osteoarthritis can improve self efficacy, self-perceived health and function.
- Trial name
- PEPOA-E (NCT01119547)
- Testing
- Exercise in a group, Home exercise
- Where
- Sweden
- Sponsor
- Lund University
Accidental Fall, Postural Balance
The Relation Between Movement Patterns, Balance Performance, Function of the Inner Ear and Falls
Falls are one of the most common reasons for immobilisation and death in elderly population. This study aims at studying falls among a group of older people.
- Conditions
- Accidental Fall, Postural Balance, Movement Disorders in Old Age
- Trial name
- NCT03503916
- Where
- Sweden
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Lund University
Breast Cancer Invasive
No Axillary Surgery for Early Breast Cancer.
After breast cancer (BC) screening was introduced for all Swedish women in 1989-90 the number of early invasive BC, clin N0 rose dramatically.
- Trial name
- NCT03669705
- Testing
- Omitting axillary surgery in early breast cancer
- Volunteers
- 1,584 people
- Sponsor
- Lund University
Healthy
Effect of Herbs and Spices on Metabolic Regulation and Appetite in Healthy Subjects
The purpose of the study is to investigate how herbs and spices affect acute/postprandial glucose and insulin responses, inflammatory markers, appetite control peptides, antioxidative capacity, as well as subjective appetite…
- Trial name
- AFC-SPICES (NCT02035241)
- Testing
- Spices 1, Spices 2, Spices 3
- Where
- Sweden
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Lund University
Diabetes Mellitus, Type 1, Remission
Preservation of Residual Beta Cell Mass and Prevention of Celiac Disease in Children With Recent Onset Type 1 Diabetes
The overall aim of this project is to investigate whether a gluten free diet after the onset of type 1 diabetes (T1D) can better preserve the remaining beta cell mass and at the same time prevent the development of Celiac Disease…
- Conditions
- Diabetes Mellitus, Type 1, Remission, Celiac Disease in Children
- Trial name
- Diabglut (NCT03037190)
- Testing
- withdrawal of gluten from the diet
- Where
- Sweden
- Volunteers
- 160 people
- Sponsor
- Lund University
Phantom Limb Pain
Phantom Limb Pain: Efficacy of Non-invasive Sensory Feedback Through the Prosthesis
Amputation of a limb may result from trauma or surgical intervention. The amputation traumatically alters the body image, but often leaves sensations that refer to the missing body part.
- Trial name
- EPIONE (NCT02589080)
- Testing
- Non-invasive sensory feedback
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Lund University Hospital
Type 2 Diabetes
The Swedish Study on Paleolithic Diet for Type 2 Diabetes
Background Paleolithic diet is a modern dietary regimen based on food eaten during the Paleolithic (2.5 million-10.000 years before present); lean meats, fish, shellfish, fruits, vegetables, root vegetables, eggs and nuts.
- Trial name
- SwePaD (NCT01999452)
- Testing
- Paleolithic diet, Diabetes diet
- Where
- Sweden
- Sponsor
- Lund University Hospital
Stroke, Dizziness
Vestibular Rehabilitation for Strokepatients With Dizziness
Recently, the investigators has shown that dizziness is common among patients with first time stroke and that it affects self perceived health.
- Trial name
- NCT01797744
- Testing
- Vestibular rehabilitation
- Where
- Sweden
- Volunteers
- 31 people
- Sponsor
- Lund University
Healthy
Postprandial Effects of Mixed Herbs and Spices on Pathways Associated With Glucose Homeostasis and Inflammation on PBMCs of Healthy Subjects
This study aims to investigate the effect of mixed of herbs and spices on gene expression of pathways associated with glucose homeostasis, oxidative stress, inflammation and its interrelation with circulating miRNA, in the…
- Trial name
- NCT02931643
- Testing
- High fat challenge breakfast, High fat challenge breakfast with mixed-spices
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Lund University
Hypogonadism, Male
Testosterone-Dependent Effects on Protein Biomarkers From Healthy Males
The study is designed to identify and validate new protein biomarkers in blood related to testosterone activity. Thirty healthy young males underwent pharmaceutical castration to lower testosterone levels.
- Trial name
- NCT03541395
- Testing
- GnRH antagonist
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lund University
Hip Fractures
Cluster-randomized Study of 394 Patients Operated With Direct Anterolateral Approach.
394 participants were cluster-randomized during 2010-2014. Depending on which ward the participants admitted to, they were allotted to free rehabilitation (non-precaution group, NPG, n=226) or our conventional regime with…
- Trial name
- NCT03468192
- Testing
- Non-precaution group
- Volunteers
- 394 people
- Sponsor
- Lund University
Diffuse Large B-cell Lymphoma
Valproate as First Line Therapy in Combination With Rituximab and CHOP in Diffuse Large B-cell Lymphoma
Patients with previously untreated diffuse large B-cell lymphoma will receive standard treatment with R-CHOP (rituximab,cyclosphosphamide, doxorubicin, vincristine, and prednison) for 6 cycles, cycle length is 14 or 21 days.
- Trial name
- VALFRID (NCT01622439)
- Testing
- Valproate, Rituximab, Cyclophosphamide
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Lund University Hospital