Clinical trials: sponsored by Lund University
Healthy Subjects
On the Impact of Common Sweetening Agents on Glucose Regulation, Cognitive Functioning and Gut Microbiota
The study intention is to investigate, in healthy humans, effects of 3 commonly used sweeteners on cardiometabolic risk markers, cognitive functions, and influences on gut microbiota composition.
- Trial name
- NCT02580110
- Testing
- Sucrose, Stevia glycosides, saccharin
- Where
- Sweden
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Lund University
Healthy Subjects
Effects of Barley Based Food Products on Metabolism and Gut Microflora
The main objective is to investigate gut microflora composition in relation to cardiometabolic risk markers, and to investigate the effects of 3 days intervention with a barley kernel based product on these variables.
- Trial name
- NCT02427555
- Testing
- Barley kernel bread, white wheat bread
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lund University
Type 2 Diabetes Mellitus
Pre-meal Protein Drink Improve Glycemic Regulation
The purpose of this study is to investigate if a pre-meal drink containing proteins can positively influence glycaemic control in patients with type 2 diabetes mellitus. Comparison with a placebo is included.
- Trial name
- PMB/T2D (NCT01987674)
- Testing
- Pre-meal protein drink, Water drink
- Where
- Sweden
- Volunteers
- 35 people
- Sponsor
- Lund University
Neck Pain
Effects of Qigong and Exercise Therapy Among Patients With Chronic Neck Pain
A randomized controlled, multicenter trial comparing qigong and exercise therapy concerning pain intensity, treatment expectations, disability, neck movements and quality of life in subjects with non-specific, long-term NP after…
- Trial name
- QII (NCT02724826)
- Testing
- Qigong therapy, Exercise therapy
- Volunteers
- 122 people
- Sponsor
- Lund University
Family Health
Early Group Based Parental Support Within Child Health Service - Group Leadership
All parents in Sweden are offered group based parental support within Child Health Service (CHS) but only 40% participate. Nurses feel insecure in their group leadership and express a need for education in group leadership and…
- Trial name
- NCT02494128
- Testing
- Education
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Lund University
HIV Infection, Tuberculosis
Screening for Tuberculosis in HIV-infected Patients Eligible for Antiretroviral Treatment
Background: Increased access to antiretroviral therapy (ART) in Africa will require decentralization to primary health care. For this purpose, adapted methods for management of patients co-infected with tuberculosis (TB) and HIV…
- Trial name
- NCT01433796
- Where
- 5 sites in Ethiopia
- Volunteers
- 812 people
- Sponsor
- Lund University
Obesity
The Effect of Beverages Varying in Protein Quantity on Appetite and Energy Intake
Over the last decades, changes in the diet and lifestyle have led to overall energy imbalance becoming commonplace and the emergence of an obesity epidemic with more than 1.6 billion adults being overweight.
- Trial name
- NCT01849302
- Testing
- Beverages varying in macronutrient content on appetite
- Where
- Sweden
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Lund University
Obesity
The Effect of Breakfasts Varying in Protein Source on Appetite and Energy Intake
Over the last decades, changes in the diet and lifestyle have led to overall energy imbalance becoming commonplace and the emergence of an obesity epidemic with more than 1.6 billion adults being overweight.
- Trial name
- NCT02573194
- Testing
- Breakfasts varying in protein source content on appetite
- Where
- Sweden
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Lund University
B-cell Lymphoma
High Dose, Absorbed Dose Adjusted 90Y-ibritumomab With Peripheral Blood Stem Cells (PBSC) Support in B-cell Lymphoma
90Y-ibritumomab given with stem cells support, based on absorbed dose escalation to the liver. Absorbed dose escalation starts at 12 Gy and is capped at 36 Gy to the liver.
- Trial name
- HITT (NCT00761384)
- Testing
- 90Y-ibritumomab
- Where
- Sweden
- Volunteers
- 7 people
- Sponsor
- Lund University Hospital
Healthy
Effects of Berry Peel Intake on Glucose Metabolism in Healthy Subjects
The main objective of this study is to investigate the effect of a 4-weeks intake of berry peel powder on fasting and postprandial glucose metabolism and inflammatory markers.
- Trial name
- NCT02533986
- Testing
- Berry peel drink, Control drink
- Where
- Sweden
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Lund University
Type 2 Diabetes
Effect of the DPP-4 Inhibitor Sitagliptin on Islet Function After Mixed Meal in Patients With Type 2 Diabetes
study hypothesis to examine the acute effects on glycaemia and islet hormone secretion of increased levels of endogenous GLP-1 and GIP on islet cell function in men with type 2 diabetes.
- Trial name
- NCT01901861
- Testing
- Sitagliptin
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Lund University
Type 2 Diabetes
Study on Lixisenatide and Counterregulation to Hypoglycemia
In hypoglycemia, there is a counterregulation to restore glucose levels. An important part of this counterregulation is the release of the hormone glucagon.
- Trial name
- NCT02020629
- Testing
- Lixisenatide
- Where
- Sweden
- Volunteers
- 18 people
- Sponsor
- Lund University
Metabolic Syndrome, Insulin Resistance
An Antiinflammatory Diet as Modulator of Cardiometabolic Risk and Body Weight in Healthy Subjects
Main scientific question: A previous intervention with an anti-inflammatory multifunctional dietary portfolio (MFD) showed remarkable reductions in cardiometabolic (CM) risk markers compared with a well-designed control diet.
- Conditions
- Metabolic Syndrome, Insulin Resistance, Overweight
- Trial name
- NCT02148653
- Testing
- Multifunctional diet (MFD), Control diet
- Where
- Sweden
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Lund University
Healthy
Acute Effects of Spices on Pathways Associated With Glucose Homeostasis and Inflammation on PBMCs of Healthy Subjects
This study aims to investigate the effect of spices on gene expression of pathways associated with glucose homeostasis, oxidative stress and inflammation, in the postprandial phase in healthy human subjects.
- Trial name
- NCT02479334
- Testing
- Fat challenge breakfast, Fat challenge breakfast+spices, Carbohydrate challenge breakfast
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Lund University
Postprandial Blood Glucose Regulation
Effects on Metabolism and Cognitive Functions of a Commonly Used Commercial Food Supplement
This project evaluate effects of a commonly used food supplement on glucose metabolism and cognitive function.
- Trial name
- NCT02392819
- Testing
- Panax ginseng
- Where
- Sweden
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Lund University
Enrichment With Meaning-generating Activities, Rehabilitation as Usual
Enrichment of Day Centers in Community-based Psychiatry
This RCT study addresses the topic of improving the possibilities for people with severe mental illness (SMI) to be engaged in meaningful daily occupations at community-based activity (CBA) centers.
- Trial name
- NCT01732575
- Testing
- Enrichment with meaning-generating activities
- Volunteers
- 107 people
- Sponsor
- Lund University
Obesity, Metabolic Syndrome
Over-night Effect of Dietary Fiber on Glucose Metabolism and Satiety
The experimental model is a semi-acute, over-night, study where the purpose is to evaluate food factors related to colonially derived regulation and satiety in healthy subjects.
- Trial name
- NCT02347293
- Testing
- High levels of indigestible carbohydrates, Low levels of indigestible carbohydrates
- Where
- Sweden
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Lund University
Colorectal Cancer
Avastin and Chemotherapy Followed by a KRAS Stratified Randomization to Maintenance Treatment for First Line Treatment of Metastatic Colorectal Cancer.
Patients with metastatic colorectal cancer will be treated with chemotherapy according to investigators choice. In addition to chemotherapy treatment, treatment with bevacizumab will be given concomitantly.
- Trial name
- ACT2 (NCT01229813)
- Testing
- bevacizumab, erlotinib, bevacizumab, low dose capecitabine
- Where
- 12 sites in Denmark, Sweden
- Volunteers
- 233 people
- Sponsor
- Lund University Hospital
Wrist Fractures, Dizziness
Vestibular Rehabilitation for Patients With Fall-related Wrist Fractures
Dizziness has been identified as a risk factor for fall and vestibular asymmetry has been found among patients with fall-related wrist fractures as well as among patients with hip-fracture.
- Trial name
- NCT00988572
- Testing
- Vestibular rehabilitation
- Where
- Sweden
- Volunteers
- 82 people
- Sponsor
- Lund University
Osteoarthritis in the Hip, Knee and Hand
Effect of an Education Programme for Patients With Osteoarthritis in Primary Care - a Randomized Controlled Trial
Osteoarthritis is a common disease. The core treatment is often patient education. The aim of this study is therefore to study the effect of a patient education programme for patients with osteoarthritis in primary health care.
- Trial name
- NCT00979914
- Testing
- Patient education programme
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Lund University