Clinical trials: sponsored by Lund University
Diabetes, Hypoglycemia
Vildagliptin and the Glucagon Response to Hypoglycemia in Type 1 Diabetes
The study examines whether DPP-4 inhibition by vildagliptin affects the glucagon counterregulatory response to hypoglycemia in type 1 diabetes.
- Trial name
- NCT01147276
- Testing
- Vildagliptin
- Where
- Sweden
- Volunteers
- 28 people
- Sponsor
- Lund University
Endocrine Dysfunction, Cerebral Infarctions
Endocrine Dysfunction and Quality of Life After Subarachnoid Hemorrhage
Investigation of the incidence of endocrine dysfunction following subarachnoid hemorrhage (SAH), and to see if this has a relation to CNS lesions as evaluated by MRI and to common symptoms after SAH such as general exhaustion…
- Conditions
- Endocrine Dysfunction, Cerebral Infarctions, Quality of Life
- Trial name
- NCT01101711
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Lund University Hospital
Diabetes Mellitus, Type 2, Satiety Response
Metabolic Effects of a Pre-meal Protein Drink With or Without Added Amino Acids at a Subsequent Composite Meal
The purpose of the study was to investigate the efficacy of intake of whey or soy protein isolates, respectively, with or without supplementation of amino acids, on post-meal insulin secretion and glycaemic regulation.
- Trial name
- NCT01586780
- Testing
- Protein drink, Reference meal
- Where
- Sweden
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Lund University
Breast Cancer, Postmenopausal
Study of Statin as Neo-Adjuvant Therapy in Postmenopausal Breast Cancer
The purpose of this study is to monitor: Tumor biological alterations following two weeks of neo-adjuvant statin therapy. Effects of statins on tumor proliferation. Functional studies on the mevalonate pathway.
- Trial name
- NCT00816244
- Testing
- Atorvastatin
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Lund University Hospital
Healthy, Abnormal Vascular Flow
Racemic Ketamine Versus S-ketamine With Arterial Spin Labeling (ASL)-MRI in Healthy Volunteers
Racemic ketamine and S-ketamine are used in clinical practice today. Little is known of their difference in effect on cerebral blood flow, volume and metabolism.
- Trial name
- NCT01506921
- Testing
- Racemic ketamine, S-ketamine
- Where
- Sweden
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Lund University
Vitamin D Deficiency
Alternative Treatments of Vitamin D Deficiency
The purpose of the study is to compare the efficiency of UVB and vitamin D supplementation in treatment of vitamin D deficiency.
- Trial name
- NCT01512537
- Testing
- Narrowband UVB, Vitamin D and calcium
- Where
- Sweden
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Lund University
Stomach Cancer, Gall Bladder Cancer
Study of Capecitabine and Oxaliplatin in Combination With Radiotherapy in Patients With Unresectable Gastro-Intestinal Cancer
The purpose with this study is to evaluate treatment with radio chemotherapy (oxaliplatin and capecitabine) given concommitant with radiotherapy in patients with gastrointestinal tumors.
- Conditions
- Stomach Cancer, Gall Bladder Cancer, Bile Ductus Cancer, Pancreas Cancer
- Trial name
- CORGI (NCT01016639)
- Testing
- oxaliplatin, capecitabine, radiotherapy
- Where
- 5 sites in Sweden
- Volunteers
- 106 people
- Sponsor
- Lund University Hospital
Obesity
Antidiabetic Properties of Rose Hip
The purpose of this study is to determine whether daily intake of a drink containing rose hip powder reduces risk markers of type diabetes and cardiovascular disease.
- Trial name
- NCT01316016
- Testing
- Rose hip
- Where
- Sweden
- Volunteers
- 31 people
- Sponsor
- Lund University
Recurrent Acute Otitis Media
Pneumococcal Vaccination of Otitis-prone Children
Acute otitis media (AOM) is a common childhood disease, which becomes recurrent in 15-20% of the cases. Streptococcus pneumoniae is one of the leading causative agents, and a small reduction in the number of AOM episodes has been…
- Trial name
- NCT01263210
- Testing
- Prevenar
- Where
- Sweden
- Volunteers
- 109 people
- Sponsor
- Lund University Hospital
Diabetes, Autoimmune, Diabetes Mellitus, Adult-Onset
Early Insulin Treatment in Patients With Latent Autoimmune Diabetes
Among adult patients diagnosed with type 2 diabetes, about 6% have autoantibodies directed against the insulin producing beta cells in the pancreas.
- Trial name
- NCT01109927
- Testing
- Insulin
- Volunteers
- 42 people
- Sponsor
- Lund University Hospital
Premature Birth
Balanced Anesthesia for Intubation of Premature Infants
The study aim is to compare a balanced anesthesia of the medicines used in all other age groups with the routine premedication in use for premature's with regards to the success in the intubation procedure, the need for analgesia…
- Trial name
- NCT00216944
- Testing
- Tracheal intubation for respiratory care in preterm infants
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Lund University Hospital
Hypoglycemia, Hyperglycemia
Influence of Dietary Fiber-rich Meals on Gene Expression and Postprandial Glucose and Lipid Response
The aim of this study is to Measure the effect on gene expression in leukocytes from a meal rich in oat bran Investigate the postprandial glucose, insulin and triglyceride responses after intake of meals containing fiber from…
- Trial name
- NCT01005342
- Testing
- Oat bran, Spray-dried oat drink, Rye bran
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Lund University
Human Papillomavirus Infection, Cervical Intraepithelial Neoplasia
Use of Human Papillomavirus Persistence for Determination of Treatment Efficacy Among Women With Cervical Dysplasia
The objectives are to evaluate the effectiveness of treatment of cervical intraepithelial neoplasia (CIN) by loop electrosurgical excision procedure using persistence of human papillomavirus (HPV) as outcome, and to perform a…
- Trial name
- NCT00931190
- Where
- Sweden
- Volunteers
- 195 people
- Sponsor
- Lund University
Infantile Colic
Acupuncture in Infantile Colic
The purpose of this study is to investigate whether acupuncture influences: the rate of infants who still fulfil the colic criterion after three intervention weeks the time when the infants are crying, fussing or have intense…
- Trial name
- NCT00860301
- Testing
- Acupuncture
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Lund University
Persistent Pulmonary Hypertension, Respiratory Distress Syndrome
Treatment of Elevated Arterial Pulmonary Pressure With Inhaled Iloprost
The purpose of this study is to determine if iloprost is effective in the treatment of elevated arterial pulmonary pressure in children with ventilator treated respiratory distress syndrome.
- Trial name
- NCT00216931
- Testing
- iloprost
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Lund University Hospital
Healthy
Effect of Commercial Rye Whole-Meal Bread on Postprandial Blood Glucose and Gastric Emptying in Healthy Subjects
Increased intake of dietary fibre and whole grains is related to reduced risk of developing diabetes. The term "whole grain" is often used for whole-meal products in which the structure of the cereal grain is destroyed in the…
- Trial name
- NCT00779298
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lund University Hospital
Diabetes Mellitus, Type 2
Paleolithic Diet in the Treatment of Diabetes Type 2 in Primary Health Care
There is uncertainty about the optimal diet in the prevention and treatment of diabetes type 2. Earlier studies have generally focused on intakes of fat, protein, carbohydrate, fiber, fruit and vegetables.
- Trial name
- NCT00435240
- Testing
- Paleolithic diet
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Lund University Hospital
Perineal Lacerations
Ritgens Maneuver for the Prevention of Anal Sphincter Tears at Delivery: A Randomized Controlled Trial
The aim of the investigation was to assess whether routine use of the modified Ritgen´s maneuver decreases the risk of anal sphincter injury at delivery, compared with simple manual protection of the perineum.Ritgen´s maneuver…
- Trial name
- NCT00652977
- Testing
- Ritgens maneuver, Standard care (Manual support of the perineum)
- Where
- 2 sites in Sweden
- Volunteers
- 1,623 people
- Sponsor
- Lund University Hospital
Cardiovascular Diseases
Incidence of Cardiovascular Diseases in Patients With Hypopituitarims
The aim of the present study was therefore two-fold: 1) to make a retrospective comparison of incidence of non-fatal stroke and cardiac events between a large cohort of patients with confirmed GHD on replacement therapy…
- Trial name
- NCT00442858
- Volunteers
- 800 people
- Sponsor
- Lund University Hospital