Clinical trials: sponsored by Lund University
Heart Failure
Selfcare Management Intervention in Heart Failure
A novel tool for self-care enhancement for heart failure (HF) patients has been developed. In this randomized controlled trial, patients will be randomized 1:1 to either receive the home-based tool (OPTILOGG) or standard care.
- Trial name
- SMART-HF (NCT03484286)
- Testing
- OPTILOGG, Standard care
- Where
- Sweden
- Volunteers
- 124 people
- Sponsor
- Lund University
Chronic Pain
Self-Management of Chronic Pain
The investigators aim to validate if a digital tool for increased self-management of chronic pain can improve the quality of life for patients with chronic pain.
- Trial name
- NCT04837794
- Testing
- Digital Pain-Management Tool
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Lund University
Osteoarthritis, Knee, Osteoarthritis, Hip
Active@Work - Optimizing Physical Activity at Work.
The aim of this project is to explore if monitoring physical activity including feedback can have any effect on physical activity level, function, work ability, health related quality of life or work productivity among…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Physical Activity
- Trial name
- NCT03354091
- Testing
- FitBit Flex 2
- Where
- Sweden
- Volunteers
- 160 people
- Sponsor
- Lund University
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Haploidentical Stem Cell Transplantation for Children With Therapy Resistant Leukemia
Despite substantial progress in the treatment pediatric acute leukemia a significant number of children will experience primary or secondary resistance to the treatment.
- Trial name
- NCT01025778
- Testing
- Clofarabine for remission induction, Etoposide for remission induction, Cyclophosphamide for remission induction
- Where
- Sweden
- Volunteers
- 7 people
- Sponsor
- Lund University Hospital
Neuroblastoma
Haploidentical Stem Cell Transplantation in Neuroblastoma
Children with primary resistant or relapsed neuroblastoma who do not achieve remission with conventional chemotherapy have extremely dismal prognosis.
- Trial name
- NCT00790413
- Testing
- iodine I 131 metaiodobenzylguanidine, Fludarabine, Thiotepa
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Lund University Hospital
Stroke
Sensory Re-learning of the Upper Limb After Stroke
The overall aim of this study is to investigate if sensory re-learning in combination with task-specific training is more effective than task-specific training alone to improve sensory function of the hand, dexterity, the ability…
- Trial name
- SENSUPP (NCT03336749)
- Testing
- Sensory group, Control group
- Where
- Sweden
- Volunteers
- 27 people
- Sponsor
- Lund University
Colorectal Cancer
Peripheral Neuropathy in Colorectal Cancer Patients Under Adjuvant Chemotherapy With FOLFOX, FLOX or XELOX Regime
Oxaliplatin is a cytotoxic platinum compound and is one of the chemotherapeutic agent used in advanced colorectal cancer. It is used combined with Fluorouracil (5 FU) and Leucovorin.
- Trial name
- PENCOLA (NCT03542136)
- Testing
- VibrosSense Meter®
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Lund University Hospital
End Stage Kidney Disease, Chronic Kidney Disease Requiring Chronic Dialysis
Optimized vs. Standard Automated Peritoneal Dialysis Regimens Study
This clinical study is designed to evaluate the theoretical prediction of a lower glucose absorption in optimized automated peritoneal dialysis regimes.
- Trial name
- OptiStAR (NCT04017572)
- Testing
- Automated peritoneal dialysis (APD)
- Where
- Argentina
- Volunteers
- 21 people
- Sponsor
- Lund University
Postprandial Glucose Regulation
Health Effects of Oat and Oat Bioactive in Human
Aim of the study is to investigate health effects of oats and oat derived components, in human intervention studies, with the purpose to build new knowledge for development of cardiometabolic protective foods
- Trial name
- NCT04542265
- Testing
- Effects of Oat and Oat Components on Cardiometabolic risk variables
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lund University
Diabetes Mellitus, Type 1, Prediabetic State
Prevention Trial: Immune-tolerance With Alum-GAD (Diamyd) and Vitamin D3 to Children With Multiple Islet Autoantibodies
The purpose of this study is to evaluate if immune-tolerance with Alum-formulated GAD (Diamyd), in combination with high dose Vitamin D3, may delay or stop the autoimmune process leading to clinical type 1 diabetes in…
- Trial name
- DiAPREV-IT2 (NCT02387164)
- Testing
- Alum-GAD, Vitamin D3
- Where
- Sweden
- Volunteers
- 26 people
- Sponsor
- Lund University
Ageing
Implementation of Knowledge-Based Palliative Care
The research on ageing during the last couple of decades has increasingly focused on questions regarding the quality of life and life satisfaction of the old people.
- Trial name
- KUPA (NCT02708498)
- Testing
- Educational Intervention
- Where
- 30 sites in Sweden
- Volunteers
- 1,151 people
- Sponsor
- Lund University
Activities of Daily Living, Cost Effectiveness
Evaluation of Housing Adaptations and Mobility Devices
The rationale underlying this project is the fact that HA is a very common compensatory interven¬tion within municipality health care, undertaken to support an independent living in the own home.
- Conditions
- Activities of Daily Living, Cost Effectiveness, Housing
- Trial name
- FORMASEvid (NCT01960582)
- Testing
- New Practice Strategy
- Where
- Sweden
- Volunteers
- 340 people
- Sponsor
- Lund University
Fractures, Bone, Fragility
Factors Associated With Future Fractures in Middle-aged Men and Women
From prospectively collected health and life-style data and anthropometric data in the Malmo Diet and Cancer (MDC) cohort identify factors that predicts or are associated with forthcoming fracture in middle-aged men and women.
- Conditions
- Fractures, Bone, Fragility, Life Style
- Trial name
- MDCFract (NCT04151732)
- Testing
- Physical activity, alcohol, tobacco, Hormonal factors, Cardiovascular disease
- Where
- Sweden
- Volunteers
- 30,351 people, healthy volunteers welcome
- Sponsor
- Lund University
Microbial Colonization
Impact of Quinoa Milk Fermented With Lactic Acid Bacteria From Foods on Human Oral and Intestinal Flora
The demand for alternatives to dairy products has increased in recent years and a lot of proposals for vegetable milk and yogurt products have taken place in the market.
- Trial name
- NCT04280731
- Testing
- fermented quinoa
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lund University
Glucose Tolerance, Appetite Sensations
Effects of Nopal Fractions on Postprandial Glucose Regulation and Appetite Variables in Healthy Humans
Postprandial effects of Nopal fractions on glucose and appetite regulation will be investigated in healthy humans, in a randomised controlled crossover trial
- Trial name
- NCT04439630
- Testing
- Nopal fractions, Test product without the active components
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Lund University
Vestibular Schwannoma
Gentamicin Treatment Prior to Schwannoma Surgery - No Residual Function
The purpose of the study is to determine whether vestibular and postural compensation following schwannoma surgery is improved by ablating vestibular function prior to surgery, even if vestibular function is absent according to…
- Trial name
- NCT02415257
- Testing
- Gentamicin
- Where
- Sweden
- Sponsor
- Lund University
Vestibular Schwannoma
Gentamicin Treatment Prior to Schwannoma Surgery - Residual Function
The purpose of the study is to determine whether vestibular and postural compensation following schwannoma surgery is improved by ablating remaining vestibular function prior to surgery, through gentamicin injections in the…
- Trial name
- NCT02379754
- Testing
- Gentamicins
- Where
- Sweden
- Sponsor
- Lund University
Knee Injury, Knee Osteoarthritis
Monitoring Of Helsingborg Acute Knee Injuries (MOHAK)
Using magnetic resonance imaging (MRI), laboratory analyses and patient reported outcomes, the overall aim of this study is to investigate structural injuries and biochemical alterations in the acutely injured knee and to relate…
- Trial name
- NCT01382173
- Where
- Sweden
- Volunteers
- 192 people
- Sponsor
- Lund University
Intracranial Tumor
Treatment Effects Inclusive Cognitive Impact and Possibilities to Individually Adjusted Treatment in Patients With Intracranial Tumors With Clinical, Neuropsychological and Imaging Parameters
The main purposes with this trial is to investigate the potential of MRI with diffusion and blood volume, flow in brain to diagnose and to measure treatment effects in patients with intracranial tumors, especially gliomas and…
- Trial name
- NCT01674582
- Testing
- MRI, neuropsychological evaluation, blood sampling
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Lund University Hospital
Anorexia Nervosa, Anorexia Nervosa, Atypical
Implementation of Evidence-Based Treatment of Restrictive Eating Disorder With Pronounced Starvation
In the Region Skåne in Sweden, the investigators have developed guidelines for providing intensive and evidence-based treatment during the first month in case of severe restrictive eating disorder with pronounced starvation.
- Conditions
- Anorexia Nervosa, Anorexia Nervosa, Atypical, Avoidant/Restrictive Food Intake Disorder, Starvation
- Trial name
- ROCKETLAUNCH (NCT04060433)
- Testing
- Family Therapy
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Lund University Hospital