Clinical trials: sponsored by Mansoura University
Tympanoplasty
Role of Hyaluronic Acid Gel as an Adjunct to Temporalis Facia Graft in Tympanoplasty for Total Tympanic Membrane Perforation
Aim: the aim of the study is to compare the results of tympanoplasty using hyaluronic acid gel as an adjunct to temporalis fascia graft with tympanoplasty using temporalis fascia graft.
- Trial name
- NCT07233226
- Testing
- Tympanoplasty using hyaluronic acid gel as an adjunct to temporalis fascia, Tympanoplasty using temporalis fascia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Chronic Kidney Failure, End-Stage Renal Disease
Effect of Isometric Hand Grip Exercises Using a Dynamometer on AV Fistula Maturation and Patency in Hemodialysis Patients
Patients with chronic kidney failure who require hemodialysis depend on a surgically created connection between an artery and a vein in the arm, known as an arteriovenous fistula.
- Conditions
- Chronic Kidney Failure, End-Stage Renal Disease, Arteriovenous Fistula
- Trial name
- NCT07238855
- Testing
- Isometric Hand-Grip Exercise Training Using a Hand Dynamometer
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Mansoura University
Dental Caries, Prevention
Sealant Application by Interns After Tele-demonstration
Abstract Background: Dental caries remains a major public health issue worldwide, particularly among children. Pit and fissure sealants represent a high-quality, evidence-based preventive measure.
- Conditions
- Dental Caries, Prevention, Education
- Trial name
- TESS (NCT07232797)
- Testing
- tele-demonstration, traditional demonstration group
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
COVID-19 Pneumonia
High Velocity Nasal Insufflation Versus Continuous Positive Airway Pressure in COVID 19 Pneumonic Patients
compare the efficacy of High-Velocity Nasal Insufflation (HVNI) versus Continuous Positive Airway Pressure (CPAP) in managing COVID 19 pneumonic patients with acute type 1 respiratory failure
- Trial name
- NCT07213518
- Testing
- High Velocity Nasal Insufflation, Continuous Positive Airway Pressure
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Mansoura University
Pulmonary Arterial Hypertension
Safety and Efficacy of Nebulized Nitroglycerin in Pulmonary Arterial Hypertension
The 6th World Symposium on Pulmonary Hypertension, pre-capillary pulmonary hypertension (PH) has been defined as mean pulmonary arterial pressure (mPAP) >20 mm Hg with a pulmonary arterial wedge pressure (PAWP) ≤15 mm Hg and…
- Trial name
- NCT07214129
- Testing
- Nebulized nitroglycerin
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Vital Pulp Therapy
Vital Pulp Therapy With Different Materials for Young Permanent Teeth
This study will be conducted to: Evaluate clinically and radiographically apexogenesis in immature permanent molars using: 1. Calcium Hydroxide. 2. MTA. 3. Laser. 4. Laser combined with MTA.
- Trial name
- NCT05498337
- Testing
- calcium hydroxide, MTA, Diode Laser
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Safety Issues
Effect of Lean Leadership Training Program on Head Nurses' Lean Performance and Staff Nurses' Workplace Safety at Mansoura Children Hospital
Effect of Lean Leadership Training Program on Head Nurses' Lean Performance and Staff Nurses' Workplace Safety at Mansoura Children Hospital
- Trial name
- leadership (NCT06989294)
- Testing
- Lean Leadership
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Respiratory Distress Syndrome (Neonatal)
Open-label Randomized Controlled Trial of Two Protocols for Weaning From High Frequency Oscillatory Ventilation in Preterm Neonates With Respiratory Distress Syndrome Admitted in the NICU of Mansoura University Children Hospital
Our study is a randomized controlled trial that compares two weaning protocols of preterm infants with respiratory distress syndrome who are ventilated on high frequency oscillatory ventilation in order to establish the best…
- Trial name
- NCT07202299
- Testing
- HFOV weaning protocol 1, HFOV weaning protocol 2
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University Children Hospital
Vitamin D Deficiency, Implant Assesment
Effect of Vitamin D on the Clinical and Radiographic of Unsplinted Mandibular Implant Overdentures
This study investigates the effect of vitamin D on bone loss around mandibular implant overdentures. Bone levels around implants will be measured to understand how vitamin Daffect the health of implant-supported dentures.
- Conditions
- Vitamin D Deficiency, Implant Assesment, Radiography, Clinical and Radiographic Effect
- Trial name
- Vit D and bone (NCT07200011)
- Testing
- Observational: Serum Vitamin D Levels
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Nocturnal Enuresis in Children
Omegapres Versus Solifenacin and Mirabegron Combination Therapy in Treatment of Primary MNE
The goal of this clinical trial is to compare combination of Solifenacin and MIrabegron in treatment of primary mono-symptomatic nocturnal enuresis in children. It will also learn about the safety of that combination.
- Trial name
- NCT07199894
- Testing
- Mirabegron (beta3-adrenoceptor agonist), Anticholinergics, Desmopressin (DDAVP)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Maternal Breastfeeding Experience, Maternal Breastfeeding Comfort
Laid Back Breastfeeding Position on Breastfeeding Experience
The goal of this clinical trial is to evaluate the effect of laid back breast feeding position on breastfeeding experience among multiparous women.
- Trial name
- LBB/PBE (NCT07196202)
- Testing
- Laid-Back position training, Standard Postpartum Care
- Where
- 2 sites in Egypt
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Tracheal Stenosis, Subglottic Stenosis
Slide Tracheoplasty Versus Tracheal Resection Anastomosis in Acquired Tracheal Stenosis
Aim of the Work To compare the clinical outcomes between patients will undergo slide tracheoplasty and those will undergo tracheal resection anastomosis for acquired tracheal stenosis.
- Trial name
- NCT06917222
- Testing
- Slide tracheoplasty, Tracheal resection anastomosis
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University Hospital
Normal Vaginal Delivery, Perineal Episiotomy
Effect of Perineal Cryotherapy on Episiotomy
The present study aims to evaluate the effect of perineal cryotherapy on episiotomy- associated pain among postpartum women. The study hypothesis: Post-partum women who apply perineal cryotherapy have lower level of episiotomy…
- Trial name
- NCT06921200
- Testing
- Cryotherapy
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Completely Edentulous, Implant Assesment
Fully Versus Partially Guided Implants Placement: Measurement of Accuracy of Implant Position and Passivity of Superstructures.
compare fully versus partially guided all on four implants placement immediately loaded by maxillary and mandibular screw retained overdentures: A radiographic and photogrammetric measurement of accuracy of implant position and…
- Trial name
- NCT07174791
- Testing
- cone beam computed tomography, photogrammetric scan using elite scanner (shining 3d)
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Chronic Rhinosinusitis (Diagnosis)
Role of Nanoemulsified Sesame Oil in Post-operative Care After Endoscopic Sinus Surgery
The goal of our thesis is to design, develop and characterize a novel thermodynamically stable NE by spontaneous method intended for topical use.
- Trial name
- NCT06437717
- Testing
- application of different topical nasal solutions
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Myopia
Efficacy of Topical Atropine Eye Drops for Control of Myopia Progression Among Children Attending Mansoura University Ophthalmic Center
This randomized controlled trial aims to evaluate the efficacy and safety of low-dose topical atropine sulphate (0.05%), a non-selective muscarinic antagonist, in slowing the progression of myopia and ocular axial elongation in…
- Trial name
- NCT07164092
- Testing
- Atropine 0.05% Eye drops
- Volunteers
- 45 people
- Sponsor
- Mansoura University
Papillary Reconstruction
Papillary Reconstruction Using Three Different Modalities
papillary reconstruction will be done by three techniques : injection of hyaluronic acid in the base of the papilla and booster doses can be required , injection of ALB-PRF which resorbs slowly and so longer effect the last…
- Trial name
- NCT07159802
- Testing
- Papillary reconstruction
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Appendicitis, Hernia
Aromatherapy Versus Acupressure: Impact on Postoperative Pain and Sleep Quality in Pediatric Abdominal Surgery Patients
The study's aim is to examine the effect of using aromatherapy versus acupressure on pain intensity and sleep pattern for children undergoing abdominal surgeries.
- Conditions
- Appendicitis, Hernia, Abdominal Exploration, Splenectomy
- Trial name
- NCT07157501
- Testing
- Accupressure, Aromatherapy inhaler
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Indirect Tooth-colored Onlay Restorations in Posterior Teeth, Clinical Performance of Cervical-margin-relocated Onlay Restorations
Clinical Evaluation of Indirect Tooth-Colored Onlays With Cervical Margin Relocation
This study will evaluate the performance of three different tooth-colored onlay materials in adult patients' posterior teeth. First, investigators will use a bulk-fill composite resin to raise the cavity margin above the gum line…
- Trial name
- NCT07157410
- Testing
- Machinable lithium-disilicate ceramic onlay (IPS e.max CAD), Pressed lithium-disilicate ceramic onlay (IPS e.max Press), Machinable composite onlay (BRILLIANT Crios)
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Bacterial Viability of Necrotic Pulp With Asymptomatic Apical Periodontitis
Molecular Analysis of Intracanal Microbes After Chemomechanical Procedure and Root Canal Medication: A Randomized Controlled Trial
This study aimed to evaluate clinically the intracanal microbes at molecular level after using established root canal medicament Calcium hydroxide and potential root canal medicament Glycyrrhizin.and Decontamination Analysis of…
- Trial name
- NCT06291623
- Testing
- Glycyrrhizin
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
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