Clinical trials: sponsored by Mansoura University
Bacterial Viability of Necrotic Pulp With Asymptomatic Apical Periodontitis
Molecular Analysis of Intracanal Microbes After Chemomechanical Procedure and Root Canal Medication: A Randomized Controlled Trial
This study aimed to evaluate clinically the intracanal microbes at molecular level after using established root canal medicament Calcium hydroxide and potential root canal medicament Glycyrrhizin.and Decontamination Analysis of…
- Trial name
- NCT06291623
- Testing
- Glycyrrhizin
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Pain
The Effectiveness of Sweet Solution Versus Cryotherapy in Reducing Pain During Administration of Local Anesthesia Among Children
the porpose of study to assess The Effectiveness of Sweet Solution Versus Cryotherapy in Reducing Pain During Administration of Local Anesthesia Among Children
- Trial name
- NCT07002528
- Testing
- sucrose solution, Cryotherapy, topical anesthesia
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Cirrhosis, HCC - Hepatocellular Carcinoma
Efficacy & Safety of Anticoagulants in Cirrhosis ± HCC
We will give an anticoagulant against portal vein thrombosis, and watch for the results.
- Conditions
- Cirrhosis, HCC - Hepatocellular Carcinoma, Portal Vein Thrombosis
- Trial name
- NCT07132515
- Testing
- Enoxaparin, warfarrin, or apixaban
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Patient Satisfaction Using Implant Retained Overdentures
Patient's Satisfaction of Mandibular Implant Supported Overdentures With Reduced Denture Base Extensions.
This study aimed to compare reduced (partially extended) denture bases with fully extended bases regarding patient satisfaction, oral health-related quality of life (OHRQoL), and masticatory efficiency.
- Trial name
- NCT06850558
- Testing
- Four parallel implants were installed in the interforaminal region
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Prosthesis Durability
Effect of Geometric Modifications of Implant Scan Bodies
The aim of this clinical study will be the effect of geometric modifications of implant scan bodies compared to conventional transfer techniques on passivity of all on four mandibular restorations
- Trial name
- NCT06040385
- Testing
- Implant supported hybrid prosthesis
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Initial Dental Caries, White Spot Lesion of Tooth
Clinical Evaluation of Remineralizing Potential of Remineralizing Agents on WSLs Managment
To evaluate and compare the clinical effect of four different remineralizing agents on initial enamel caries after a two years follow up.
- Trial name
- NCT07111403
- Testing
- SAP fluoride plus, 10% n-HAp., 10% n-BAG.
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Thoracic Diseases
Thoracic Fluid Content as an Outcome Predictor in Intensive Care Unit
Hemodynamic monitoring is measuring and monitoring the factors that influence the force and flow of the blood. It is an important aspect of patients care in operating rooms and critical care units.
- Trial name
- NCT07100821
- Testing
- Hemodynamic parameters was measured by using electric cardiometry (ICON)
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Mansoura University Hospital
End Stage Renal Disease (ESRD), CKD 5D, Hemodialysis
Activated Charcoal Use in Chronic Kidney Disease Patients
Hyperphosphatemia management is initially based on restricting dietary phosphorus intake. Hyperphosphatemia is almost always seen in patients on dialysis and may contribute to progressive vascular calcification.
- Conditions
- End Stage Renal Disease (ESRD), CKD 5D, Hemodialysis, CKD-MBD - Chronic Kidney Disease Mineral and Bone Disorder
- Trial name
- NCT06906874
- Testing
- Activated Charcoal, Phosphate Binders
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
we Search for the Effect of Ergonomic Practices on Quality of Breastfeeding
Effect of Ergonomic Practices on Quality of Breastfeeding
This study aims to assess the effectiveness of ergonomic practices on quality of breastfeeding among primiparous.
- Trial name
- NCT07098702
- Testing
- educational sessions and booklet, No Interventions
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Digital Intervention
Complete Digital Workflow
This study will aim to clinical evaluation of titanium-zirconium and peek-composite of screw retained prosthesis used for rehabilitation of edentulous patients using Complete digital workflow for construction of full arch implant…
- Trial name
- NCT07091786
- Testing
- Implant supported prosthesis
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Breast Cancer Female, Breast Cancer Patients
Effect of Pentoxifylline on Preventing Chemotherapy-induced Toxicities in Patients With Breast Cancer
This clinical trial is a randomized clinical trial that aims to assess the usefulness of adding pentoxifylline to the neoadjuvant chemotherapy treatment protocol of doxorubicin/cyclophosphamide fllowed by taxane for breast cancer…
- Conditions
- Breast Cancer Female, Breast Cancer Patients, Neoadjuvant Therapy, Doxorubicin
- Trial name
- NCT06186700
- Testing
- Pentoxifylline 400mg plus chemotherapy, Chemotherapy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Patient Satisfaction, Maxilofacial
Evaluation of Patient Satisfaction After the Construction of Maxillary Obturator Prosthesis for Limited Mouth Opening in Maxillofacial Cases : Cross Over Randomized Clinical Trial
A patient's quality of life is frequently negatively impacted by oral cancer, which is a serious condition. Treatment for oral cancer, which includes radiation, chemotherapy, and surgery, can result in several oral complications.
- Trial name
- NCT07079384
- Testing
- The patient will be instructed about wearing the prosthesis. First, seat the prosthesis in a posterior undercut, then rotate the prosthesis slightly superiorly in the defect area and engage the anteri
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Periodontitis Stage II, Gingival Pocket
Use of Injectable Extended Platelet-Rich Fibrin as a Local Drug Delivery in the Treatment of Stage II Periodontitis Patients
The objective of the present study is to assess the clinical effectiveness of local delivery of injectable extended platelet-rich fibrin in subgingival application when used in conjunction with scaling and root planing (SRP) in…
- Trial name
- NCT07080294
- Testing
- extended platelet rich fibrin injection in pocket, albumin injection in pocket, scaling and root planing
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Mansoura University
Gingival Recession, Localized
Extended Platelet- Rich Fibrin Membrane Combined With Vestibular Incision Subperiosteal Tunnel Access Technique to Treat Localized Gingival Recession
This study will be performed to clinically evaluate and compare the effectiveness of extended platelet-rich fibrin (e-PRF) membrane versus de-epithelized free gingival graft (DFGG) in combination with vestibular incision…
- Trial name
- alb prf REC (NCT07079293)
- Testing
- Preparation of Extended PRF, Harvesting of Free Gingival Graft and preparation of CTG, VISTA technique
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Smoking Cessation
Smoking Among Resident Physician and Their Role in Smoking Cessation Advice
smoking is a key modifiable risk factor that greatly increases the likelihood of 2 dying young from cancer, heart disease, and lung disorders The World Health Organization (WHO) reports that 3 tobacco products are used by…
- Trial name
- NCT07075263
- Testing
- Questionnaire
- Where
- Egypt
- Volunteers
- 225 people
- Sponsor
- Mansoura University Hospital
Dental Anxiety
Effectiveness Of Magic Tricks Distraction Technique
Dental anxiety among children is a significant challenge in pediatric dentistry, often hindering effective dental care. This clinical study aims to evaluate the effectiveness of two magic tricks distraction techniques (magic rope…
- Trial name
- NCT07075458
- Testing
- Magic Rope Trick, Magic Thumb Sleeves, Tell-Show-Do (TSD)
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Constricted Maxillary Arch
Effect of Mini-screw Assisted Rapid Palatal Expansion on Midpalatal Suture in Post-pubertal Patients: a CBCT Study
a device is going to be placed in the palate to non-growing patients who are diagnosed to have a constricted maxillary arch and require an expansion of the maxillary arch in their treatment plan.
- Trial name
- EMARPEMSPP (NCT07075211)
- Testing
- MARPE (mini-screw assisted rapid palatal expansion)
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Pulpotomies Primary Teeth, Anxiety
Dental Game Impact on Kids' Pulpotomy Pain and Anxiety
The aim of this study is to evaluate the effect of a dental simulation game on reducing pain and anxiety during primary teeth pulpotomy.
- Conditions
- Pulpotomies Primary Teeth, Anxiety, Pain
- Trial name
- Electronic (NCT07072559)
- Testing
- dental simulation game, tell show do
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Acute Myeloid Leukemia
Repurposing Itraconazole as an Adjuvant Therapy in Treatment of Patients With Acute Myeloid Leukemia: Is it a Hopeful Avenue for Enhancing Treatment Options?
A prospective, randomized, controlled, parallel clinical trial will be conducted at Clinical Oncology and Nuclear Medicine Center at Mansoura University Hospital to assess the efficacy of Itraconazole as an adjuvant therapy in…
- Trial name
- NCT07069933
- Testing
- Standard care +itraconazole 200mg, Chemotherapy
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Breast Cancer
Melatonin in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy
Melatonin is an attractive candidate with anticancer activities previously reported in various preclinical and clinical studies.
- Trial name
- NCT07067307
- Testing
- melatonin
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
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