Clinical trials: sponsored by Mansoura University
Acne Vulgaris
Effect of New Topical Preparation for Treatment of Acne Vulgaris
The investigators propose a randomized, double-blind control trial study to evaluate the efficacy and safety of the optimized topical combination ME of the investigated drugs in the treatment of acne vulgaris containing DAP-FLU…
- Trial name
- NCT05899699
- Testing
- DAP-FLU ME, Adapalene .1% gel
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Enteral Nutrition
Enteral Nutrition Guidelines and Patients' Outcomes
Critically ill patients often exhibit a hypermetabolic state and increased energy requirements due to their critical illnesses. Those patients cannot meet their nutritional requirements through oral feeding.
- Trial name
- NCT05900323
- Testing
- enteral nutrition guidelines
- Volunteers
- 68 people
- Sponsor
- Mansoura University
Volume Overload
Inferior Vena Cava Diameter Dependent Colloid Challenge Versus Routine Crystalloid Strategy Transurethral Resection Prostate
Background: Intravenous fluid replacement during transurethral resection of the prostate is still unclear. Ultrasonography of the inferior vena cava (IVC) has been recently used to assess the volume status and predict fluid…
- Trial name
- NCT04131361
- Testing
- Ultrasound-guided Inferior vena cava diameter dependent colloid challenge versus routine crystalloid strategy Fluid replacement
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Mansoura University
Pediatric Kidney Disease
Shockwave Lithotripsy (SWL) Versus SWL and Oral Dissolution Therapy (ODT) For Paediatrics Radiolucent Renal Stone
To conduct a RCT comparing SWL versus combined ODT and SWL as non-invasive methods for management of paediatrics radiolucent renal stone.
- Trial name
- NCT05896345
- Testing
- SWL, SWL and ODT
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Mansoura University
Pain, Haemorriodectomy
The Effect of Botulinum Toxin Injection After Hemorrhoidectomy in Pain Control.
Hemorrhoids are a common disease in the general population. Its prevalence is estimated to be 5-36 % and more prevalent in western countries .
- Conditions
- Pain, Haemorriodectomy, Anal Sphincterotomy
- Trial name
- NCT05891314
- Testing
- Botox Injectable Product, Internal sphincterotomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Rectocele, Obstructive Defecation Syndrome
Functional and Sexual Outcomes After Laparoscopic Ventral Mesh Rectopexy for Complex Rectocele
The ideal surgical strategy for treating complex rectocele remains a topic for debate, with the transanal, transperineal, and transvaginal approach and the abdominal approach being at conflict with one another.
- Trial name
- NCT05894226
- Testing
- laparoscopic ventral mesh rectopexy
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Mansoura University
Cesarean Section Complications
IM Neostigmine for Accelerating Bladder Emptying After CS by Spinal Anesthesia
The aim of this study is to assess the efficacy of IM neostigmine (0.5 mg) for acceleration of bladder evacuation and prevention of postoperative urine retention following cesarean delivery carried out under spinal anesthesia
- Trial name
- NCT04364607
- Testing
- Neostigmine, NaCl 0.9%
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Pilonidal Sinus
A Single Center Experience in the Management of Pilonidal Disease
Sacrococcygeal pilonidal disease (PND) is a common entity affecting the skin and subcutaneous tissue of the upper portion of the natal cleft of the buttocks.
- Trial name
- NCT05892198
- Testing
- surgery
- Volunteers
- 101 people
- Sponsor
- Mansoura University
Regional Block
Quadratus Lumborum Block Type 2 Versus Posterior Transversus Abdominus Plane Block
This patient population are at risk of adverse effects secondary to inadequate pain management such as inadequate maternal bonding and late ambulation.
- Trial name
- quadratus (NCT04773730)
- Testing
- Posterior transversus abdominus plane block, Quadratus lumborum block type 2
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Laparoscopic Cholecystectomy
Venlafaxine for Postoperative Pain of Laparoscopic Cholecystectomy
Recent studies on the impact of perioperative venlafaxine for treatment of acute postoperative pain have yielded positive outcomes .
- Trial name
- NCT05884268
- Testing
- Venlafaxine
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Peripheral Neuropathy
Efficacy of Roflumilast in Prevention of Peripheral Neuropathy
There are several mechanisms concerning pathophysiology of paclitaxel induced peripheral neuropathy. One of the main mechanisms is induction of Schwann cell dedifferentiation by paclitaxel.
- Trial name
- NCT05884281
- Testing
- Roflumilast
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Class I Malocclusion
Compartive Evalution of the Efficiency of Maxillary Canine Retraction Using Power Chain Versus Burstone T-loop
evaluate and compare the efficiency between elastomeric chains and burston T-loop retractors in terms of rate of maxillary canine retraction and canine movements
- Trial name
- NCT05882526
- Testing
- BURSTONE T-LOOP
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Mansoura University
Immediate Implant
Immediate Implant With Different Filling Materials
36 patients, were included in this study. They were chosen from the Outpatient Clinic in the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University for replacement of non-restorable maxillary…
- Trial name
- NCT05878392
- Testing
- bone filling materials
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Behçet's Diseasecases
Calprotectin and Ischemia Modified Albumin Serum to Measure Disease Activity in Behçet's Disease
Behçet's Disease activity was evaluated using BD Current Activity Form (BDCAF). Serum calprotectin and IMA concentrations were compared among active BD cases, inactive BD cases and control subjects.
- Trial name
- NCT05868538
- Testing
- Serum calprotectin and IMA concentrations
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Bulk-fill Which is Special Type of Resin Composite, Bisphenol A-Glycidyl Methacrylate
Bulk-fill With Different Technique Three-year Clinical Performance
The current study will be intended to evaluate and compare three-year clinical performance of class II bulk-fill resin composite restorations placed with different techniques.
- Trial name
- NCT05861908
- Testing
- Filtek™ Bulk Fill restoration, Heated Filtek™ Bulk Fill restoration, G-aenial™ BULK Injectable restoration
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Atrophic Anterior Alveolar Ridge
L- Shape Symphyseal Autogenous Bone Block for Alveolar Ridge Augmentation in Anterior Maxilla and Mandible
the aim of this study was to assess both horizontal and vertical alveolar bone augmentation for sever atrophied anterior maxilla and mandible, using L- shape autogenous bone block harvested from the symphysis.
- Trial name
- NCT05844540
- Testing
- harvesting bone block, Recipient site preparation, implant insertion
- Where
- Egypt
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Implant Complication, Bone Loss
Vertical Versus Inclined Implant to Retain Locator Maxillary Overdenture
Objectives: evaluate the success rate, prosthetic maintenance , clinical and radiologic results of vertical implants with straight abutments versus inclined implants with angled abutments to retain locator maxillary overdentures.
- Trial name
- NCT05843331
- Testing
- implants
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Septic Shock, Sepsis
Decatecholaminisation of Septic Shock With Dexmedetomidine and In-hospital Mortality
The study aims to determine whether the infusion of DEX in septic shock can reduce in-hospital mortality, norepinephrine infusion, need and duration for mechanical ventilation, and acute kidney injury without significant adverse…
- Trial name
- DECATSepsis (NCT05283083)
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Bone Loss
Effect of Block-out Spacer to Pick up Locator Attachments to Retain Overdenture: Peri-implant and Alveolar Bone Changes
This study was conducted to radiographically evaluate peri-implant and alveolar bone height changes of locator attachments used for three implant assisted mandibular complete overdenture using two different pick up protocols.
- Trial name
- NCT05843825
- Testing
- Surgical placement of dental implants, Overdenture supported by locator attachment system
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Ridge Splitting
Effect of Laser Biostimulation With Mandibular Ridge Splitting and Peek Overdenture
This study was conducted to determine the effectiveness of two-implant retained polyetheretherketone (PEEK) overdentures on reducing the transmitted forces on implants placed with ridge splitting either treated with laser…
- Trial name
- NCT05837078
- Testing
- ridge splitting with implant placement
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mansoura University
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