Clinical trials: sponsored by Mansoura University
Pain Management, Hemodialysis
Virtual Reality Distraction During Arteriovenous Fistula Puncture
The cannulation of arteriovenous fistula is a painful procedure in hemodialysis patients. Previous studies have shown the effectiveness of virtual reality in reducing pain during needle-related procedures
- Conditions
- Pain Management, Hemodialysis, Virtual Reality
- Trial name
- NCT05399199
- Testing
- virtual reality distraction
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Mansoura University
Caudal Block
Methylprednisolone Versus Dexamethasone in Pediatric Caudal Block
This randomized, double-blind, controlled bi-center study was designed to compare the postoperative analgesic efficacy of dexamethasone and methylprednisolone in caudal block for children undergoing hypospadias surgical repair…
- Trial name
- NCT05717374
- Testing
- caudal block using dexamethasone, caudal block using methylprednisolone
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Tooth Extraction
Evaluation of β-tricalcium Phosphate/Calcium Sulfate Versus Allografts
Thirty healthy patients will be selected from the outpatient clinic of the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University, to be included in this study with non-restorable posterior…
- Trial name
- NCT05708196
- Testing
- Alloplast bone grafting material (EthOss, Ethoss Regeneration Ltd, Silsden, UK)., Allograft bone grafting material.
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Varicose Veins, Venous Reflux
Comparison of Zero- and Two-centimeter Distance From Sapheno-femoral Junction in Laser Ablation of Varicose Vein
EVLA is used in in treating refluxing veins, commonly the GSV. The tip of catheter is usually placed 2-2.5 cm distal to the sapheno-femoral junction.
- Conditions
- Varicose Veins, Venous Reflux, Venous Insufficiency, Venous Leg Ulcer
- Trial name
- NCT05707169
- Testing
- Saphenous Ablation, Endogenous Laser Ablation (EVLA), mixture of 20 mL 2% lidocaine, 1: 200,000 adrenaline and 20 mL 0.5% levobupivacaine in 1 L of 0.9% saline
- Where
- Egypt
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Anticoagulants; Increased
Efficacy of Direct Oral Anticoagulants as a Prophylactic Anticoagulation of Catheter Induced Thrombosis
Direct Oral Anticoagulants INTRODUCTION: DOAC's looks like an attractive alternative to VKA because they offer important advantages beyond their easiness of administration, like less interactions and no need of laboratory…
- Trial name
- NCT05705076
- Testing
- catheter induced thromboprophylaxis
- Volunteers
- 1,100 people
- Sponsor
- Mansoura University
Recurrent Caries
Clinical Performance of Three Universal Adhesives in Posterior Restorations
This study was designed to evaluate and compare the two-year clinical performance of three universal adhesives in posterior composite restorations, based on International dental federation (FDI) criteria.
- Trial name
- NCT05696431
- Testing
- Universal adhesives application, universal adhesive with bioactive properties, Fluoride-releasing universal adhesive
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Postoperative Pain
The Effect of Intraoperative Tramadol on Postoperative Opioid
Postoperative pain remains a very UNPLEASENTevent, particularly in morbidly obese patients that may be associated with obstructive sleep apnea.
- Trial name
- LSG (NCT05696886)
- Testing
- Pethidine, Tramadol with pethidine
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Mansoura University
Early Tooth Exfoliation
Different Designs of Space Maintainer
Purpose: Evaluation of survival rate for three space maintainers (SMs) of different designs versus standard one. Methods: 52 extraction sites in children of age group of 4-7 years with prematurely-lost 1st primary molar were…
- Trial name
- NCT05693870
- Testing
- Fixed space maintainer
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Mansoura University
Primary Teeth, Pulp Necroses
Treatment of Infected Pulp in Primary Teeth With a Mixture of Calcium Hydroxide and Gingerols
This study was conducted to evaluate Calcium Hydroxide mixed with Gingerols versus Metapex in treatment of primary teeth with infected necrotic pulp
- Conditions
- Primary Teeth, Pulp Necroses, Infected Pulp, Root Canal Treatment
- Trial name
- NCT05181813
- Testing
- Ginge-Cal, Metapex
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Diabetic Foot Ulcer
Bioactive Smart Dressings for Diabetic Foot Ulcers: Randomized Controlled Trial
We propose a randomized controlled study to assess the efficacy of: 1. Platelet-lysate loaded sustained release thermo-gelling formulation (Platelets-SR) 2.
- Trial name
- NCT05671250
- Testing
- PRP gel and SOC-treatment, EPO/ISDN/UFH cryogel dressing, Standard of Care
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Breast Cancer Stage IV
Cyclin Dependant Kinase 4/6 (CDK4/6) Inhibitors as a Second Line Treatment in Metastatic Breast Cancer Patients
Breast cancer is the commonest malignancy among females and one of the leading causes of death worldwide. Many drugs have been developed over the years to try to extend survival among these patients including cyclin dependant…
- Trial name
- NCT05670054
- Testing
- comparing both arms as regard the objective response rate, toxicity profile, quality of life, progression free survival
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Mansoura University
Acute Kidney Injury, Acute Renal Injury
Renal and Cardiac Risk Factors of AKI After Liver Transplantation
Background: Liver transplantation (LT) is an extensive operation with various factors contributing to the development of acute kidney injury in the perioperative period.
- Conditions
- Acute Kidney Injury, Acute Renal Injury, Liver Transplant; Complications
- Trial name
- NCT05666232
- Testing
- renal resistive index and myocardial performance index
- Volunteers
- 105 people
- Sponsor
- Mansoura University
Primary Open Angle Glaucoma
Visco-Circumferential-Suture-Trabeculotomy Versus Rigid Probe Viscotrabeculotomy in Primary Open Angle Glaucoma
Visco-Circumferential-Suture-Trabeculotomy versus Rigid probe Viscotrabeculotomy in Primary Open Angle Glaucoma.
- Trial name
- NCT05666440
- Testing
- Visco-Circumferential-Suture-Trabeculotomy in Primary Open Angle Glaucoma., Rigid probe Viscotrabeculotomy in Primary Open Angle Glaucoma.
- Volunteers
- 166 people
- Sponsor
- Mansoura University
Living Donor Liver Transplantation, Norepinephrine Bolus
Norepinephrine Boluses in Liver Transplantation
We study the efficacy of Norepinephrine boluses on prevention of postreperfusion syndrome during living donor liver transplantation.
- Conditions
- Living Donor Liver Transplantation, Norepinephrine Bolus, Postperfusion Syndrome
- Trial name
- NCT03773276
- Testing
- Norepinephrine boluses
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Post-COVID-19 Syndrome, Lung Fibrosis
Anti-Inflammatory and Anti-Fibrotic Drugs in Post COVID-19 Pulmonary Fibrosis
In this study we aim to evaluate the radiological and functional changes in post-acute covid-19 pulmonary fibrosis patients in relation to anti-inflammatory and/or antifibrotic drugs prescribed during and after covid-19 pneumonia.
- Trial name
- NCT05648734
- Testing
- Corticosteroids alone, Corticosteroids + Colchicine, Corticosteroids + Pirfenidone
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Mansoura University
Renal Stone, Urinary Stones
Uric Acid Based Renal Stones: Clinical, Metabolic and Genetic Characterization
Reporting prevalence of uric acid based renal stones among patients with nephrolithiasis admitted to Mansoura Urology and Nephrology center (MUNC). Furthermore, identification of monogenic and polygenic uric acid stone formers.
- Trial name
- NCT05634434
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Foot Reflexology
Effect of Foot Reflexology on Pain Associated With Mediastinal Chest Drain Removal
Cardiovascular diseases (CVDs) remain the leading cause of death worldwide and significantly affect patient quality of life and socioeconomic status.
- Trial name
- NCT05631522
- Testing
- foot reflexology
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Prostate Cancer Stage I, Bladder Outlet Obstruction
Transurethral Prostate Enucleation in Surveillance Protocol for Low Risk Prostate Cancer
We will compare oncological and functional outcomes of anatomical endoscopic enucleation of the prostate (AEEP) versus continued medical treatment in low-risk prostate cancer patients for whom an active surveillance protocol was…
- Trial name
- NCT05631080
- Testing
- Anatomical Endoscpic enucleation of the Prostate
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Anesthesia, Spinal, Cesarean Section
Changes in Cardiac Output During Cesarean Delivery Under Spinal Anesthesia
Cardiac output will be measured in healthy parturients undergoing cesarean delivery under spinal anesthesia
- Conditions
- Anesthesia, Spinal, Cesarean Section, Echocardiography, Cardiac Output
- Trial name
- NCT05269537
- Testing
- Transthoracic Echocardiography, Spinal Anesthesia, Intrathecal Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Stone, Kidney
Endoscopic Combined Intrarenal Surgery Versus Multi-Tract Percutaneous Nephrolithotomy for Complex Renal Stones:
The aim of this study is to compare outcomes of endoscopic combined intrarenal surgery (ECIRS) with the multi-tract percutaneous nephrolithotomy for management of complex renal stones.
- Trial name
- NCT05460559
- Testing
- Group A (p-PCNL) procedure, Group B (s-ECIRS) procedure
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
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