Clinical trials: sponsored by Mansoura University
Post Spinal Anesthesia Shivering
Intravenous Versus Perineural Dexmedetomidine as Adjuvant in Adductor Canal Block for Total Knee Arthroplasty
Shivering increases the cardiac and systemic energy expenditure, oxygen consumption and carbon dioxide production. Definitive prevention and treatment of shivering is necessary to decrease the related complications and increase…
- Trial name
- dexmed_ACB (NCT04266145)
- Testing
- intravenous dexmedetomidine, adductor canal block dexmedetomidine
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Mansoura University
Obstructive Sleep Apnea
BASET Scoring: A Novel Simple Biometric Score and Potential Tool for Diagnosis and Grading of Obstructive Sleep Apnea Syndrome (OSAS) Patients
this study aims to assess the validity of BASET scoring as a new potential tool for diagnosis and grading the severity of OSAS patients and as screening of the risk factors of OSAS.
- Trial name
- BASET (NCT05511974)
- Testing
- BASET score
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Mansoura University
Pain Cancer
Fluoroscopic Anterior Approach Versus Ultrasound Guided Superior Hypogastric Plexus Neurolysis in Cancer Pelvic Pain
Cancer related pelvic pain can be debilitating and difficult to treat. Superior hypogastric plexus neurolysis (SHPN) is considered to be an option for adequately relieving pain, with fewer side effects and improving the quality…
- Trial name
- NCT05299047
- Testing
- Group US-guided, Group fluoroscopy-guided
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Mansoura University
Benign Prostatic Hyperplasia, Overactive Bladder
Efficacy of Tadalafil/Solifenacin VS Tamsulosin/Solifenacin Combination Therapy for BPH/OAB
The investigators will compare the efficacy and safety of tadalafil/solifenacin combination therapy versus tamsulosin/solifenacin combination therapy for the treatment of BPH/OAB in a randomized controlled trial (RCT).
- Trial name
- NCT05494567
- Testing
- Tadalafil 5mg, Tamsulosin Hcl 0.4 mg, solifenacin 10 mg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Voiding Disorders
Mirabegron, Propevirine, Solifenacin for Treatment of Lower Urinary Tract Symptoms During Intravesical BCG Instillation
A randomized controlled study to compare the efficacy of mirabegron, solifenacin and propevirine for treatment of Lower urinary tract symptoms during intravesical BCG installation
- Trial name
- NCT05490082
- Testing
- Mirabegron, Propevirine, Solifenacin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Ischemic Heart Disease, Coronary Artery Bypass Graft
The Pneumatic Tourniquet Technique for Endoscopic Radial Artery Harvest; Does it Affect Patient Hemodynamics?
This study aims to investigate the effect of the pneumatic tourniquet technique on the patients' hemodynamics; heart rate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP).
- Trial name
- NCT05349773
- Testing
- Pneumatic tourniquet, endoscopic left radial artery harvesting
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Mansoura University
Fluid Therapy
Goal Directed and Liberal Fluid Therapy
The aim is to compare intraoperative goal directed fluid therapy (GDFT) versus liberal fluid therapy in patients undergoing elective colorectal surgery by using noninvasive electrical cardiometry.
- Trial name
- NCT05487222
- Testing
- ICON
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Dental Caries
Bioactive Composite Versus Resin-Modified Glass Ionomer Liners: 2-Year Clinical Trial
compare 2-year clinical performance of recent bioactive ionic resin composite to resin-modified glass ionomer liner in indirect dental pulp treatment.
- Trial name
- BIRCRMGILYCT (NCT05470959)
- Testing
- ACTIVA bioactive, Riva LC
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Vital Pulp Therapy
Diagnostic Biomarkers to Correlate Molecular Changes and Inflammatory Cascade in the Dental Pulp.
This study aimed to evaluate the molecular changes that occur within the pulp tissue during inflammation and its correlation with vital pulp therapy with its different treatment modalities (Direct pulp capping, Partial Pulpotomy…
- Trial name
- NCT05464797
- Testing
- Pulp therapy, Cytokines level in pulpal blood.
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Abdominal Aortic Aneurysm
Carbon Dioxide Guided Angiography in Endovascular Abdominal Aortic Aneurysm Repair
Endovascular aneurysm repair (EVAR) has lower short-term morbidity and mortality than open surgery. Intra-arterial contrast agents are an important component of successful EVAR as the tool of choice for preoperative evaluation of…
- Trial name
- NCT04444999
- Testing
- Carbon Dioxide Angiography
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Ischemia, Anticoagulants
Clopidogrel Aspirin Therapy (CAT) Versus Apixiban Aspirin Therapy (AAT) After Lower Limb Revascularization
the Aim of the work is to compare the effect of CAT (Clopidogrel aspirin therapy) and AAT (Apixiban aspirin therapy) after lower extremity revascularization.
- Trial name
- CVAALR (NCT04168398)
- Testing
- Combination drug
- Where
- Egypt
- Volunteers
- 1,536 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Appendiceal Cancer
Surgical Outcome and Predictors of Overall Survival of Stage I-III Appendiceal Adenocarcinoma
A few studies investigated the predictors of overall survival in appendiceal adenocarcinoma. A SEER database analysis of 1404 patients with appendiceal adenocarcinoma found that older age, T4 tumors, N1-2 stage, poorly…
- Trial name
- NCT05452382
- Testing
- Partial colecctomy, Hemicolectomy
- Where
- United States
- Volunteers
- 2,607 people
- Sponsor
- Mansoura University
Total Knee Arthroplasty
Single-injection Modified 4 in 1 Block as Postoperative Analgesia in Total Knee Arthroplasty
Patients suffer from moderate to severe pain after TKA. Patients are asked to begin functional exercise as early as possible after surgery, and that requires adequate control of postoperative pain.
- Trial name
- NCT05447871
- Testing
- Ultrasound guided single injection modified 4 in 1 block technique, Ultrasound guided adductor canal block technique, Bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Dental Caries
Comparison of Clinical and Radiographic Outcomes of SMART Technique vs ART in Primary Molars
This study conducted on thirty children aged 3-6 years old of both genders, have bilateral carious lower first primary molars. Pre-operative periapical x- ray were taken for both sides.
- Trial name
- NCT05438381
- Testing
- Atraumatic Restorative Technique (ART), SMART Technique
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Critical Lower Limb Ischemia
Trans-pedal Access for Endovascular Revascularization in Complex Infra-popliteal Lesions in Critically Ischemic Limb
Background: critical limb ischemia is one of the most challenging cases we face nowadays with high risk for amputation, retrograde trans-pedal angioplasty offers an alternative technique after failure of traditional ante-grade…
- Trial name
- NCT05436405
- Testing
- Trans-pedal access for endovascular revascularization in complex infra-popliteal lesions in critically ischemic limb
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Mansoura University
Abdominal Massage
Effect of Abdominal Massage on Gastrointestinal Outcomes Among Critically Ill Patients
This study aims to investigate the effect of abdominal massage on gastrointestinal outcomes among critically ill patients receiving enteral feeding.
- Trial name
- NCT05423054
- Testing
- Abdominal massage
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Alveolar Bone Grafting
Evaluation of Computer-Guided Secondary Alveolar Cleft Bone Grafting With and Without Platelet-Rich Fibrin
This study aims at investigating the role of platelet-rich fibrin in alveolar cleft secondary grafting. This grafting is done from the patient's chin using a computer-guided stent that is customized for each patient, and the…
- Trial name
- NCT05422196
- Testing
- Platelet-rich fibrin
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Gastroesophageal Reflux
Prevalence, Predictors and Management of Gastroesophageal Reflux After Laparoscopic Sleeve Gastrectomy
From January 2017 to January 2022, we looked at patients who had primary LSG and developed GERD. Before and after surgery, patients for LSG performed barium meal in Trendelenburg position and upper GIT endoscopy.
- Trial name
- LSG-GERD (NCT05416645)
- Testing
- patients with GERD after LSG
- Where
- Egypt
- Volunteers
- 1,537 people
- Sponsor
- Mansoura University
Preterm Infant, Body Composition
Effect of Tactile/Kinaesthetic Massage Therapy on DXA Parameter of Preterm Infants
The effect of Tactile/Kinaesthetic massage therapy on weight gain and different components of growth, as assessed by anthropometric measurements and DXA scan, and correlate these components with serum IGF-1, leptin and…
- Conditions
- Preterm Infant, Body Composition, Dual X-ray Absorptiometry (DXA) Scan
- Trial name
- NCT03412578
- Testing
- Massage Therapy
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University Children Hospital
Aromatherapy
Effect of Aromatherapy Massage on Sleep Quality of Post-operative Cardiothoracic Patients
Poor sleep is common in the ICU, especially among post-operative CABG and more severely ill patients. Additionally, patients after surgery suffer from changes in physiological parameters related to ICU stressors.
- Trial name
- NCT05408650
- Testing
- Aromatherapy Massage
- Volunteers
- 62 people
- Sponsor
- Mansoura University
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