Clinical trials: sponsored by Mansoura University
Missing Teeth
Effect of Topical Application of Hyaluronic Acid on Stability of Immediate Loading Dental Implant in Posterior Maxilla
Effect of Topical Application of Hyaluronic Acid on Stability of Immediate Loading Dental Implant in Posterior Maxilla
- Trial name
- NCT05403099
- Testing
- Hyaluronic acid, conventional implant placement
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Traumatic Brain Injury
Efficacy of Lung and Inferior Vena Cava Sonography for Fluid Optimization
Traumatic brain injury (TBI) is a leading cause of death and disability in trauma patients. As the primary injury cannot be reversed, management strategies must focus on preventing secondary injury by avoiding hypotension and…
- Trial name
- NCT05400343
- Testing
- Standard care (control group), US-guided fluid management (active group), Standard ICU Care
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
Childhood Asthma
Using Buteyko Breathing Technique to Control Asthma in School-Age Children
Asthma is a complex condition that can impair not only the child's physical growth but also his optimal functional capacity and performance.
- Trial name
- NCT05390554
- Testing
- Buteyko Breathing Technique
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Mansoura University
Fibromyalgia
Effect of Milnacipran / Gabapentin in Fibromyalgia
Gabapentin and milnacipran (MLN) show strong evidence of reduced pain, increased sleep, and improvement in the quality of life in fibromyalgia (FM) patients. Most FM trials focus primarily on pain reduction with monotherapy.
- Trial name
- NCT05384210
- Testing
- Milnacipran, Gabapentin, Combined gabapentin/milnacipran
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Mansoura University
Preterm Infant, Placental Insufficiency
Effect of Delayed Cord Clamping in Preterm Neonates With Placental Insufficiency
To investigate the effect of delayed cord clamping (DCC) on hematopoietic progenitor cells (HPCs), hematological parameters including haemoglobin concentration and hematocrit value in premature infants (34 weeks gestational age…
- Conditions
- Preterm Infant, Placental Insufficiency, Placental Transfusion
- Trial name
- NCT03731546
- Testing
- Delayed cord clamping
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University Children Hospital
Pain, Postoperative
Duloxetine for Postoperative Pain of Laparoscopic Cholecystectomy
Recent studies on the impact of perioperative duloxetine for treatment of acute postoperative pain have yielded positive outcomes with respect to reduction opioid consumption.
- Trial name
- NCT05115123
- Testing
- Duloxetine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Guillain-Barre Syndrome, Myasthenia Gravis
Diaphragm Thickness by Ultrasonography in Neurological Disorders
participants will be allocated into three groups, acute neuropathy (Guillain Barre Syndrome) group, neuromuscular junction disorder(myasthenia gravis ) group, and control group(people with neurological disorders not affecting the…
- Trial name
- NCT05324176
- Testing
- diaphragmatic ultrasound
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Disease Activity
14.0- 3.0- 3.0- η Protein With Rheumatoid Arthritis
Aim of work: to explore the potential association between serum 14.0-3.0-3.0- η protein level with disease activity and bone mineral density (BMD) in Egyptian patients with rheumatoid arthritis (RA).
- Trial name
- NCT05366608
- Testing
- Serum level of 14.0- 3.0- 3.0- η protein and IL_.6
- Where
- Egypt
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Bladder Cancer
Novel Urine-Based DNA Methylation Biomarkers for Urothelial Bladder Carcinoma Detection in Patients With Hematuria
The current study aimed to assess the diagnostic performance of novel urine-based DNA hypermethylation of six genes (GATA4, P16, P14, APC, CDH1 and CD99) for UBC detection in patients with hematuria.
- Trial name
- NCT05362539
- Testing
- Cystoscopy, Computed tomography, DNA hypermethylation assay
- Where
- Egypt
- Volunteers
- 246 people
- Sponsor
- Mansoura University
Placental Insufficiency, Preterm Infant
Impact of Umbilical Cord Milking in Preterm Neonates With Placental Insufficiency
To investigate the effect of umbilical cord milking (UCM) on peripheral hematologic parameters including hematopoietic progenitor cells in premature infants ≤ 34 weeks gestational age with placental insufficiency.
- Trial name
- NCT03731611
- Testing
- Umbilical Cord Milking
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University Children Hospital
Cirrhosis
Orphenadrine Versus Baclofen in Treatment of Muscle Cramps in Cirrhotic Patients
Muscle cramps are commonly affects patients with cirrhosis. It adversely influences the quality of life of cirrhotic patients. Treatment of muscle cramps still challenging owing to the diversity of the responsible…
- Trial name
- NCT04509336
- Testing
- Orphenadrine, Baclofen
- Where
- Egypt
- Volunteers
- 5 people
- Sponsor
- Mansoura University
Pain, Local Anesthetics
Effect of Different Approaches of Delivering Local Dental Anesthesia on Pain Perception in Children.
The aim of the study is to compare the efficacy of three different approaches of local anesthesia (LA) administration (Warm[37°C] LA, Buffered LA, and BUZZY device) on pain perception to young children ( 6-12 years old) using…
- Conditions
- Pain, Local Anesthetics, Epinephrine, Vibration
- Trial name
- NCT05338983
- Testing
- Topical anesthetic, Avent baby bottle warmer, Sodium bicarbonate
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Ventilator Associated Pneumonia
Implementing Oral Care Bundle on Critical Care Nurses' Practice and Mechanically Ventilated Patients' Outcomes
Oral care is a fundamental aspect of nursing that impact the health and comfort of patients over both the short and long term. Caring for very sick patients in a busy stressful environment may result in oral care having a lower…
- Trial name
- NCT05351619
- Testing
- oral care bundle implementation
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Mansoura University
Infected Pulp, Root Canal Treatment
Evaluation Of Different Pulpotomy Agents Used For Treatment Of Immature Molars
The management of permanent teeth with incomplete root development with compromised pulpal integrity presents a unique challenge.
- Trial name
- NCT05347160
- Testing
- Biodentine
- Where
- Egypt
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Bowel; Functional Syndrome, Rectal Cancer
Long Term Bowel Function Following Rectal Cancer Surgery
In this longitudinal study, 171 patients were evaluated and compared based on the radiation therapy they received. Bowel function was assessed longitudinally with Memorial Sloan Kettering Cancer Center and Wexner scores every 6…
- Trial name
- NCT05339763
- Testing
- chemoradiotherapy
- Where
- Egypt
- Volunteers
- 171 people
- Sponsor
- Mansoura University
Caries Arrest
Arresting Active Dentine Lesions and Quality of Life Among a Group of Preschool Children
Testing 3 different caries arresting techniques and the quality of life of a group of preschool children in Mansoura city, Egypt.
- Trial name
- NCT05314660
- Testing
- 38 % silver diamine fluoride, Atraumatic restorative technique, Ultra conservative dentistry
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Non-Muscle Invasive Bladder Cancer
Machine Learning-Based Prediction of BCG Response in High-Risk Non-Muscle Invasive Bladder Cancer Patients
This prospective study aims at using Artificial intelligence to create a helpful unbiased machine learning-based model that predicts BCG unresponsiveness in high risk BCG-naïve NMIBC patients incorporating all potential…
- Trial name
- NCT05332353
- Testing
- Bacillus Calmette-Guerin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Liver Transplantation, Ultrasonography, Doppler, Transcranial
Transcranial Doppler During Liver Transplantation
This is a prospective study that would investigate the transcranial doppler (TCD) changes during the living donor liver transplantation and the association between the TCD changes and the post-transplant neurological…
- Conditions
- Liver Transplantation, Ultrasonography, Doppler, Transcranial, Complication, Postoperative, Neurologic Deficits
- Trial name
- NCT05144451
- Testing
- Transcranial Doppler
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Postoperative Pain
Dexmedetomidine Versus Fentanyl for Sedation of Postoperative Mechanically Ventilated Neonates
Newborn infants experience pain after surgical procedures,prevention and management of pain in neonates is important due to its deleterious consequences.
- Trial name
- NCT05324891
- Testing
- Dexmedetomidine, Fentanyl
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Liver Transplant; Complications
ONSD and Neurotoxicity in Liver Transplant
This is a diagnostic test accuracy study. The investigators measure optic nerve sheath diameter (ONSD) by ultrasound on the eye during living donor liver transplantation operation at 5 minutes after reperfusion to predict the…
- Trial name
- NCT03799770
- Testing
- Optic nerve sheath diameter by ultrasound at 5 minutes post-reperfucion
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
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