Clinical trials: sponsored by Mansoura University
Wilms Tumor, Relapse
The Use of Immunohistochemical Staining for the Prediction of Wilms Tumour Progression and Recurrence
Wilms' tumour staging and grading are used to give an idea about the prognosis. Advanced staging, diffuse anaplasia, predominant blastemal elements and lymph node invasion are indicators of poor prognosis.
- Conditions
- Wilms Tumor, Relapse, Death
- Trial name
- NCT04758455
- Testing
- P53, Ki67 and Cyclin A IHC.
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Mansoura University
Neonatal Sepsis
Role of Montelukast in Modulation of Response to Sepsis in Preterm Infants
The investigators will conduct this study to explore the role of Montelukast in treatment of neonatal sepsis and whether it has an effect on inflammatory markers, the duration of antibiotic use, or on the patients´ outcome.
- Trial name
- NCT04474327
- Testing
- Montelukast Sodium
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University Children Hospital
Down Syndrome
the Effect of Cerebrolysin on Physical and Mental Functions of Down Syndrome
Down syndrome is a genetic disorder that causes delay in both physical growth and mental development. It is the most frequently reported chromosomal abnormality and the most common genetic syndrome.
- Trial name
- NCT04751136
- Testing
- cerebrolysin
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mansoura University Children Hospital
Vascular Access Complication
Prosthetic Femoral Access for Haemodialysis
This study will compare the outcomes of tunneled femoral catheter and femoro-femoral arteriovenous graft as a bailout procedure for hemodialysis in chronic kidney disease patients with exhausted upper-extremity and chest-wall…
- Trial name
- NCT04746742
- Testing
- Tunneled Femoral Catheter (TFC) group, Femoro-femoral Arteriovenous graft (FF-AVG) group
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Mansoura University
Thoracic Sympathectomy
Analgesic Effect of Erector Spinae Versus Serratus Anterior Plane Block for Thoracoscopic Sympathectomy
Thoracic incisions are painful and associated with chronic post-surgical pain and inadequate analgesia is associated with poorer postoperative outcomes.
- Trial name
- NCT04486014
- Testing
- Erector spinae plane block, Serratus anterior plane block
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Feeding Intolerance in Preterm, Intestinal Permeability in Preterm
Influence of Bovine Lactoferrin on Feeding Intolerance and Intestinal Permeability in Preterm Neonates
Preterm infants are at increased risk of developing feeding intolerance due to functional immaturity of their gastrointestinal tract and may lead to discontinuation of enterak feeding.
- Trial name
- NCT04738058
- Testing
- Bovine Lactoferrin Supplement
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University Children Hospital
Pneumonia, Viral
Remdesivir in Adults With Covid-19: Mansoura University Hospital Experience
COVID-19 is a respiratory disease caused by a new coronavirus (SARS-CoV-2) and causes significant morbidity and mortality. This study is a retrospective trial to assess the efficacy of Remdesivir in adult patients diagnosed with…
- Trial name
- NCT04728880
- Testing
- Remdesivir
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Mansoura University
Bladder Cancer
Can We Predict of the Response of High Risk Non Muscle Invasive Bladder Cancer Patients to Intravesical Bacillus Calmette-Guerin? The Role of Immunological Markers
Intravesical BCG is the mainstay adjuvant management of high risk NMIBC. Adequacy of immune system stimulation is the determinant factor for patient response to BCG.
- Trial name
- NCT04723121
- Testing
- Urine ELISA for immunological markers (IL-2 and IL-10), Reverse transcriptase-quantitative polymerase chain reaction (RT-qPCR) analysis
- Where
- Egypt
- Volunteers
- 204 people
- Sponsor
- Mansoura University
Placenta Accreta
Risk Factors for Occurrence of Placenta Accrete Spectrum Following Primary Cesarean Delivery
This study will be conducted on a group of patients undergoing repeat elective caesarean delivery attending at Mansoura university hospital.
- Trial name
- NCT04264169
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Mansoura University Hospital
Hypotension After Spinal Anesthesia
Midodrine for Improving Hemodynamics After Spinal Anesthesia
Neuraxial blockade such as spinal anaesthesia can cause severe hypotension due to pharmacological sympathectomy resulting in potential deleterious consequences for the patient.
- Trial name
- NCT04396548
- Testing
- Midodrine Oral Product
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Covid19
Impact of Vitamin D Level and Supplement on SLE Patients During COVID-19 Pandemic
Aim of the work Impact of serum vit D level in SLE patients with COVID-19 disease on severity of infection, duration of COVID-19 disease course, fatigue development as a complication for both SLE and COVID-19 and assess impact of…
- Trial name
- NCT04709744
- Testing
- Vitamin D, ELISA
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Mansoura University
Primary Congenital Glaucoma
Surgery for Primary Congenital Glaucoma in Neonates
The current study aimed to compare between the long-term surgical outcomes of 3 surgical options (viscotrabeculotomy (VT), visco-circumferential-suture-trabeculotomy (VCST) or combined VT-Trabeculectomy with MMC (VT-Trab) in…
- Trial name
- NCT04709497
- Testing
- viscotrabeculotomy (VT), visco-circumferential-suture-trabeculotomy (VCST) ., combined VT-Trabeculectomy with MMC (VT-Trab).
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Hypertensive Patients
A Comparative Study of Glidescope Versus Macintosh Laryngoscope in Adult Hypertensive Patients
Hemodynamic response to laryngoscopy and tracheal intubation remain of utmost concern in anesthesia practice. Sympathetic stimulation and adverse physiologic events could be tolerated by healthy individuals, but they may be…
- Trial name
- NCT03316443
- Testing
- Glidescope, Macintosh
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Contrast-induced Nephropathy, Statin
Effects Of Combination Therapy Of Statin And Ascorbic Acid For Prevention Of Contrast-Induced Nephropathy
To evaluate the benefit for statin use in prevention of of CI-AKI after computed tomography urogram (CTU).
- Conditions
- Contrast-induced Nephropathy, Statin, Ascorbic Acid, AKI
- Trial name
- NCT03391830
- Testing
- Atorvastatin-Ascorbic acid
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Mansoura University
Breast Cancer
Efficacy of Statin Addition to Neoadjuvant Chemotherapy Protocols for Breast Cancer
Different modalities for breast cancer treatments have exhausting and distressing side effects and toxicities leading to decreased compliance.
- Trial name
- NCT04705909
- Testing
- Pitavastatin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Idiopathic Macular Hole
ILM Inverted Flap Size in Macular Hole
In the current study, the investigators described the results of a randomized, comparative clinical trial that was conducted to study the impact of the size of internal limiting membrane (ILM) inverted flap on rate and timing of…
- Trial name
- NCT04683276
- Testing
- pars plana vitrectomy with ILM inverted flap
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Mansoura University
Primary Congenital Glaucoma
Visco-Circumferential-Suture-Trabeculotomy Versus Trabeculotomy
comparing outcomes of Visco-Circumferential-Suture-Trabeculotomy in primary congenital glaucoma to trabeculotomy
- Trial name
- NCT04683289
- Testing
- trabeculotomy
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Mansoura University
Radical Cystectomy
The Stroke Volume Optimization of Goal Directed Fluid Therapy During Radical Cystectomy
Although fluid therapy is of paramount value in anesthetic practice, there is no guideline available for perioperative fluid management in major abdominal surgery.
- Trial name
- NCT03262480
- Testing
- stroke volume optimization
- Where
- Egypt
- Volunteers
- 172 people
- Sponsor
- Mansoura University
Dental Leakage
36-Months Clinical Evaluation of Preheated and Room Temperature Resin Composite
Summary The aim of this study was to evaluate the effect of preheating resin composite (RC) on clinical performance of class I restorations in a period of 3-years using a split-mouth double-blinded randomized design.
- Trial name
- NCT04679220
- Testing
- Preheating
- Where
- Egypt
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Non-Muscle Invasive Bladder Cancer
Low Energy Shock Wave Therapy and Non-Muscle Invasive Bladder Cancer
The investigators hypothesize that low energy shock wave therapy (LESW) might induce damage to the tumor tissues of non-muscle invasive bladder cancer (NMIBC), so they could be ablated and detached from the surface.
- Trial name
- NCT04644835
- Testing
- Low Energy Shock Wave Treatment
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
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