Clinical trials: sponsored by Mansoura University
Knee Arthroscopy
Intra-articular Versus Intravenous Dexmedetomidine in Arthroscopic Knee Surgeries Under Local Anesthesia
The present study will be carried to evaluate the efficacy of intra-articular 0.5 bupivacaine with intra-articular or intravenous alpha-2agonist; Dexmedetomidine; for intraoperative anesthesia and postoperative analgesia after…
- Trial name
- NCT02730845
- Testing
- Intra-articular dexmedetomidine, Intravenous dexmedetomidine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Chronic Knee Joint Osteoarthritis
Saphenous Nerve Block Versus Platelet Rich Plasma for Chronic Knee Osteoarthritis
Knee osteoarthritis, as a progressive disease is one of the most common causes of pain, motor disorder and disability in the elderly.
- Trial name
- NCT03326544
- Testing
- Saphenous nerve block group, Platelet rich plasma group
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Mansoura University
Chronic Lower Limb Ischemia
Fascia Iliaca Block for Anesthesia in Lower Limb Thromboembolectomy
The fascia iliaca block (FIB) is an anterior approach to block the lumbar plexus. It disturbed mainly to the anterior region of the thigh by blocking the femoral nerve (LFC) and the lateral femoral cutaneous nerve.
- Trial name
- NCT03798834
- Testing
- Fascia iliaca block (FIB), Spinal anesthesia
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Mansoura University
Cancer Larynx, Total Laryngectomy
Effects of Propofol-dexmedetomidine on Immune Function in Patients With Cancer Larynx
The aim of this prospective, randomized clinical study is to compare between propofol and isoflurane on perioperative immune cell populations and function in patients undergoing total laryngectomy surgery.
- Trial name
- NCT02739958
- Testing
- Propofol group, Isoflurane group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Thyroid Surgery
The Efficacy of Intermediate Cervical Plexus Block Versus Cutaneous and Thyroid Capsular Blocks
Thyroid gland surgery is one of the most commonly performed operations for either benign or malignant pathologies Pain related to thyroid surgery is of moderate intensity .which may be treated with NSAIDs or opioids.
- Trial name
- NCT03269890
- Testing
- Capsule and cutaneous blocks, US-intermediate cervical plexus block
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Mansoura University
Fracture of Proximal Femur
Effect of Dexmedetomidine and Bupivacaine for Paravertebral Block
Fracture femur is a common that results in severe pain. Many methods of regional and peripheral analgesia have been described to treat such pain.
- Trial name
- NCT02801188
- Testing
- Bupivacaine, Mixture of bupivacaine and dexmedetomidine
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Mansoura University
Spine Surgery
Pregabalin Effects on Hypotensive Anesthesia During Spine Surgery.
Elective lumbar spine surgical procedures are commonly performed under controlled hypotension during general anesthesia. That is beneficial to limit the intraoperative blood loss and transfusions and improves surgical field.
- Trial name
- NCT03301025
- Testing
- Pregabalin
- Where
- 2 sites in Egypt
- Volunteers
- 106 people
- Sponsor
- Mansoura University
Hemodynamic Instability
Subclavian Versus Inferior Vena Cava Collapsibility Indices.
Traditional methods for intravascular volume status assessment include physical examination, raised leg test, central venous pressure (CVP) and pulmonary artery catheters occlusion pressure (PAWP).
- Trial name
- NCT03337386
- Testing
- inferior vena cava collapsibility, subclavian vein collapsibility, central venous pressure
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Mansoura University
Patient Compliance
Propofol Spinal Procedural Sedation for Cesarean Section
Patient's safety and satisfaction are major concerns of anesthesiologists and obstetricians. According to evidence, guidelines and quality markers, regional anesthesia is preferred over general anesthesia in obstetric surgery.
- Trial name
- NCT03437980
- Testing
- propofol
- Where
- 3 sites in Egypt
- Volunteers
- 228 people
- Sponsor
- Mansoura University
Supportive Care
Superficial Cervical Plexus Versus Retrolaminar Block in Parotid Surgeries
The parotid gland receives sensory and autonomic innervation. Sensory innervation is supplied by the auriculotemporal nerve (gland) and the great auricular nerve (fascia).
- Trial name
- NCT04138147
- Testing
- Superficial cervical plexus with auriculotemporal nerve blocks, Cervical retrolaminar with auriculotemporal nerve blocks
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Mansoura University
Bladder Cancer
Laser En Bloc Resection Of Bladder Tumor (HoLERBT) VS. Conventional Transurethral Resection Of Bladder Tumors (cTURBT)
Randomized clinical trial aiming to assess Holmium Laser En Bloc Resection Of Bladder Tumor (HoLERBT) in comparison with Conventional Transurethral Resection Of Bladder Tumors (cTURBT) in tumor histopathological staging quality…
- Trial name
- HoLERBT (NCT02555163)
- Testing
- HoLERBT, cTURBT
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Anesthesia
Comparative Study of Ultrasound Guided Combined Interscalene and Supraclavicular Brachial Plexus Block Versus General Anesthesia for Brachioaxillary Surgery in Renal Failure Patient
The aim of this study is to evaluate the efficacy of combined supraclavicular and interscalene brachial plexus block in brachio-axillary surgeries in chronic renal failure as a sole anesthetic technique in comparison to general…
- Trial name
- NCT04050891
- Testing
- combined supraclavicular and interscalene block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Upper Abdominal Surgery
Subcostal Transversus Abdominis Plane Versus Epidural Block in Abdominal Surgeries
The investegators aimed to compare the efficacy of subcostal Transversus abdominis plane analgesia, to epidural analgesia intra and postoperatively in upper abdominal surgeries.
- Trial name
- NCT03949452
- Testing
- Subcostal Transversus Abdominis Plane catheter, Epidural catheter
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Mansoura University
Breast Cancer, Radical Mastectomy Surgery
Efficacy of Tramadol With Levobupivacaine for Modified Pectoral Nerve Block
The aim of this study is to evaluate the addition of tramadol combined with levobupivacaine in the reduction of postoperative pain, postoperative opioid consumption after modified radical mastectomy surgery.
- Trial name
- NCT02625506
- Testing
- Levobupivacaine, Levobupivacaine and Tramadol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Tracheal Reconstruction
Dexmedetomidine for Bilateral Superficial Cervical Plexus Block for Reconstructive Tracheal Surgery
Tracheal resection and reconstruction (TRR) is the treatment of choice for most patients with tracheal stenosis or tracheal tumors .The post intubation tracheal stenosis is the common indication for (TRR).The immediate…
- Trial name
- NCT03426527
- Testing
- Levobupivacaine, Levobupivacaine-Dexmedetomidine, General Anaesthesia
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Upper Tracheal Resection, Tracheal Reconstruction Surgery
Local Wound Infiltration for Tracheal Reconstruction
Tracheal resection and reconstruction (TRR) is the treatment of choice for most patients with tracheal stenosis or tracheal tumors .The postintubation tracheal stenosis is the common indication for (TRR).The immediate…
- Trial name
- NCT02949661
- Testing
- Superficial cervical plexus block, Local wound infiltration
- Sponsor
- Mansoura University
Knee Arthroscopic Surgery
Analgesic Effect Of Intra-articular Bupivacaine Fentanyl for Postoperative Pain Relief in Knee Arthroscopic Surgery
However, local anesthetic agents can produce analgesia for a limited time when used as a single injection. Bupivacaine is a local anesthetic that has an immediate action on pain by blocking peripheral afferents.
- Trial name
- NCT03847792
- Testing
- Group DB/Dexamethasone-Bupivacaine, Group FB /Fentanyl-Bupivacaine
- Where
- 2 sites in Egypt
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Hematological Malignancy (Leukemia- Lymphoma)
Ketamine-ketorolac Versus Fentanyl- Ketorolac I.M in Children During Bone Marrow Biopsy
investigators aim to compare between anaesthetic regimens that included dual-agent (fentanyl and ketorolac) or (ketamine and ketorolac) analgesic therapy
- Trial name
- NCT03649334
- Testing
- ketamine-ketorolac, fentanyl- ketorolac
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Labor Pain, Full Term Pregnancy
Patient Controlled Remifentanil Analgesia for Normal Labour
Patient controlled remifentanil analgesia might offer comparative overall patient satisfaction and improved quality of analgesia after normal labour with continuous epidural analgesia.
- Trial name
- NCT04541719
- Testing
- Patient-controlled remifentanil analgesia, Epidural analgesia
- Where
- Egypt
- Sponsor
- Mansoura University
Elective Major Abdominal Surgery
Postoperative Analgesia of Quadratus Lumborum Block Versus Epidural Block After Major Abdominal Surgeries
Acute postoperative pain is an important issue after major abdominal surgeries for which different analgesic modalities have been tried.
- Trial name
- NCT04541732
- Testing
- Thoracic epidural block, Ultrasound-guided bilateral quadratus lumborum block, Induction of general anaesthesia with propofol
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
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