Clinical trials: sponsored by Mansoura University
Gastric Varix
EUS-guided Obturation of High Risk Gastric Varices Versus Standard Endoscopic Treatment
Gastric varices occur in patients with portal hypertension, mostly secondary to liver cirrhosis. Although they bleed less frequently than oesophageal varices, gastric variceal bleeding tends to be more severe with reported higher…
- Trial name
- NCT04222127
- Testing
- EUS guided injection of gastric varices by CYA, Direct endoscopic injection of gastric varices by CYA
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Mansoura University
Multiple Sclerosis
Correlation of Serum Lactate and Activity of Multiple Sclerosis
Correlation of serum lactate and activity of multiple sclerosis and its correlation to different type of MS
- Trial name
- NCT04210960
- Testing
- Magentic resonanace imaging, Magentic resonanace spectroscopy
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mansoura University Hospital
Pain, Chronic
Intraoperative Versus CT Guided Celiac Plexus Neurolysis in Unresectable Pancreatic Cancer
Many studies had stated that the coeliac plexus neurolysis (CPN) is a safe and effective treatment method of pain associated with pancreatic cancer.
- Trial name
- NCT03770247
- Testing
- Intraoperative celiac plexus neurolysis, CT guided celiac plexus neurolysis
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Mansoura University
Inguinal Hernia
Sutured Versus Cyanoacrylate Glue Mesh Fixation for Inguinal Hernia Repair
Because it avoids direct nerve irritation or entrapment, mesh fixation with tissue adhesive glue seems an optimal option to reduce postoperative pain.
- Trial name
- NCT04203940
- Testing
- Cyanoacryale, Suture
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Fibroid Uterus
Does Myomectomy for Intramural Fibroid Improve ART Outcome?
Intamural fibroids (myoma) do exist in some infertile women undergoing IVF treatment. There is controversy whether myomectomy before IVF treatment could improve IVF outcome.
- Trial name
- MIFART (NCT03796130)
- Testing
- Myomectomy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
EMBRYO IMPLANTATION
The Outcomes of ICSI Cycles With and Without Letrozole
A variety of genes working together with ovarian hormones conducts and precisely control the process of endometrial receptivity and implantation.
- Trial name
- NCT04159649
- Testing
- Letrozole 2.5Mg Tablet, Gonadotropins, endometrial sample in the pretreatment cycle
- Where
- Egypt
- Volunteers
- 224 people
- Sponsor
- Mansoura University
Bladder Cancer
Diagnostic Performance and Predictive Capacity of Immediate Urine Cytology After Transurethral Resection of Non-Muscle Invasive Bladder Cancer; A Prospective Study
The current study aimed at prospectively assessing the performance of IUC as a predictive tool for residual tumor after primary TURBT of NMIBC, and possible future recurrence.
- Trial name
- NCT04194112
- Testing
- immediate urine cytology
- Volunteers
- 198 people
- Sponsor
- Mansoura University
Ischemic Stroke, Cancer
Mechanism and Outcome of Acute Ischemic Stroke in Cancer Patients
Stroke is a part of circulatory diseases which are the primary cause of death in Egypt. It accounts 14% of all deaths thus ranks the 2nd after ischemic heart disease. Cancer accounts 9% of population mortality in Egypt.
- Trial name
- NCT04195048
- Testing
- Risk factors
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mansoura University Hospital
Intra Cerebral Hemorrhage, Hypertension
Proper Timing of Control of Hypertension and Outcome in Acute Spontaneous Intracerebral Hemorrhage.
The ideal management of blood pressure in BP after acute intracerebral haemorrhage is still debated and whether a higher intensive reduction of blood pressure after acute intracerebral haemorrhage may be better or not is still…
- Trial name
- NCT04167644
- Testing
- Modified Rankin Scale (mRS)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Mansoura University Hospital
OSA
Fractional Exhaled Nitric Oxide and CRP Levels in Egyptian Patients With Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea syndrome (OSAS) was associated with upper and lower respiratory tract inflammation, Fractional exhaled nitric oxide (FeNO) proposed as a marker of airway inflammation, few studies were done on the impact…
- Trial name
- NCT04179942
- Testing
- Fractional exhaled nitric oxide and CRP levels
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Bladder Cancer
Xpert Bladder Cancer Monitor; Prospective, Single, Tertiary-care Center Implementation Study
The primary objective of this prospective, single-centre study is to establish the clinical performance characteristics of Xpert Bladder Cancer Monitor on the GeneXpert Instrument Systems in comparison to the methods currently…
- Trial name
- NCT03715660
- Testing
- Xpert bladder cancer monitor
- Where
- Egypt
- Volunteers
- 198 people
- Sponsor
- Mansoura University
Ischemic Stroke, Carotid Stenosis
Extracranial Carotid & Intracranial Arterial Stenosis in Ischemic Stroke
The aim of the work is to; elucidate how the presence of carotid stenosis influence the pattern of stroke and also how it interact with other risk factors for stroke.
- Trial name
- NCT04162587
- Testing
- Carotid duplex+/- MRA neck, brain MRA+/-CT angio on carotid and brain, MRI brain
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mansoura University Hospital
Epilepsy, Drug Resistant
Drug Resistant Epilepsy: Clinical and Genetic Study
This study is to identify the clinical criteria of drug resistant epilepsy and to explore whether SCN1A c.3184 A/G (rs2298771) and ccl2(rs1024611) polymorphisms could serve as genetic based biomarkers to predict drug resistance…
- Trial name
- NCT04166305
- Testing
- Genetic study for SCN1A c.3184 A/G and CCL2-2518G>A polymorphism:
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Mansoura University Hospital
Guillain Barre Syndrome
Early Prediction of Respiratory and Autonomic Complications of GBS Using Neuromuscular Ultrasound
Neuromuscular US will be a good and non invasive predictor for respiratory and autonomic dysfunctions in GBS through evaluation of diaphragmatic thickness, phrenic and vagus nerve cross sectional area.
- Trial name
- NCT04166357
- Testing
- neuromuscular ultrasound
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University Hospital
Multiple Sclerosis
OCT and Early Cognitive Impairment in Multiple Sclerosis
The aim of this study is to investigate the relationship between cognitive impairment and retinal nerve fiber layer \& ganglion cell inner plexiform layer in MS.
- Trial name
- NCT04153773
- Testing
- OCT
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University Hospital
Urolithiasis, Stone;Renal
Mini- Percutaneous Nephrolithotomy Versus Standard Percutaneous Nephrolithotomy in the Treatment of Renal Stones.
The EUA Urolithiasis Guidelines Panel meta-analysis suggest that mPNL is at least as efficacious and safe as sPNL for the removal of renal calculi.
- Conditions
- Urolithiasis, Stone;Renal, Nephrolithiasis, PNL
- Trial name
- NCT04153461
- Testing
- MINI-PERCUTANEOUS NEPHROLITHOTOMY, STANDARD PERCUTANEOUS NEPHROLITHOTOMY
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Mansoura University
Multiple Sclerosis, Sexual Dysfunction
Sexual Dysfunction in Patients With Relapsing Remitting Multiple Sclerosis and Associated Comorbidities
This work aims to: 1. Investigate and correlate Sexual Dysfunction in relapsing-remitting Multiple Sclerosis patients with specific focus on 1. Specific neurologic deficit. 2. Depressive symptoms. 3. Comorbid factors. 4.
- Trial name
- NCT04157283
- Testing
- MRI brain, visual evoked potential, Cerebrospinal Fluid, Sexual dysfunction measure, Depressive symptoms assessment and Multiple Sclerosis Quality of Life-54(MSQOL-54)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University Hospital
Urolithiasis, Nephrolithotomy
Exit Strategy After Percutaneous Nephrolithotomy: Large or Small Bore Tube?
Regarding to the distribution of nephrostomy tube (NT) size usage by country. There was a clear distinction between countries that used solely the small bore (SB) NT (Chile and Australia) and those that used solely the large bore…
- Conditions
- Urolithiasis, Nephrolithotomy, Percutaneous Nephrolithotomy (PNL), Nephrostomy Tube (NT)
- Trial name
- NCT04153474
- Testing
- large-bore nephrostomy tube (LBNT), small-bore nephrostomy tube (SBNT)
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Mansoura University
Surgery to the Distal One Third of the Upper Limb
The Influence of Warm Bupivacaine on Supraclavicular Plexus Block Characteristics
Despite PH adjustment of local anesthetic solution improves the quality of the block in all respects with special advantage of early onset of sensory and motor block, adequate level of analgesia, and prolongation of duration of…
- Trial name
- NCT03265886
- Testing
- Warm bupivacaine at (37°c), Bupivacaine at operating room temperature (23°c)
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Bladder Cancer, Bladder Disease
The Potential Role Of MicroRNA-155 And Telomerase Reverse Transcriptase In Diagnosis Of Non-Muscle Invasive Bladder Cancer And Their Pathological Correlation
We try to assess the potential role of telomerase reverse transcriptase and MicroRNA (miR-155) in diagnosis of non-muscle-invasive bladder cancer and their correlation with stage and grade of the tumor.
- Conditions
- Bladder Cancer, Bladder Disease, Bladder Neoplasm, Micro-RNA
- Trial name
- NCT03591367
- Testing
- MicroRNAs-155, Human telomerase reverse transcriptase
- Where
- Egypt
- Volunteers
- 115 people
- Sponsor
- Mansoura University
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