Clinical trials: sponsored by Mansoura University
Rectal Prolapse
TEM Assisted Perineal Rectopexy in Treatment of Rectal Prolapse
Curvilinear incision in the postanal space, through the intersphincteric plane, insertion of Proctoscope of TEM technique and dissection till sacral promontory, insertion of mesh between the rectum and sacrum, post anal repair…
- Trial name
- NCT02609555
- Testing
- TEM perineal rectopexy
- Where
- Egypt
- Volunteers
- 7 people
- Sponsor
- Mansoura University
Anesthesia, Spinal, Cesarean Section
Combined Colloid Preload And Crystalloid Coload Versus Crystalloid Coload During Spinal Anesthesia for Cesarean Delivery
The study will compare one technique of fluid administration (combined colloid preload and crystalloid colaod) with another one (crystalloid coload) during elective cesarean delivery performed under spinal anesthesia.
- Trial name
- NCT02961842
- Testing
- 500 mL Colloid Preload, Spinal Anesthesia, Intrathecal Bupivacaine
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Mansoura University
Abdominoplasty Patients
Comparison of Three Techniques for Analgesia After Abdominoplasty
This study was conducted to demonstrate post-abdominoplasty analgesic duration consequent to three different surgically infiltrated LA techniques; bilateral TAPB, bilateral RSB and subcutaneous infiltration using the same volume…
- Trial name
- Maha1 (NCT03077581)
- Testing
- Transevrsus abdominus plane block, Rectus sheath block, local anesthesia infiltartion
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Mansoura University
Spine Surgeries
Thoracolumber Oterfacial Plane Block for Spine Surgery
The most commonly used technique to anesthetize patients scheduled for thoracic or lumbar spine surgery is general anesthesia. Analgesic techniques vary from the use of neuraxial techniques like epidural, intrathecal, or caudal…
- Trial name
- TLIP (NCT03060681)
- Testing
- Bupivacaine 0.5% injected in the thoraco-lumber inetrfacial plane block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Lower Limb Surgery
Optimal Single Dose Intrathecal Dexmedetomidine for Postoperative Analgesia
Spinal anesthesia is a commonly used technique for lower limb surgeries offering better quality of postoperative analgesia, lower incidence of side effects, and shorter post-anesthesia care unit stay than general anesthesia.
- Trial name
- NCT02660658
- Testing
- Intrathecal dexmedetomidine
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Mansoura University
Liver Transplanatation
Remote Ischemic Preconditioning in Liver Transplantation
Remote (upper arm) ischemic preconditioning in the donor of living donor liver transplanta to ameliorate the effect of reperfusion injury in recipients.
- Trial name
- RIRI (NCT02534025)
- Testing
- Ischemia preconditioining
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Blood Coagulation Tests ( INR, APTT)
Sugammadex Reversal of Neuromuscular Blockade and Postoperative Bleeding
Sugammadex is new drug that is used for reversal of rocuronium induced muscle relaxation. benefits of reversal of neuromuscular blockade appears to be of great value in living donor liver transplant recipients.
- Trial name
- Suga_bleeding (NCT02939430)
- Testing
- Sugammadex intravenous, Intravenous neostigmine and atropine
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Pregnancy, Severe Pre-eclampsia
Dexmedetomidine vs. Remifentanil for Pre-eclampsia During Caesarean Delivery
Preeclampsia is a pregnancy-specific, multisystem disorder that complicates approximately 5 % of pregnancies. Tracheal intubation in the women with severe pre-eclampsia is usually associated with exaggerated transient increases…
- Trial name
- NCT01766089
- Testing
- Remifentanil, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Rectal Prolapse
Pathologic Assessment of Rectal Prolapse in the Young
Patients aging less than 45 years with rectal prolapse will undergo full pathologic and functional assessment to determine the underlying etiology.
- Trial name
- NCT03012464
- Testing
- Pathologic and functional assessment
- Where
- 2 sites in Egypt
- Volunteers
- 10 people
- Sponsor
- Mansoura University
Postoperative; Parotitis
Gender and Opioid Consumption
Opioids are widely used for pain relief after major abdominal surgeries[1]. Sex differences in the opioid analgesia have been reported and investigated in human subjects and animal models In this study, effects of sex difference…
- Trial name
- GenderOpioid (NCT03006627)
- Testing
- postoperative morphine
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Internal Jugular Vein Cannulation
Sono-ease Device for Internal Jaguar Vein Cannulation
A novel device attached to ultrasound probe designed to increase success rate and safety of internal jugular vein cannulation.
- Trial name
- Sono-ease (NCT02973841)
- Testing
- Sono-ease device
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Internal Jugular Vein Cannulation
Insertion Angle and Needle Visualization During Ultrasound Guided Internal Jugular Vein Cannulation
Ultrasound guidance has been established as an effective and safe method during insertion of internal jugular vein catheter.. Needle visualization during advancement toward the vein has a great impact on both safety and success…
- Trial name
- US_angle (NCT02941094)
- Testing
- needle PLT-805AT, Ultrasound
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Mansoura University
Pleomorphic Adenoma of the Parotid Gland
Quadrant Versus Superficial Parotidectomy
The most common benign tumor of the parotid gland is the so called pleomorphic adenoma. Although benign, this tumor may recur after surgical removal due to tumor cells left behind during the surgical operation.
- Trial name
- NCT01607866
- Testing
- Quadrant parotidectomy, Superficial parotidectomy
- Where
- Egypt
- Sponsor
- Mansoura University
Quality of Life
Comparison of Antimicrobial Coated Ureteral Stents With Non-coated Stents
This study will be conducted to compare the efficacy of antimicrobial coated ureteral stent with non-coated stents in prevention of UTI in patients with ureteral stents
- Trial name
- NCT02266368
- Testing
- Antimicrobeal coated stents
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Ureteric Stones
Treatment of Upper Ureteric Stones
This study will be conducted to compare the success and complication rates of ureteroscopy, and shockwaves lithotripsy for treatment of upper ureteric stones ≤1 cm.
- Trial name
- NCT02469766
- Testing
- SWL, Semirigid URS, Flexible URS
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- Mansoura University
Massive Ascites
Impact Of Timing Of Drainage Of Massive Ascites On Operative And Post-Operative Course In Living-Donor Liver Transplant Recipients. A Prospective Randomized Controlled Trial.
Massive ascites is usually controlled over several weeks pre-operatively in liver transplant recipients with the risk of encephalopathy and peritonitis.
- Trial name
- AscitesLDLT (NCT02867293)
- Testing
- ultrasound guided ascitic fluid drainage, operative drainage of ascites through small skin incision after induction of anesthesia, ultrasound
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Modified Radical Mastectomy
Pecs II Block as Alternative for Paravertebral Block in Modified Radical Mastectomy
Breast surgeries are usually associated with significant postoperative pain. Suitability of analgesic technique after breast surgery is always questionable.
- Trial name
- NCT02839083
- Testing
- Thoracic Paravertebral group, Pecs II group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Laparoscopic Cholecystectomy
Spinal for Laparoscopic Cholecystectomy
In this study, the investigators will study spinal anesthesia for laparoscopic cholecystectomy in comparison to general anesthesia (GA) regarding patient satisfaction as a primary variable, intraoperative complications…
- Trial name
- Sp-Lap (NCT02768376)
- Testing
- Bupivacaine with Fentanyl (Spinal Anesthesia), General anesthesia
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Labial Alveolar Bone Thickness, Apical Root Resorption
Labial Alveolar Bone Thickness and Apical Root Resorption Changes Associated With Self-ligating Versus Conventional Brackets
Labial alveolar bone thickness and apical root resorption changes associated with self-ligating versus conventional brackets. The aim of this study will be to compare labial alveolar bone thickness and apical root resorption…
- Trial name
- NCT02816489
- Testing
- Clarity SL MBT brackets; 3M Unitek, Monrovia, CA, USA, Gemini MBT brackets; 3M Unitek, Monrovia, CA, USA
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Nasogasrtic Tube Insertion
Facilitation of NGT Insertion
Insertion of a nasogastric tube (NGT) in anesthetized patients can be a disappointing experience. Many techniques have been explained to improve success rate along with increasing safety, such as forward displacement of the…
- Trial name
- NGT (NCT02764632)
- Testing
- Digital facilitation
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Mansoura University