Clinical trials: sponsored by Marmara University
Lumbar Radiculopathy
Femoral Stretch Test in L2-L4 Lumbar Radiculopathy
This prospective observational study aims to evaluate the sensitivity of the femoral stretch test in patients with unilateral, single-root L2, L3, or L4 nerve root compression and to determine whether test positivity differs…
- Trial name
- NCT07799142
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Composite Resins, Clear Aligner Therapy
Surface Wear of Clear Aligner Attachment Composites
The aim of this study is to investigate the amount of surface wear that may occur during treatment with different composite materials used for clear aligner attachments.
- Trial name
- NCT07812220
- Testing
- GC Aligner Connect, VOCO AlignerFlow LC
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Marmara University
Pulmonary Embolism, Venous Thromboembolism
Prognostic Value of 2026 AHA/ACC Clinical Categorization in Acute Pulmonary Embolism Patients Presenting to the Emergency Department
Background: The 2026 American Heart Association/American College of Cardiology (AHA/ACC) Pulmonary Embolism Guideline (Creager et al., Circulation 2026) introduced a novel five-category (A-E) clinical classification system with…
- Conditions
- Pulmonary Embolism, Venous Thromboembolism, Acute Pulmonary Embolism
- Trial name
- APEX-2026 (NCT07805616)
- Testing
- 2026 AHA/ACC Clinical Risk Categorization
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Visual Impairments
Effects of Reformer Pilates and Vestibular Exercise Programs on Balance and Gait in Children With Visual Impairment
This study looks at whether Reformer Pilates can help children and adolescents with visual impairment improve their balance, walking patterns, and muscle strength. Participants are between 10 and 17 years old.
- Trial name
- NCT07789691
- Testing
- Equipment-Based Pilates Exercise (Reformer), Vestibular Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Marmara University
Dental Anxiety in Children
AI-Assisted Evaluation of Dental Anxiety in Children: A Machine Learning Approach
This observational study evaluated whether children's dental anxiety could be identified from their speech using artificial intelligence and machine learning methods.
- Trial name
- NCT07797777
- Testing
- Multimodal Speech-Based Dental Anxiety Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Marmara University
Hand Hygiene, School Health, Primary School Students, Health Education
Effect of Digital Method-Based Hand Hygiene Education on Handwashing Skills in Primary School Students
The aim of this study is to evaluate the effect of a digitally based hand hygiene education program developed for primary school students on their proper handwashing skills.
- Trial name
- DMHHE (NCT07799181)
- Testing
- Digital Hand Hygiene Education Program
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lumbosacral Radiculopathy, Neuropathic Pain From Lumbosacral Radiculopathy
TFESI and Neuropathic Pain in Lumbosacral Radiculopathy
Patients with lumbosacral radiculopathy frequently experience neuropathic pain due to nerve root compression. Transforaminal epidural steroid injection (TFESI) is commonly used for pain relief in these patients.
- Conditions
- Lumbosacral Radiculopathy, Neuropathic Pain From Lumbosacral Radiculopathy, Disc Herniation With Radiculopathy
- Trial name
- NCT07799155
- Testing
- Transforaminal Epidural Steroid Injections
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Marmara University
Low Back Pain (LBP), Lumbar Radiculopathy
The Effect of Needle Insertion Angle on Contrast Distribution and Treatment Outcomes in S1 Transforaminal Epidural Steroid Injections
Nerve compression due to lumbar disc herniation (lumbosacral radiculopathy) is a condition characterized by pain in the lower back and legs and restricted lumbar joint movement due to the compression of nerves emerging from the…
- Conditions
- Low Back Pain (LBP), Lumbar Radiculopathy, Intravascular Injection
- Trial name
- Transforaminal (NCT06801990)
- Testing
- S1 transforaminal epidural steroid(dexamethasone) injection
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Marmara University
Surgery, Rehabilitation
Postoperative Rehabilitation in Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity occurring in growing individuals. In cases with progressive curvature, posterior spinal fusion and instrumentation (PSF) is considered the…
- Conditions
- Surgery, Rehabilitation, Scoliosis; Adolescence
- Trial name
- NCT07791485
- Testing
- Exercise-Based Rehabilitation Program
- Volunteers
- 42 people
- Sponsor
- Marmara University
Tooth Discoloration Following Root Canal Treatment, Tooth Discoloration
Clinical Evaluation of Discoloration Induced by Root Canal Treatment in Vital and Devital Teeth
This prospective observational study aims to evaluate and compare tooth discoloration following root canal treatment in vital and devital teeth.
- Trial name
- NCT07781969
- Testing
- Root Canal Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Marmara University
Hemolysis, Blood Specimen Collection
Early vs. Late Tourniquet Release and Phlebotomy-Induced Hemolysis in the Emergency Department: TOURNI-ED
BACKGROUND: Hemolysis is the most common preanalytical error in emergency department (ED) laboratories, affecting 12-26% of blood samples collected in the ED and leading to test cancellations, repeat venipuncture, delayed…
- Conditions
- Hemolysis, Blood Specimen Collection, Phlebotomy, Venous Stasis
- Trial name
- TOURNI-ED (NCT07617103)
- Testing
- Sphygmomanometer-Applied Venous Stasis with Varied Release Timing During Phlebotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 792 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Overactive Bladder (OAB), Neuromodulation
Peroneal Neuromodulation vs Pelvic Floor Exercises in OAB
Overactive bladder (OAB) is a common condition characterized by urinary urgency, usually accompanied by increased urinary frequency and nocturia, with or without urgency urinary incontinence.
- Trial name
- NCT07788560
- Testing
- Transcutaneous Peroneal Electrical Neuromodulation, Pelvic Floor Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Psoriatic Arthritis, Enthesitis
Ultrasound and Shear Wave Elastography Assessment of Entheses in Psoriatic Arthritis
Psoriatic arthritis (PsA) is a chronic inflammatory disease that frequently involves the entheses, where tendons, ligaments, and fascia insert into bone.
- Trial name
- SWE-PsA (NCT07785089)
- Testing
- Grayscale Ultrasonography, Power Doppler Ultrasonography, and Shear Wave Elastography
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Knee Arthritis Osteoarthritis, Chronic Knee Pain
The Predictive Value of Ultrasonographic Quadriceps Muscle Parameters for Genicular Nerve Block Outcomes in Knee Osteoarthritis
The goal of this observational study is to learn whether thigh muscle structure can help predict pain relief after a genicular nerve block in people with knee osteoarthritis.
- Trial name
- NCT07781059
- Testing
- genicular nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Marmara University
Chronic Cervical Radicular Pain
Electrophysiological Predictors of Cervical DRG Pulsed Radiofrequency Outcomes
This observational study aims to determine whether electromyography and nerve conduction study findings can help predict the response to cervical dorsal root ganglion pulsed radiofrequency treatment in patients with chronic…
- Trial name
- NCT07776431
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Marmara University
Periodontitis
Boron Levels, Oxidative Stress, and Inflammation in Periodontitis
This cross-sectional observational study aims to evaluate the relationship between boron levels and oxidative stress, antioxidant defense, and inflammatory markers in individuals with periodontitis.
- Trial name
- NCT07775378
- Testing
- Biochemical Assessment of Saliva and Gingival Tissue
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Gingival Recessions
AI-Based Prediction of Root Coverage Outcome From Intraoral Photographs
This study evaluates whether the outcome of root coverage surgery can be predicted from a preoperative intraoral photograph. Adults with Cairo RT1,RT2 or RT3 gingival recessions treated with a coronally advanced flap and a…
- Trial name
- NCT07775365
- Testing
- Coronally advanced flap with subepithelial connective tissue graft, Deep learning based prediction of root coverage outcome
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Marmara University
Infant Sleep Safety
Animation-Supported Infant Sleep Safety Education
The aim of this research is to evaluate the effect of animation-supported sleep safety training on the knowledge and attitudes of pediatric nurses.
- Trial name
- NCT07771348
- Testing
- Animation-Supported Infant Sleep Safety Education
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lumbosacral Radicular Pain, Lumbar Radiculopathy
Determination of Sensitivity and Specificity of Straight Leg Raise Test Via Transforaminal Nerve Root Block
This study aims to evaluate the diagnostic accuracy of the straight leg raise test in patients with suspected lumbosacral radicular pain.
- Conditions
- Lumbosacral Radicular Pain, Lumbar Radiculopathy, Straight Leg Raise
- Trial name
- NCT07696312
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Marmara University
Hyaluronic Acid, Periodontal Therapy
Hyaluronic Acid as an Adjunct to Non-Surgical Periodontal Therapy in Smokers
The goal of this clinical trial is to evaluate whether hyaluronic acid (HA) improves periodontal healing in people with periodontal disease who smoke.
- Conditions
- Hyaluronic Acid, Periodontal Therapy, Oral Microbiota, Oxidative Stress
- Trial name
- NCT07597213
- Testing
- Scaling and Root Planing, Hyaluronic Acid (HYADENT BG)
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Marmara University