Clinical trials: open to volunteers, sponsored by Marmara University
Stroke
The Effects of an Augmented Reality-Based Mirror Therapy System in Patients With Stroke
Objective The aim of this study is to investigate the effects of an augmented reality-based mirror therapy system (MirrARm), developed using sensor-based tracking and visual feedback principles, on upper extremity motor recovery…
- Trial name
- NCT07533734
- Testing
- Augmented Reality-Based Mirror Therapy, Conventional Mirror Therapy, Conventional Physiotherapy Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Marmara University
Prematurity, Feeding Behaviors
Effects of Environmental Comfort and Oral Motor Stimulation on Comfort and Oral Feeding Readiness in Preterm Infants
This study aims to evaluate the effects of short-term environmental comfort interventions and oral motor stimulation on comfort and oral feeding readiness in preterm infants.
- Trial name
- NCT07917871
- Testing
- Massage, White Noise, Oral Motor Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Marmara University
Preterm Infants
Eye Covering and White Noise During Nasogastric Tube Insertion in Preterm Infants
This study aims to evaluate the effects of eye covering and white noise during nasogastric tube insertion on comfort, pain, stress, and physiological parameters in preterm infants.
- Trial name
- NCT07915154
- Testing
- Eye Covering, White Noise, Eye Covering and White Noise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Marmara University
Intubation, Endotracheal Tube Cuff Pressure
Effect of a Brief Educational Intervention on Endotracheal Tube Cuff Pressure
Endotracheal tube cuff pressure outside the recommended range of 20-30 cmH₂O is common in routine anesthesia practice. Over-inflation can injure the tracheal mucosa, while under-inflation increases the risk of aspiration and…
- Conditions
- Intubation, Endotracheal Tube Cuff Pressure, Anesthesia, Anesthesia,General
- Trial name
- NCT07891195
- Testing
- Brief educational intervention (educational video and reminder posters)
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Differentiated Thyroid Cancer (DTC), Papillary Thyroid Carcinoma
Serum Treg/Th17-Related Cytokines and Systemic Inflammatory Indices in Differentiated Thyroid Cancer
This study measures circulating immune-signaling molecules before thyroid surgery to determine whether they differ between patients whose thyroid nodule proves to be a differentiated thyroid carcinoma and patients whose nodule…
- Conditions
- Differentiated Thyroid Cancer (DTC), Papillary Thyroid Carcinoma, Thyroid Cancer, Thyroid Nodule
- Trial name
- THINC (NCT07907432)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Marmara University
Thyroid Diseases, Recurrent Laryngeal Nerve Injury
Endotracheal Tube Versus Transcartilage Needle Electrodes for Nerve Monitoring in Thyroid Surgery
Intraoperative neuromonitoring of the recurrent laryngeal nerve during thyroidectomy is most commonly performed with surface electrodes embedded in the endotracheal tube (ETT).
- Conditions
- Thyroid Diseases, Recurrent Laryngeal Nerve Injury, Vocal Cord Paralysis, Thyroid Nodule
- Trial name
- TRANSCOMP (NCT07902349)
- Testing
- Transcartilage needle electrode recording, Endotracheal tube surface electrode recording
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Ceserean Section, Obstetric Quality of Recovery
Anesthetic Technique and Quality of Recovery After Cesarean Delivery
The goal of this prospective observational study is to evaluate whether the type of neuraxial anesthesia is associated with postoperative quality of recovery in adult women undergoing cesarean delivery.
- Conditions
- Ceserean Section, Obstetric Quality of Recovery, Neuraxial Anesthesia
- Trial name
- NCT07896733
- Testing
- Spinal anesthesia (heavy bupivacaine), epidural anesthesia, combine spinal epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Marmara University
Inguinal Hernia Unilateral, Postoperative Pain
Quadro-Iliac Plane Block for Postoperative Analgesia in Laparoscopic Inguinal Hernia Repair
The goal of this randomized controlled trial is to learn whether an ultrasound-guided quadro-iliac plane block (QIPB) reduces opioid use and pain after laparoscopic inguinal hernia repair in adults aged 18-65 years.
- Conditions
- Inguinal Hernia Unilateral, Postoperative Pain, Opioid Use
- Trial name
- QIPB-LIHR (NCT07878936)
- Testing
- Quadro-iliac plane block
- Volunteers
- 64 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Lumbar Radicular Pain, Artifical Intelligence
MRI-Based Artificial Intelligence Prediction of Fluoroscopic C-Arm Angles for Lumbar Transforaminal Epidural Steroid Injections
This study aims to prospectively evaluate the accuracy of artificial intelligence (AI) in predicting fluoroscopic C-arm oblique and craniocaudal angles from pre-procedural lumbar magnetic resonance (MR) images for lumbar…
- Trial name
- NCT07875855
- Testing
- AI based evaluation
- Volunteers
- 80 people
- Sponsor
- Marmara University
Parkinson Disease
Comparison of Vestibular and Dual-Task Rehabilitation in Parkinson's Disease
Parkinson's disease (PD) is a long-term condition that affects movement, balance, and thinking abilities. It can cause tremor, stiffness, slow movements, and difficulty maintaining balance.
- Trial name
- NCT07277205
- Testing
- Vestibular Rehabilitation, Cognitive-Motor Dual Task Activities
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Marmara University
Type 1 Diabetes, Children
Think-Find-Solve Activities for Insulin Self-Management in Type 1 Diabetes
Children with type 1 diabetes require lifelong insulin therapy. However, improper management of insulin therapy may lead to serious, potentially life-threatening complications.
- Conditions
- Type 1 Diabetes, Children, Activity, Insulin
- Trial name
- NCT07670572
- Testing
- Insulin Self-Management Know-Find-Solve Activity Book, Routine education
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Marmara University
Healthy Participants
Physiological and Neurocognitive Responses to Multisensory Food Cues in VR
This study aims to investigate how food cravings change when visual food cues are enriched with sound, smell, and interactive experiences in a virtual reality (VR) environment.
- Trial name
- NCT07320209
- Testing
- Real food, Virtual Reality Food
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Marmara University
Spinal Stenosis Lumbar, Neuropathic Pain
Neuropathic Pain Severity and Its Association With Radiological Findings in Lumbar Spinal Stenosis
This cross-sectional observational study aims to evaluate neuropathic pain severity in patients with lumbar spinal stenosis (LSS) and to investigate its association with radiological findings.
- Trial name
- NCT07855445
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Spinal Stenosis Lumbar, Sarcopenia
Sarcopenia and Interlaminar Epidural Steroid Injection Outcomes in Lumbar Spinal Stenosis
This prospective observational study aims to investigate the association between sarcopenia and clinical outcomes following interlaminar epidural steroid injection in patients with lumbar spinal stenosis.
- Trial name
- NCT07855419
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Marmara University
Chronic Low Back Pain, Lumbar Facet Joint Degeneration
Association of Subcutaneous Fat Index, Paraspinal Muscle Characteristics, and Facet Morphology With Lumbar Facet Joint Degeneration
This prospective observational study aims to investigate the association between subcutaneous fat index, paraspinal muscle characteristics, facet morphology, and lumbar facet joint degeneration in adults with chronic low back…
- Trial name
- NCT07860697
- Testing
- Lumbar Magnetic Resonance Imaging (MRI)
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Marmara University
Hemolysis, Diagnostic Errors
Pneumatic Tube System Versus Personnel Transport and the Hemolysis Index of Emergency Department Blood Samples: A Randomized, Split-Sample, Single-Blind Trial
Hemolysis is the most common pre-analytical error in emergency department (ED) laboratory specimens and can lead to false elevation of intracellular analytes (potassium, LDH, AST, hemoglobin), resulting in misdiagnosis and…
- Conditions
- Hemolysis, Diagnostic Errors, Blood Specimen Collection
- Trial name
- PTS-HEMO-ED (NCT07755007)
- Testing
- Pneumatic Tube System Transport, Manual Personnel Transport
- Where
- Turkey (Türkiye)
- Volunteers
- 166 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Premature Loss of Primary Molars
Chewing Pattern Changes Before and After Space Maintainer Placement in Children
This prospective observational study aims to evaluate changes in chewing patterns and chewing performance in children before and after placement of a unilateral fixed band-and-loop space maintainer.
- Trial name
- NCT07828158
- Testing
- Band-and-Loop Space Maintainer
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Marmara University
Coccydynia, Chronic Pain
Alexithymia, Pain Intensity, Quality of Life, and Psychological Symptoms in Chronic Coccydynia Patients Scheduled for Ganglion Impar Block
Chronic coccydynia is characterized by pain localized to the coccygeal region that typically worsens with sitting, leading to notable impairments in functional performance and health-related quality of life.
- Conditions
- Coccydynia, Chronic Pain, Alexithymia
- Trial name
- NCT07828145
- Testing
- Psychometric and Clinical Survey Battery
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Marmara University
Chronic Low Back Pain, Radiculopathy
Effect of Alexithymia on Treatment Response to Transforaminal Epidural Steroid Injections in Chronic Low Back Pain
Low back pain and lumbosakral radiculopathy represent common clinical challenges substantially diminishing health-related quality of life and work productivity.
- Conditions
- Chronic Low Back Pain, Radiculopathy, Alexithymia
- Trial name
- NCT07828132
- Testing
- Psychometric Assessment and Clinical Follow-up Battery
- Volunteers
- 60 people
- Sponsor
- Marmara University
Lumbar Radiculopathy
Femoral Stretch Test in L2-L4 Lumbar Radiculopathy
This prospective observational study aims to evaluate the sensitivity of the femoral stretch test in patients with unilateral, single-root L2, L3, or L4 nerve root compression and to determine whether test positivity differs…
- Trial name
- NCT07799142
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University