Clinical trials: sponsored by Meyer Children's Hospital IRCCS
Fractures, Bone
Investigation of a Medical Device for the Immobilisation of Radius and Ulna Fractures in Paediatric Patients
Single-centre, randomised, controlled, non-profit study on a custom-made medical device for immobilisation of radius and ulna fracture in paediatric patients.
- Trial name
- T3DDY02 (NCT06312995)
- Testing
- T3DDY01, PLASTER
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Meyer Children's Hospital IRCCS
Oncologic Disease, Hematologic Diseases
Molecular Characterizazion and Biological Samples Centralisation of Patients Affected by Oncoematolofic Pathology
Currently, the molecular characterization of onco-hematological, onco-immunological and hematological diseases, at onset or in relapse, of patients with suspected diagnosis afferent to the CROP centers, is done through…
- Trial name
- NCT06304194
- Testing
- Analysis of biological samples
- Where
- 3 sites in Italy
- Volunteers
- 340 people
- Sponsor
- Meyer Children's Hospital IRCCS
Atresia Esophagus
A Study of Patients Undergoing Surgical Treatment for Oesophageal Atresia
Oesophageal atresia (EA) is a rare congenital anomaly whose prevalence varies between 1 and 2 per 5000 live births in Europe. This condition is characterised by an interruption of the oesophagus often associated with the presence…
- Trial name
- NCT06286826
- Testing
- Postero-lateral thoracotomy, Minithoracotomy
- Where
- 3 sites in Italy
- Volunteers
- 50 people
- Sponsor
- Meyer Children's Hospital IRCCS
Acute Intoxication
Multicentre Prospective Observational Study of Acute Intoxications in Paediatric Age
Acute intoxications represent a major public health problem, especially when affect a population such as children, who are vulnerable and at greater risk of unintentional and preventable poisonings.
- Trial name
- NCT06291649
- Where
- 31 sites in Italy
- Volunteers
- 90 people
- Sponsor
- Meyer Children's Hospital IRCCS
Tuberculosis Infection
Multicenter Italian Cohort Study on Tuberculosis in Pediatric Age
According to the WHO report of 2021, approximately 10 million new cases were reported in 2020, of which 1 million occurred in the pediatric population.
- Trial name
- NCT06289660
- Where
- 17 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Meyer Children's Hospital IRCCS
Feeding and Eating Disorders of Childhood
Italian Language Validation of The Eating Disorder Examination (EDE) - Child Version
Although eating disorders often occur during or after puberty, it is likely that critical antecedent conditions can be established before adolescence.
- Trial name
- NCT06286852
- Testing
- Administration of K-SADS-PL- Kiddie-Schedule for Affective Disorder and Schizophrenia-Present and Lifetime version (Kaufmann, 2002), Administration of ChEDE- Child Version of the EatingDisorder Examination
- Where
- 3 sites in Italy
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Meyer Children's Hospital IRCCS
Epilepsy, Genetic Disease
Transcranial Magnetic Stimulation (TMS) in Genetic Epilepsies
Transcranial magnetic stimulation (TMS) uses electromagnetic induction as an efficient, painless, non-invasive method to generate a suprathreshold current at the level of the encephalon, and provide in vivo measurements of…
- Trial name
- NCT06284291
- Testing
- transcranial magnetic stimulation (TMS)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Meyer Children's Hospital IRCCS
Eosinophilic Granulomatosis With Polyangiitis
The Epigenomic Signature of Eosinophilic Granulomatosis With Polyangiitis
This is a case-control observational study on blood samples. The primary goal of this study is to identify the epigenetic marks that can distinguish patients suffering from Eosinophilic Granulomatosis with Polyangiitis (EGPA)…
- Trial name
- EPI-EGPA (NCT06231498)
- Volunteers
- 300 people
- Sponsor
- Meyer Children's Hospital IRCCS
Premature Birth
Children Born Preterm: Sustainable Health Monitoring
Children born preterm are recognized to be at higher risk of short and long term complications and a formal follow-up of infants and children born preterm is recommended by international and national scientific societies.
- Trial name
- NCT06270368
- Where
- 4 sites in Italy
- Volunteers
- 650 people
- Sponsor
- Meyer Children's Hospital IRCCS
Covid19, Coronavirus Infection
Steam Inhalations in COVID-19 Patients
The new coronavirus (SARS-CoV-2) causing COVID-19 is an RNA virus coated with a capsid and a peri-capsid crossed by glycoprotein structures.
- Conditions
- Covid19, Coronavirus Infection, Coronavirus
- Trial name
- Steam-COVID (NCT04743349)
- Testing
- Steam inhalations
- Where
- Italy
- Volunteers
- 143 people
- Sponsor
- Meyer Children's Hospital IRCCS
Glioblastoma (GBM), DIPG
Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma
The standard therapy of glioblastoma (GBM) consists of gross total resection followed by focal irradiation to the tumor bed with concomitant and adjuvant temozolomide (TMZ).
- Conditions
- Glioblastoma (GBM), DIPG, Brainstem Glioma, Pediatric, Diffuse Spinal Glioma
- Trial name
- NCT02758366
- Testing
- Doxorubicin
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- Meyer Children's Hospital IRCCS
Status Epilepticus
Ketamine in Refractory Convulsive Status Epilepticus
To evaluate the efficacy of intravenous administration of ketamine in the treatment of refractory convulsive status epilepticus in children compared to administration of midazolam at high doses, thiopental and / or propofol.
- Trial name
- KETASER01 (NCT02431663)
- Testing
- Ketamine
- Where
- Italy
- Volunteers
- 57 people
- Sponsor
- Meyer Children's Hospital IRCCS
Venipuncture
Support Activities for the Reduction of Distress and Pain in Children During Venipuncture
To evaluate the efficacy of Health Support Activities (Animal Assisted Intervention, Clows, Musicians) in the reduction of pain and distress in children undergoing venipuncture.
- Trial name
- NCT03899766
- Testing
- Animal Assisted Intervention, Clowns, Musicians
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Meyer Children's Hospital IRCCS
Retinopathy of Prematurity
Safety and Efficacy of Propranolol 0.2% Eye Drops in Treating Retinopathy of Premature: A Pilot Study (DROP-ROP-0.2%)
The aim of the present study is to evaluate the safety and efficacy of propranolol 0.2% eye drops in treating preterm newborns with a precocious stage of retinopathy of prematurity (ROP).
- Trial name
- NCT02504944
- Testing
- Propranolol 0.2% eye drops
- Where
- 7 sites in Italy
- Volunteers
- 98 people
- Sponsor
- Meyer Children's Hospital IRCCS
Hypothyroidism
Randomized Crossover Trial for the Evaluation of the Possible Effects in the Intestine of Two Different Pharmaceutical Forms of L - Thyroxine in Patients With Primary Acquired Hypothyroidism
Thyroid disorders, in particular hypothyroidism, are associated with gastrointestinal impairment, such as celiac disease. A study reported an increased prevalence of celiac disease in a large cohort of children affected by…
- Trial name
- NCT02917863
- Testing
- L-Thyroxine (tablet, per os), L-Thyroxine (oral drops, solution)
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Meyer Children's Hospital IRCCS
Retinopathy of Prematurity
Safety and Efficacy of Propranolol Eye Drops in Treating Retinopathy of Premature
The aim of the present study is to evaluate the safety and efficacy of propranolol eye drops in preterm newborns with a precocious stage of retinopathy of prematurity (ROP).
- Trial name
- DROP-PROP (NCT02014454)
- Testing
- Propranolol eye drops
- Where
- 2 sites in Italy
- Volunteers
- 23 people
- Sponsor
- Meyer Children's Hospital IRCCS
Hypoxic Ischemic Encephalopathy
Safety and Efficacy of Topiramate in Neonates With Hypoxic Ischemic Encephalopathy Treated With Hypothermia
The purpose of this study is to determine whether the administration of topiramate to newborns with hypoxic-ischemic encephalopathy potentiates the neuroprotective effect of treatment with hypothermia.
- Trial name
- NeoNATI (NCT01241019)
- Testing
- Topiramate in newborns with hypoxic ischemic encephalopathy treated with therapeutic hypothermia
- Where
- 2 sites in Italy
- Volunteers
- 64 people
- Sponsor
- Meyer Children's Hospital IRCCS
Retinopathy of Prematurity
Safety and Efficacy of Propranolol in Newborns With Retinopathy of Prematurity
The purpose of this study is to determine whether the administration of propranolol is effective in the treatment of the retinopathy of the prematurity.
- Trial name
- PROP-ROP (NCT01079715)
- Testing
- Propranolol
- Where
- 2 sites in Italy
- Volunteers
- 52 people
- Sponsor
- Meyer Children's Hospital IRCCS