Clinical trials: sponsored by Minia University
Consecutive Exotropia, Medial Rectus Advancement
Surgical Management of Consecutive Exotropia : Surgical Choice Based on the Angle of Deviation
Aim of the work: to have a surgical plan for consecutive exotropia based on the degree of the angle of deviation. Setting: Department of ophthalmology, Faculty of medicine, Minia University, Egypt.
- Trial name
- NCT07848139
- Testing
- patients with angle of deviation of 30 PD or less had undergone bilateral lateral rectus recession
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
TEETH EXTRACTION, Esthetic Zone Implantology
Guided Root Slice Replantation vs. Socket Shielding for Immediate Implant Placement in Esthetic Zone
The goal of this clinical trial is to learn whether two different tooth-preservation techniques work equally well when placing a dental implant right after a tooth is removed in the front of the mouth (the "esthetic zone").
- Conditions
- TEETH EXTRACTION, Esthetic Zone Implantology, Socket Shield Technique Implant Placement, Root Slicing
- Trial name
- NCT07845019
- Testing
- Guided socket shield with immediate implant, Guided Autogenous Root Slicing Replantation with Immediate Implant, Conventional Bone Augmentation with Immediate Implant
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Antireflux Mucosal Ablation, Laparoscopic Fundoplication Procedure
Antireflux Mucosal Ablation vs Fundoplication for Refractory GERD
This study compared two treatments for patients with gastroesophageal reflux disease (GERD) that did not improve with standard acid-reducing medications.
- Conditions
- Antireflux Mucosal Ablation, Laparoscopic Fundoplication Procedure, Refractory GERD, Endoscopic Therapy
- Trial name
- NCT07842354
- Testing
- Modified Antireflux Mucosal Ablation (ARMA), Laparoscopic Nissen Fundoplication
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Minia University
Caries,Dental
Efficacy of a Chitosan Dressing in Pulpotomy of Immature Permanent Teeth
Immature permanent teeth, also known as young permanent teeth, are used to describe teeth with incomplete root formation. Immature permanent teeth are prone to caries and trauma which can cause exposure and degeneration of pulp.
- Trial name
- NCT07323433
- Testing
- Chitosan Dressing
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Minia University
Esophageal Achalasia, Esophageal Motility Disorders
POEM Versus Laparoscopic Heller Myotomy With Dor Fundoplication for Esophageal Achalasia
Achalasia is a disorder of the esophagus in which the muscular valve between the esophagus and the stomach fails to relax, and the body of the esophagus loses its normal coordinated squeezing movement.
- Conditions
- Esophageal Achalasia, Esophageal Motility Disorders, Gastroesophageal Reflux
- Trial name
- POEM-HD (NCT07814027)
- Testing
- Peroral endoscopic myotomy, Laparoscopic Heller myotomy with Dor fundoplication
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Minia University
Thyroid Nodule, Thyroid Dysfunction
Postoperative Hypocalcemia After Thyroidectomy
This retrospective cohort study investigates predictors of postoperative hypocalcemia following thyroidectomy procedures at Minia University Hospital over a 10-year period (2014-2024).
- Conditions
- Thyroid Nodule, Thyroid Dysfunction, Hypocalcemia, Thyroid Cancer
- Trial name
- NCT07428057
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Minia University
Gastroesophageal Reflux Disease, Hiatal Hernia
Preoperative Predictors of Symptom Improvement After Laparoscopic Fundoplication
Laparoscopic fundoplication is the standard operation for gastroesophageal reflux disease (GERD) that does not respond adequately to medication, and it relieves reflux symptoms in most patients who are carefully selected for it.
- Conditions
- Gastroesophageal Reflux Disease, Hiatal Hernia, Esophagitis, Peptic, Barrett Esophagus
- Trial name
- NCT07809620
- Testing
- Laparoscopic Nissen fundoplication, Laparoscopic Toupet fundoplication
- Where
- Egypt
- Volunteers
- 470 people
- Sponsor
- Minia University
Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer
Mesopancreatic Excision for Pancreatic Duct Adenocarcinoma.
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with high rates of local recurrence and distant metastasis. Recent evidence suggests that mesopancreatic excision (TMpE) may improve R0 resection rates, reduce local…
- Trial name
- TMpE (NCT07148830)
- Testing
- Total Mesopancreas Excision (TMpE) (as part of Pancreaticoduodenectomy)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Pancreaticoduodenectomy, Postoperative Pancreatic Fistula
Saleh's Technique for Pancreaticojejunostomy (Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate)
This study investigates the safety and efficacy of injecting N-butyl-2-cyanoacrylate (Histoacryl®) into the pancreatic parenchyma during pancreaticoduodenectomy (PD) to enhance the security of the pancreaticojejunostomy (PJ)…
- Conditions
- Pancreaticoduodenectomy, Postoperative Pancreatic Fistula, Pancreas Cancer, Periampullary Cancer
- Trial name
- NBCA (NCT07132541)
- Testing
- Pancreatic parenchymal injection of N-butyl-2-cyanoacrylate(Histoacryl®)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Pancreas Cancer, Periampullary Cancer
Neoadjuvant vs Upfront Surgery for Resectable Pancreatic Cancer and Periampullary Cancer
Adjuvant chemotherapy after surgery significantly improved the survival of pancreatic cancer (PC) patients, but there is a problem that only about 50% of patients start adjuvant chemotherapy after pancreatectomy.
- Conditions
- Pancreas Cancer, Periampullary Cancer, Periampullary Carcinoma Resectable, Pancreatic Cancer Resectable
- Trial name
- NCT07081360
- Testing
- Neoadjuvant chemotherapy, Upfront Surgery Group
- Where
- Egypt
- Volunteers
- 262 people
- Sponsor
- Minia University
Bacterial Keratitis, Recalcitrant Infectious Keratitis
Intrastromal Moxifloxacin as an Adjunctive Therapy in Recalcitrant Bacterial Keratitis
Bacterial keratitis is a potentially sight-threatening corneal infection that is commonly treated with intensive topical antibiotics.
- Conditions
- Bacterial Keratitis, Recalcitrant Infectious Keratitis, Corneal Ulcer
- Trial name
- NCT07394257
- Testing
- Intrastromal moxifloxacin injection plus standard topical moxifloxacin therapy, Standard topical moxifloxacin therapy alone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Postoperative Pain, Irreversible Pulpitis
Impact of Cross-Sectional Design in Single-File Rotary System on Apical Debris Extrusion
Endodontic treatment aims to achieve optimal biological outcomes while minimizing patient's discomfort during and after the procedure.
- Trial name
- NCT07808684
- Testing
- AF One single-file rotary system
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Lateral Internal Sphincterotomy, Hemorrhoidectomy
Hemorrhoidectomy With or Without Lateral Internal Sphincterotomy in Management of Patients With Hemorrhoids
This study aims to compare the lateral internal sphincterotomy versus no lateral internal sphincterotomy during hemorrhoidectomy in the management of patients with hemorrhoids.
- Conditions
- Lateral Internal Sphincterotomy, Hemorrhoidectomy, Hemorrhoids
- Trial name
- NCT06884774
- Testing
- Hemorrhoidectomy with lateral internal sphincterotomy, Hemorrhoidectomy
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Minia University
Open Angle Glaucoma (OAG) Surgeries, Deep Sclerectomy
Deep Sclerectomy With Scleral Bed Fenestration Versus Trabeculectomy in Medically Uncontrolled Primary Open Angle Glaucoma Patients
this study tries to find the efficacy of adding certain modifications to deep sclerectomy in primary open angle glaucoma patients who can no be controlled by medical therapy and if it can reach trabeculectomy efficacy or not
- Conditions
- Open Angle Glaucoma (OAG) Surgeries, Deep Sclerectomy, Open Angle Glaucoma (OAG)
- Trial name
- NCT07800637
- Testing
- deep sclerectomy with scleral bed fenestration, Trabeculectomy
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Minia University
Post Operative Pain
Efficacy of a Novel Nanoparticle -Augmented Disinfection Protocol
The ultimate biological aim of endodontic therapy is to either prevent or heal apical periodontitis. Root canal treatment can fail for various reasons, such as persistent infection, missing canals, ledges, canal transportation…
- Trial name
- NCT07800403
- Testing
- Novel Nanoparticle
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Minia University
Skeletal Class III Malocclusion
Randomised Clinical Trial on 30 Class Lll Patients on Two Groups Each Group Consist of 15 Patient to Compare Between Face Mask and Ertty Appliance in Treatment of Skeletal Class Lll Deficient Maxilla.Acone Beam ct to Every Patient Before and After Treatment and a3D Ceph Traced to Every Patient.
Randomised clinical trial on 30 class lll patients on two groups each group consist of 15 patient to compare between Face mask and Ertty Appliance in Treatment of skeletal class lll Deficient maxilla.acone beam ct to every…
- Trial name
- NCT07798791
- Testing
- Protraction of maxilla using face mask appliance, Protraction of maxilla using Errty Gap appliance
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Hemodynamic Instability
Preoperative Ivabradine Doses for Hemodynamic Stability in FESS
This study compares two different preoperative doses of a heart-rate-lowering medication called ivabradine in patients undergoing endoscopic sinus surgery under general anesthesia.
- Trial name
- NCT07797946
- Testing
- Ivabradine 5 mg/5 mg regimen, Ivabradine 5 mg/7.5 mg regimen
- Volunteers
- 60 people
- Sponsor
- Minia University
Ephedrine, Norepinephrine
Intermittent Bolus Doses of Phenylephrine, Norepinephrine and Ephedrine for the Management of Spinal Induced Hypotension in Preeclamptic Patients
intermittent bolus doses of phenylephrine, norepinephrine and ephedrine for the management of spinal induced hypotension in preeclamptic patients
- Trial name
- NCT07795710
- Testing
- Group 1 (P), Group 2( N), Group 3( E)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Minia University
Post Operative Pain
Influence of Irrigant Delivery Systems on the Incidence of Postoperative Discomfort in Oval Canals
The main aim of endodontic therapy is to disinfect the entire root canal system (RCS), which requires the elimination of microorganisms and microbial components. This goal is pursued by chemo-mechanical debridement of the RCS.
- Trial name
- NCT07788027
- Testing
- Sodium hypochlorite 5.25%
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Minia University
Post Operative Pain
Effect of NeoSEALER FLO and AH Plus Resin Sealer on Postoperative Pain and Healing of Periapical Lesions
Tissue repair is an essential process that reestablishes tissue integrity and regular function. Nevertheless, different therapeutic factors and clinical conditions may interfere in this process of periapical healing.The success…
- Trial name
- NCT07785973
- Testing
- AH plus sealer
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Minia University