Clinical trials: sponsored by Minia University
Endodontically Treated Teeth
Outcome of NSRCT Versus VPT in Management of Teeth with Symptomatic Irreversible Pulpitis Associated with Apical Periodontitis
Pulpitis is the pulpal inflammation in response to irritants which are either microbial, chemical, or physical (mechanical and thermal) in origin.
- Trial name
- NCT06226870
- Testing
- root canal tretment, biodentin VPT, PRF
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Minia University
Traumatic Brain Injury
Comparison Between Effect of Vitamin D Versus Dexmedetomidine in Patients with Head Trauma Using Interleukin 6
in this study the investigators compare between the neuroprotective effect of vitamin d versus dexmedetomidine in patients with traumatic brain injury using interleukin 6 as inflammatory biomarker
- Trial name
- NCT06565338
- Testing
- Dexmedetomidine, Vitamin D3
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Immature Teeth, Necrotic Pulp
Efficacy of Integrated Nano-technology in Revascularization of Immature Necrotic Teeth
This trial aims to study the effect of photoactivated disinfection using Diod laser (810 nm) to activate photosensitive nanoparticle chitosan as an endodontic irrigant versus sodium hypochlorite followed by saline and then EDTA…
- Trial name
- NCT06631885
- Testing
- regenerative endodontic procedure using blood clot according to AAE, regenerative endodontic procedure using photo activated nanochitosan 2%
- Volunteers
- 20 people
- Sponsor
- Minia University
Infection Wound, Antibiotic Resistant Infection
The Role of Postoperative Antibiotics in Laparoscopic Cholecystectomy
Comparison between postoperative parenteral prophylactic antibiotics, and oral antibiotics regarding the incidence of post laparoscopic cholecystectomy infection.
- Trial name
- NCT06607887
- Testing
- IV antibiotic, Oral antibiotic
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Minia University Hospital
Sepsis, Severe
Accuracy of Venous Excess Ultrasound (VEXUS) Score Versus Central Venous Pressure in Patients With Severe Sepsis
assessing septic patients with a noninvasive ultrasound protocol, and earlier identification of fluid overload to help clinicians decide whether to administer supplemental fluid therapy or suspend its administration and to…
- Trial name
- NCT06586931
- Volunteers
- 60 people
- Sponsor
- Minia University
Corneal Ulcer of Bilateral Eyes
Studying the Effect of Ethanol Applied on the Corneal Surface During PRK Surgery.
The goal of this observational study is to learn about the effects of the duration of ethanol contact with the corneal surface. The main question it aims to answer is: Does this affect the behavior of corneal epithelial healing?
- Trial name
- NCT06540131
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Minia University
Acquired Nasolacrimal Duct Obstruction
Evaluation of Different Methods of Posterior Flap Management in External Dacryocystorhinostomy
The aim of DCR is to form a new, mucosa-lined pathway between the lacrimal sac and the nasal cavity where tears can bypass a lacrimal obstruction and drain directly in the nose.
- Trial name
- NCT06530264
- Testing
- DCR
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Glaucoma
Anterior Segment Changes After Pars Plana Vitrectomy With SO Using AS-OCT
To evaluate changes in ACA induced by pars plana vitrectomy with SO 1000cs injection in vitreo-retinal surgery in phakic eyes using AS-OCT and changes in the IOP preoperatively, post-operatively and post-silicone oil evacuation.
- Trial name
- NCT06524661
- Testing
- AS-OCT after vitrectomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Unilateral Cleft Lip and Palate
Effect of Using Two Different Construction Techniques of Nasoalveolar Molding Devices in Unilateral Cleft Lip and Palate Patients
This study includes Three Dimensional Evaluation of Maxillary Arch Changes After Using Two Different Construction Techniques of Nasoalveolar Molding Devices in Unilateral Cleft Lip and Palate Patients (Randomized Controlled…
- Trial name
- NCT05837780
- Testing
- Nasoalveolar molding device
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Minia University
Corneal Perforation
Role of AS-OCT in Assessment of Corneal Perforation
Assessment of healing of thin and perforated cornea after surgical treatment by anterior segment optical coherence tomography
- Trial name
- OCT (NCT06422897)
- Testing
- anterior segment optical coherence tomography
- Where
- Egypt
- Volunteers
- 13 people
- Sponsor
- Minia University
SonicFill Clinical Performance, Sonicated Bulk-fill Resin Composite
Comparison Between Sonic Fill and X-tra Fill in Clinical Performance
The present study aims to evaluate a 2-years clinical performance of sonic-activated bulk-fill resin composite material (sonic fill) in comparison to conventional bulk-fill resin composite (X-tra fill) as posterior restorations.
- Trial name
- NCT04926883
- Testing
- bulk-fill composite resin restorations
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Minia University
Acute Pain
Clinical Efficacy of Prophylactic Intravenous Neostigmine and Atropine in Preventing Post-Dural Puncture Headache Among Parturient Undergoing Spinal Anesthesia for Cesarean Section: A Double-blind Randomized Placebo-controlled Trial
Post dural puncture headache is a distressing issue, many measures tried to treat symptoms but few delt with prevention.
- Trial name
- NCT06493838
- Testing
- intravenous 50 mL of saline injection of 0.9% after umbilical cord clamping., Neostigmine 20μg/kg (Neostigmine Methylsulphate 0.5 mg, Amriya Pharm.Ind.) and atropine 0.01 mg/kg (diluted in 50 ml saline; 0.9% for 10 min) following umbilical cord clamping.
- Volunteers
- 180 people
- Sponsor
- Minia University
Placenta Accreta Spectrum
Comparison Between Cervical Tourniquet and Uterine Artery Ligation Prior to Segmental Resection Approach
The study will compare a modified surgical approach for preserving fertility and minimizing hemorrhage in morbidly adherent placenta during cesarean section with a cervical tourniquet against uterine artery ligation.
- Trial name
- NCT06483724
- Testing
- cervical tourniquet, uterine artery ligation
- Volunteers
- 82 people
- Sponsor
- Minia University
Chronic Pain
Trans-foraminal Lumbar Epidural Injection of Dexmedetomidine Against Magnesium Sulfate When Combined With Dexamethasone in Uni-lateral Lower Limb Radicular Pain. Multi-centeric Comparative Study
Transforaminal injection of chronic radicular lower limb injection by either dexmedetomdine or magnesuim sulfate
- Trial name
- NCT05271721
- Testing
- epidural transforaminal injection of magnesuim sulfate, epidural transforaminal injection of dexmedtemodine, transforaminal epidural injection of dexamethasone
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Minia University
Pain, Chronic
Dexmedetomidine or Hyalase : Which of Them Can Augment Lumbar Epidural Steroid Injection in Failed Back Surgery Patients. A Randomized Clinical Trial
hyalase and dexmedtemodine are well known adjuvants given epidurally to alleviate chronic back pain. Use in failed back surgery is an up to date field to hasten analgesia and py off recurrence .
- Trial name
- NCT05370963
- Testing
- Hylase versus dexmedtemodine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Chronic Cervical Radiculopathy
High Versus Standard Voltage Pulsed Radiofrequency for Cervical Nerve Roots Injection in Refractory Chronic Unilateral Cervical Radicular Pain
The goal of this interventional study is to compare efficacy of either standard versus supra-voltage radiofrequency cervical epidural injection in pain alleviation in population with chronic cervical radiculopathy.
- Trial name
- NCT05749185
- Testing
- radiofrequency high voltage, standard RF
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Primary Teeth
Direct Resin Composite Restoration of Primary Anterior Teeth Using Custom 3D Printed Templates
Esthetic restoration of primary anterior teeth is challenging. Aim of the study: Evaluation of the 12-month clinical performance of direct resin composite restoration of carious vital primary anterior teeth using custom 3D…
- Trial name
- RCT (NCT06478004)
- Testing
- Direct composite restoration of carious primary anterior teeth using custom 3D printed templates, Direct composite restoration of carious primary anterior teeth using conventional strip crowns
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Minia University
Acute Herpes Zoster Neuropathy
Ultrasound Guided Serratus Anterior Versus Erector Spinae Block in Pain Alleviation in Acute Herpes Zoster
Acute herpes zoster pain is very severe . Conventional analgesics may be of no value. Regional blocks may play a role
- Trial name
- NCT06476080
- Testing
- ultrasound guided erector spine block, Serratus anterior block
- Volunteers
- 120 people
- Sponsor
- Minia University
Tooth Decay
Effect of Aging on Micro-tensile Bond Strength and Color Stability of Self-adhesive Resin Composite
The objective of this study is to evaluate the micro-tensile bond strength of a newly self-adhesive resinous restorative material to dentin with and without application of universal bonding system (in-vitro) and to examine it's…
- Trial name
- NCT06463574
- Testing
- self-adhesive resin restoration
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Minia University
Postoperative Pain
Postoperative Pain After Pulpectomy of Primary Molars
Testing postopertive pain after pulpectomy of primary molars with endoflas using modified Wong-Baker scale of pain.
- Trial name
- NCT06424353
- Testing
- Endoflas pulpectomy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University